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Madness and Memory: The Discovery of Prions—A New Biological Principle of Disease
by Stanley B. PrusinerIn this &“utterly fascinating&” science memoir, the Nobel Prize–winning author chronicles his revolutionary discovery of a major cause of brain diseases (The New York Times). In 1997, Stanley B. Prusiner received the Nobel Prize in Physiology or Medicine for his research on devastating brain diseases. That he was the award&’s sole recipient was entirely appropriate. His struggle to identify the agent responsible for scrapie and mad cow disease in animals, and Creutzfeldt-Jakob disease in humans, had been waged largely alone, and in some cases, in the face of strenuous opposition. In Madness and Memory, Prusiner recounts the journey to his remarkable discovery of prions—infectious proteins that replicate and cause disease, but surprisingly contain no genetic material. Along the way, he sheds light on the world of contemporary science and the meticulousness and perseverance it requires. Through his telling, the agony and triumph of years of research comes to life, along with fascinating portraits of fellow scientists racing to make breakthrough discoveries. Prusiner&’s hypothesis, once considered heresy, now stands as accepted science and provides a path toward conquering such pervasive scourges as Alzheimer&’s, Parkinson&’s, Lou Gehrig&’s, and others diseases. &“Madness and Memory is the story of one of the most important discoveries in recent medical history, and it is also a vivid and compelling portrait of a life in science.&” —Oliver Sacks, MD, neurologist and author of Hallucinations
The Madness of Captain Cyclops (Kid Squad Saves The World)
by John PerritanoWhen the testing of a nuclear-powered invisibility device goes awry, Captain Rudolph Von Dorn is transformed into the evil Captain Cyclops, blowing up ships and islands at will—and the Kid Squad, with the help of Von Dorn’s daughter Jenny, is called upon to reverse the effects of the accident and save the world.
Magic Circles
by Lana ParkerDid you ever think about how many things in your life would vanish if there were no wheels?
The Magic Fan
by Keith BakerGuided by a magic fan, Yoshi builds a boat to catch the moon, a kite to reach the clouds, and a bridge that saves the villagers from a tidal wave.
Magic Noodles
by Tracy Vonder BrinkOn a chilly day in 1947, a Japanese inventor named Momofuku Ando observed people waiting out in the cold for a hot meal. He dreamed of bringing fast-cooking noodles to the whole world. And he did—with ramen noodles! Sometimes the simplest inventions are the best!
The Magic of Ceramics
by David W. RichersonMost people would be surprised at how ceramics are used, from creating cellular phones, radio, television, and lasers to its role in medicine for cancer treatments and restoring hearing. The Magic of Ceramics introduces the nontechnical reader to the many exciting applications of ceramics, describing how ceramic material functions, while teaching key scientific concepts like atomic structure, color, and the electromagnetic spectrum. With many illustrations from corporations on the ways in which ceramics make advanced products possible, the Second Edition also addresses the newest areas in ceramics, such as nanotechnology.
The Magic Ring: Systems Thinking Approach to Control Systems (Contemporary Systems Thinking)
by Piero MellaThis book presents a new understanding on how control systems truly operate, and explains how to recognize, simulate, and improve control systems in all fields of activity. It also reveals the pervasive, ubiquitous and indispensable role of control processes in our life and the need to develop a “control-oriented thinking”—based on uncomplicated but effective models derived from systems thinking—that is, a true “discipline of control.” Over the book’s thirteen chapters, Piero Mella shows that there are simple control systems (rather than complex ones) that can easily help us to manage complexity without drawing upon more sophisticated control systems. It begins by reviewing the basic language of systems thinking and the models it allows users to create. It then introduces the control process, presenting the theoretical structure of three simple control systems we all can observe in order to gain fundamental knowledge from them about the basic structure of a control system. Then, it presents the anatomy of the simplest “magic ring” and the general theoretical model of any control system. This is followed by an introduction to a general typology of control systems and a broader view of control systems by investigating multi-lever control systems and multi-objective systems. The book undertakes the concepts through various environments, increasingly broader in scope to suggest to readers how to recognize therein control systems manifestations in everyday life and in natural phenomena. Updated for the 2nd edition, new chapters explore control systems regulating the biological environment and the organizations, with an in-depth study of the control of quality, productivity, production, stocks and costs. Finally, it concludes by dealing with the learning process, problem-solving, and designing the logical structure of control systems.
