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Intelligent Orthopaedics: Artificial Intelligence And Smart Image-guided Technology For Orthopaedics (Advances in Experimental Medicine and Biology #1093)

by Xiahai Zhuang Wei Tian Guoyan Zheng

This book introduces readers to the latest technological advances in the emerging field of intelligent orthopaedics. Artificial intelligence and smart instrumentation techniques are now revolutionizing every area of our lives, including medicine. The applications of these techniques in orthopaedic interventions offer a number of potential benefits, e.g. reduced incision size and scarring, minimized soft tissue damage, and decreased risk of misalignment. Consequently, these techniques have become indispensable for various orthopaedic interventions, which has led to the emerging field of intelligent orthopaedics. Addressing key technologies and applications, this book offers a valuable guide for all researchers and clinicians who need an update on both the principles and practice of intelligent orthopaedics, and for graduate students embarking on a career in this field.​

Electrochemical Sensing: Carcinogens in Beverages

by Asif Iqbal Zia Subhas Chandra Mukhopadhyay

Thisbook describes a robust, low-cost electrochemical sensing system that is able todetect hormones and phthalates - the most ubiquitous endocrine disruptorcompounds - in beverages and is sufficiently flexible to be readily coupledwith any existing chemical or biochemical sensing system. A novel type of silicon substrate-based smart interdigitaltransducer, developed usingMEMS semiconductor fabrication technology, is employed in conjunction with electrochemical impedance spectroscopy to allow real-time detection andanalysis. Furthermore, thepresented interdigital capacitive sensor design offers a sufficient penetrationdepth of the fringing electric field to permit bulk sample testing. The authorsaddress all aspects of the development of the system and fully explain its benefits. The book will be of wide interest to engineers, scientists, and researchersworking in the fields of physical electrochemistry and biochemistry at theundergraduate, postgraduate, and research levels. It will also be highly relevantfor practitioners and researchers involved in the development of electromagneticsensors.

Neurovascular Sonography

by Wendy C. Ziai Christy L. Cornwell

This book provides a comprehensive and concise, review of the fundamental concepts and clinical indications for Transcranial Doppler (TCD) imaging. An overview of the physics of ultrasonography as it pertains to TCD is presented, as well as neuroanatomy and cerebrovascular physiology in healthy and diseased states. Recommended protocols for neuroimaging are reviewed and serves as a guide for existing neurovascular laboratories and medical systems seeking to develop laboratories that are in need of a guide to establish their own protocols. The most common, relevant and challenging clinical conditions where TCD is incorporated to assist with patient management are discussed. In addition, chapters provide a framework for building a neurovascular laboratory, including necessary equipment, steps to obtain national accreditation by accrediting bodies, and reimbursement procedures for tests performed. The book concludes with “clinical pearls” and “tricks of the trade”, which serve as a commentary to guide physicians and neurosonologists on best-practices for TCD acquisition and interpretation.

Modern Dietary Fat Intakes in Disease Promotion

by Sherma Zibadi Fabien De Meester Ronald Ross Watson

The industrial and agricultural revolutions have dramatically changed our lifestyles including where we get foods and what we eat. Modern diets have moved away from a close association with historically beneficial foods and diets towards foods and diets with increased fats and contaminants and with much lower intakes of fruits and vegetables. Modern Dietary Fat Intakes in Disease Promotion focuses on the scientific evidence that define such risks in modern diets with the consequences of increased illness, cancer and disease. There is also an emphasis on methods to reverse negative components of modern diets for health improvement. The volume is divided into six sections. The first section focuses on the behavioral aspects of eating and is followed by sections on fats, obesity and cardiovascular disease and fats and cholesterol. The fourth section contains novel chapters on the potential for contaminants in fats and oils to increase risk of illnesses. The fifth section examines fat induced disease and ill-health. The sixth section looks at dietary and pharmaceutical approaches to modify fat-induced disease and ill-health. Each section contains chapters that address treatment options as well as prevention strategies. Modern Dietary Fat Intakes in Disease Promotion provides practical, data-driven resources based upon the totality of the evidence to help the reader understand both the basics as well as treatments and preventive strategies that are involved in balancing the fats in one's diet as well as within one's body.

