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Wrong Place, Wrong Time: Trauma and Violence in the Lives of Young Black Men
by John A. RichNamed One of the Top 20 Books of 2009 by Cleveland Plain DealerMedical school taught John Rich how to deal with physical trauma in a big city hospital but not with the disturbing fact that young black men were daily shot, stabbed, and beaten. This is Rich's account of his personal search to find sense in the juxtaposition of his life and theirs.Young black men in cities are overwhelmingly the victims—and perpetrators—of violent crime in the United States. Troubled by this tragedy—and by his medical colleagues' apparent numbness in the face of it—Rich, a black man who grew up in relative safety and comfort, reached out to many of these young crime victims to learn why they lived in a seemingly endless cycle of violence and how it affected them. The stories they told him are unsettling—and revealing about the reality of life in American cities.Mixing his own perspective with their seldom-heard voices, Rich relates the stories of young black men whose lives were violently disrupted—and of their struggles to heal and remain safe in an environment that both denied their trauma and blamed them for their injuries. He tells us of people such as Roy, a former drug dealer who fought to turn his life around and found himself torn between the ease of returning to the familiarity of life on the violent streets of Boston and the tenuous promise of accepting a new, less dangerous one.Rich's poignant portrait humanizes young black men and illustrates the complexity of a situation that defies easy answers and solutions.
WSES Handbook of Mass Casualties Incidents Management (Hot Topics in Acute Care Surgery and Trauma)
by Yoram Kluger Federico Coccolini Fausto Catena Luca AnsaloniThis manual, written by world opinion leaders in the field, is designed to provide readily accessible, step-by-step guidance on all aspects of the management of mass casualty incidents. Readers will find a wealth of helpful practical suggestions as well as information on the latest relevant scientific advances and their implications. Globally, mass casualty incidents are becoming more frequent even in unexpected places. There is a need for a dependable manual suitable for use by all who must be prepared to face mass casualty incidents, including practicing physicians, surgeons, anesthesiologists, nurses, and administrators. This book meets that need. It is the first practical manual to be devoted to the topic, and its portable format will allow it to be kept in the pocket at all times, ready for immediate consultation. The innovative nature of much of the content and the inclusion of up-to-date literature reviews ensure that the manual will remain relevant for years to come.
The Wuhan Cover-Up: And the Terrifying Bioweapons Arms Race (Children’s Health Defense)
by Robert F. Kennedy Jr.&“RFK Jr. exposes the decades of lies.&”—Luc Montagnier, Nobel laureate From the New York Times, Wall Street Journal, USA Today, and Publishers Weekly bestselling author of The Real Anthony Fauci comes an explosive exposé of the cover-up behind the true origins of COVID-19. &“Gain-of-function&” experiments are often conducted to deliberately develop highly virulent, easily transmissible pathogens for the stated purpose of developing preemptive vaccines for animal viruses before they jump to humans. More insidious is the &“dual use&” nature of this research, specifically directed toward bioweapons development. The Wuhan Cover-Up pulls back the curtain on how the US government's increase in biosecurity spending after the 2001 terror attacks set in motion a plan to transform the National Institute of Allergy and Infectious Diseases (NIAID), under the direction of Dr. Anthony Fauci, into a de facto Defense Department agency. While Dr. Fauci zealously funded and pursued gain-of-function research, concern grew among some scientists and government officials about the potential for accidental or deliberate release of weaponized viruses from labs that might trigger worldwide pandemics. A moratorium was placed on this research, but true to form, Dr. Fauci found ways to continue unperturbed—outsourcing some of the most controversial experiments offshore to China and providing federal funding to Wuhan Institute of Virology's (WIV's) leading researchers for gain-of-function studies in partnership with the Chinese military and the Chinese Communist Party. Robert F. Kennedy Jr.'s meticulously researched and rigorously sourced analysis leads readers on a staggering journey to learn about: the key enablers and henchmen pushing for gain-of-function research the economic motives behind gain-of-function research successfully engineered &“chimeric viruses&” that can infect and kill humans the coordinated effort to silence speculation of COVID-19&’s laboratory genesis the complicity of scientific journals to hide the origins of COVID-19 the role of the Wuhan Institute of Virology in China&’s biowarfare/biodefense program the relationships between US health, military, and intelligence bureaucracies and scientists and their Chinese counterparts the roles of Bill Gates and Sir Jeremy Farrar in orchestrating a global cover-up The Wuhan Cover-Up unveils a global conspiracy of epic proportion and lethal consequence.