The Magic School Bus: Looking For Liz
by Joanna ColeThe class takes the magic school bus to various animal habitats.
The Magic School Bus and the Electric Field Trip
by Joanna ColeSmall enough to squeeze through power lines, Ms. Frizzle's class learns how electric current travels through the town, lights up a light bulb, heats up a toaster, and runs an electric motor. Fans of the Magic School Bus won't be left behind by this simple and informative introduction to the generation and distribution of electricity. This book has picture descriptions.Also please note: where the book has two dashes instead of an em dash, I left two dashes; where the book has an em dash, I made an em dash.
The Magic School Bus Explores the Senses (The Magic School Bus)
by Joanna ColeTo celebrate its 20th anniversary, Scholastic is re-releasing the ten original Magic School Bus titles in paperback. With updated scientific information, the bestselling science series ever is back!On a most sense-sational trip that takes them through an eye, an ear, a tongue, and even a dog's nose, Ms. Frizzle's class learns about the senses. Using their trademark sense of humor, Joanna Cole and Bruce Degen provide facts about the senses in both the human and animal worlds.
Magic, Science, and Religion in Early Modern Europe (New Approaches to the History of Science and Medicine)
by Mark A. WaddellFrom the recovery of ancient ritual magic at the height of the Renaissance to the ignominious demise of alchemy at the dawn of the Enlightenment, Mark A. Waddell explores the rich and complex ways that premodern people made sense of their world. He describes a time when witches flew through the dark of night to feast on the flesh of unbaptized infants, magicians conversed with angels or struck pacts with demons, and astrologers cast the horoscopes of royalty. Ground-breaking discoveries changed the way that people understood the universe while, in laboratories and coffee houses, philosophers discussed how to reconcile the scientific method with the veneration of God. This engaging, illustrated new study introduces readers to the vibrant history behind the emergence of the modern world.
Magmatism and Geodynamics: Terrestrail Magmatism Throughout the Earth's History
by O. A. BogatikovMagnatism is the only true endogenic process for generating new material on the Earth's surface. Obviously, magmatism and tectonic movements are reflections of geodynamics, that is, physical processes which occur in deep-seated environments. What are the interrelationships between magmatism and tectronics? How did the character of terrestrial magmatism change through time and are there any irregularities in this process?
Magnesium: Applications in Clinical Medicine
by Erine A. Kupetsky D. O.Magnesium is an essential mineral required by humans, playing an important role in multiple biochemical processes as well as preventing and managing several diseases and disorders. Deficiencies of magnesium can lead to a wide range of medical conditions, including cardiovascular disease, diabetes, and hypertension. <P><P>With myocardial infarction and stroke being the first and fifth cause of mortality in the United States, the pharmaceutical industry has been trying to produce therapies that reduce co-morbidity and mortality. Recent observational studies of magnesium have added to the list of potential therapeutic modalities that have been proven useful in reducing hypertension, stroke sequalae, metabolic syndrome/dyslipidemia, and inflammatory diseases. Magnesium therapeutic modalities also have impacts in the fields of neurology, the elderly, and in obstetrics. <P><P>Magnesium: Applications in Clinical Medicine explores the many uses of magnesium and its applications in clinical medicine. <P><P>Features: <li>Presents information on the impacts magnesium has on various aspects of health conditions and disease prevention. <li>Describes magnesium usage in treating and managing several conditions including dyslipidemia, migraine, metabolic syndrome, and high blood pressure. <li>Discusses magnesium therapy in stroke and magnesium deficiency in attention deficit hyperactivity disorder. <li>Promotes knowledge of overall health and wellness that can be applied in any specialty of medicine. <P><P>This book encompasses various uses of magnesium in a clinical setting ranging from its role in maintaining homeostasis, to its uses in the fields of dermatology, cardiology, neurology, and in obstetrics. Written by contributors who are experts in their fields, it is a comprehensive collaboration of this ubiquitous dietary supplement’s applications in clinical medicine.
