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The author tells of growing up with her sister who has diabetes and then later her own journey with diabetes.
This new and 18th edition attempts to provide the essential information that practitioners, house staff, medical students, and other care providers involved in pediatric health care need to understand to effectively address the enormous range of biologic, psychologic, and social problems that our children and youth may face. Topics covered include genetics, endocrinology, etiology, epidemiology, pathology, pathophysiology, treatment, and prognosis.
Written by practising physicians specializing in pediatric hematology, neonatology, immunology, pediatric infectious disease and transfusion medicine, this is a practical guide to the pathogenesis, recognition and management of hematologic problems in the neonate. The focus is on clinical issues encountered by pediatric specialists, and there are chapters devoted to disorders of leukocytes, platelets, procoagulant and anticoagulant proteins, and disorders of red blood cells. Neonatal transfusion, malignant disorders in the newborn, neonatal hemoglobinopathy screening, harvesting and storage of umbilical cord stem cells are also covered, and practical approaches to diagnosis and treatment given.
Worldwide more than one million babies die annually from perinatal asphyxia and its associated complications such as neonatal encephalopathy - one of the major causes of cerebral palsy and cognitive deficiencies in children aside from prematurity. Cooling the head - or the entire body - minimizes neuronal death, enabling the neonatal brain to be 'rescued' thus greatly improving developmental outcomes. Hypothermic neural rescue therapy has revolutionized the treatment of this condition and is a major recent achievement in neonatal medicine. This landmark book provides a brief scientific underpinning of hypothermic neural rescue therapy and lays out the evidence base for good practice. Internationally recognized authorities give practical advice, drawn from personal experience, on how to deliver hypothermia in the neonatal intensive care unit. A valuable addition to any neonatal unit, this is essential reading for neonatologists, neonatal nurses and paediatric neurologists.
Are you socially awkward? Technologically sophisticated or just 1 extremely passionate about one or more subjects? Well, maybe you're a "nerd." And what's wrong with being a nerd? In this fascinating book, child and family psychologist David Anderegg examines the process by which kids learn what nerds are, and what happens to their identities as a result of their developing awareness of this uniquely American stereotype. In Nerds, Anderegg surveys the long history of American anti-intellectualism and its current avatar: antinerd sentiment. Although at first glance it may not seem so bad to call someone a nerd, this stereotype is wreaking havoc in the lives of our children, affecting their performance in school and ultimately jeopardizing American economic competitiveness. (It may not be an accident that international math and science testing shows American fifteen-year-olds in twenty-fourth place among the world's most developed countries.) Deftly revealing layers of cultural "knowledge" about nerds, Anderegg explores such topics as: * the conformity of adolescence and the endurance of adolescent stereotypes, long after people should know better * the pathologizing of nerds with diagnoses such as Asperger's syndrome O the archetypal struggles of nerds and jocks in popular culture and history . Using educational research, psychologic theory, and interviews with kids themselves, Anderegg urges readers to start deconstructing this most harmful of social constructions before any more smart and self-confident kids stop being so interested in what they're interested in In other words, before they stop being kids.
This book tells you how two friends did it, and how you can do it too. It's not a diet devised by some bossy string bean who has never been more than 7 pounds overweight, nor by a fat middle-aged doctor, but a real, long-term, workable diet for real people. A modified and therefore bearable low-carb, high-protein way of eating, the diet really works and includes meal plans, recipes, advice on clothes, make-up and hair at every stage from fat to thin. It doesn't include impossible exercise routines or disgusting things to eat. Above all, it gets to the bottom of why we overeat--and shows you how to stop. There's never been a diet book like it--for women, by women, with jokes and useful tips, and advice that is truly simple to follow. What other diet book tells you to pour yourself a large drink at the end of the day, because you've earned it?
Over the last decade, the study of complex networks has expanded across diverse scientific fields. Increasingly, science is concerned with the structure, behavior, and evolution of complex systems ranging from cells to ecosystems. Modern network approaches are beginning to reveal fundamental principles of brain architecture and function, and in Networks of the Brain, Olaf Sporns describes how the integrative nature of brain function can be illuminated from a complex network perspective. Highlighting the many emerging points of contact between neuroscience and network science, the book serves to introduce network theory to neuroscientists and neuroscience to those working on theoretical network models. Brain networks span the microscale of individual cells and synapses and the macroscale of cognitive systems and embodied cognition. Sporns emphasizes how networks connect levels of organization in the brain and how they link structure to function. In order to keep the book accessible and focused on the relevance to neuroscience of network approaches, he offers an informal and nonmathematical treatment of the subject. After describing the basic concepts of network theory and the fundamentals of brain connectivity, Sporns discusses how network approaches can reveal principles of brain architecture. He describes new links between network anatomy and function and investigates how networks shape complex brain dynamics and enable adaptive neural computation. The book documents the rapid pace of discovery and innovation while tracing the historical roots of the field. The study of brain connectivity has already opened new avenues of study in neuroscience. Networks of the Brain offers a synthesis of the sciences of complex networks and the brain that will be an essential foundation for future research.
