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TIME The Secrets to a Healthy Heart
by Editors of TIMEHeart disease is America's No. 1 killer, causing one in every four deaths. Yet new science and time-tested strategies hold the keys to having a healthy heart. In this special edition, TIME shows the remarkable resiliency of this organ and the best ways to keep it in top shape for a lifetime. Highlights include:Astonishing new advances in treating heart diseaseThe strong connection between our emotions and our cardiovascular healthPromising new drugs and proven heart-healthy diets
TIME for Kids: 300 Fantastic Facts!: Space (TIME for Kids)
by Wes LocherLearn 300 fun facts about outer space, astronauts, planets, stars, moons, and more in this out-of-this-world book for young readers!This book is packed with exciting information about space! Learn 300 fascinating facts about planets, astronauts, stars, the sun, moons, space exploration, black holes, asteroids, rockets, rovers, and more in this awesome book for space lovers and armchair astronauts of all ages.
TIME-LIFE American Inventors: A History of Genius
by The Editors of TIME-LIFEFrom Thomas Edison to Alexander Graham Bell to Benjamin Franklin to Henry Ford to the Wright Brothers, our country has been built upon a foundation of innovation. A melting pot of diversity, America harbors a collaborative spirit and inspires an exchange of ideas where what is developed by one inventor is adopted by others and pushed further, improved, and perfected, fusing different perspectives together as one.In this all-new special edition from TIME LIFE, American Inventors chronicles those minds that transformed the worlds of Industry, Information, Home, Health, and Transportation and inspired generations to come. Learn more about the inventors that went down in history for their vision, dedication and perseverance in this celebration of American ingenuity. As automotive inventor and businessman Charles Kettering once put it, although "the world hates change, it is the only thing that has brought progress" and this nation is composed of a rich history of genius that continues to inspire progress each and every day.
TITAN Interior, Surface, Atmosphere, and Space Environment
by Ingo Müller-Wodarg Caitlin A. Griffith Emmanuel Lellouch Thomas E. CravensTitan, the largest of Saturn's moons, shares remarkable similarities with Earth. Its thick atmosphere is composed primarily of nitrogen; it features the most complex organic chemistry known outside of Earth and, uniquely, hosts an analog to Earth's hydrological cycle, with methane forming clouds, rain and seas. Using the latest data from the ongoing Cassini–Huygens missions, laboratory measurements and numerical simulations, this comprehensive reference examines the physical processes that shape Titan's fascinating atmospheric structure and chemistry, weather, climate, circulation and surface geology. The text also surveys leading theories about Titan's origin and evolution, and assesses their implications for understanding the formation of other complex planetary bodies. Written by an international team of specialists, chapters offer detailed, comparative treatments of Titan's known properties and discuss the latest frontiers in the Cassini–Huygens mission, offering students and researchers of planetary science, geology, astronomy and space physics an insightful reference and guide.
TJ and the Rockets (Orca Young Readers)
by Hazel HutchinsTJ overcame his fear of cats in TJ and the Cats and his fear of ghosts in TJ and the Haunted House. Now, he's not so keen on facing his fear of failure. His best friend Seymour is determined to come up with the latest greatest invention and TJ's gran expects TJ to build a rocket. The kittens, T-Rex and Alaska, are eager to get involved. When the first rocket that TJ builds plummets out of the sky, no parachute in sight, TJ is sure that his efforts are doomed. But are they?
TMS 2021 150th Annual Meeting & Exhibition Supplemental Proceedings (The Minerals, Metals & Materials Series)
by The Minerals, Metals & Materials SocietyThis collection presents papers from the 150th Annual Meeting & Exhibition of The Minerals, Metals & Materials Society.
TMS 2023 152nd Annual Meeting & Exhibition Supplemental Proceedings (The Minerals, Metals & Materials Series)
by The Minerals, Metals & Materials SocietyThis collection presents papers from the 152nd Annual Meeting & Exhibition of The Minerals, Metals & Materials Society.