Magnesium in Human Health and Disease

by Sherma Zibadi Victor R. Preedy Ronald Ross Watson

Magnesium is an essential mineral which is required for growth and survival of humans. Since magnesium is a mineral and not synthesizable it must be obtained through dietary foods and/or supplements. Magnesium in Human Health and Disease reviews the benefits of magnesium supplementation to reach recommended intakes as well as provides new research that suggests how reaching levels above the recommended intakes can promote health and treat various diseases. Magnesium deficiency can cause low serum potassium and calcium levels, retention of sodium, and low circulating levels of regulatory hormones. These changes in nutrients cause neurological and muscular symptoms such as tremor and muscle spasms. Further magnesium deficiency causes loss of appetite, nausea, vomiting, personality changes and death from heart failure. Causes of magnesium deficiency include alcohol abuse, poorly controlled diabetes, excessive or chronic vomiting and/or diarrhea. Thus the effects of inadequate and deficient intakes or levels of magnesium is critical to health and are reviewed by the expert clinicians in this book. Magnesium in Human Health and Disease provides the most current research to support the potential benefits or lack thereof for normal and high supplementation with magnesium. Animal model research and early human trials are reviewed to document other disease states such as hypertension, cholesterol level, type 2 diabetes and cardiovascular disease that would benefit from increased magnesium.

Nutrition in Infancy: Volume 1

by Sherma Zibadi Ronald Ross Watson Victor R. Preedy George Grimble

Nutrition in Infancy: Volume 1 is a very useful resource for all clinicians treating and preventing nutritional problems in infants. This volume covers a wide range of topics that support wellness in infants through the prevention and treatment of infectious diseases, malnutrition, and developmental and genetic abnormalities. A variety of chapters deal with nutrients for infants with disabilities, surgery, and other special needs. <P><P> Special emphasis is provided for clinicians treating the millions of children in developing countries whose death is promoted by undernutrition or malnutrition. The next sections discuss the health benefits of supplementation and breast feeding and methods to improve use of berast feeding and it's duration. In Nutrition in Infancy: Volume 1, all of these facets of nutrition and nutritional therapy are covered in a precise and practical way. The latest developments in diagnostic procedures and nutritional support are also included. Written by a group of international experts, this volume is an indispensable new reference for clinicians with an interest in the nutrition and health of pregnant mothers and their infants.

Function-Oriented Bioengineered Skin Equivalents: Continuous Development Towards Complete Skin Replication (SpringerBriefs in Molecular Science)

by Tanja Zidarič Karin Stana Kleinschek Uroš Maver Tina Maver

The book Function-oriented bioengineered skin equivalents - continuous development towards complete skin replication aims to provide potential readers with a comprehensive summary of the available information on various in vitro skin models, from historical background to different modeling approaches and their applications. Particular emphasis is placed on presenting the current technological components available for the development of engineered skin equivalents by summarizing advances in cell cultivation, materials science, and bioengineering. Using examples of the current-state-of-art, we describe the advantages, limitations, and challenges of developing in vitro skin models for successful use in clinical applications and skin-related research.

Lean Done Right: Achieve and Maintain Reform in Your Healthcare Organization (ACHE Management)

by Thomas Zidel

Winner of the Axiom Business Book Award Silver Medal - Operations Management and Shingo Research and Professional Publication Award! Your healthcare organization cannot afford to waste time, money, or resources on an improper Lean implementation. You want to create a culture of continuous improvement, not a regime of tools that address problem areas but have short-lived results. Lean Done Right: Achieve and Maintain Reform in Your Healthcare Organization provides a roadmap for launching a transformative and sustainable Lean initiative. The Lean implementation model focuses on strategically directed action, developing a lean organizational culture, and enhancing the care delivery system. Chapters include: Death by Kaizen Event A Lean Implementation Model Strategically Directed Action The Culture-Creating Path Implement the Value Stream Work Plan The System-Creating Path Instructor Resources: PowerPoint slides of the exhibits from selected chapters.