The issues of mental causation, consciousness, and free will have vexed philosophers since Plato. In this book, Peter Tse examines these unresolved issues from a neuroscientific perspective. In contrast with philosophers who use logic rather than data to argue whether mental causation or consciousness can exist given unproven first assumptions, Tse proposes that we instead listen to what neurons have to say. Because the brain must already embody a solution to the mind--body problem, why not focus on how the brain actually realizes mental causation? Tse draws on exciting recent neuroscientific data concerning how informational causation is realized in physical causation at the level of NMDA receptors, synapses, dendrites, neurons, and neuronal circuits. He argues that a particular kind of strong free will and "downward" mental causation are realized in rapid synaptic plasticity. Recent neurophysiological breakthroughs reveal that neurons function as criterial assessors of their inputs, which then change the criteria that will make other neurons fire in the future. Such informational causation cannot change the physical basis of information realized in the present, but it can change the physical basis of information that may be realized in the immediate future. This gets around the standard argument against free will centered on the impossibility of self-causation. Tse explores the ways that mental causation and qualia might be realized in this kind of neuronal and associated information-processing architecture, and considers the psychological and philosophical implications of having such an architecture realized in our brains.
Thoroughly revised and updated to reflect key advances in behavioral neurology, Neurobehavioral Anatomy, Third Edition is a clinically based account of the neuroanatomy of human behavior centered on a consideration of behavioral dysfunction caused by disorders of the brain. A concise introduction to brain-behavior relationships that enhances patient care and assists medical students, the book also serves as a handy reference to researchers, neuroscientists, psychiatrists, and geriatricians. The book outlines how cognitive and emotional functions are represented and organized in the brain to produce the behaviors regarded as uniquely human. It reviews the effects of focal and diffuse brain lesions, and from this analysis a conception of the normal operations of the healthy brain emerges. Christopher M. Filley integrates data and material from different disciplines to create a concise and accessible synthesis that informs the clinical understanding of brain-behavior relationships. Clinically practical and theoretically stimulating, the book is an invaluable resource for those involved in the clinical care and study of people with neurobehavioral disorders. Including a useful glossary and extensive references guiding users to further research, the third edition will be of significance to medical students, residents, fellows, practicing physicians, and the general reader interested in neurology.
This book presents an overview of the latest theories of affect regulation and focuses on how these theories work in clinical settings and how therapists can be taught to implement them. The notion of teaching and learning will be extended by the theories themselves-the author presents methods of education that enact the theories being taught. The book is divided into eight chapters, each one highlighting a particular structure or related structures of the brain. Suggestions for learning how to clinically apply the neurobiological/neuroanatomical information are offered. What is so unique about this book is that the bulk of the chapters are clinical dialogue, accompanied by neurobiological commentary. Thus, readers can see for themselves, during the course of parts of sessions, just how a "neurobiological outlook" can inform therapeutic understandings of what clients are doing and saying. The result is a very user-friendly learning experience for readers, as they are taken along a journey of understanding various brain systems and how they relate to psychotherapeutic principles. Elegantly bridging the gap between the academic and clinical domains, this book is essential for anyone interested in the application of neurobiological principles to psychotherapy and wishes to learn about neurobiology without feeling overwhelmed or intimidated.
This volume contains the proceedings of a two-day multidisciplinary conference on the ethical implications of brain research organized by Stanford University and the University of California, San Francisco. Leaders in neuroscience, journalism, law, and philosophy, among other fields, engaged in a freewheeling debate on the social and individual effects of the research. Steven Marcus has edited their formal and informal deliberations to present a compelling first-hand account of the proceedings, providing a highly readable front-row seat about the first-ever symposium on neuroethics.
Gordon M. Shepherd, a leading neuroscientist at Yale University, embarks on an eye-opening trip through the human brain's "flavor system," establishing the parameters of a new field: neurogastronomy. Challenging the belief that humans' sense of smell diminished as they made the leap from primate to human, Shepherd contends this sense, the main element of flavor, is far more powerful and important than we think. Shepherd begins with the mechanics of smell, the way it stimulates the nose as it hits the back of the mouth. From the food we eat, the brain represents smells as spatial patterns, and out of these, it constructs flavor. He then considers the effect of the flavor system on many contemporary social, behavioral, and medical issues. He analyzes flavor's engagement with the brain regions controlling emotion, food preferences, and cravings, and he even devotes a section to food's role in drug addiction and, building on Proust's iconic tale of the madeleine, its ability to evoke deep memories. Shepherd discusses the link between his research and trends in nutrition, dieting, and obesity, particularly the challenge to eat healthy. He concludes with human perceptions of smell and flavor and their insight into the neural basis of consciousness. Everyone from casual diners and amateur foodies to wine critics, chefs, scholars, and researchers will be thrilled by Shepherd's scientific-gastronomic adventures.