TMS and Neuroethics (Advances in Neuroethics)
by Veljko Dubljević Jonathan R. YoungAs transcranial magnetic stimulation (TMS) continues to expand from a tool of neuroscience research into a growing array of clinical applications, it presents a number of open questions that both invite and complicate ethical evaluation. Empirically supported concerns remain regarding interactions between TMS and psychiatric medications or other interventions, the potential for adverse effects in stimulated brain regions, and whether modulation of brain activity—particularly via changes in oscillatory states—might affect aspects of personhood. This volume explores the ethical landscape surrounding TMS in both research and clinical settings. Prior neuroethics literature has largely focused on theoretical implications of neurostimulation technologies, including conceptual clarification (e.g., invasiveness) and normative questions regarding the alignment of these technologies with societal values. However, while some empirical work has captured perspectives from TMS patients, many key voices—such as those of family members, clinicians, and underrepresented communities—have remained absent from scholarly discussions. Spanning historical reflection, theoretical debate, empirical analysis, and clinical insight, this collection features contributions from scholars and practitioners working at the intersection of neuroethics, neuroscience, psychiatry, and biomedical engineering. Part I of the volume offers historical and theoretical reflections, including the origins and growth of TMS research, racial disparities in access and participation, caregiver perspectives, and emerging issues related to cognitive enhancement, non-clinical use, and applications in social neuroscience and creativity. Part II turns to new directions and ethical issues in clinical TMS research, addressing treatment subgrouping, adolescent and geriatric use, mood and substance use disorders, suicidality, and the evolving regulatory landscape. Together, these chapters provide an interdisciplinary examination of the ethical, clinical, and societal dimensions of TMS. Whether as an introduction to the neuroethics of brain stimulation or as a resource for neuroscientists, clinicians, engineers, and ethicists, this volume aims to foster greater understanding and dialogue around the responsible development and application of TMS.
TMS and tDCS for Psychiatric Disorders: Non-invasive Brain Stimulation
by Wei Zheng Yuping NingThis book primarily examines the clinical utilization of TMS (Transcranial Magnetic Stimulation) and tDCS (Transcranial Direct Current Stimulation) for various psychiatric conditions including major depressive disorder, bipolar disorder, schizophrenia, substance use disorders, obsessive-compulsive disorder, attention deficit hyperactivity disorder, autism spectrum disorders, anxiety disorders, post-traumatic stress disorder, sleep disorders, and neurocognitive disorders. This book is tailored for students in clinical psychiatry, mental health professionals, and researchers specializing in psychiatric studies. It systematically presents the safety and efficacy of TMS and tDCS in the context of psychiatric disorders, while standardizing treatment protocols and operational techniques. The ultimate goal is to provide guidance for the clinical implementation of TMS and tDCS and to promote the standardization of these treatment modalities in the future.
TNF Superfamily
by Sanjay V. KhareThe tumor necrosis factor/receptor [TNF/TNFR] superfamily consists of more than 20 transmembrane proteins with conserved N-terminal cysteine-rich domains [CRDs] in the extracellular ligand binding region. Members have wide tissue distribution and play important roles in biological processes such as lymphoid and neuronal development, innate and adaptive immune response, and cellular homeostasis. The chapters of this book address some of the most interesting functions of the TNF/TNFR superfamily.
TNPSC Combined Group IV and VAO Part-2 Science - Competitive Exam: TNPSC ஒருங்கிணைக்கப்பட்ட Group IV மற்றும் VAO தேர்வு பகுதி இரண்டு அறிவியல்
by V V K SubburasuTNPSC ஒருங்கிணைந்த Group IV மற்றும் VAO போட்டித் தேர்வு – பகுதி 2 அறிவியல் புத்தகம், தமிழ்நாடு பொது சேவை ஆணையம் (TNPSC) தேர்வுக்குத் தயாராகும் தேர்வாளர்களுக்கான முழுமையான வழிகாட்டியாகும். இப்புத்தகம் இயற்பியல், வேதியியல் மற்றும் உயிரியல் உள்ளிட்ட பல்வேறு அறிவியல் தலைப்புகளை விரிவாக எடுத்துரைக்கிறது. அலகுகளின் அளவீடுகள், இயக்கவியல், வெப்பவியல், ஒளியியல், ஒலியியல், மின்காந்தவியல், மூலக்கூறுகள் வரிசை அமைப்பு, அமிலங்கள், தாவர மற்றும் உயிரியல் என பல பிரிவுகளை விளக்கமாக வழங்குகிறது. ஒவ்வொரு பகுதியும் எடுத்துக்காட்டுகள், பயிற்சி கேள்விகள் மற்றும் விளக்கமான பதில்களுடன் அமையப்பட்டுள்ளது. இப்புத்தகம் TNPSC போட்டித் தேர்வில் வெற்றிபெறத் தேவையான அறிவு மற்றும் திறன்களை பெற உதவும் வகையில் வடிவமைக்கப்பட்டுள்ளது.
