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Bone and Joint Infections: From Microbiology to Diagnostics and Treatment
by Werner ZimmerliBONE AND JOINT INFECTIONS Explore this comprehensive presentation of bone and joint infections, including non-implant and implant-associated orthopedic infectionsIn the newly revised Second Edition of Bone and Joint Infections: From Microbiology to Diagnostics and Treatment, accomplished researcher and author Werner Zimmerli delivers a comprehensive overview of the most recent developments in the subject of bone and joint infection. Covering much of the new information appearing over the last five years, the book includes four new chapters presenting the diagnostic approach in bone and joint infections, discussing the identification of pathogens by non-culture techniques, management of multi-resistant bacteria in bone and joint infections by bacteriophages, and unusual microorganisms in periprosthetic joint infections.Many of the chapters are also updated to include new information on topics like eubacterial PCR, multiplex PCR, and the shotgun metagenomics approach. These subjects are of increased applicability and interest to increase the fraction of cases with identified pathogens. The book also helps clinicians to understand MRI-based images and rapidly interpret and plan for comprehensive therapy.Readers will also benefit from the inclusion of:A thorough introduction to the pharmacokinetics and pharmacodynamics of antibiotics in bone and preclinical models of infection in bone and joint surgeryAn exploration of native joint arthritis in children and adults, as well as an overview of septic arthritis of axial jointsA practical discussion of the general aspects of periprosthetic joint infection, as well as specific aspects of periprosthetic joint infection after total hip and knee, shoulder, elbow, and ankle arthroplastyA concise treatment of osteomyelitis in children and adultsPerfect for infectious disease specialists, microbiologists, orthopedic and trauma surgeons, and internists, Bone and Joint Infections: From Microbiology to Diagnostics and Treatment will also earn a place in the libraries of professionals working in the implant industry and pharmaceuticals, as well as clinical pharmacologists and rheumatologists.
Autism: Current Theories and Evidence (Current Clinical Neurology)
by Andrew W. ZimmermanCreative thinking and collaborative scientific research have advanced our understanding of autism, and we are now beginning to synthesize the data into evidence and theories. Autism: Current Theories and Evidence presents current theories about autism and the evidence that supports them. The goal is to show how the scientific method is revealing the biological bases of this spectrum of disorders, thereby leading the way to their treatment and prevention using evidence-based medicine. This book has 20 chapters divided into 6 sections: Molecular and Clinical Genetics; Neurotransmitters and Cell Signaling; Endocrinology, Growth and Metabolism; Immunology, Maternal-Fetal Effects and Neuroinflammation; Neuroanatomy, Imaging and Neural networks; and Environmental Mechanisms and Models. The subjects cover a wide range of current scientific work in the field of autism, with strong and growing evidence to support them, and demonstrate both the breadth and depth of current autism research. The reader is encouraged to consider how theories and the scientific method, in the hands of these and other dedicated researchers, are leading to greater knowledge and continued progress in autism research.
Researching Health Together: Engaging Patients and Stakeholders, From Topic Identification to Policy Change
by Emily B. ZimmermanThe challenges of addressing health disparities, the ethical imperative to include stakeholders in research, and the slow translation of research evidence into practice are all driving a movement towards more community-based and participatory approaches to research. Researching Health Together brings together authors who have produced innovative methods or implemented projects focused on different stages of the research process, from question development to evaluation and translation. Editor Emily B. Zimmerman gathers exemplary new methods and projects into one place for the benefit of students designing research projects and proposals, those learning stakeholder-engaged methods, and those involved in implementing and funding stakeholder-engaged projects. Each chapter addresses: how engagement was conceptualized, organized, and implemented; how engagement was evaluated; impacts on processes and outcomes of the project; and facilitators, barriers, and lessons learned. The book serves as a core textbook for courses in community-based health research at the graduate level.
Researching Health Together: Engaging Patients and Stakeholders, From Topic Identification to Policy Change
by Emily B. ZimmermanThe challenges of addressing health disparities, the ethical imperative to include stakeholders in research, and the slow translation of research evidence into practice are all driving a movement towards more community-based and participatory approaches to research. Researching Health Together brings together authors who have produced innovative methods or implemented projects focused on different stages of the research process, from question development to evaluation and translation. Editor Emily B. Zimmerman gathers exemplary new methods and projects into one place for the benefit of students designing research projects and proposals, those learning stakeholder-engaged methods, and those involved in implementing and funding stakeholder-engaged projects. Each chapter addresses: how engagement was conceptualized, organized, and implemented; how engagement was evaluated; impacts on processes and outcomes of the project; and facilitators, barriers, and lessons learned. The book serves as a core textbook for courses in community-based health research at the graduate level.
