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The Big Book on Small Heat Shock Proteins

by Robert M. Tanguay Lawrence E. Hightower

Based upon a workshop entitled "The Small HSP World" held in Québec 2-5 October 2014. Twenty-five scientists provided chapters for the book. The chapters are from the best scientists currently working in this field. These colleagues include Arrigo, Benesch, Benjamin, Buchner-Haslbeck-Weinkauf, Benndorf, Boelens, Carra, Chang, Currie, Ecroyd, Emanuelsson, Fu, Garrido, Golenhofen, Gusev, Hightower, Kampinga, Lavoie, MacRae, Quinlan, Tanguay, Vierling, Vigh, Weeks and Wu. Briefly, the book starts with the structure of small heat shock proteins, moving to their functions and finishing with their involvement in diseases. Although this is quite broad, the structural aspect will be the unifying theme of the book.

The Big Dinosaur Dig (Dk Readers: Level 3 Ser.)

by Esther Ripley

NIMAC-sourced textbook

The Big Dipper (Let's-read-and-find-out Science 1 Ser.)

by Franklyn M. Branley

Explains basic facts about the Big Dipper, including which stars make up the constellation, how its position changes in the sky, and how it points to the North Star.

The Big Fat Surprise: Why Butter, Meat and Cheese Belong in a Healthy Diet

by Nina Teicholz

A New York Times bestseller Named one of The Economist's Books of the Year 2014 Named one of The Wall Street Journal's Top Ten Best Nonfiction Books of 2014 Kirkus Reviews Best Nonfiction Books of 2014 Forbes's Most Memorable Healthcare Book of 2014 In The Big Fat Surprise, investigative journalist Nina Teicholz reveals the unthinkable: that everything we thought we knew about dietary fat is wrong. She documents how the low-fat nutrition advice of the past sixty years has amounted to a vast uncontrolled experiment on the entire population, with disastrous consequences for our health.For decades, we have been told that the best possible diet involves cutting back on fat, especially saturated fat, and that if we are not getting healthier or thinner it must be because we are not trying hard enough. But what if the low-fat diet is itself the problem? What if the very foods we've been denying ourselves--the creamy cheeses, the sizzling steaks--are themselves the key to reversing the epidemics of obesity, diabetes, and heart disease? In this captivating, vibrant, and convincing narrative, based on a nine-year-long investigation, Teicholz shows how the misinformation about saturated fats took hold in the scientific community and the public imagination, and how recent findings have overturned these beliefs. She explains why the Mediterranean Diet is not the healthiest, and how we might be replacing trans fats with something even worse. This startling history demonstrates how nutrition science has gotten it so wrong: how overzealous researchers, through a combination of ego, bias, and premature institutional consensus, have allowed dangerous misrepresentations to become dietary dogma. With eye-opening scientific rigor, The Big Fat Surprise upends the conventional wisdom about all fats with the groundbreaking claim that more, not less, dietary fat--including saturated fat--is what leads to better health and wellness. Science shows that we have been needlessly avoiding meat, cheese, whole milk, and eggs for decades and that we can now, guilt-free, welcome these delicious foods back into our lives.

The Big Fix: Seven Practical Steps to Save Our Planet

by Hal Harvey Justin Gillis

An engaging, accessible citizen&’s guide to the seven urgent changes that will really make a difference for our climate—and how we can hold our governments accountable for putting these plans into action.Dozens of kids in Montgomery County, Maryland, agitated until their school board committed to electric school buses. Mothers in Colorado turned up in front of an obscure state panel to fight for clean air. If you think the only thing you can do to combat climate change is to install a smart thermostat or cook plant-based burgers, you&’re thinking too small. That&’s where The Big Fix comes in, offering everyday citizens a guide to the seven essential changes our communities must enact to bring our greenhouse gas emissions down to zero—and sharing stories of people who are making those changes reality. Energy policy advisor Hal Harvey and longtime New York Times reporter Justin Gillis hone in on the seven areas where ambitious but eminently practical changes will have the greatest effect: electricity production, transportation, buildings, industry, urbanization, use of land, and investment in promising new green technologies. In a lively, jargon-free style, the pair illuminate how our political economy really works, revealing who decides everything from what kind of power plants to build to how efficient cars must be before they&’re allowed on the road to how much insulation a new house requires—and how we can insert ourselves into all these decisions to ensure that the most climate-conscious choices are being made. At once pragmatic and inspiring, The Big Fix is an indispensable action plan for citizens looking to drive our country&’s greenhouse gas emissions down to zero—and save our climate.