Rethinking Lean in Healthcare: A Business Novel on How a Hospital Restored Quality Patient Care and Obtained Financial Stability Using Lean

by Thomas G. Zidel

This book deals with a hospital's struggle to secure and maintain financial stability. In the story, the leadership team of a fictional hospital adopts the tools and principles associated with the Toyota Production System or Lean. The story takes the reader through leadership's arduous journey from rejecting the methodology to embracing it, to successful implementation. This book is important because many of our nation's hospitals are besieged with financial difficulties with declining reimbursement and the public is losing confidence in our hospital's ability to provide quality care without error. Lean can provide relief from these issues but only if it is properly implemented.

Information and Communication Technologies for Ageing Well and e-Health: 6th International Conference, ICT4AWE 2020, Prague, Czech Republic, May 3–5, 2020, Revised Selected Papers (Communications in Computer and Information Science #1387)

by Martina Ziefle Nick Guldemond Leszek A. Maciaszek

This book constitutes the revised, selected and extended papers of the 6th International Conference on Communication Technologies for Ageing Well and e-Health, ICT4AWE 2020, held in Prague, Czech Republic, in May 2020. Due to the COVID-19 pandemic the conference was held online. The 7 full papers presented were carefully reviewed and selected from 50 submissions. The papers present most recent research on best practices, innovation and technical improvements in the fields of age and health care, education, psychology, social coordination and ambient assisted living.

Information and Communication Technologies for Ageing Well and e-Health: 5th International Conference, ICT4AWE 2019, Heraklion, Crete, Greece, May 2–4, 2019, Revised Selected Papers (Communications in Computer and Information Science #1219)

by Martina Ziefle Leszek A. Maciaszek

This book constitutes the thoroughly refereed proceedings of the third International Conference on Communication Technologies for Ageing Well and e-Health, ICT4AWE 2019, held in Heraklion, Crete, Greece in May 2019.The 9 full papers presented were carefully reviewed and selected from 52 submissions. The papers aim at contributing to the understanding of relevant trends of current research on ICT for Ageing Well and eHealth including the ambient assisted living.

Notfallmedizin

by Thomas Ziegenfuß

Dieses Lehrbuch bietet Ihnen einen vollständigen Überblick über alle prüfungsrelevanten Inhalte der Notfallmedizin. Es leitet Sie leicht verständlich von den Grundlagen bis zur Praxis durch das gesamte Wissen. Profitieren Sie von der langjährigen Erfahrung des Autors, der sorgfältig das Wesentliche für Sie ausgewählt und aufbereitet hat.Der InhaltDiese aktualisierte Neuauflage berücksichtigt die Leitlinien des European Resuscitation Council 2020. Zahlreiche Abbildungen und das bewährte didaktische Konzept ermöglichen ein effizientes Lernen:Prüfungsteil – Für eine optimale Vorbereitung auf FallstudienCave- und Merksätze – Bringen das Wichtigste auf den PunktPraxistipps – Stellen einen anschaulichen Bezug zur Notfallpraxis herDer AutorDr. Thomas Ziegenfuß ist Chefarzt der Abteilung für Anästhesie und Intensivmedizin des St. Josef-Krankenhauses in Moers. An der Klinik für Anästhesiologie und Intensivmedizin der Universitätskliniken des Saarlandes war er Oberarzt, langjähriger Einsatzleiter für den Notarztdienst und Leitender Notarzt.

Bio-Inspired Information Pathways: From Neuroscience to Neurotronics (Springer Series on Bio- and Neurosystems #16)

by Martin Ziegler Thomas Mussenbrock Hermann Kohlstedt

This open access book offers a timely and comprehensive review of the field of neurotronics. Gathering cutting-edge contributions from neuroscientists, biologists, psychologists, as well as physicists, microelectronics engineers and information scientists, it gives extensive information on fundamental information pathways in selected nervous systems. It also highlights their relevance as building blocks for novel computing architectures, such as bio-inspired electronic devices, neuromorphic architectures, memristive devices, adaptive sensors and emergent, pulsed-coupled oscillatory networks. All in all, this book offers a unique bridge between fundamental research in neuroscience, neural information processing, nonlinear dynamics, and self-organization, and advanced practical applications concerning the fabrication of hardware-oriented computing.