Diseases of Swine
by Jeffrey J. Zimmerman Locke A. Karriker Alejandro Ramirez Kent J. Schwartz Gregory W. Stevenson Jianqiang ZhangProvides a fully revised Eleventh Edition of the definitive reference to swine health and disease Diseases of Swine has been the definitive reference on swine health and disease for over 60 years. This new edition has been completely revised to include the latest information, developments, and research in the field. Now with full color images throughout, this comprehensive and authoritative resource has been redesigned for improved consistency and readability, with a reorganized format for more intuitive access to information. Diseases of Swine covers a wide range of essential topics on swine production, health, and management, with contributions from more than 100 of the foremost international experts in the field. This revised edition makes the information easy to find and includes expanded information on welfare and behavior. A key reference for anyone involved in the swine industry, Diseases of Swine, Eleventh Edition: Presents a thorough revision to the gold-standard reference on pig health and disease Features full color images throughout the book Includes information on the most current advances in the field Provides comprehensive information on swine welfare and behavior Offers a reorganized format to make the information more accessible Written for veterinarians, academicians, students, and individuals and agencies responsible for swine health and public health, Diseases of Swine, Eleventh Edition is an essential guide to swine health.
The A. D. D. Nutrition Solution: A Drug-Free Thirty-Day Plan
by Marcia ZimmermanThe first scientifically proven, effective, all-natural nutritional alternative to the much-prescribed drug Ritalin. Attention deficit disorder is a nutritional deficiency, not a psychological condition. This is the revolutionary discovery Marcia Zimmerman made during her ten years of research as a nutritional biochemist. That conclusion led her to develop a diet that addresses the specific needs of the 17 million adults and children suffering from ADD. Her easy-to-follow thirty-day plan has been proven just as effective as Ritalin in relieving the symptoms of ADD. Learn: - How women should boost their nutrition before conception to prevent ADD in their children. - Why boys are much likelier to be tagged as ADD than girls - How to get a reliable ADD diagnosis Reasons why parents prefer a diet plan to prescription drugs for ADD children - The effects of brain allergies on attention span - Foods to avoid that may exacerbate ADD - Fats and oils we all need to stay focused - Calming effects of carbohydrates - Concentration-enhancing protein - Why to stay away from simple sugars - The dangers of artificial food ingredients, and much more This important book will help us curb the epidemic growth of ADD in this country and change the way we treat those who have it now by addressing its source instead of merely treating its symptoms.
Interview Guide for Evaluating DSM-5 Psychiatric Disorders and the Mental Status Examination
by Mark Zimmerman<p>This book provides questions for evaluating psychiatric disorders. DSM-5 lists the disorders and their criteria, but it does not guide the beginner in inquiry for them. Students and clinicians in training are relatively unfamiliar with psychiatric diagnoses, and they cannot possibly remember all of the disorders and their corresponding diagnostic criteria within a short period of study. Moreover, it is often not obvious what questions to ask to determine the symptom's presence. How do you inquire for thought withdrawal, delusions of reference, panic attacks, obsessions, identity disturbance, mood instability, etc? Even more basic, how do you begin the interview? <p>The Interview Guide consists of questions for the most common DSM-5 diagnoses including the personality disorders. This book is not a standardized interview, to be started on page x and followed until page xx. Rather it is a quick reference to be used in the context of a clinical interview. If a patient complains of depression, the interviewer can turn to the section on major depression and assess the relevant symptoms. If there is a suggestion of excessive drug or alcohol use, the interviewer can refer to the long list of questions for diagnosing a drug or alcohol use disorder.</p>
Interview Guide For Evaluating DSM-5-TR Psychiatric Disorders and the Mental Status Examination
by Mark ZimmermanThis book provides questions for evaluating psychiatric disorders. DSM-5-TR lists the disorders and their criteria, but it does not guide the beginner in inquiry for them. Students and clinicians in training are relatively unfamiliar with psychiatric diagnoses, and they cannot possibly remember all of the disorders and their corresponding diagnostic criteria within a short period of study. Moreover, it is often not obvious what questions to ask to determine the symptom's presence. How do you inquire for thought withdrawal, delusions of reference, panic attacks, obsessions, identity disturbance, mood instability, etc., Even more basic, how do you begin the interview? The Interview Guide consists of questions for the most common DSM-5 diagnoses including personality disorders. This book is not a standardized interview, to be started on page x and followed until page xx. Rather it is a quick reference to be used in the context of a clinical interview. If a patient complains of depression, the interviewer can turn to the section on major depression and assess the relevant symptoms. The book is organized by diagnosis and contains 9 sections.