Wuhan Diary: Dispatches from a Quarantined City
by Fang FangFrom one of China’s most acclaimed and decorated writers comes a powerful first-person account of life in Wuhan during the COVID-19 outbreak.On January 25, 2020, after the central government imposed a lockdown in Wuhan, acclaimed Chinese writer Fang Fang began publishing an online diary. In the days and weeks that followed, Fang Fang’s nightly postings gave voice to the fears, frustrations, anger, and hope of millions of her fellow citizens, reflecting on the psychological impact of forced isolation, the role of the internet as both community lifeline and source of misinformation, and most tragically, the lives of neighbors and friends taken by the deadly virus. A fascinating eyewitness account of events as they unfold, Wuhan Diary captures the challenges of daily life and the changing moods and emotions of being quarantined without reliable information. Fang Fang finds solace in small domestic comforts and is inspired by the courage of friends, health professionals and volunteers, as well as the resilience and perseverance of Wuhan’s nine million residents. But, by claiming the writer´s duty to record she also speaks out against social injustice, abuse of power, and other problems which impeded the response to the epidemic and gets herself embroiled in online controversies because of it.As Fang Fang documents the beginning of the global health crisis in real time, we are able to identify patterns and mistakes that many of the countries dealing with the novel coronavirus have later repeated. She reminds us that, in the face of the new virus, the plight of the citizens of Wuhan is also that of citizens everywhere. As Fang Fang writes: “The virus is the common enemy of humankind; that is a lesson for all humanity. The only way we can conquer this virus and free ourselves from its grip is for all members of humankind to work together.” Blending the intimate and the epic, the profound and the quotidian, Wuhan Diary is a remarkable record of an extraordinary time. Translated from the Chinese by Michael Berry
Wundheilung in der Handtherapie und Redressionsprinzipien: Ein Überblick für Handtherapeuten (essentials)
by Ansgar Sanning Ton A.R. SchreudersDieses essential fasst die Grundlagen der Wundheilung und ihre Phaseneinteilung zusammen und bietet Praktikern einen Überblick über die ablaufenden Prozesse, um eine fundierte und an das jeweilige Wundheilungsstadium angepasste Behandlung zu ermöglichen. Insbesondere wird die Rolle der Fibroblasten und ihrer Enzyme als wesentlicher Faktor der Gewebsneubildung, Gewebeanpassung und Kontrakturbildung dargestellt. Es wird gezeigt, dass Fibroblasten auf mechanische und chemische Reize reagieren und sich durch Therapie und Schienenversorgung positiv beeinflussen lassen. Die Autoren nehmen die Wirkung der Fibroblasten zum Ausgangspunkt und zeigen, wie der gezielte Einsatz von Orthesen die Range of Motion (ROM) erweitern kann. Zu diesem Zweck werden unterschiedlich intensiv wirkende Schienenformen vorgestellt.
Wyllie's Treatment of Epilepsy: Principles and Practice
by Elaine WyllieComprehensive, yet accessible, Wyllie’s Treatment of Epilepsy: Principles and Practice has provided a detailed and cohesive overview of seizure disorders and treatment options through six well-regarded editions. The 7th Edition remains the definitive reference in the field with extensive updates from Dr. Elaine Wyllie and her team of world-renowned editors and authors. Ideal for both clinical reference and exam preparation, this single-volume work on contemporary epileptology is an indispensable resource for neurologists, epilepsy specialists and epilepsy neurosurgeons, neurology and neurosurgery residents and fellows, and neuropsychologists.
