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SUMO Protocols
by Helle UlrichWhile the small ubiquitin-related modifier SUMO uses a conjugation and de-conjugation system closely related to that of ubiquitin itself, its functions are highly diverse and largely independent of the ubiquitin system. In SUMO Protocols, leading experts present a collection of methods intended to highlight important features unique to the biology of SUMO in order to support future SUMO research. The first half of the volume focuses on the identification and functional characterization of SUMO targets and interactors, while the second half covers essential biochemical methods for the manipulation of the enzymatic components of the SUMO system. Written in the highly successful Methods in Molecular BiologyTM series format, the chapters include brief introductions to the subject, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and the Notes sections, which provide tips on troubleshooting and avoiding known pitfalls. Unique and cutting-edge, SUMO Protocols provides the necessary tools for biochemists, molecular and cellular biologists as well as research-oriented clinicians not yet familiar with this vital system.
SUMO Regulation of Cellular Processes
by G. WilsonOver a decade ago, a small cellular protein of 12 kDa, with 18% homology to the well-known ubiquitin protein, was co-discovered and termed Small Ubiquitin-like Modifier, or SUMO. Sumoylation is a post-translational modification that utilizes SUMO as the modifier group covalently attached to target substrates. This state-of-the art review on the sumoylation system deals with protein modification as it pertains to regulation of diverse cellular functions. Each chapter has been written by a leading researcher and covers the role of sumoylation in fundamental biochemical activities (transcription, RNA processing, chromatin remodelling, DNA repair, nucleocytoplasmic transport, ion channel regulation, and metabolic pathways). The text also examines the part sumoylation plays in critical cellular processes such as mitosis, meiosis, differentiation, senescence, and apoptosis. Lastly, the emerging role of sumoylation in specific diseases, including cancer and diabetes as well as neurodegenerative ones, is explored with an emphasis on defining molecular mechanisms that may provide new targets for treatment or prevention. While SUMO was discovered more than 10 years ago, this is still a relatively young field, and much remains to be discovered about the biochemical and biological properties of this modification system. In just the last few years, it has become clear that sumoylation modifies hundreds of cellular proteins, and there has been increased appreciation for the breadth of cellular functions that are impacted by this post-translational modification.
SUMO Regulation of Cellular Processes
by Van G. WilsonOver a decade ago, a small cellular protein of 12 kDa, with 18% homology to the well-known ubiquitin protein, was co-discovered and termed Small Ubiquitin-like Modifier, or SUMO. Sumoylation is a post-translational modification that utilizes SUMO as the modifier group covalently attached to target substrates. This state-of-the art review on the sumoylation system deals with protein modification as it pertains to regulation of diverse cellular functions. Each chapter has been written by a leading researcher and covers the role of sumoylation in fundamental biochemical activities (transcription, RNA processing, chromatin remodelling, DNA repair, nucleocytoplasmic transport, ion channel regulation, and metabolic pathways). The text also examines the part sumoylation plays in critical cellular processes such as mitosis, meiosis, differentiation, senescence, and apoptosis. Lastly, the emerging role of sumoylation in specific diseases, including cancer and diabetes as well as neurodegenerative ones, is explored with an emphasis on defining molecular mechanisms that may provide new targets for treatment or prevention. While SUMO was discovered more than 10 years ago, this is still a relatively young field, and much remains to be discovered about the biochemical and biological properties of this modification system. In just the last few years, it has become clear that sumoylation modifies hundreds of cellular proteins, and there has been increased appreciation for the breadth of cellular functions that are impacted by this post-translational modification.
SUMO Regulation of Cellular Processes
by Van G. WilsonOver a decade ago, a small cellular protein of 12 kDa, with 18% homology to the well-known ubiquitin protein, was co-discovered and termed Small Ubiquitin-like Modifier, or SUMO. Sumoylation is a post-translational modification that utilizes SUMO as the modifier group covalently attached to target substrates. This state-of-the art review on the sumoylation system deals with protein modification as it pertains to regulation of diverse cellular functions. Each chapter has been written by a leading researcher and covers the role of sumoylation in fundamental biochemical activities (transcription, RNA processing, chromatin remodelling, DNA repair, nucleocytoplasmic transport, ion channel regulation, and metabolic pathways). The text also examines the part sumoylation plays in critical cellular processes such as mitosis, meiosis, differentiation, senescence, and apoptosis. Lastly, the emerging role of sumoylation in specific diseases, including cancer and diabetes as well as neurodegenerative ones, is explored with an emphasis on defining molecular mechanisms that may provide new targets for treatment or prevention. While SUMO was discovered more than 10 years ago, this is still a relatively young field, and much remains to be discovered about the biochemical and biological properties of this modification system. In just the last few years, it has become clear that sumoylation modifies hundreds of cellular proteins, and there has been increased appreciation for the breadth of cellular functions that are impacted by this post-translational modification.