Modern neuroimaging offers tremendous opportunities for gaining insights into normative development and a wide array of developmental neuropsychiatric disorders. Focusing on ontogeny, this text covers basic processes involved in both healthy and atypical maturation, and also addresses the range of neuroimaging techniques most widely used for studying children. This book will enable you to understand normative structural and functional brain maturation and the mechanisms underlying basic developmental processes; become familiar with current knowledge and hypotheses concerning the neural bases of developmental neuropsychiatric disorders; and learn about neuroimaging techniques, including their unique strengths and limitations. Coverage includes normal developmental processes, atypical processing in developmental neuropsychiatric disorders, ethical issues, neuroimaging techniques and their integration with psychopharmacologic and molecular genetic research approaches, and future directions. This comprehensive volume is an essential resource for neurologists, neuropsychologists, psychiatrists, pediatricians, and radiologists concerned with normal development and developmental neuropsychiatric disorders.
This up-to-date, superbly illustrated book is a practical guide to the effective use of neuroimaging in the patient with sleep disorders. There are detailed reviews of new neuroimaging techniques - including CT, MRI, advanced MR techniques, SPECT and PET - as well as image analysis methods, their roles and pitfalls. Neuroimaging of normal sleep and wake states is covered plus the role of neuroimaging in conjunction with tests of memory and how sleep influences memory consolidation. Each chapter carefully presents and analyzes the key findings in patients with sleep disorders indicating the clinical and imaging features of the various sleep disorders from clinical presentation to neuroimaging, aiding in establishing an accurate diagnosis. Written by neuroimaging experts from around the world, Neuroimaging of Sleep and Sleep Disorders is an invaluable resource for both researchers and clinicians including sleep specialists, neurologists, radiologists, psychiatrists, psychologists.
Now completely updated with the latest information on both adult and pediatric patients, this comprehensive book provides a link between the pathophysiology of neurologic deficits and possible rehabilitation interventions for improving movement outcomes. It introduces the structure and function of the nervous system and describes normal motor development, motor control and motor learning, pathophysiology of the nervous system and common treatment techniques used in physical therapy practice. This edition also features updated terminology from the APTA's Guide to Physical Therapist Practice, as well as new chapters on proprioceptive neuromuscular facilitation (PNF) and other neurological conditions seen in the adult. Helpful learning aids and abundant illustrations highlight key concepts and help readers quickly master the material. Helpful learning aids - such as objectives, tables, illustrated intervention boxes, and review questions - reinforce important facts and concepts. Review questions at the end of each chapter allow readers to test their understanding of the material. 700 illustrations clearly depict procedures discussed in the text and clarify descriptions of anatomy, physiology, evaluation, pathology, and treatment. Background information is provided for interventions that can be used in the rehabilitation of adults and children, promoting a complete understanding of techniques. Careful documentation uses current outcomes-based research. Case histories include subjective and objective observation, assessment, planning, and critical decision-making components. Current language of the APTA's Guide to Physical Therapist Practice, 2nd Edition is used throughout, aligning all information with best practices put forth by the APTA. A new chapter on proprioceptive neuromuscular facilitation (PNF) describes how these techniques can be used to improve performance of functional tasks by increasing strength, flexibility, and range of motion.
Neurological, Psychiatric, and Developmental Disorders: Meeting the Challenge in the Developing Worldby Institute of Medicine
Brain disorders—neurological, psychiatric, and developmental—now affect at least 250 million people in the developing world, and this number is expected to rise as life expectancy increases. Yet public and private health systems in developing countries have paid relatively little attention to brain disorders. The negative attitudes, prejudice, and stigma that often surround many of these disorders have contributed to this neglect. Lacking proper diagnosis and treatment, millions of individual lives are lost to disability and death. Such conditions exact both personal and economic costs on families, communities, and nations. The report describes the causes and risk factors associated with brain disorders. It focuses on six representative brain disorders that are prevalent in developing countries: developmental disabilities, epilepsy, schizophrenia, bipolar disorder, depression, and stroke. The report makes detailed recommendations of ways to reduce the toll exacted by these six disorders. In broader strokes, the report also proposes six major strategies toward reducing the overall burden of brain disorders in the developing world.