Magnesium 2021: Proceedings of the 12th International Conference on Magnesium Alloys and Their Applications (The Minerals, Metals & Materials Series)
by Bruce Williams John Allison Warren Poole Alan Luo Eric Nyberg Sean Agnew Mihriban Pekguleryuz Karl Kainer Kumar Sadayappan Steve YueThis collection from the 12th International Conference on Magnesium Alloys and Their Applications (Mg 2021)—the longest running conference dedicated to the development of magnesium alloys—covers the breadth of magnesium research and development, from primary production to applications to end-of-life management. Authors from academia, government, and industry discuss new developments in magnesium alloys and share valuable insights. Topics in this volume include but are not limited to the following: Primary production Alloy development Solidification and casting processes Forming and thermo-mechanical processing Other manufacturing process development (including joining and additive manufacturing) Corrosion and protection Modeling and simulation Structural, functional, biomedical, and energy applicationsAdvanced characterization and fundamental theoriesRecycling and environmental issues
Magnesium Alloys as Degradable Biomaterials
by Yufeng ZhengMagnesium Alloys as Degradable Biomaterials provides a comprehensive review of the biomedical applications of biodegradable magnesium and its alloys. Magnesium has seen increasing use in orthopedic and cardiovascular applications over the last decade, particularly for coronary stents and bone implants.The book discusses the basic concepts of biodeg
Magnesium Alloys for Biomedical Applications: Advances and Challenges
by Deepak Kumar Nooruddin AnsariMagnesium alloys have enormous potential for use in biomedical implants. Magnesium Alloys for Biomedical Applications delves into recent advances and prospects for implementation and provides scientific insights into current issues posed by Mg alloy materials. It provides an overview of research on their mechanical and tribological characteristics, corrosion tendencies, and biological characteristics, with a particular emphasis on biomedical implants. Details the fundamentals of Mg alloys as well as necessary surface modifications of Mg alloys for biomedical use. Discusses emerging Mg alloys and their composites. Covers mechanical, tribological, and chemical properties, as well as fatigue and corrosion. Highlights emerging manufacturing methods and advancements in new alloy design, composite manufacturing, unique structure design, surface modification, and recyclability. Helps readers identify appropriate Mg-based materials for their applications and select optimal improvement methods. Summarizes current challenges and suggests a roadmap for future research. Aimed at researchers in materials and biomedical engineering, this book explores the many breakthroughs achieved with these materials and where the field should concentrate to ensure the development of safe and reliable Mg alloy-based implants.
Magnesium and Its Alloys: Technology and Applications (Metals And Alloys Ser.)
by Leszek A. Dobrzański, George E. Totten and Menachem BambergerMagnesium and Its Alloys: Technology and Applications covers a wide scope of topics related to magnesium science and engineering, from manufacturing and production to finishing and applications. This handbook contains thirteen chapters, each contributed by experts in their respective fields, and presents a broad spectrum of new information on pure magnesium, magnesium alloys, and magnesium matrix MgMCs composites. It covers such topics as computational thermodynamics, modern Mg-alloys with enhanced creep or fatigue properties, cutting-edge approaches to melt treating (grain refinement, micro-alloying, and the resulting solidification and growth), coatings, surface engineering, environmental protection (recycling and green energy storage and production), as well as biomedical applications. Aimed at researchers, professionals, and graduate students, the book conveys comprehensive and cutting-edge knowledge on magnesium alloys. It is especially useful to those in the fields of materials engineering, mechanical engineering, manufacturing engineering, and metallurgy.