The Sun
by David AlexanderThe latest entry in the Greenwood Guides to the Universe series explores the Sun and observes that while it is ordinary in the context of a star in the universe, its proximity to the earth has generated significant advances in the study of astronomy and physics. Alexander (astrophysics, Rice U.) explores the Sun's roles as a timekeeper and mythological entity before providing scientific data on its surface, magnetism, atmosphere and climate. Appendices include interesting facts about the Sun and a glossary of terms so that novice and advanced students, as well as general readers, can appreciate the content. Annotation ©2009 Book News, Inc., Portland, OR (booknews.com)
Sun: Ready-to-read Level 1 (Weather Ready-to-reads Ser.)
by Marion Dane BauerThis book reveals certain facts about the sun and describes why sun is vital to life.
The Sun (Scholastic News Nonfiction Readers: Space Science)
by Melanie ChrismerUpdated art of solar system shows 8 planets and their orbits instead of 9 - New Pluto book includes a list of other dwarf planets, in addition to Pluto, in our solar system - Updated information on space missions, moons, and planets - Updated Web sites for further information in back matter.
The Sun (A True Book: Our Universe)
by Cody CraneIt's bright and it's hot. It's the center of our solar system. It is our Sun. As readers journey through this book, they will discover how this amazing star came into existence, and they will learn everything about its size and makeup, its solar winds and flares, and how its light and heat affect Earth. The workings of the sun's magnetic field, sun spots, and the latest technology used to study the sun will also captivate our readers.Planets and stars, moons and galaxies! The universe is a vast and mysterious place with much to explore. And there's no better way to make amazing discoveries about space than with this reimagined series. With the latest NASA imagery, the classic structure and features of A True Book, and lively text, the titles in Our Universe bring the awe of the cosmos directly to readers. Students will come away with a wealth of knowledge about the incredible celestial bodies in our universe.This series covers Next Generation Science Standards core ideas including "The Universe and its stars" and "Earth and the solar system."
The Sun: Our Amazing Star (Penguin Core Concepts Ser.)
by Patricia Brennan DemuthBlast off and explore the star of our solar system—the Sun!Billions of stars fill the universe. But for humans, the most important star is the one closest to Earth—the Sun. From vitamin D to solar energy, the Sun provides the power necessary to sustain life on our planet. And as the center of our solar system, the strong gravitational pull from this ball of burning gas keeps all the planets in orbit. Discover the significance of the Sun and its brilliant blaze in this fascinating book!
The Sun: New Challenges
by Katya Georgieva Vladimir N. Obridko Yury A. NagovitsynThese are the proceedings of the Symposium 3 of JENAM 2011 on new scientific challenges posed by the Sun. The topics covered are 1. The unusual sunspot minimum, which poses challenges to the solar dynamo theory 2. The Sun's Terra-Hertz emission, which opens a new observational window 3. Corona wave activity 4. Space weather agents - initiation, propagation, and forecasting In 21 in-depth contributions, the reader will be presented with the latest findings.
The Sun
by Seymour SimonDescribes the nature of the sun, its origin, source of energy, layers, atmosphere, sunspots, and activity.
The Sun (Seymour Simon Science Ser.)
by Seymour SimonIn this completely updated edition of The Sun featuring beautiful full-color photographs, Seymour Simon presents a fascinating introduction to the star that is the center of our Solar System.Young readers will love exploring the wonders of the sun, from the constant nuclear explosions at its core to the sea of boiling gases that forms its surface.Seymour Simon knows how to explain science to kids and make it fun. He was a teacher for more than twenty years, has written more than 250 books, and has won multiple awards.This book includes an author's note, glossary, and index and supports the Common Core Learning Standards, Next Generation Science Standards, and the Science, Technology, Engineering, and Math (STEM) standards.
The Sun (A True Book)
by Christine Taylor-ButlerPresents information about the sun, discussing its physical characteristics, orbit, natural satellites, and the technology used to study it.