The Big Freeze: A Reporter's Personal Journey into the World of Egg Freezing and the Quest to Control Our Fertility

by Natalie Lampert

A fascinating investigation into the lucrative, minimally regulated, fast-growing industry of egg freezing, from a young reporter on a personal journey into the world of cutting-edge reproductive medicine&“An engaging and groundbreaking book.&”—Toni Weschler, MPH, author of Taking Charge of Your FertilityOvaries. Most women have two; journalist Natalie Lampert has only one. Then, in her early twenties, she almost lost it, along with her ability to ever have biological children. Doctors urged her to freeze her eggs, and Lampert started asking questions. The Big Freeze is the story of Lampert&’s personal quest to investigate egg freezing, as well as the multibillion-dollar femtech industry, in order to decide the best way to preserve her own fertility. She attended flashy egg-freezing parties, visited high-priced fertility clinics, talked to dozens of women who froze their eggs, toured the facility in Italy where the technology was developed, and even attended a memorial service for thousands of accidentally destroyed embryos. What was once science fiction is now simply science: Fertility can be frozen in time. Between 2009 and 2022, more than 100,000 women in the United States opted to freeze their eggs. Along with in vitro fertilization, egg freezing is touted as a way for women to &“have it all&” by conquering their biological clocks, in line with the global trend of delaying childbirth. A generation after the Pill, this revolutionary technology offers a new kind of freedom for women. But does egg freezing give women real agency or just the illusion of it?A personal and deeply researched guide to the pros, cons, and many facets of this wildly popular technology, The Big Freeze is a page-turning exploration of the quest to control fertility, with invaluable information that answers the questions women have been afraid to ask—or didn&’t know they should ask in the first place.

The Big Ideas in Science: A complete introduction

by Jon Evans

By the simple expedient of asking questions and conducting experiments to answer them, science has transformed our understanding of the world. It has made us who we are, and revealed a universe that is older, bigger and stranger than we could ever have imagined.The Big Ideas in Science is an accessible and easy-to-use introduction to the scientific world, what it has achieved over the past few hundred years and what it promises for the future. Covering everything from the Big Bang to global warming, it provides everything you need to know in one book.You will learn what science has discovered about matter, space, energy, life, weather and information, and how we have transformed these discoveries into our modern technologies. You will witness the birth of the solar system, follow ocean currents for thousands of miles, ride on beams of light and, ultimately, gain a deeper understanding of issues as complex as global warming, and as controversial as synthetic life.ABOUT THE SERIESThe Complete Introduction series from Teach Yourself is the ultimate one-stop guide for anyone wanting a comprehensive and accessible entry point into subjects as diverse as philosophy, mathematics, psychology, economics and practical electronics. Loved by students and perfect for general readers who simply want to learn more about the world around them, these books are your first choice for discovering something new.

The Big Ideas in Science: A complete introduction

by Jon Evans

By the simple expedient of asking questions and conducting experiments to answer them, science has transformed our understanding of the world. It has made us who we are, and revealed a universe that is older, bigger and stranger than we could ever have imagined.The Big Ideas in Science is an accessible and easy-to-use introduction to the scientific world, what it has achieved over the past few hundred years and what it promises for the future. Covering everything from the Big Bang to global warming, it provides everything you need to know in one book.You will learn what science has discovered about matter, space, energy, life, weather and information, and how we have transformed these discoveries into our modern technologies. You will witness the birth of the solar system, follow ocean currents for thousands of miles, ride on beams of light and, ultimately, gain a deeper understanding of issues as complex as global warming, and as controversial as synthetic life.ABOUT THE SERIESThe Complete Introduction series from Teach Yourself is the ultimate one-stop guide for anyone wanting a comprehensive and accessible entry point into subjects as diverse as philosophy, mathematics, psychology, economics and practical electronics. Loved by students and perfect for general readers who simply want to learn more about the world around them, these books are your first choice for discovering something new.

The Big Necessity: The Unmentionable World of Human Waste and Why It Matters

by Rose George

Delving deep into the history and implications of a daily act that dare not speak its name, The Big Necessity is on its way to removing the taboo on bodily waste something common to all and as natural as breathing.