Magnesium and Its Alloys as Implant Materials: Corrosion, Mechanical and Biological Performances
by Mirco Peron Filippo Berto Jan TorgersenDespite their tremendous potential, Mg and its alloys are not yet used in biomedical applications. This book aims to provide scientific insights into the challenges of the materials, and give an overview of the research regarding their mechanical properties, corrosion behaviour and biological performances. The authors intend to put the reader into the position to accurate discern the proper Mg-based material for his/her applications and to choose the proper improvement strategy to his/her cause. To this aim, the manuscript is structured as follow: in Section 2, the main challenges hampering the use of magnesium in biomedical applications and the common improvement strategies are listed. In Section 3, the most investigated Mg alloys are reported in separate sub-sections, detailing their mechanical properties, corrosion behaviour and biotoxicity. High-pure and ultra-high-pure Mg, Al-based Mg alloys, Zn-based Mg alloys, Ca-based alloys and RE-based Mg alloys have been considered. In Section 4, the alloys’ performances with respect to the challenges is summarized providing the reader with useful information and suggestions on the potentially most suited choice. Finally, in Section 5, an outlook portraying the authors’ opinion of the future development of the field will be provided. This book will allow biomedical engineers, surface scientists, material scientists, implant manufacturers and companies working on implant approval an overview of the state-of-the-art technologies adopted so far to overcome the drawbacks of Mg for biomedical applications. Particular emphasis is put on explaining the link between mechanical, corrosion and biocompatible properties of Mg and its alloys as well as their pros and cons. In doing so, the authors intend to put the reader into the position to accurate discern the proper Mg-based material for his/her applications and to choose the proper improvement strategy to his/her cause.
Magnesium-Based Energy Storage Materials and Systems
by Jianxin Zou Yanna NuLi Zhigang Hu Xi Lin Qiuyu ZhangUnderstand the energy storage technologies of the future with this groundbreaking guide Magnesium-based materials have revolutionary potential within the field of clean and renewable energy. Their suitability to act as battery and hydrogen storage materials has placed them at the forefront of the world#s most significant research and technological initiatives. It has never been more essential that professionals working in energy storage and energy systems understand these materials and their extraordinary potential applications. Magnesium-Based Energy Storage Materials and Systems provides a thorough introduction to advanced Magnesium (Mg)-based materials, including both Mg-based hydrogen storage and Mg-based batteries. Offering both foundational knowledge and practical applications, including step-by-step device design processes, it also highlights interactions between Mg-based and other materials. The result is an indispensable guide to a groundbreaking set of renewable energy resources. Magnesium-Based Energy Storage Materials and Systems readers will also find: In-depth analysis of the effects of employing catalysts, nano-structuring Magnesium-based materials, and many more subjects Detailed discussion of electrolyte, cathode, and anode materials for Magnesium batteries Snapshots of in-progress areas of research and development Magnesium-Based Energy Storage Materials and Systems is ideal for materials scientists, inorganic chemists, solid state chemists, electrochemists, and chemical engineers.
Magnesium Biomaterials
by Nicholas Travis Kirkland Nick BirbilisMagnesium Biomaterials provides a succinct up-to-date overview of Magnesium biomaterial development, critically examines the types of in vitro experiments that may be performed, and investigates the numerous variables that affect Magnesium biodegradation when undertaking these experiments. This work also discusses the direction in which current Magnesium biomaterial development is heading and the necessary steps for future development of this field. Information is drawn from numerous multi-disciplinary sources to provide a coherent and critical overview. Magnesium Biomaterials is ideal for researchers in the area of bio-Mg, companies interested in exploring their own alloys, and for researchers working with other biodegradable materials who are seeking a cross-platform understanding of material performance.
Magnesium: From Resources To Production
by Hussein K. Abdel-AalMagnesium is one of the most abundant minerals in seawater. Extracting magnesium from seawater could reduce cost of this mineral, resulting in positive implications for industries that use it. This book addresses mineral process engineering with emphasis on magnesium and provides practicing engineers and students with comprehensive knowledge on magnesium and how it is extracted from seawater and magnesium ores. It takes a chemical engineering approach as separation of magnesium from seawater involves the application of the powerful science of chemistry and transport phenomena principles. This monograph discusses magnesium resources and occurrence, includes an exploration study on deriving magnesium and mineral salts from seawater, and features coverage of magnesium chloride. It also covers commercial methods for magnesium production as an end product, current and prospective applications in the energy domain, and offers an account of the use of magnesium to store hydrogen in the form of magnesium hydride.