X-Events: The Collapse of Everything
by John L. CastiA necessary and thought-provoking read for the age of coronavirus, exploring eleven scenarios that may trigger the collapse of the modern world — from pandemics to nuclear apocalypse to robot uprisings — and what we can do to prevent and survive them. In the twenty first century, our world has become impossibly complicated, relying on ever more advanced technology that is developing at an exponential rate. Yet it is a fact of mathematical life that higher and higher levels of complexity lead to systems that are increasingly fragile and susceptible to sudden, spectacular collapse.In this highly provocative and grippingly readable book, John Casti brilliantly argues that today’s advanced, overly complex societies have grown highly vulnerable to extreme events that will ultimately topple civilization like a house of cards. Like Nassim Taleb’s The Black Swan meets Jared Diamond’s Collapse, Casti’s book provides a much-needed wake-up call, sounding a fascinating and frightening warning about civilized society’s inability to recover from a global catastrophe.An eye-opening and necessary read, X-Events is a shocking look at a world teetering on the brink of collapse, and a population under constant threat from pandemic viruses, worldwide communication breakdowns, nuclear winter, or any number of unforeseeable “X-Events.” Fascinating and chilling, X-Events provides a provocative tour of the catastrophic outlier scenarios that could quickly send us crashing back to the preindustrial age – and shows that they may not be as far-fetched as they seem.
X-Ray Computed Tomography in Biomedical Engineering
by Robert CierniakComputed Tomography gives a detailed overview of various aspects of computed tomography. It discusses X-ray CT tomography from a historical point of view, the design and physical operating principles of computed tomography apparatus, the algorithms of image reconstruction and the quality assessment criteria of tomography scanners. Algorithms of image reconstruction from projections, a crucial problem in medical imaging, are considered in depth. The author gives descriptions of the reconstruction methods related to tomography scanners with a parallel X-ray beam, trough solutions with fan-shaped beam and successive modifications of spiral scanners. Computed Tomography contains a dedicated chapter for those readers who are interested in computer simulations based on studies of reconstruction algorithms. The information included in this chapter will enable readers to create a simulation environment in which virtual tomography projections can be obtained in all basic projection systems. This monograph is a valuable study on computed tomography that will be of interest to advanced students and researchers in the fields of biomedical engineering, medical electronics, computer science and medicine.
X-ray Contrast Agent Technology: A Revolutionary History
by Christoph de HaenThis book documents the fascinating history of radiological techniques that use contrast agents. The text includes many of the fundamental documentary sources that bring to life the social and scientific background of the discoveries, the personalities of the discoverers, and implementation of new technologies. Such agents when used with X-rays allow clinicians to distinguish anatomical structures with nearly identical densities. Focus is on urological and angiographic uses of contrast agents. Key selling features: Documents and thoroughly references the history of contrast agent development Reviews the priority and importance of patents Discusses the role that important individual scientists and leading research institutions have played in technology development and implementation
X-Ray Diffraction Imaging: Technology and Applications (Devices, Circuits, and Systems)
by Joel GreenbergThis book explores novel methods for implementing X-ray diffraction technology as an imaging modality, which have been made possible through recent breakthroughs in detector technology, computational power, and data processing algorithms. The ability to perform fast, spatially-resolved X-ray diffraction throughout the volume of a sample opens up entirely new possibilities in areas such as material analysis, cancer diagnosis, and explosive detection, thus offering the potential to revolutionize the fields of medical, security, and industrial imaging and detection. Featuring chapters written by an international selection of authors from both academia and industry, the book provides a comprehensive discussion of the underlying physics, architectures, and applications of X-ray diffraction imaging that is accessible and relevant to neophytes and experts alike. Teaches novel methods for X-ray diffraction imaging Comprehensive and self-contained discussion of the relevant physics, imaging techniques, system components, and data processing algorithms Features state-of-the-art work of international authors from both academia and industry. Includes practical applications in the medical, industrial, and security sectors
X-ray Imaging of the Soil Porous Architecture
by Sacha Jon Mooney Iain M. Young Richard J. Heck Stephan PethThe advent of X-ray Computed Tomography (CT) as a tool for the soil sciences almost 40 years ago has revolutionised the field. Soil is the fragile, thin layer of material that exists above earth’s geological substrates upon which so much of life on earth depends. However a major limitation to our understanding of how soils behave and function is due to its complex, opaque structure that hinders our ability to assess its porous architecture without disturbance. X-ray imagery has facilitated the ability to truly observe soil as it exists in three dimensions and across contrasting spatial and temporal scales in the field in an undisturbed fashion. This book gives a comprehensive overview of the “state of the art” in a variety of application areas where this type of imaging is used, including soil water physics and hydrology, agronomic management of soils, and soil-plant-microbe interactions. It provides the necessary details for entry level readers in the crucial areas of sample preparation, scanner optimisation and image processing and analysis. Drawing on experts across the globe, from both academia and industry, the book covers the necessary “dos and don’ts”, but also offers insights into the future of both technology and science. The wider application of the book is provided by dedicated chapters on how the data from such imagery can be incorporated into models and how the technology can be interfaced with other relevant technical applications. The book ends with a future outlook from the four editors, each of whom has over 20 years of experience in the application of X-ray CT to soil science.