TP-Model Transformation-Based-Control Design Frameworks
by Péter BaranyiThis book covers new aspects and frameworks of control, design, and optimization based on the TP model transformation and its various extensions. The author outlines the three main steps of polytopic and LMI based control design: 1) development of the qLPV state-space model, 2) generation of the polytopic model; and 3) application of LMI to derive controller and observer. He goes on to describe why literature has extensively studied LMI design, but has not focused much on the second step, in part because the generation and manipulation of the polytopic form was not tractable in many cases. The author then shows how the TP model transformation facilitates this second step and hence reveals new directions, leading to powerful design procedures and the formulation of new questions. The chapters of this book, and the complex dynamical control tasks which they cover, are organized so as to present and analyze the beneficial aspect of the family of approaches (control, design, and optimization). Additionally, the book aims to convey simple TP modeling; a new convex hull manipulation based possibilities for optimization; a general framework for stability analysis; standardized modeling and system description; relaxed and universal LMI based design framework; and a gateway to time-delayed systems.
TRANSBALTICA XIII: Proceedings of the 13th International Conference TRANSBALTICA, September 15-16, 2022, Vilnius, Lithuania (Lecture Notes in Intelligent Transportation and Infrastructure)
by Irina Yatskiv Olegas Prentkovskis Paulius Skačkauskas Pavlo Maruschak Mykola KarpenkoThis book reports on innovative research and developments in the broad field of transportation. It covers solutions relating to intelligent vehicles and infrastructure, energy and combustion management, vehicle dynamics and engineering, as well as research on railway transport, aerospace technologies, logistics and security. Contributions are based on peer-reviewed papers presented at the 13th international scientific conference "Transbaltica: Transportation Science and Technology", held on September 15-16, 2022, at Vilnius Gediminas Technical University, in Vilnius, Lithuania. All in all, this book offers extensive information on modern transport systems, with a good balance of theory and practice.
TRENDS IN OIL SUPPLY AND DEMAND, THE POTENTIAL FOR PEAKING OF CONVENTIONAL OIL PRODUCTION, AND POSSIBLE MITIGATION OPTIONS: A Summary Report of the Workshop
by National Research Council of the National AcademiesRecent events and analyses have suggested that global production of oil might peak sometime within the next few years to the next one or two decades. Other analyses, however, conclude that oil supply can meet global demand for some decades to come and that oil production peaking is much further off. To explore this issue, the NRC held a workshop, funded by the Department of Energy, bringing together analysts representing these different views. The workshop was divided into four main sessions: setting the stage; future global oil supply and demand balance; mitigation options and time to implementation; and potential follow-up activities. This report provides a summary of the workshop including the key points, issues and questions raised by the participants, and it identifies possible topics for follow-up studies. No consensus views, conclusions, or recommendations are presented.
TRP Channels (Methods in Signal Transduction Series)
by Michael X. ZhuThe rapid expansion of the TRP field has generated a large amount of excellent original work across many different research fields. However, investigators are not necessarily familiar with the pros and cons of the variety of methods used to study TRP channels. Because of functional and genetic diversity, as well as the different physiological roles
TRP Channels in Drug Discovery, Volume I
by Arpad Szallasi Tamás BíróRecent findings have implied a distinct therapeutic potential for drugs targeting Transient Receptor Potential (TRP) channels in a wide variety of diseases, many with no existing satisfactory treatment options. Thus, the TRP superfamily of ion channels has attracted a great deal of well-deserved attention. TRP Channels in Drug Discovery provides a thorough collection of the most up-to-date reviews and protocols on the subject, coming from top experts in the field. Volume I presents a series of state-of-the-art minireviews on the most interesting TRP channels (from TRPA1 to TRPV4), as well as TRP-related protocols involving airways and the genitourinary tract. Written for the Methods in Pharmacology and ToxicologyTM series, this work includes the kind of detailed description and key implementation advice that ensures successful results in the lab. Comprehensive and cutting-edge, TRP Channels in Drug Discovery serves as an ideal reference for graduate students in academic laboratories as well as for pharmaceutical scientists developing new drugs and clinicians interested in novel drugs in the pipeline.