The Doula Guide to Birth
by Rachel Zimmerman Ananda LoweHere is your guide to the fastest-growing trend in childbirth—a tradition as old as motherhood itself. Doulas,or professional labor assistants, have led thousands of expectant women through the birthing process in a way that’s safe and meaningful, and that creates the birth and postbirth experience all mothers long for. What exactly dodoulas do? How to find one that suitsyou. What are the “trade secrets” only doulas know but every woman should be aware of (even if youdon’thave a doula)? InThe Doula Guide to Birth,senior-level doula Ananda Lowe and award-winning health reporter Rachel Zimmerman have written a most comprehensive book that draws on the wisdom of these skilled experts, whose experience with doctors, midwives, nurses, and hospitals makes them invaluable advocates before, during, and after birth. * Labor techniques anyone can use * Pain medication: do you, don’t you—and when? * What dads and loved ones need and can do best * When should youreallygo to the hospital in labor? * How to prepare for unexpected medical procedures, including cesareans and epidural * Postpartum—what it’s really like * A clip-out chart of labor techniques, birth plan worksheets, and much more Combining science, wit, warmth, and support, as well as the inspirational stories of dozens of mothers and their partners, you’ll find the “doula viewpoint” on every major pregnancy and delivery issue, making this one of the most important childbirth books you’ll ever read and recommend.
Assisted Living: Needs, Practices, and Policies in Residential Care for the Elderly
by Sheryl ZimmermanWith the number of elderly persons needing long-term care expected to double to 14 million over the next two decades, assisted living has become the popular choice for housing or care. Assisted living represents a promising model of long-term care that blurs the sharp distinction between nursing homes and community-based care and reduces the gap between receiving long-term care in one's own home and in an "institution." Assisted Living: Needs, Practices, and Policies in Residential Care for the Elderly examines the evolving field of residential care and focuses on national issues of regulation, reimbursement, and staffing. The book is based on a four-state study of assisted living facilities and describes the facilities, the persons residing in them and their needs, and how the services vary by facility. Because one-third to two-thirds of residents in assisted living facilities have cognitive impairment, special attention is devoted to dementia care. The book also focuses on how today's long-term health care environment evolved, and it examines the future direction and implications of assisted living.Assisted Living: Needs, Practices, and Policies in Residential Care for the Elderly brings together a group of nationally recognized experts to help define the types of residential care that should be encouraged and sets guidelines for selecting an appropriate type of facility.
Retirement Migration from the U.S. to Latin American Colonial Cities (International Perspectives on Aging #27)
by Sheryl Zimmerman Philip D. Sloane Johanna SilbersackThis book provides a comprehensive overview of a growing phenomenon in migration: retired Americans moving to Latin America. Through in-depth profiles of two of the most popular destinations – Cuenca, Ecuador and San Miguel de Allende, Mexico, the book provides a unique commentary on the social forces shaping this new diaspora and its impact on the settings to which retirees relocate. Sections of the book address the lives and activities of retirees themselves; their impact on real estate, business development, and gentrification within historic cities; the availability and access to medical and long-term care services; and the role of governmental policies in attracting immigrant retirees and shaping their societal impact. Concluding sections provide guidance for potential retirees and for cities and countries interested in attracting these new immigrants while minimizing adverse impact on local culture and quality of life. Carefully researched and extensively illustrated with photographs, maps, figures, and tables, the book serves as an important new resource for scientists and policy makers, as well as for baby boomers who have retired abroad or are considering doing so.