X-Ray Imaging Systems for Biomedical Engineering Technology: An Essential Guide
by Euclid SeeramThis book addresses X-Ray Imaging Systems intended for biomedical engineering technology students and practitioners, and deals with the major technical components of x-ray imaging modalities. These modalities include film-based imaging, digital radiography, and computed tomography. Furthermore, principles and concepts essential to the understanding of how these modalities function will be described. These include fundamental radiation physics, imaging informatics, quality control, and radiation protection considerations. X-Ray Imaging Systems for Biomedical Engineering Technology: An Essential Guide is intended for biomedical engineering technologists, who provide technical advice and services relating to digital radiography and CT departments not only in hospitals but in private facilities as well. Students in radiological technology programs may also find this to be a useful resource.
X-Ray Phase-Contrast Tomography: Underlying Physics and Developments for Breast Imaging (Springer Theses)
by Luca BrombalX-ray imaging is a corner stone of breast cancer diagnosis. By exploiting the phase shift of X-rays rather than their attenuation, phase-contrast tomography has the potential to dramatically increase the visibility of small and low contrast features, thus leading to better diagnosis. This thesis presents research on the first synchrotron-based project developing a clinical phase-contrast breast computed tomography (CT) setup at Elettra, the Italian Syncrotron Radiation Facility. This book includes a comprehensive theoretical background on propagation-based phase-contrast imaging, exploring and extending the most recent image formation models. Along with theory, many practical implementation and optimization issues, ranging from detector-specific processing to setup geometry, are tackled on the basis of a large number of experimental evidences. Most of the modelling results and data analysis have general validity, being a valuable framework for optimization of phase-contrast setups. Results obtained at synchrotron are also compared with "real world" laboratory sources: both a first-of-its-kind comparison with one of the few hospital breast CT systems and a state-of-the-art implementation of monochromatic phase-contrast micro-tomography with a conventional rotating anode source are presented. On a more general level, this work sheds a light on the importance of synchrotron-based clinical programs, which are key to trigger the long-anticipated transition of phase-contrast imaging from synchrotrons to hospitals.
X-Ray Spectroscopy with Synchrotron Radiation: Fundamentals and Applications (Biological and Medical Physics, Biomedical Engineering)
by Stephen P. CramerSynchrotron radiation has been a revolutionary and invaluable research tool for a wide range of scientists, including chemists, biologists, physicists, materials scientists, geophysicists. It has also found multidisciplinary applications with problems ranging from archeology through cultural heritage to paleontology. The subject of this book is x-ray spectroscopy using synchrotron radiation, and the target audience is both current and potential users of synchrotron facilities. The first half of the book introduces readers to the fundamentals of storage ring operations, the qualities of the synchrotron radiation produced, the x-ray optics required to transport this radiation, and the detectors used for measurements. The second half of the book describes the important spectroscopic techniques that use synchrotron x-rays, including chapters on x-ray absorption, x-ray fluorescence, resonant and non-resonant inelastic x-ray scattering, nuclear spectroscopies, and x-ray photoemission. A final chapter surveys the exciting developments of free electron laser sources, which promise a second revolution in x-ray science. Thanks to the detailed descriptions in the book, prospective users will be able to quickly begin working with these techniques. Experienced users will find useful summaries, key equations, and exhaustive references to key papers in the field, as well as outlines of the historical developments in the field. Along with plentiful illustrations, this work includes access to supplemental Mathematica notebooks, which can be used for some of the more complex calculations and as a teaching aid. This book should appeal to graduate students, postdoctoral researchers, and senior scientists alike.