TRP Channels in Drug Discovery, Volume II
by Arpad Szallasi Tamás BíróRecent findings have implied a distinct therapeutic potential for drugs targeting Transient Receptor Potential (TRP) channels in a wide variety of diseases, many with no existing satisfactory treatment options. Thus, the TRP superfamily of ion channels has attracted a great deal of well-deserved attention. TRP Channels in Drug Discovery provides a thorough collection of the most up-to-date reviews and protocols on the subject, coming from top experts in the field. Volume II presents practical methodologies involving models for disorders of the cardiovascular system, the brain, skin, the metabolic system, as well as colitis, cancer, thermosensation, and musculoskeletal disorders. Written for the Methods in Pharmacology and ToxicologyTM series, this work includes the kind of detailed description and key implementation advice that ensures successful results in the lab.<P><P> Comprehensive and cutting-edge, TRP Channels in Drug Discovery serves as an ideal reference for graduate students in academic laboratories as well as for pharmaceutical scientists developing new drugs and clinicians interested in novel drugs in the pipeline.
TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades (Frontiers in Neuroscience)
by Wolfgang B. Liedtke Stefan HellerSince the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st
TRP-Mediated Signaling (Methods in Signal Transduction Series)
by Michael Xi ZhuThe field of transient receptor potential (TRP) channels has gained momentum in recent years not only because of the 2021 Nobel Prize in Physiology or Medicine awarded to David Julius and Ardem Patapoutian for their discoveries of receptors for temperature and touch, but also because of the growing appreciation of the diverse and important physiological and pathophysiological functions of this diverse family of cation channels. In the past decade, there have been important discoveries in the TRP field: resolution of the 3-D structures of major subfamilies using single-particle cryogenic electron microscopy and X-ray crystallography, identification and development of selective agonists and antagonists for most TRP subfamily members, discovery of new human diseases associated with TRP gene mutations, as well as improved understanding of TRP channel function and regulation in various systems. These new discoveries are addressed in TRP-Mediated Signaling, a volume in the Methods in Signal Transduction book series.Key Features• Summarizes recent advances in the study of TRP channels• Written by a team of leading international researchers• Reviews physiological and pathophysiological functions of TRP channels• Identifies diseases associated with TRP gene mutations• Examines the evolution of temperature-sensing TRP channels
Tabakschwärmer, Bücherwürmer und Turbo-Socken: Chemische Schwärmereien aus 10 Jahren Ausgeforscht
by Michael GroßDieses Buch präsentiert 70 Merkwürdigkeiten der „Ausgeforscht“-Glossen der Nachrichten aus der Chemie von Michael Groß. Obskure Aspekte und Meldungen aus der Wissenschaft werden aufgespießt und die Lesenden damit sowohl zum Schmunzeln als auch zum Nachdenken angeregt. Eingehend analysiert, in Kakao inkubiert und in Heiterkeit aufgelöst wird dabei auch die Wechselwirkung zwischen Wissenschaft und Technologie, dem menschlichen Alltagsleben und Konsumverhalten: von stinkenden Socken bis hin zu den perlenden Gasblasen des Champagner.Der wissenschaftliche Hintergrund der Glossen erstreckt sich von der Biologie über die Chemie bis hin zur Quantenmechanik - der alltäglich-kuriose Vordergrund von neumodischen, völlig überflüssigen Erfindungen bis hin zu traditionellen Grundnahrungsmitteln wie Bier und Wein.Der Autor Michael Groß studierte Chemie und erforschte am Oxford Centre for Molecular Sciences die biophysikalische Chemie der Proteine. Heute lebt er als freier Wissenschaftsjournalist in Oxford und schreibt regelmäßig Sachbücher und Beiträge u.a. für Spektrum der Wissenschaft, Chemie in unserer Zeit und Nachrichten aus der Chemie. 2014 wurde er von der Gesellschaft Deutscher Chemiker mit dem GDCh-Preis für Journalisten und Schriftsteller ausgezeichnet.