The Big Picture

by David Suzuki David Taylor

Whether he's discussing how to reconcile economy with ecology, why a warmer world will result in more poison ivy, why Britney Spears gets more hits on Google than global warming does, or why we might need to start eating jellyfish for supper, David Suzuki points the direction we must take as a society if we hope to meet the environmental challenges we face in our still-young century. Covering suburban sprawl, sustainable transportation, food shortages, biodiversity, technology, public policy, and more, The Big Picture not only identifies the problems we face but proposes solid, science-based solutions. These engaging essays look beyond environmental challenges to examine the forces that are preventing real change from occurring. Together they tell the story of a species struggling to come to grips with its own biological nature, a nature we must ultimately embrace to live in balance with the systems that sustain us.

The Big Picture: On the Origins of Life, Meaning, and the Universe Itself

by Sean Carroll

<P>Already internationally acclaimed for his elegant, lucid writing on the most challenging notions in modern physics, Sean Carroll is emerging as one of the greatest humanist thinkers of his generation as he brings his extraordinary intellect to bear not only on Higgs bosons and extra dimensions but now also on our deepest personal questions. <P>Where are we? Who are we? Are our emotions, our beliefs, and our hopes and dreams ultimately meaningless out there in the void? Does human purpose and meaning fit into a scientific worldview? <P>In short chapters filled with intriguing historical anecdotes, personal asides, and rigorous exposition, readers learn the difference between how the world works at the quantum level, the cosmic level, and the human level--and then how each connects to the other. <P>Carroll's presentation of the principles that have guided the scientific revolution from Darwin and Einstein to the origins of life, consciousness, and the universe is dazzlingly unique. Carroll shows how an avalanche of discoveries in the past few hundred years has changed our world and what really matters to us. <P>Our lives are dwarfed like never before by the immensity of space and time, but they are redeemed by our capacity to comprehend it and give it meaning. <P>The Big Picture is an unprecedented scientific worldview, a tour de force that will sit on shelves alongside the works of Stephen Hawking, Carl Sagan, Daniel Dennett, and E. O. Wilson for years to come. <P><b>A New York Times Bestseller</b>

The Big Question: Why We Can’t Stop Talking About Science, Faith and God

by Alister McGrath

Richard Dawkins's groundbreaking book The God Delusion created an explosion of interest in the relation of science and faith. This often troubled relationship between science and religion was seemingly damaged by the rise of the New Atheism, which insisted that science had essentially disproved not just God but also the value of religion. There is increasing skepticism towards its often glib and superficial answers; and the big questions about faith, God and science haven't gone away--in fact, we seem to talk about them more than ever. Alister McGrath's The Big Question is an accessible, engaging account of how science relates to faith, exploring how the working methods and assumptions of the natural sciences can be theologically useful. McGrath uses stories and analogies, as well as personal accounts, in order to help readers understand the scientific and theological points he makes, and grasp their deeper significance. An extremely accomplished scientist and scholar, McGrath criticizes the evangelism of the New Atheists and paves a logical well-argued road to the compatibility between science and faith.Some of his main discussion points include:1. There is much more convergence between science and faith than is usually appreciated2. How the three great models of scientific explanation can be adapted to religious belief3. Belief in God provides a 'big picture' of reality, making sense of science's successes

The Big Questions The Universe

by Stuart Clark

The Big Questions series enables renowned experts to tackle the 20 most fundamental and frequently asked questions of a major branch of science or philosophy. Each 3000-word essay simply and concisely examines a question that has eternally perplexed enquiring minds, providing answers from history's great thinkers. This ambitious project is a unique distillation of humanity's best ideas. In Big Questions: The Universe, Dr Stuart Clark tackles the 20 key questions of astronomy and cosmology: What is the universe? How big is the universe? How old is the universe? What are stars made from? How did the Universe form? Why do the planets stay in orbit? Was Einstein right? What are black holes? How did the Earth form? What were the first celestial objects? What is dark matter? What is dark energy? Are we really made from stardust? Is there life on Mars? Are there other intelligent beings? Can we travel through time and space? Can the laws of physics change? Are there alternative universes? What will be the fate of the universe? Is there cosmological evidence for God?

