- Table View
- List View
VFD Challenges for Shipboard Electrical Power System Design
by Mohammed IslamAn in-depth exploration of shipboard power generation and distribution system design that utilizes variable frequency drives The variable frequency drive (VFD) application is a proven technology for shore-based applications. However, shore-based VFDs often are unsuitable for shipboard applications because the power generation and distribution fundamentals are completely different. VFD Challenges for Shipboard Electrical Power System Design explores the problems presented by variable frequency drives as they are applied in shipboard power generation and distribution system design and offers solutions for meeting these challenges. VFDs with configurations such as six pulse drive, 12 pulse drive, 18 pulse drive, active front end, pulse width modulation and many others generate many different levels of harmonics. These harmonics are often much higher than the regulations allow. This book covers a range of techniques used to provide ships with efficient energy that minimizes mechanical and electrical stress. This important book: Offers a comparison of shipboard grounding and VFD grounding Contains an analysis of the VFD effect in terms of shipboard power quality Includes specific examples of Department of Transportation standards regarding VFDs Written for commercial and naval engineers designing ships and/or shipboard power systems, VFD Challenges for Shipboard Electrical Power System Design is a comprehensive resource that addresses the problems and solutions associated with shipboard applications of VFD.
VIP: Engineering Wizard (VIP #1)
by Denise Lewis PatrickGet ready to light up the world with Lewis Latimer in this exciting middle grade nonfiction biography. Perfect for fans of the Who Was and Little Leaders series, the books in the VIP series tell the true—and amazing—stories of some of history's greatest trailblazers. Meet the VERY IMPORTANT PEOPLE who changed the world! Lewis Latimer was one of the greatest inventors of his time. He was also an engineer who transformed the lightbulb at Thomas Edison’s company. And he was a gifted artist, too! Experience all the exciting moments in Lewis Latimer’s thrilling life in this exciting biography, packed with two-color illustrations and fun facts, like who invented the Super Soaker!Short and engaging chapters are interspersed with special lists and other information made to order to engage kids, whether they're already biography fans or "have to" write a report for school. Extras include a timeline, a bibliography, and a hall of fame of other successful African American inventors.The VIP series features inspiring adventures and fun facts about some of history's greatest trailblazers—smart, tough, persevering innovators who will inspire today's kids. Featuring underappreciated historical figures and groups, with a focus on leaders in science and technology, the nonfiction biographies in the VIP series are fun and engaging. Just looking at the cover will make kids want to learn more about these VIPs, and once they dive in they will zoom through stories that read like adventures.Each book in the VIP series allows your middle grader to experience all the exciting moments in some very important but lesser known lives. These biographies for kids age 9-12 include: VIP: Dr. Mae Jemison: Brave Rocketeer: Engineering Wizard; VIP: Mahalia Jackson: Freedom's Voice; and VIP: Lydia Darragh: Unexpected Spy.
VIP: Voting Visionary (VIP)
by Andrea J. LoneyGet ready to fight for what’s right with Stacey Abrams in this exciting middle grade nonfiction biography. Perfect for fans of the Who Was and Little Leaders series, the books in the VIP series tell the true—and amazing—stories of some of history's greatest trailblazers. Meet the VERY IMPORTANT PEOPLE who changed the world!Stacey Abrams is an activist who works for fair voting rights. She’s a lawyer, an author, and a Nobel Peace Prize nominee, too! Experience all the exciting moments in Stacey’s thrilling life in this exciting biography, packed with two-color illustrations and fun facts, like how the census helps everyone!Short and engaging chapters are interspersed with special lists and other information made to order to engage kids, whether they're already biography fans or "have to" write a report for school. Extras include a timeline, a bibliography, and a hall of fame of other successful African American organizers and leaders.The VIP series features inspiring adventures and fun facts about some of history's greatest trailblazers—smart, tough, persevering innovators who will inspire today's kids. Featuring underappreciated historical figures and groups, with a focus on leaders in science and technology, the nonfiction biographies in the VIP series are fun and engaging. Just looking at the cover will make kids want to learn more about these VIPs, and once they dive in they will zoom through stories that read like adventures.Each book in the VIP series allows your middle grader to experience all the exciting moments in some very important but lesser known lives. These biographies for kids age 9-12 include: VIP: Dr. Mae Jemison: Brave Rocketeer: Engineering Wizard; VIP: Mahalia Jackson: Freedom's Voice; and VIP: Lewis Latimer.