There are over 600 neuromuscular disorders and the variability of these syndromes can leave clinicians feeling as if they are lost in a maze as they seek to diagnose and manage patients. This book addresses this problem by using the case-history and symptom manifestation as a starting point for the diagnostic process in adult patients, mimicking the situation in the consultation room. For each case, diagnostic tools, disease pathogenesis, prognosis and treatment options are discussed, along with rare manifestations and differential diagnoses. Symptoms, signs and syndromes are cross-linked to help the reader navigate the variety of disorders. Accompanying tables give a broader picture of the manifestations of a particular disease within the landscape of neuromuscular disorders. This highly-illustrated book, with accompanying videos, will aid neurologists at all levels, internists, geneticists, rehabilitation physicians and researchers in the field, as they seek to familiarize themselves with this complex range of disorders.
Presents a new view of psychiatry, blending traditional biologic, neuro- and descriptive psychiatry into a broad neuropsychiatric approach to diagnosis and treatment. Incorporating step-by-step assessment and management strategies, Taylor provides a practical guide for clinical care.
Essential to the management of patients suffering from neurological disorders is an understanding of the cognitive aspects of these conditions. This book begins with an outline of the various cognitive domains and how they can be tested, before covering in depth the cognitive deficits seen not only in prototypical neurodegenerative cognitive disorders (Alzheimer's disease, frontotemporal dementias, Huntington's disease, prionoses), but also in other common neurological disorders which may be complicated by cognitive impairment (stroke, multiple sclerosis, Parkinson's disease, brain tumours). This book is an essential reference text for all neurologists, not just those with an interest in cognitive disorders; and for general physicians and specialists who deal with any endocrine, metabolic, vascular, or infective disorders which may compromise cognitive function. Practitioners of professions allied to medicine which involve contact with cognitively impaired patients will also find this text useful.
Neuroscience: Exploring the Brain surveys the organization and function of the human nervous system, presenting material at the cutting edge of neuroscience, in a way that is accessible to both science and nonscience students alike. The book is divided into four parts: Part I, Foundations; Part II, Sensory and Motor Systems; Part III, The Brain and Behavior; and Part IV, The Changing Brain.
It isn't easy to stop smoking. Yet according to the American Lung Association, well over 45 million Americans have already quit. How did they do it? They found the method that worked for them and they stuck to it. Often, it wasn't the first method they tried. In fact, most smokers attempt to quit several times before they are successful--before they find the technique that works for them. This book can help you find the method that's right for you so that you never smoke again. Never Smoke Again begins by taking a long, hard look at cigarettes, at why you smoke them, and at how they keep you coming back for more--even when you want desperately to toss them away. It then presents ten chapters, each of which focuses on one of the top ten techniques for quitting smoking: * COLD TURKEY * TAPERING OFF * NICOTINE PATCH * NICOTINE GUM * NICOTINE LOZENGES * NICOTINE NASAL SPRAY * NICOTINE INHALER * ZYBAN * CHANTIX * HYPNOSIS For each stop-smoking method, you'll discover what the method is, how it works, how you can best use it, what its risks and drawbacks are, and how effective it is compared with other available techniques. Special Pros and Cons sections highlight the important features of each method, making it easier to pick the tool or tools that are most suited to your needs. A Resources list guides you to organizations that can provide further information and support, rounding out your arsenal of anti-smoking weapons. You have within you the strength and resolve needed to kick the smoking habit forever. Never Smoke Again will show you how to access that power, team it up with a proven quitting technique, and begin a new, healthy, cigarette-free life.
This dictionary and manual helps in two ways: first, it translates medical terms and phrases into language that can be easily understood, and second, it supplies medical information in simple form so that it can be interpreted readily by those who are unfamiliar with medical matters.
This book details a program to significantly slow the biological aging process by using diet, exercise, hormonal supplements, etc.
Read the book that revolutionized the Atkins diet for a whole new generation! This New York Times bestseller explains WHY Atkins is the safest and most effective way to eat, HOW you can use the diet to easily lose pounds and maintain a healthy weight, and WHAT to eat to feel satisfied, every day.The New Atkins Made Easy made a lot of people reexamine what they THOUGHT they knew about low-carb diets. The New Atkins is... Powerful: Learn how to eat the wholesome foods that will turn your body into an amazing fat-burning machine. Easy: The updated and simplified program was created with you and your goals in mind. Healthy: Atkins is about eating delicious and healthy food--a variety of protein, leafy greens and other vegetables, nuts, fruits, and whole grains. Flexible: Perfect for busy lifestyles--you can stick with Atkins at work, at home, on vacation, when you're eating out--wherever you are. Backed by Science: More than eighty studies support the low-carb science behind Atkins. But Atkins is more than just a diet. This healthy lifestyle focuses on maintenance from Day 1, ensuring that you'll not only take the weight off--you'll keep it off for good. Featuring inspiring success stories, all-new recipes, and twenty-four weeks' worth of meal plans, The New Atkins for a New You offers the proven low-carb plan that has worked for millions, now totally updated and even easier than ever.
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