Pearls and Pitfalls in Cardiovascular Imaging
by Zimmerman, Stefan L. and Fishman, Elliot K. Stefan L. Zimmerman Elliot K. FishmanCardiovascular imagers are faced with the challenge of interpreting cases that include artifacts, unusual findings, or anatomic variants on an almost daily basis. These studies can result in confusion and may lead to misdiagnosis even for the most experienced imager. This book provides an approachable reference for practising cardiovascular imagers to aid with both commonly and uncommonly encountered entities that can result in inappropriate patient management. Through the focused use of case examples, this book reviews 100 conditions that can be seen in clinical practice, including pseudotumors, artifacts, anatomic variants, mimics, and unusual diagnoses. Each highly illustrated case follows a standard format, allowing readers to learn from real-life examples and provides an accessible and rapid source of reference for the improved interpretation of cardiovascular imaging and enhanced patient care. This text will be invaluable to radiologists, cardiologists, and trainees.
Biology and Management of Unusual Plasma Cell Dyscrasias
by Todd M. Zimmerman Shaji K. KumarThis unique book focuses on the non-myeloma plasma cell dyscrasias. A key resource for this group of diseases, the book features the latest in emerging knowledge and therapeutic developments, including novel therapies. Each disease-specific chapter discusses biology, disease course, and appropriate therapeutic interventions, covering plasma cell leukemia, plasmacytoma, POEMS Syndrome and Castleman's Disease, Waldenström macroglobulinemia, immunoglobin deposition disease, and cryoglobulinemic syndromes, among others. The only book dedicated to this intriguing family of diseases, Biology and Management of Unusual Plasma Cell Dyscrasias will be a long-lasting reference for clinicians and scientists alike.
Pediatric Liver Tumors
by Arthur Zimmermann Dietrich Von Schweinitz Giorgio Perilongo Marcio MalogolowkinThe field of liver tumors in children has seen tremendous therapeutic advances over recent years. This has been achieved through a much better understanding of the biology of disease, improved diagnostic procedures, refined methods of pretreatment tumor staging, the implementation of highly efficient chemotherapy and surgery, detailed monitoring of toxicity, and careful follow-up strategies. International controlled trials have played a key role in these advances, and many leading figures in the trials are among the editors and authors of this book. Their principal goal in Hepatic Tumors in Children is to provide the reader with a complete update on this complex and rapidly evolving field. All aspects of an impressive success story are covered, disclosing how the outcome of a previously devastating disease has been so dramatically improved. This book will prove essential reading for all who are involved in the care of children with liver tumors.
Meine Frau hat Krebs: Wie gehen wir als Paar mit der Erkrankung um
by Tanja Zimmermann Jochen ErnstDieser Ratgeber richtet sich an Paare, bei denen die Frau an Krebs erkrankt ist, und er bietet besonders den PartnerInnen Unterstützung zur Bewältigung der aufkommenden Belastungen und Herausforderungen. Eine Krebsdiagnose hat Auswirkungen auf nahezu alle Lebensbereiche: auf die Partnerschaft, den Alltag, auf das berufliche und soziale Umfeld. Die Krankheit kann aber auch die Sicht auf das Leben und den Tod nachhaltig verändern und mit teilweise schmerzlichen Erfahrungen verbunden sein. Einfühlsam und konkret sprechen die erfahrenen Autoren alle wesentlichen Punkte an. Das Buch ist praxisbezogen und die Kapitel werden durch viele Beispielen und Übungen ergänzt. Rat, Informationen und Hilfe für Betroffene und Angehörige!
Partial Truths: How Fractions Distort Our Thinking
by James C. ZimringA fast-food chain once tried to compete with McDonald’s quarter-pounder by introducing a third-pound hamburger—only for it to flop when consumers thought a third pound was less than a quarter pound because three is less than four. Separately, a rash of suicides by teenagers who played Dungeons and Dragons caused a panic in parents and the media. They thought D&D was causing teenage suicides—when in fact teenage D&D players died by suicide at a much lower rate than the national average. Errors of this type can be found from antiquity to the present, from the Peloponnesian War to the COVID-19 pandemic. How and why do we keep falling into these traps?James C. Zimring argues that many of the mistakes that the human mind consistently makes boil down to misperceiving fractions. We see slews of statistics that are essentially fractions, such as percentages, probabilities, frequencies, and rates, and we tend to misinterpret them. Sometimes bad actors manipulate us by cherry-picking data or distorting how information is presented; other times, sloppy communicators inadvertently mislead us. In many cases, we fool ourselves and have only our own minds to blame. Zimring also explores the counterintuitive reason that these flaws might benefit us, demonstrating that individual error can be highly advantageous to problem solving by groups. Blending key scientific research in cognitive psychology with accessible real-life examples, Partial Truths helps readers spot the fallacies lurking in everyday information, from politics to the criminal justice system, from religion to science, from business strategies to New Age culture.