Xcode 6 Essentials
by Jayant VarmaThis book is aimed at developers who want to make applications for Apple devices with Xcode. iOS developers who have experience using other frameworks and languages can now migrate to Xcode and build creative, native apps.
Xenobiotic Metabolic Enzymes: Bioactivation And Antioxidant Defense
by Chang-Hwei ChenThis book provides a comprehensive, organized, and concise overview of xenobiotic metabolic enzymes and their health implications. The subjects addressed are broad in scope with an emphasis on recent advances in research on biochemical and biomedical aspects of these enzymes. The xenobiotics discussed include not just drugs, but also food, smoke, and other environmental chemicals. The subjects covered in this work include: metabolic enzymes and their catalyzed reactions, reactive intermediates generated from metabolic activation, oxidative stress mediated by electrophilic reactive intermediates, bioactivation - mediated cellular and functional damages, activation of Nrf2 – ARE pathway, genetic variations affecting metabolic enzyme expression, enzyme polymorphisms affecting xenobiotic - mediated toxicity, induction of metabolic enzymes for health benefits, and a diversity of metabolic enzyme modulators.
Xenobiotic Metabolism and Disposition: The Design of Studies on Novel Compounds
by Harry P.A. IllingThis publication explains the principles of the techniques used in disposition and metabolism studies in animals, in man, and in vitro. It includes methods for studying routes and rates of absorption, distribution, metabolism, and excretion of novel compounds and their metabolites. Relevant surgical, whole-body autoradiographic and pharmacokinetic procedures are discussed, together with techniques for separating and identifying metabolites and metabolic path-ways. Information on when the procedures are appropriate, and examples of what they represent, are presented in order to illustrate the value of such studies.
Xenopus: Methods and Protocols (Methods in Molecular Biology #1865)
by Kris VleminckxThis volume explores techniques used to study and experiment with Xenopus in order to model or understand human disease. The chapters in this book cover topics such as implementation of CRISPR/Cas9 and TALEN in Xenopus from the design stage up to the genotyping stage; methods to explore generation of knock-in animals; cancer modelling and in vivo screening of congenital heart disease; electroporation; and phenotyping at the organismal level, cellular level, and proteome level. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and comprehensive, Xenopus: Methods and Protocols is a valuable resource for researchers who are interested in expanding their knowledge of this wide and developing field. This book will aid in keeping Xenopus at the forefront for biochemical, cell biological, and developmental studies and forward it as a preclinical disease model.
Xenopus Protocols
by Stefan Hoppler Peter D VizeDuring the 20th century Xenopus has flourished as an accessible experimental model system for studying vertebrate biology. The second edition of Xenopus Protocols:Post-Genomic Approaches expands upon the previous edition with novel approaches inspired by Xenopus tropicalis and the sequencing of its genome. Xenopus tropicalis genomics and tractable genetics combined with the unique experimental advantages of Xenopus laevis and their distinctive phylogenetic position make them unique model systems for vertebrate embryonic development in the 21st century. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Xenopus Protocols: Post-Genomic Approaches, Second Edition provides a toolkit that will enable every laboratory to maximize the power of this extraordinary experimental system in the post-genomic age.
Xenotransplantation: Science, Ethics, and Public Policy
by Committee on Xenograft Transplantation: Ethical Issues Public PolicyXenotransplantation involves the transplantation of cells, tissues, and whole organs from one species to another. Interest in animal-to-human xenotransplants has been spurred by the continuing shortage of donated human organs and by advances in knowledge concerning the biology of organ and tissue rejection. The scientific advances and promise, however, raise complex questions that must be addressed.This book considers the scientific and medical feasibility of xenotransplantation and explores the ethical and public policy issues surrounding the possibility of renewed clinical trials. The volume focuses on the science base of xenotransplantation, public health risks of infectious disease transmission, and ethical and public policy issues, including the views of patients and their families.