Handleiding medisch wetenschappelijk onderzoek

by G. A. Zielhuis P.H.J.M. Heydendael J. C. Maltha P.L.C.M. Riel

De moderne geneeskunde is in belangrijke mate gefundeerd op resultaten van medisch-wetenschappelijk onderzoek. Nieuwe inzichten in preventie, diagnose en prognose van ziekten kunnen alleen tot stand komen door degelijk uitgevoerd wetenschappelijk onderzoek. Evenzo kan de effectiviteit van een behandeling alleen door middel van goed onderzoek worden geëvalueerd. Kortom, medisch-wetenschappelijk onderzoek onderbouwt de toepassing van geneeskunde. Op basis van een 12-stappenplan biedt de Handleiding medisch-wetenschappelijk onderzoek de lezer een praktische handreiking bij de opzet en uitvoering van onderzoek. Een uitstekend hulpmiddel voor de: -arts(-assistent) die een wetenschappelijk artikel wil publiceren; -junior onderzoeker bij de aanvang van een onderzoek; -student die een scriptie of wetenschappelijk verslag wil schrijven; Deze achtste druk is geheel geactualiseerd. Er ligt nu meer nadruk op de context waarin het onderzoek plaatsvindt: wat is de relevantie voor mens en maatschappij, welke belangen zijn er, en hoe kan onderzoek integer en transparant blijven. Het aantal vormen van onderzoek is uitgebreid, o. a. met chirurgisch onderzoek, laboratoriumexperimenten, Big Data en data-gedreven studies. Actuele ontwikkelingen op het gebied van wetenschappelijke informatievoorziening, open access, organisatie en financiering en wetenschappelijke toetsing zijn verwerkt. Met moderne voorbeelden wordt ook de laboratoriumonderzoeker aangesproken. Het volledige boek is ook digitaal beschikbaar met samenvattingen en toetsvragen per hoofdstuk en interessante en verdiepende links.

Drugs for HER-2-positive Breast Cancer

by Christoph C. Zielinski Rupert Bartsch Thomas W. Grunt Maria Sibilia

Growth factor receptors have long been known to drive malignant transformation and cancer progression. The epidermal growth factor receptor (EGFR, ErbB, HER) system is likely the best described membrane receptor tyrosine kinase family in malignant tumors. With implementation of the growth-inhibitory anti-HER-2 antibody trastuzumab (Herceptin) for the treatment of HER-2-positive advanced metastatic breast cancer, a new era has dawned in the therapy of this malignant disease. Unfortunately, trastuzumab-sensitive cancers invariably develop resistance to the antibody after some time. Recent clinical studies have revealed that these refractory tumors are still responsive to inhibition of the HER receptor family using dual HER-1/-2 inhibitors such as lapatinib (Tykerb/Tyverb). Moreover, a multiplicity of novel, improved irreversibly acting small molecular HER tyrosine kinase inhibitors are in the pipeline of many drug developing companies and are being evaluated in the clinical setting.

The Acute Management of Surgical Disease

by Martin D. Zielinski Oscar Guillamondegui

Emergency General Surgery has become a cornerstone of Acute Care Surgery over the past decade. Once the scope of community general surgeons, the growing complexity of patients with acute surgical diseases has increasingly driven their care to tertiary referral centers. The aging population confounds this problem further as these patients present with more complex comorbidities, life-threatening physiology, and progressively severe anatomic disease severity. To ensure better outcomes, the practice has evolved to focus on evidence-based practice management guidelines in order to standardize care and optimize outcomes.The purpose of this text is to be a comprehensive volume for patients with acute surgical diseases. There will be three sections, each comprised of multiple chapters. The first section will be a comprehensive analysis of the background of Emergency General Surgery. The goal of this section will be to provide the reader background into the acute surgical practice and to introduce the reader to the important concepts discussed in the remainder of the textbook. The second section will be the largest and will discuss specific acute surgical diseases. Individual chapters will outline the diagnostic approach, current treatment standards, operative approaches, and expected outcomes with an emphasis on practice management guideline implementation into practice. As acute surgical diseases and surgical critical care are integral to each other, the last section will be Critical Care for the Acute Care Surgeon. These topics will focus on the critical care concepts essential to surgeons who care for acute diseases.This comprehensive text is targeted to any surgeon who takes emergency call for any of the listed diseases including community and referral general and vascular surgeons. In addition, this would be an excellent resource for all general surgery residents. Lastly, this would also serve as a resource to intensivists who care for acute surgical patients.