The Sun
by Claudio Vita-FinziThis is an account of the many ways in which the Sun affects our planet, how its influence has changed over the last few centuries and millennia, and the extent to which we can predict its future impact. The book is the first to integrate astronomical, geological, climatic and social aspects of the Sun. It includes a topical treatment of solar contribution to global warming, and demonstrates how wild and variable is the so-called Solar Constant. Our nearest star is a complex machine which needs to be treated with caution, and this book will equip every reader with the knowledge that is required to understand the benefits and dangers it can bring.
The Sun
by Gregory L. VogtPresents information on the composition, atmosphere, and origin of the sun.
The Sun: A Biography
by David WhitehouseIn The Sun, David Whitehouse takes us on a journey to the heart of our local star and beyond, relating how it was born, the many ways it influences life on Earth and how it will die. He recounts the many myths surrounding the Sun and the fascinating stories of scientists throughout history who have attempted to discover its secrets - occasionally at the price of their lives.The Sun explores the role of the sun for those on Earth, from the earliest civilizations that worshipped it, through its emulation in art and literature to the present day. He describes the inferno at its core, the magnetic chaos of its surface and the furthest reaches of its atmosphere that stretches beyond the planets out into the galaxy. Within our lifetimes he considers that changes in the sun will become noticeable, an issue that we ignore at our peril.Finally, David Whitehouse speculates on the future of life on Earth with a sun that must ultimately turn into a red giant. From its birth in a cloud of gas and dust, its long lifetime nurturing life on our own planet, to its death as a cosmic cinder, this is our Sun's story.
The Sun: A Biography
by Dr David WhitehouseIn The Sun, David Whitehouse takes us on a journey to the heart of our local star and beyond, relating how it was born, the many ways it influences life on Earth and how it will die. He recounts the many myths surrounding the Sun and the fascinating stories of scientists throughout history who have attempted to discover its secrets - occasionally at the price of their lives.The Sun explores the role of the sun for those on Earth, from the earliest civilizations that worshipped it, through its emulation in art and literature to the present day. He describes the inferno at its core, the magnetic chaos of its surface and the furthest reaches of its atmosphere that stretches beyond the planets out into the galaxy. Within our lifetimes he considers that changes in the sun will become noticeable, an issue that we ignore at our peril.Finally, David Whitehouse speculates on the future of life on Earth with a sun that must ultimately turn into a red giant. From its birth in a cloud of gas and dust, its long lifetime nurturing life on our own planet, to its death as a cosmic cinder, this is our Sun's story.
The Sun and How to Observe It
by Jamey L. JenkinsIn Part 1, the book describes the very latest thinking on solar physics in (mostly non-mathematical) detail, incorporating the latest results from research concerning the structure and behaviour of the Sun. There is particular emphasis on the surface features visible from the Earth, and how these are the result of the extraordinary processes that are taking place within the Sun. In Part 2, the book details the techniques for observing and imaging the Sun with commercially-available equipment. The many recent advances in optical equipment now allow amateur astronomers to observe phenomena that until recently could only be seen with the extremely expensive equipment available at universities and research observatories - notably H-alpha and Calcium-K telescopes. This is a completely up-to-date solar observing book, while providing the science background necessary for an understanding of the observations with the latest equipment. It also features the most complete solar observing and imaging guide available.
The Sun and Other Stars (World Book's Solar System and Space Exploration Library)
by Lori Meek SchuldtIntroduction to the sun and other stars, providing to primary and intermediate grade students information on their features and exploration. Includes fun facts, glossary, resource list and index.
The Sun and Photovoltaic Technologies (Green Energy and Technology)
by Tomislav PavlovicThis book covers solar energy and the use of solar radiation in connection with lighting. It provides a detailed introduction to solar energy, photovoltaic (PV) solar energy conversion, and solar lighting technologies, while also discussing all of these elements in the context of the Balkan Peninsula. In the context of solar energy, the book covers a range of elements, from the structure of the sun, to PV solar plants. It subsequently addresses the status quo of solar technologies in Bulgaria, Serbia and the Republika Srpska and analyses the development of these technologies over the years, including their economic status, and how these aspects have shaped their current status. Undergraduate and graduate students, researchers and professionals, particularly those based in the Balkans, will find this book both informative and interesting.