Magnesium in Human Health and Disease
by Sherma Zibadi Victor R. Preedy Ronald Ross WatsonMagnesium is an essential mineral which is required for growth and survival of humans. Since magnesium is a mineral and not synthesizable it must be obtained through dietary foods and/or supplements. Magnesium in Human Health and Disease reviews the benefits of magnesium supplementation to reach recommended intakes as well as provides new research that suggests how reaching levels above the recommended intakes can promote health and treat various diseases. Magnesium deficiency can cause low serum potassium and calcium levels, retention of sodium, and low circulating levels of regulatory hormones. These changes in nutrients cause neurological and muscular symptoms such as tremor and muscle spasms. Further magnesium deficiency causes loss of appetite, nausea, vomiting, personality changes and death from heart failure. Causes of magnesium deficiency include alcohol abuse, poorly controlled diabetes, excessive or chronic vomiting and/or diarrhea. Thus the effects of inadequate and deficient intakes or levels of magnesium is critical to health and are reviewed by the expert clinicians in this book. Magnesium in Human Health and Disease provides the most current research to support the potential benefits or lack thereof for normal and high supplementation with magnesium. Animal model research and early human trials are reviewed to document other disease states such as hypertension, cholesterol level, type 2 diabetes and cardiovascular disease that would benefit from increased magnesium.
Magnesium, Magnesium Alloys, and Magnesium Composites: Processing, Mechanical And Corrosion Characteristics (Springerbriefs In Materials Ser.)
by Manoj Gupta Sharon Nai Mui LingA look at the current and future uses of magnesium-based products and their role in the world's environmental and technological revolution The lightest of all structural metals, having one-fourth the density of steel and two-thirds that of aluminum, magnesium has already been adopted as an alternative construction material in applications as far ranging as automotive and sports equipment, electronics, and space technology. In a world concerned with minimizing the environmental impact of products, the choice of light-weight, energy-saving, and high-performance materials, like magnesium, would seem a small, significant step towards improving life on this planet. Magnesium, Magnesium Alloys, and Magnesium Composites introduces the science and current applications of this important metal, shedding light on the magnesium-based composites developed over the last fifteen years. Chapters include in-depth discussion of: The characteristics of pure magnesium—including atomic properties and crystal structure as well as physical, electrical, and mechanical properties Magnesium alloys—and the effects of the alloying elements, such as aluminum, lithium, copper, nickel, and silicon The properties of magnesium-based composites—and the effects of different types (metallic, ceramic, interconnected, and intermetallic) of reinforcements of varying length (from micron scale to nanometric length) Corrosion aspects of magnesium-based materials Magnesium-based products in medicine, sports equipment, and the automotive, aerospace, and electronics industries Bringing together, for the first time, the science, properties, and technologies relating to the current and future uses of magnesium, this important reference also offers readers a glimpse of a not-too-distant world in which environmental safety and sound engineering are a reality.
Magnesium Technology 2000
by Byron B. Clow Howard I. Kaplan John N. HrynThese proceedings provide an overview of magnesium production technology, mechanical properties, corrosion resistance, and alloy development. Co-sponsored with TMS by the Magnesium Association, the symposium was divided into several sessions: Electrolytic technology, thermal reduction/environmental, automotive issues and recycling, alloy development/corrosion, solidification, creep properties/heat treating effects, physical/mechanical properties, wrought alloys/thixmolding.A collection of papers from the 2000 TMS Annual Meeting & Exhibition, held in Nashville, Tennessee, March 12-March 15, 2000.
Magnesium Technology 2001
by John N. HrynPapers presented at the Proceedings of the symposium jointly sponsored by the Magnesium Committee and Reactive Metals Committee of the TMS Light Metals Division (LMD), the International Magnesium Association, and the Corrosion and Environmental Effects Committee, a joint committee of the TMS Structural Materials Division (SMD) and the ASM International Materials Science Critical Technology Sector, held during the 2001 TMS Annual Meeting in New Orleans, Louisiana, U.S.A, February 11-15, 2001.