VISUALIZING CHEMISTRY: The Progress and Promise of Advanced Chemical Imaging
by National Research Council of the National AcademiesScientists and engineers have long relied on the power of imaging techniques to help see objects invisible to the naked eye, and thus, to advance scientific knowledge. These experts are constantly pushing the limits of technology in pursuit of chemical imaging&#8212the ability to visualize molecular structures and chemical composition in time and space as actual events unfold&#8212from the smallest dimension of a biological system to the widest expanse of a distant galaxy. Chemical imaging has a variety of applications for almost every facet of our daily lives, ranging from medical diagnosis and treatment to the study and design of material properties in new products. In addition to highlighting advances in chemical imaging that could have the greatest impact on critical problems in science and technology, Visualizing Chemistry reviews the current state of chemical imaging technology, identifies promising future developments and their applications, and suggests a research and educational agenda to enable breakthrough improvements.
Va Mycorrhiza
by PowelThis book discusses VA Mycorrhizae fungi, its anatomy, morphology, and ecology, as well as its taxonomy. The isolation and culture of VA Mycorrhizal (VAM) fungi is also discussed. Other topics include; Mycorrhizae in plant growth, biological interactions with VA Mycorrhizal, the physiology of VA Mycorrhizal associations, inoculum production and field inoculation with VA Mycorrhizal fungi.
Vacation Guide to the Solar System: Science for the Savvy Space Traveler!
by Jana Grcevich Olivia KoskiPacked with real science and fueled by imagination, a beautifully illustrated guide to traveling in our solar systemImagine taking a hike along the windswept red plains of Mars to dig for signs of life, or touring one of Jupiter's sixty-four moons where you can photograph its swirling storms. For a shorter trip on a tight budget, the Moon is quite majestic and very quiet if you can make it during the off-season. Packed with full color illustrations and real-world science, Vacation Guide to the Solar System is the must-have planning guide for the curious space adventurer, covering all of the essentials for your next voyage, how to get there, and what to do when you arrive. Perfect for fans of Neil deGrasse Tyson's Astrophysics for People in a Hurry, this tongue-in-cheek reference guide is an imaginative exploration into the “What if” of space travel, sharing fascinating facts about space, the planets in our solar system, and even some moons!
Vacationscape: Developing Tourist Areas
by Clare A. GunnThe third edition of this classic volume integrates the idea of balancing tourism with protection of the resources upon which it depends. The text stresses the role of the community, identifies potential pitfalls, and raises issues of developmental ethics. It includes topics such as environmental impact, sustainability, and ecotourism. Special emphasis is given to the growing need for business to implement environmental protection and ecological integrity as an essential part of economic development. The book is filled with many sketches, functional diagrams, and photographs.
Vaccinated: From Cowpox to mRNA, the Remarkable Story of Vaccines
by Paul A. Offit M.D.Vaccines save millions of lives every year, and one man, Maurice Hilleman, was responsible for nine of the big fourteen. Paul Offit recounts his story and the story of vaccines Maurice Hilleman discovered nine vaccines that practically every child gets, rendering formerly dread diseases—including often devastating ones such as mumps and rubella—practically forgotten. Paul A. Offit, a vaccine researcher himself, befriended Hilleman and, during the great man’s last months, interviewed him extensively about his life and career. Offit makes an eloquent and compelling case for Hilleman’s importance, arguing that, like Jonas Salk, his name should be known to everyone. But Vaccinated is also enriched and enlivened by a look at vaccines in the context of modern medical science and history, ranging across the globe and throughout time to take in a fascinating cast of hundreds, providing a vital contribution to the continuing debate over the value of vaccines.
Vaccinated: The history and science of immunisation
by Sarah RidleyIn the wake of Covid-19, this book is a great first introduction as to what vaccines are, how scientists first developed them, information about the Covid-19 vaccination race, and other serious illnesses including malaria. The book includes the science behind germs and the immune system, the first inoculations performed in China using smallpox scabs, details of the early adopters of inoculation such as Lady Montagu in Europe and Cotton Mather in the USA, leading to Edward Jenner and the creation of the first vaccine.As well as the history of vaccines, the book looks at the modern science and issues around vaccines, covering topics, such as how you vaccinate the world, herd immunity, vaccine hesitancy and anti-vaxxers. The text is illustrated with archive and modern photography.
Vaccination Against Smallpox
by Edward JennerIn the three treatises contained in this volume, originally published between 1798 and 1800, Jenner, who was a pioneer in demonstrating that vaccination was an effective means of preventing smallpox, summarizes his evidence in favor of vaccination and describes individual cases.