The Big Questions The Universe

by Stuart Clark

The Big Questions series enables renowned experts to tackle the 20 most fundamental and frequently asked questions of a major branch of science or philosophy. Each 3000-word essay simply and concisely examines a question that has eternally perplexed enquiring minds, providing answers from history's great thinkers. This ambitious project is a unique distillation of humanity's best ideas. In Big Questions: The Universe, Dr Stuart Clark tackles the 20 key questions of astronomy and cosmology: What is the universe? How big is the universe? How old is the universe? What are stars made from? How did the Universe form? Why do the planets stay in orbit? Was Einstein right? What are black holes? How did the Earth form? What were the first celestial objects? What is dark matter? What is dark energy? Are we really made from stardust? Is there life on Mars? Are there other intelligent beings? Can we travel through time and space? Can the laws of physics change? Are there alternative universes? What will be the fate of the universe? Is there cosmological evidence for God?

The Big Questions: Evolution

by Francisco Ayala

Easy, enlightening and mind-stretching, here are answers to the 20 biggest questions of evolution and what they tell us about life on Earth.The Big Questions series is designed to let renowned experts address the 20 most fundamental and frequently asked questions of a major branch of science or philosophy. Each 3,000-word essay simply and concisely examines a question that has eternally perplexed enquiring minds, and provides answers based on the latest research. This ambitious project is a unique distillation of humanity's best ideas. In The Big Questions: Evolution, Francisco Ayala answers the 20 key questions: What is evolution? Was Darwin right? What is natural selection? What is survival of the fittest? Is evolution a random process? What is a species? What are chromosomes, genes and DNA? How do genes build bodies? What is molecular evolution? How did life begin? What is the tree of life? Am I really a monkey? What does the fossil record tell us? What is the missing link? Is intelligence inherited? Will humans continue to evolve? Can I clone myself? Where does morality come from? Is language a uniquely human attribute? Is Creationism true?

The Big Questions: Evolution

by Francisco Ayala

In The Big Questions: Evolution, one of the world's leading experts, Francisco Ayala, examines key facets of genetics, evolution and cloning. He uses the most up-to-date research to answer the 20 key questions of evolution, and investigate what they tell us about life on Earth.What is evolution? What is natural selection? Is evolution a random process? What are chromosomes, genes and DNA? What is molecular evolution? What is the tree of life? What does the fossil record tell us? Is intelligence inherited? Can I clone myself? Is language a uniquely human attribute? Was Darwin right? What is 'survival of the fittest'? What is a species? How do genes build bodies? How did life begin? Am I really a monkey? What is the missing link? Will humans continue to evolve? Where does morality come from? Is Creationism true?

The Big Questions: Evolution

by Francisco Ayala

In The Big Questions: Evolution, one of the world's leading experts, Francisco Ayala, examines key facets of genetics, evolution and cloning. He uses the most up-to-date research to answer the 20 key questions of evolution, and investigate what they tell us about life on Earth.What is evolution? What is natural selection? Is evolution a random process? What are chromosomes, genes and DNA? What is molecular evolution? What is the tree of life? What does the fossil record tell us? Is intelligence inherited? Can I clone myself? Is language a uniquely human attribute? Was Darwin right? What is 'survival of the fittest'? What is a species? How do genes build bodies? How did life begin? Am I really a monkey? What is the missing link? Will humans continue to evolve? Where does morality come from? Is Creationism true?

The Big Questions: Mind

by Richard M. Restak

'The Big Questions' series is designed to let renowned experts confront the 20 most fundamental and frequently asked questions of a major branch of science or philosophy. In 'The Big Questions: Mind' the explanations behind the 'mysteries' of our unique minds - including how they differ from our brains and how they create our awareness - are explored. Among the questions discussed are: How do brains come to exist? Is the mind more than the brain? What does it mean to be conscious? What is knowledge? Does the mind play tricks? What is the 'I' in our brain?

The Big Questions: Mind (The Big Questions)

by Richard M. Restak

'The Big Questions' series is designed to let renowned experts confront the 20 most fundamental and frequently asked questions of a major branch of science or philosophy. In 'The Big Questions: Mind' the explanations behind the 'mysteries' of our unique minds - including how they differ from our brains and how they create our awareness - are explored. Among the questions discussed are: How do brains come to exist? Is the mind more than the brain? What does it mean to be conscious? What is knowledge? Does the mind play tricks? What is the 'I' in our brain?