The Sun and the Moon (Let's-Read-and-Find-Out Science 1)
by Carolyn Cinami DeCristofanoRead and find out about the sun and the moon in this colorfully illustrated nonfiction picture book.The sun is out in the day and always has a circle shape. The moon’s shape seems to change, and you can sometimes see it in the daytime and at night. What are the sun and the moon? How are they the same and how do they differ? Hop into your spaceship and find out!With beautiful illustrations and engaging text, The Sun and the Moon guides young readers into a deeper understanding of their observations of the sun and the moon. Featuring a find-out-more section with instructions on how to keep an observation log and how to make moon ice, a glossary of new terms, and web research prompts, this book will begin children’s explorations of the sun and the moon.Recommended by Brightly as a favorite book for kids about astronomy: "This book even has a glossary and science experiments to offer kids a hands-on learning experience." Both the text and the artwork were vetted for accuracy by Bradley J. Thomson, Ph.D., Senior Research Scientist at the Boston University Center for Remote Sensing. This is a clear and appealing science book for early elementary age kids, both at home and in the classroom. It's a Level 1 Let's-Read-and-Find-Out, which means the book explores introductory concepts perfect for children in the primary grades. The 100+ titles in this leading nonfiction series are:hands-on and visualacclaimed and trustedgreat for classroomsTop 10 reasons to love LRFOs:Entertain and educate at the same timeHave appealing, child-centered topicsDevelopmentally appropriate for emerging readersFocused; answering questions instead of using survey approachEmploy engaging picture book quality illustrationsUse simple charts and graphics to improve visual literacy skillsFeature hands-on activities to engage young scientistsMeet national science education standardsWritten/illustrated by award-winning authors/illustrators & vetted by an expert in the fieldOver 130 titles in print, meeting a wide range of kids' scientific interestsBooks in this series support the Common Core Learning Standards, Next Generation Science Standards, and the Science, Technology, Engineering, and Math (STEM) standards. Let's-Read-and-Find-Out is the winner of the American Association for the Advancement of Science/Subaru Science Books & Films Prize for Outstanding Science Series.
The Sun and the Moon: The Remarkable True Account of Hoaxers, Showmen, Dueling Journalists, and Lunar Man-Bats in Nineteen
by Matthew GoodmanOn August 26, 1835, a fledgling newspaper called the Sun brought to New York the first accounts of remarkable lunar discoveries. A series of six articles reported the existence of life on the moon--including unicorns, beavers that walked on their hind legs, and four-foot-tall flying man-bats. In a matter of weeks it was the most broadly circulated newspaper story of the era, and the Sun, a working-class upstart, became the most widely read paper in the world. An exhilarating narrative history of a divided city on the cusp of greatness, and tale of a crew of writers, editors, and charlatans who stumbled on a new kind of journalism, The Sun and the Moon tells the surprisingly true story of the penny papers that made America a nation of newspaper readers.
The Sun, Energy, and Climate Change
by Eklas HossainThe Sun, Energy, and Climate Change conveys one central idea – that we can utilize energy without continuing to harm the planet by increasing our reliance on energy from the sun. This accessible guide stresses the sun’s importance as our ultimate energy source by focusing on climate change from an energy perspective and explains the naturally balanced energy transfer from the sun to the earth and society’s consumption of this energy. This book is for anyone worried about environmental damage from our reliance on fossil fuels and the global fight against climate change. The key message being we do not have to accept the inevitable and can work to prevent the worst.
Sun in a Bottle
by Charles SeifeWhen weapons builders detonated the first hydrogen bomb in 1952, they tapped into the biggest source of energy in our solar system - the phenomenon that makes the sun shine. Nuclear fusion seems a virtually unlimited source of power, but it has been at the center of a tragic and comic pursuit that has left scores of scientists battered and disgraced. Like the eternal quest to build a perpetual motion machine, the dream of harnessing the energy of a miniature star is irresistible. Not only would a fusion energy device give the world endless electrical power, it would give power to its inventors - financial power, the power of fame, even military might. Right now the world's richest countries are spending billions of dollars trying to build a giant fusion reactor. Yet if history is any guide, the money will not bring the dream of fusion energy within reach. Indeed, the quest for fusion energy has been a failure, generation after generation. Fusion is at the heart of some of the biggest scientific scandals of all time, and Charles Seife traces its story from its beginning into the twenty-first century. Even after fusion scientists face defeat after defeat, they continue trying to put the sun in a bottle, hoping against hope that they will succeed where others have failed. The science of wishful thinking is as strong as ever, and this book is our key to understanding why.