Eat This Not That! For Kids!
by David Zinczenko Matt GouldingIt's no secret that children are getting fatter: 17% of this country's youth are overweight or obese, and the number of diabetic children has nearly quadrupled in the past thirty years. Now, to help combat the problem, David Zinczenko, editor-in-chief of Men's Health, and co-author Matt Goulding have created Eat This, Not That! for Kids. This must-have guide for concerned parents offers detailed analysis and nutritional tips on thousands of the most popular food choices for kids. Covering the best and worst options available at the most popular restaurants in the country as well as the healthiest-and most harmful-foods in the supermarket aisles, if kids are eating it, this book is probably analyzing it. Other features include:-Restaurant Report Cards on the best chain restaurants for your kids-Drink This, Not That! for Kids-The 20 Worst Kids' Meals in America-10 Healthy" Foods that Aren't-The 8 Foods You Should Feed Your Kid Every Day"
AARP Special Edition: for a Longer, Leaner, Healthier Life!: The fast, effective weight-loss plan to save you 10, 20, 30 pounds--or more!
by David Zinczenko Eat ThisLose 10, 20, 30 pounds or more, and put yourself back in control of your weight, your health, and your life! Don't diet, don't sacrifice, and don't waste money or time on expensive weight-loss foods. In fact, you can start dropping pounds today while eating all your favorite foods--from pizza and pasta to burgers, and even dessert. From the editors of the bestselling series Eat This, Not That! comes a unique diet program that strips away added sugars and melts fat--from your belly first. The trick: a series of simple swaps that will ensure you're eating the very best options from your favorite restaurants and grocery store brands. Discover how easy it is to indulge your way to a flat belly while protecting your brain and striking a blow against heart disease, diabetes, and more. Eat This, Not That! for a Longer, Leaner, Healthier Life is based on four easy-to-remember nutrition rules: * Use our simple guide to ensure you're always making the smartest, healthiest, leanest choice in any restaurant or grocery store. * Enjoy rich, creamy, healthy fats, so you never feel hungry or deprived, even while your metabolism is revving on high. * Reduce added sugars--without sacrificing flavor--with a series of simple tips that will help you enjoy your favorite desserts, without gaining an ounce! * Power up your day with 10 essential LONGER LIFE Superfoods for maximum health and rapid weight loss. Get ready to drop that extra weight faster than you've ever imagined--and enjoy every bite!
A Clinician's Guide to Sperm DNA and Chromatin Damage
by Armand Zini Ashok AgarwalThis comprehensive, up-to-date text, which brings together the key practical elements of the rapidly evolving field of sperm DNA and chromatin abnormalities, is divided thematically into five main sections. Part I discusses human sperm chromatin structure and nuclear architecture, while part II presents laboratory evaluation of sperm DNA damage, including SCSA, SCD, TUNEL and Comet assays, and cytochemical tests. Biological and clinical factors in the etiology of sperm DNA damage are discussed in part III, including oxidative stress, abortive apoptosis, cancer, and environmental and lifestyle factors. Part IV presents clinical studies on the utility of sperm DNA damage tests, both with natural and ART-assisted pregnancies, and debates the clinical utility of such tests. Finally, part V discusses current treatment options, such as antioxidant therapy, varicocelectomy, advanced sperm processing techniques and the use of testicular sperm. We are now beginning to better understand the unique organization of the sperm chromatin, as well as the nature and etiology of sperm DNA damage. Written and edited by worldwide experts in andrology, A Clinician's Guide to Sperm DNA and Chromatin Damage is an excellent resource for reproductive medicine and REI specialists, urologists, reproductive biologists and any professional working with the infertile male.