Vaccination Investigation: The History and Science of Vaccines
by Tara HaelleVaccines are biological substances that cause the human immune system to build up its defenses against specific diseases. Public health officials recommend a series of vaccines for all children, as well as some vaccines for teenagers and adults. But not everyone gets the vaccines they need. Many poor nations don't have the resources to deliver vaccines to every community. Some parents refuse to have their children vaccinated because they don't believe the evidence proving that vaccines are safe. The effort to wipe out diseases using vaccines continues. Vaccine Investigation recounts the fascinating history of vaccines, their important role in protecting community health, and the excitement of cutting-edge research.
Vaccination in America: Medical Science and Children’s Welfare (Palgrave Studies in the History of Science and Technology)
by Richard J. AltenbaughThe success of the polio vaccine was a remarkable breakthrough for medical science, effectively eradicating a dreaded childhood disease. It was also the largest medical experiment to use American schoolchildren. Richard J. Altenbaugh examines an uneasy conundrum in the history of vaccination: even as vaccines greatly mitigate the harm that infectious disease causes children, the process of developing these vaccines put children at great risk as research subjects. In the first half of the twentieth century, in the face of widespread resistance to vaccines, public health officials gradually medicalized American culture through mass media, public health campaigns, and the public education system. Schools supplied tens of thousands of young human subjects to researchers, school buildings became the main dispensaries of the polio antigen, and the mass immunization campaign that followed changed American public health policy in profound ways. Tapping links between bioethics, education, public health, and medical research, this book raises fundamental questions about child welfare and the tension between private and public responsibility that still fuel anxieties around vaccination today.
Vaccine A: The Covert Government Experiment That's Killing Our Soldiers -- and Why GI's Are Only the First Victims
by Gary MatsumotoIn this provocative look at the US military from the Persian Gulf War through the 2003 invasion of Iraq, investigative journalist Gary Matsumoto contends that an anthrax vaccine dispensed by the Department of Defense was the cause of Gulf War Syndrome and the origins of a massive cover-up. Matsumoto calls it the worst friendly-fire incident in military history. A skillfully-woven narrative that serves as a warning about this man-made epidemic, Vaccine A is a much needed account of just what went wrong, and why.
Vaccine Delivery Technology: Methods and Protocols (Methods in Molecular Biology #2183)
by Andrew Hill Blaine A. PfeiferThis volume discusses the vaccine development process and the role delivery concepts contribute to a global goal of effective health outcomes. The chapters in this book cover a wide range of topics such as antigen discovery methods; genetic and protein antigen preparation; preparation of viral vaccines as VLPs; viral and non-viral gene delivery; needle-less or non-invasive delivery technology; vaccine storage; and vaccine administration and assessment. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics; lists of the necessary materials and reagents; step-by-step, readily reproducible laboratory protocols; and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and practical, Vaccine Delivery Technology: Methods and Protocols is a valuable resource for both novice and expert researchers, in and outside the field, who would like to gain insight into the impactful field of vaccines. Chapter 7 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Vaccine Design: Methods and Protocols, Volume 1. Vaccines for Human Diseases (Methods in Molecular Biology #2410)
by Sunil ThomasThis volume provides a practical guide providing step-by-step protocol to design and develop vaccines for human diseases. Divided into three volumes, Volume 1: Vaccines for Human Diseases guides readers through an introductory section on future challenges for vaccinologists and the immunological mechanism of vaccines. Chapters focus on design of human vaccines for viral, bacterial, fungal, and parasitic diseases as well as tumor vaccines. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and practical, Vaccine Design: Methods and Protocols, Second Edition, Volume 1: Vaccines for Human Diseases aims to be a useful practical guide to researchers to help further their study in this field.
Vaccine Design: Methods and Protocols, Volume 2. Vaccines for Veterinary Diseases (Methods in Molecular Biology #2411)
by Sunil ThomasThis volume provides a practical guide providing step-by-step protocol to explore vaccines for farm and companion animals, as well as for fish and insects. Divided into three volumes, Volume 2: Vaccines for Veterinary Diseases guides readers through veterinary vaccines, vaccines for poultry, vaccines for farm animals, and vaccines for veterinary parasites. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and practical, Vaccine Design: Methods and Protocols, Second Edition, Volume 2: Vaccines for Veterinary Diseases aims to be a useful practical guide to researchers to help further their study in this field.
Vaccine Design: Methods and Protocols, Volume 3. Resources for Vaccine Development (Methods in Molecular Biology #2412)
by Sunil ThomasThis volume provides a practical guide providing step-by-step methods and protocols on vaccine development and production. Divided into three volumes, Volume 3: Resources for Vaccine Development guides readers through chapters on vaccine adjuvants, vaccine vectors, production, vaccine delivery systems, vaccine bioinformatics, vaccine regulation, and intellectual property. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and practical, Vaccine Design: Methods and Protocols, Second Edition, Volume 3: Resources for Vaccine Development aims to be a useful practical guide to researchers to help further their study in this field.