Xenotransplantation: Ethical, Regulatory, and Social Aspects
by Daniel J. Hurst Luz Padilla Wayne D. ParisThis is the first volume to comprehensively discuss the ethical, regulatory, and social aspects of xenotransplantation research.Organized into four parts, Xenotransplantation begins by examining ethical issues around informed consent of the potential xenograft recipient, the major ethical issues encountered when doing this research on pigs, and allocation issues. Part two examines regulatory aspects from a global perspective, specifically from three major regions of the world doing xenotransplantation research currently, of which include the United States, Western Europe, and Asia. Following this, part three describes religious aspects of xenotransplantation amongst the major world religions, including Christianity, Islam, Judaism, and Hinduism. The book closes with an analysis of quantitative and qualitative studies conducted by the editors that assess the public’s perception of xenotransplantation. Featuring original data collected by the editors, this book is an instrumental resource for all clinicians involved in the research and practice of xenotransplantation.
Xenotransplantation and Risk: Regulating a Developing Biotechnology
by Sara FovargueSome developing biotechnologies challenge accepted legal and ethical norms because of the risks they pose. Xenotransplantation (cross-species transplantation) may prolong life but may also harm the xeno-recipient and the public due to its potential to transmit infectious diseases. These trans-boundary diseases emphasise the global nature of advances in health care and highlight the difficulties of identifying, monitoring and regulating such risks and thereby protecting individual and public health. Xenotransplantation raises questions about how uncertainty and risk are understood and accepted, and exposes tensions between private benefit and public health. Where public health is at risk, a precautionary approach informed by the harm principle supports prioritising the latter, but the issues raised by genetically engineered solid organ xenotransplants have not, as yet, been sufficiently discussed. This must occur prior to their clinical introduction because of the necessary changes to accepted norms which are needed to appropriately safeguard individual and public health.
Xie's Chinese Veterinary Herbology
by Huisheng Xie Vanessa PreastXie's Chinese Veterinary Herbology serves as a practical guide to the theory and application of Chinese Herbal Medicine into veterinary practices. Divided into three parts, the book covers herbal materia medica used in treating various disorders and diseases, herbal formulas, and the clinical application of treatments. The book also outlines each herb's history, the formulation of herbal recipes, energetic actions, indications and contraindications of each formula, dosages, and clinical and pharmacological studies performed with herbal treatments. This text serves as an invaluable reference to veterinarians looking to expand treatment options.
Xie's Veterinary Acupuncture
by Huisheng Xie Vanessa PreastTraditional Chinese Veterinary Medicine has been used to treat animals in China for thousands of years. Until now, the majority of the literature on Traditional Chinese Veterinary Medicine has been written in Chinese. Xie's Veterinary Acupuncture serves as a comprehensive and accessible reference on the basic principles, techniques and clinical application of veterinary acupuncture. Written by a world renowned authority on veterinary acupuncture and a panel of experts, the book incorporates a traditional Chinese approach to veterinary acupuncture, including ancient and newly developed acupuncture techniques for both small and large animals. With the growing interest in veterinary acupuncture worldwide, this ground-breaking and authoritative text is a timely resource for practitioners and students alike.
XIIIth International Symposium on Spermatology
by Lars Björndahl John Flanagan Rebecka Holmberg Ulrik KvistThese proceedings of the 2018 XIII International Symposium on Spermatology focus on comparative biology, and encourages discussion and the exchange of ideas. The aim of this Symposium was to provide a unique opportunity and bring together scientists from a wide spectrum of research fields – human, domestic animals and other mammals, vertebrates, insects, and plants. The underlying focus is on the function of the spermatozoon – a common feature for sexual reproduction, but extremely varied. By exploring the variability, a better understanding of male reproductive functions can develop. These proceedings address the mechanisms of physiology and pathophysiology, rather than diagnosis and treatment. The symposium featured keynote lectures by invited speakers, followed by presentations on specific aspects of the general topic of the session. Experimental studies are given priority over clinical studies of patient populations. The proceedings comprise both keynote speakers' texts and selected free communications. Posters were considered for publication in the proceedings, and the volume includes exhibited materials on the work of prominent spermatologists, highlighting their important past achievements in the field.