Canine Sports Medicine and Rehabilitation
by Chris Zink Janet B. Van DykeCanine Sports Medicine and Rehabilitation, Second Edition offers a thoroughly revised and updated new edition of this gold standard reference for all aspects of sports medicine and rehabilitation, encompassing basic science and integrated veterinary and physical therapy approaches. Presents current, state-of-the-art information on sports medicine and rehabilitation in dogs Offers perspectives from an international list of expert authors Covers all topics related to veterinary care of the canine athlete and all active dogs Includes illustrations and photographs throughout to demonstrate key concepts Provides clinical cases that set the information in context
Dog Health and Nutrition for Dummies
by M. Christine ZinkHelp your dog enjoy a longer and healthier life with the latest in conventional and alternative veterinary medicine.
Fluorescence Lifetime Imaging Ophthalmoscopy
by Martin Zinkernagel Chantal DysliThis book focuses on the emerging non-invasive imaging technique of Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO). FLIO reveals unique information on retinal diseases, ranging from age-related macular degeneration and vascular diseases to hereditary retinal dystrophies. Fluorescence lifetimes enable the evaluation of disease progression before irreversible structural changes occur. The image acquisition is suitable for diagnostic purposes and follow-up examinations to investigate the natural course of disease, and to monitor the effects of possible therapies. This book fills the gap between available literature and gives state-of-the-art guidance on the principles of the FLIO technique, image acquisition, and data analysis. Written by a team of expert leaders within this field, this book will be relevant for scientists and clinicians with an interest in ophthalmoscopy.
Optical Imaging of Cancer
by Kurt R. Zinn Eben RosenthalTo describe principles of optical imaging including chemistry and physics of fluorescence, limitations/advantages of optical imaging compared to metabolic and anatomic imaging. Describe hardware adapted for small animal imaging and for clinical applications: endoscopes and operative microscopes. Outline FDA approved and newer optical imaging probes. Include discussion of chemistry and linkage to other proteins. Review current techniques to image cancer and the development of techniques to specifically image cancer cells. Review use of exploiting differences in tissue autofluorescence to diagnose and treat cancer. Include agents such as 5-aminoleculinic acid. Review mechanisms that require proteolytic processing within the tumor to become active fluorophores. Review use of cancer selective proteins to localize probes to cancer cells: include toxins, antibodies, and minibodies. Introduction of plasmids, viruses or other genetic material may be used to express fluorescent agents in vivo. This chapter will review multiple vectors and delivery mechanisms of optical imaging cassettes.Preclinical investigations into the use of optical contrast agents for the detection of primary tumors in conventional and orthotopic models will be discussed. Preclinical investigations into the use of optical contrast agents for the detection of metastatic tumors in mouse models will be discussed. Use of targeted and non-specific optical contrast agents have been used for the detection of sentinel lymph node detection. These applications and how they differ from other applications will be discussed. Because of the unique difficulty of identifying tumor from normal tissue in brain tissue, a separate chapter would be needed. More clinical data is available for this cancer type than any other. Discussion of potential clinical applications for optical imaging and an assessment of the potential market.
Infectious Lesions of the Central Nervous System
by Vsevolod ZinserlingThis book discusses all aspects infectious CNS pathology, including different bacterial, viral, fungal, mycoplasma and protozoan pathogens, accompanied by illustrations that show macro- and histopathological changes. It also presents microbiological, epidemiological and clinical data, with a particular focus on meningitis and encephalitis of different bacterial and viral aetiologies, influenza, COVID-19 and other viral and bacterial generalized infections. Further, the book explores the importance of mixed infections, including those in the late stages of HIV infection, as well as pathological changes in different age groups including newborns. A special chapter is devoted to the probable role of biological pathogens in noninfectious brain pathology.
Infectious Pathology of the Respiratory Tract
by Vsevolod ZinserlingThis book discusses all aspects of pulmonary pathology, including different bacterial, viral, fungal, mycoplasma and protozoan pathogens, accompanied by illustrations that show macro- and histopathological changes. It also presents microbiological, epidemiological and clinical data, with a particular focus on pneumonias of different bacterial aetiologies, influenza, and other viral infections. Further, the book explores the importance of mixed infections, including those in the late stages of HIV infections and virus-bacterial pneumonias, as well as pathological changes in modern tuberculosis, lung granuloma, and respiratory tract inflammation in different age groups.