Vaccine Development and Manufacturing
by Narahari S. Pujar Ronald Ellis Emily P. WenVaccine Manufacturing and Production is an invaluable reference on how to produce a vaccine - from beginning to end - addressing all classes of vaccines from a processing, production, and regulatory viewpoint. It will provide comprehensive information on the various fields involved in the production of vaccines, from fermentation, purification, formulation, to regulatory filing and facility designs. In recent years, there have been tremendous advances in all aspects of vaccine manufacturing. Improved technology and growth media have been developed for the production of cell culture with high cell density or fermentation. Vaccine Manufacturing and Production will serve as a reference on all aspects of vaccine production by providing an in-depth description of the available technologies for making different types of vaccines and the current thinking in facility designs and supply issues. This book will provide insight to the issues scientists face when producing a vaccine, the steps that are involved, and will serve as a reference tool regarding state-of-the-art vaccine manufacturing technologies and facility set-up.Highlights include:Comprehensive coverage of vaccine production : from a process point of view- fermentation to purification to formulation developments; from a production point of view - from facility design to manufacturing; and from a regulatory point of view - requirements from government agenciesAuthors from different major pharmaceutical and biotechnology companiesDescribes the challenges and issues involved in vaccine production and manufacturing of the different classes of vaccines, an area not covered by other books currently on the market
Vaccine Efficacy Evaluation: The Gnotobiotic Pig Model (Pocket Guides to Biomedical Sciences)
by Lijuan YuanTesting the immunogenicity, protective efficacy and safety in animal models is a crucial step in vaccine development. Pigs raised in germ-free environments, called gnotobiotic (Gn) pigs, are one of the most useful animal models for testing vaccines. The Gn pig model is a widely accepted model for studying pathogenesis and immunity and an ideal model for pre-clinical testing for the safety and efficacy of enteric viral vaccines. Through these studies and others, the Gn pig model has been established as the most reliable animal model for pre-clinical evaluation of human rotavirus and norovirus vaccines. This book provides detailed information on establishing Gn pig models, determining a proper virus inoculum pool and challenge dose, measuring protection and calculating efficacy, and delineating intestinal and systemic immune responses associated with the protection.Key Features Provides a natural history of human rotavirus and norovirus infection in Gn pigs Establishes the optimal virus challenge doses in Gn pigs for vaccine evaluation Evaluates various candidate rotavirus and norovirus vaccines Discusses human gut microbiota transplanted Gn pig models Documents the role of probiotics and rice bran as prophylactics and vaccine adjuvants
Vaccine Protocols
by Andrew P. Robinson Christopher N. Wiblin Graham H. FarrarExpert practitioners present a comprehensive approach to vaccine development, production, and assessment that can be adapted successfully to any vaccine. Their approach not only includes state-of-the-art techniques for developing live viral and bacterial vectors, expressing foreign vaccine antigens, and producing peptide and conjugate vaccines, but also offers advice and guidance on clinical trials and regulatory requirements. Additional techniques describe such powerful tools as the use of adjuvants, freeze drying vaccines, microencapsulation of vaccines, the full assessment of immunogenicity and potency of vaccines in animal models, and the creation of DNA vaccines, chimeric proteins, and recombinant toxoids.
Vaccine Technologies for Veterinary Viral Diseases: Methods and Protocols (Methods in Molecular Biology #2465)
by Alejandro BrunThis second edition includes a collection of antigen production and delivery strategies for vaccine development in veterinary species. New and updated chapters guide readers through protocols for antigen production, experimental antigen delivery and the analysis of immune responses upon vaccination. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Vaccine Technologies for Veterinary Viral Diseases: Methods and Protocols, Second Edition aims to be a useful and practical guide to researches to help further their study in this field.
Vaccines and Autoimmunity
by Yehuda Shoenfeld Nancy Agmon-Levin Lucija TomljenovicIn light of the discovery of Autoimmune Syndrome Induced by Adjuvants, or ASIA, Vaccines and Autoimmunity explores the role of adjuvants - specifically aluminum in different vaccines - and how they can induce diverse autoimmune clinical manifestations in genetically prone individuals. Vaccines and Autoimmunity is divided into three sections; the first contextualizes the role of adjuvants in the framework of autoimmunity, covering the mechanism of action of adjuvants, experimental models of adjuvant induced autoimmune diseases, infections as adjuvants, the Gulf War Syndrome, sick-building syndrome (SBS), safe vaccines, toll-like receptors, TLRS in vaccines, pesticides as adjuvants, oil as adjuvant, mercury, aluminum and autoimmunity. The following section reviews literature on vaccines that have induced autoimmune conditions such as MMR and HBV, among others. The final section covers diseases in which vaccines were known to be the solicitor - for instance, systemic lupus erythematosus - and whether it can be induced by vaccines for MMR, HBV, HCV, and others. Edited by leaders in the field, Vaccines and Autoimmunity is an invaluable resource for advanced students and researchers working in pathogenic and epidemiological studies.