The Big Questions: Physics

by Michael Brooks

The Big Questions series is designed to let renowned experts address the 20 most fundamental and frequently asked questions of a major branch of science or philosophy. Each 3000-word essay simply and concisely examines a question that has eternally perplexed enquiring minds, and provides answers from history's great thinkers. This ambitious project is a unique distillation of humanity's best ideas. In Big Questions: Physics, Michael Brooks answers the 20 key questions: What is the point of physics? Is everything ultimately random? What is time? Why is there no such thing as a free lunch? What happened to Schrödinger's cat? Can I change the universe with a single glance? Are solids really solid? Which is nature's strongest force? Why does an apple fall? Do we live in a computer simulation? What is light? Is Earth's magnetic shield failing? Am I unique in the universe? Does chaos theory spell disaster? Can we travel through time? Is string theory really about strings? Why does E=mc2? What is the God Particle? Why is there something rather than nothing? What is the ultimate nature of reality?

The Big Questions: Physics

by Michael Brooks

The Big Questions series is designed to let renowned experts address the 20 most fundamental and frequently asked questions of a major branch of science or philosophy. Each 3000-word essay simply and concisely examines a question that has eternally perplexed enquiring minds, and provides answers from history's great thinkers. This ambitious project is a unique distillation of humanity's best ideas.

The Big Questions: Physics

by Michael Brooks

The Big Questions series is designed to let renowned experts address the 20 most fundamental and frequently asked questions of a major branch of science or philosophy. Each 3000-word essay simply and concisely examines a question that has eternally perplexed enquiring minds, and provides answers from history's great thinkers. This ambitious project is a unique distillation of humanity's best ideas.

The Big Questions: The Universe

by Stuart Clark

The Big Questions series enables renowned experts to tackle the 20 most fundamental and frequently asked questions of a major branch of science or philosophy. Each 3000-word essay simply and concisely examines a question that has eternally perplexed enquiring minds, providing answers from history's great thinkers. This ambitious project is a unique distillation of humanity's best ideas. In Big Questions: The Universe, Dr. Stuart Clark tackles the 20 key questions of astronomy and cosmology: What is the universe? How big is the universe? How old is the universe? What are stars made from? How did the universe form? Why do planets stay in orbit? Was Einstein right? What are black holes? How did the Earth form? What were the first celestial objects? What is dark matter? What is dark energy? Are we really made from stardust? Is there life on Mars? Are there other intelligent beings? Can we travel through time and space? Can the laws of physics change? Are there alternative universes? What will be the fate of the universe? Is there cosmological evidence for God?

The Big Ratchet: How Humanity Thrives in the Face of Natural Crisis

by Ruth Defries

Our species long lived on the edge of starvation. Now we produce enough food for all 7 billion of us to eat nearly 3,000 calories every day. This is such an astonishing thing in the history of life as to verge on the miraculous. The Big Ratchet is the story of how it happened, of the ratchets--the technologies and innovations, big and small--that propelled our species from hunters and gatherers on the savannahs of Africa to shoppers in the aisles of the supermarket. The Big Ratchet itself came in the twentieth century, when a range of technologies--from fossil fuels to scientific plant breeding to nitrogen fertilizers--combined to nearly quadruple our population in a century, and to grow our food supply even faster. To some, these technologies are a sign of our greatness; to others, of our hubris. MacArthur fellow and Columbia University professor Ruth DeFries argues that the debate is the wrong one to have. Limits do exist, but every limit that has confronted us, we have surpassed. That cycle of crisis and growth is the story of our history; indeed, it is the essence of The Big Ratchet. Understanding it will reveal not just how we reached this point in our history, but how we might survive it.

The Big Story of Being Alive: A Brilliant Book About What Makes You EXTRAORDINARY

by Neal Layton

Wherever you go, there are lots of people and no one looks quite the same. But they are all ALIVE. YOU are alive too. But what actually makes something ALIVE?There are three things that all living things have in common: they GROW, they REPRODUCE and they are made of trillions of tiny, but mightily important, organisms called CELLS.Find out all about them in this fresh, funny and fact-filled book from author and illustrator Neal Layton, you'll discover why being alive is totally AMAZING.

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