Table Wines: The Technology of Their Production
by M. A. Amerine M.A. JoslynThis title is part of UC Press's Voices Revived program, which commemorates University of California Press’s mission to seek out and cultivate the brightest minds and give them voice, reach, and impact. Drawing on a backlist dating to 1893, Voices Revived makes high-quality, peer-reviewed scholarship accessible once again using print-on-demand technology. This title was originally published in 1970.
Tableau Prep: Self-service Data Preparation For Better Analysis
by Carl AllchinFor self-service data preparation, Tableau Prep is relatively easy to use—as long as you know how to clean and organize your datasets. Carl Allchin, from The Information Lab in London, gets you up to speed on Tableau Prep through a series of practical lessons that include methods for preparing, cleaning, automating, organizing, and outputting your datasets.Based on Allchin’s popular blog, Preppin’ Data, this practical guide takes you step-by-step through Tableau Prep’s fundamentals. Self-service data preparation reduces the time it takes to complete data projects and improves the quality of your analyses. Discover how Tableau Prep helps you access your data and turn it into valuable information.Know what to look for when you prepare dataLearn which Tableau Prep functions to use when working with data fieldsAnalyze the shape and profile of your datasetOutput data for analysis and learn how Tableau Prep automates your workflowLearn how to clean your dataset using Tableau Prep functionsExplore ways to use Tableau Prep techniques in real-world scenariosMake your data available to others by managing and documenting the output
Tableau Strategies: Solving Real, Practical Problems with Data Analytics
by Ann Jackson Luke StankeIf you want to increase Tableau's value to your organization, this practical book has your back. Authors Ann Jackson and Luke Stanke guide data analysts through strategies for solving real-world analytics problems using Tableau. Starting with the basics and building toward advanced topics such as multidimensional analysis and user experience, you'll explore pragmatic and creative examples that you can apply to your own data.Staying competitive today requires the ability to quickly analyze and visualize data and make data-driven decisions. With this guide, data practitioners and leaders alike will learn strategies for building compelling and purposeful visualizations, dashboards, and data products. Every chapter contains the why behind the solution and the technical knowledge you need to make it work.Use this book as a high-value on-the-job reference guide to TableauVisualize different data types and tackle specific data challengesCreate compelling data visualizations, dashboards, and data productsLearn how to generate industry-specific analyticsExplore categorical and quantitative analysis and comparisonsUnderstand geospatial, dynamic, statistical, and multivariate analysisCommunicate the value of the Tableau platform to your team and to stakeholders
Tabula Raza: Mapping Race and Human Diversity in American Genome Science (Atelier: Ethnographic Inquiry in the Twenty-First Century #14)
by Duana FullwileyDuana Fullwiley has penned an intimate chronicle of laboratory life in the genomic age. She presents many of the influential scientists at the forefront of genetics who have redefined how we practice medicine and law and understand ancestry in an era of big data and waning privacy. Exceedingly relatable and human, the scientists in these pages often struggle for visibility, teeter on the tightrope of inclusion, and work tirelessly to imprint the future. As they actively imagine a more equal and just world, they often find themselves ensnared in reproducing timeworn conceits of race and racism that can seed the same health disparities they hope to resolve. Nothing dynamic can live for long as a blank slate, an innocent tabula rasa. But how the blank slate of the once-raceless human genome became one of racial differences, in various forms of what Fullwiley calls the tabula raza, has a very specific and familiar history—one that has cycled through the ages in unexpected ways.
Tackling Long-Term Global Energy Problems: The Contribution of Social Science
by Daniel Spreng Thomas Flüeler David L. Goldblatt Jürg MinschThis book makes a case for a multidisciplinary and transdisciplinary approach to energy research--one that brings more of the social sciences to bear. Featuring eight studies from across the spectrum of the social sciences, each applying multiple disciplines to one or more energy-related problems, the book demonstrates the strong analytical and policy-making potential of such a broadened perspective. Case studies include: energy transitions of households in developing countries, the 'curse of oil', politics and visions for renewables, economics and ethics in emissions trading, and carbon capture and storage.