Vaccines for Neglected Pathogens: Focus on Leprosy, Leishmaniasis, Melioidosis and Tuberculosis
by Myron ChristodoulidesThis book reviews successes and (remaining) challenges in vaccine development for the selected Neglected Tropical Diseases (NTD) of Leprosy, Leishmaniasis, Meliodoisis and Tuberculosis, which are a continuous burden for millions of people in affected areas worldwide. Written by frontline researchers, the volume deep-dives into different vaccine strategies, provides biotechnological background information and also tackles animal models in NTD therapeutics research. By bringing together state-of-the-art expert knowledge, the book contributes to the aim of ultimately ending the epidemics of neglected tropical diseases, complying with UN Sustainable Development Goal 3, Health and Well-Being.The volume highlights the activities of the research network VALIDATE (VAccine deveLopment for complex Intracellular neglecteD pAThogEns), funded by the Medical Research Council in the UK. The four NTDs discussed in the book were selected as these are in the focus of VALIDATE’s research.The book targets scientists and clinicians working on NTDs, as well as all readers with a background in biomedicine and interest in vaccine development.This is an open access book.
Vaccines, Medicines and COVID-19: How Can WHO Be Given a Stronger Voice? (SpringerBriefs in Public Health)
by Germán VelásquezThis open access book is a collection of research papers on COVID-19 by Germán Velásquez from 2020 and early 2021 that help to answer the question: How can an agency like the World Health Organization (WHO) be given a stronger voice to exercise authority and leadership? The considerable health, economic and social challenges that the world faced at the beginning of 2020 with COVID-19 continued and worsened in many parts of the world in the second-half of 2020 and into 2021. Many of these countries and nations wanted to explore COVID-19 on their own, sometimes without listening to the main international health bodies such as WHO, an agency of the United Nations system with long-standing experience and vast knowledge at the global level and of which all countries in the world are members. In this single volume, the chapters present the progress of thinking and debate — particularly in relation to drugs and vaccines — that would enable a response to the COVID-19 pandemic or to subsequent crises that may arise. Among the topics covered:COVID-19 Vaccines: Between Ethics, Health and EconomicsMedicines and Intellectual Property: 10 Years of the WHO Global StrategyRe-thinking Global and Local Manufacturing of Medical Products After COVID-19Rethinking R&D for Pharmaceutical Products After the Novel Coronavirus COVID-19 ShockIntellectual Property and Access to Medicines and VaccinesThe World Health Organization Reforms in the Time of COVID-19Vaccines, Medicines and COVID-19: How Can WHO Be Given a Stronger Voice? is essential reading for negotiators from the 194 member countries of the World Health Organization (WHO); World Trade Organization (WTO) and World Intellectual Property Organization (WIPO) staff participating in these negotiations; academics and students of public health, medicine, health sciences, law, sociology and political science; and intergovernmental organizations and non-governmental organizations that follow the issue of access to treatments and vaccines for COVID-19.
Vaccines: A Biography
by Andrew W. ArtensteinThe History and Biography of Vaccines against Infectious Diseases is a multi-authored book, written for an academic audience but accessible to a general readership as well. The book examines the human stories that underlie the development of vaccines against infectious diseases. Each chapter traces the lineage of a vaccine by examining the people behind the scientific hypotheses and discoveries that led to vaccine breakthroughs. These stories are firmly anchored in their historical context, as the "biography" of a vaccine generally has its origins in a medical problem rooted within a social context that subsequently engages scientists and enlists others in the eventual solution. A prominent theme woven throughout the book is the interdependence of incremental scientific advances and investigators on one another and how such advances ultimately led to practical, preventive solutions to major public health problems in society. Additionally, the human aspect of various pivotal events in the histories of specific vaccines are illustrated--this includes scientific and political hurdles and details of clinical trial controversies. In this fashion the work interweaves scientific themes, personal stories of those involved, and the sociohistorical context in which they worked in a manner that illustrates their inter-relatedness and provides the reader with exciting accounts of these advances.