The Transcervical Approach in Thoracic Surgery

by Marcin Zieliński Ramón Rami-Porta

Use of the transcervical approach in thoracic surgery has advanced significantly during the past 60 years, owing primarily to advances in technology. Nevertheless, the possibilities of this approach have never been compiled in a systematic way. This book aims to rectify the situation by describing, in a structured way, all the thoracic procedures that can be performed using the transcervical approach. Indications and contraindications, surgical techniques, complications, and results are all covered, based on the authors' experience and published reports. The contents encompass diverse surgical endoscopic procedures for diagnosis and staging, use of the transcervical approach for surgery to the thymus and mediastinum, lungs and bronchi, trachea and esophagus and miscellaneous items including the role of robotic surgery.

Genotype Phenotype Coupling: Methods and Protocols (Methods in Molecular Biology #2070)

by Stefan Zielonka Simon Krah

This volume aims at providing state-of-the-art protocols detailing ribosome display, cDNA display, phage display, yeast surface display, and mammalian display. Chapters guide readers through methods and protocols on in vitro methods over prokaryotic display systems, lower eukaryotes, and mammalian cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of all necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Genotype Phenotype Coupling aims to provide an overview of current technologies in this exciting and continuously evolving field.

Cardiac Surgery: Operations on the Heart and Great Vessels in Adults and Children

by Gerhard Ziemer Axel Haverich

This text describes and illustrates with some 700 detailed anatomic and surgical drawings the whole spectrum of surgical procedures employed to treat acquired and congenital diseases of the heart and great vessels in adults and children.A rather traditional chapter on history of cardiac surgery precedes chapters dedicated to quality improvement, followed by ICU management in adult and pediatric cardiac surgery, and techniques of extracorporeal circulation in both age groups.Further special topics are cardiovascular tissue engineering, minimally invasive cardiac surgery, endovascular treatment of aortic diseases, and cardiac assist devices, including total artificial heart.Written by 71 internationally recognized experts from 40 cardiac units in Central Europe and North America, this book will be invaluable not only for both novice and experienced surgeons, but also for all physicians, nurses, and technicians caring for patients with heart disease of any type, at any age.

Atlas of Whole Body Contouring: A Practical Guide

by Richard J. Zienowicz Ercan Karacaoglu

This atlas presents current and proven strategies and techniques for body contouring in plastic and reconstructive surgery. In the majority of plastic surgeries, and likewise in body contouring surgeries, surgeons don't have the luxury of long learning curves. The book's simple, descriptive, and didactic structure addresses this issue. The topics have been carefully selected to avoid redundancies and, where there is more than one surgical option to choose from, expert contributors present the technique that has been broadly accepted as ‘the procedure of choice’. The easily accessible information will guide surgeons in their daily practice, helping them minimize complications and achieve consistent results. The book also presents a number of complicated cases, supported by descriptive figures and high-quality illustrations, offering a unique resource for plastic surgeons around the globe.

Ethical Issues in Cardiovascular Medicine (Routledge Annals of Bioethics)

by David M. Zientek Mark J. Cherry

This book provides an exploration of the ethics of cardiology practice. It provides a variety of frameworks for analyzing ethical issues that arise in cardiovascular medicine. Cardiovascular medicine—the diagnosis and treatment of congenital and acquired diseases of the heart, major arteries, and veins—has seen rapid change in diagnosis, treatment, and the organization of practice in the last half of the twentieth and the beginning of the twenty first century. The complexity of these developments has resulted in increasing subspecialization, and many practitioners are challenged to stay abreast with the latest developments in cardiology. These changes also bring with them various ethical challenges. The chapters in this volume are divided by five broad areas of practice: beginning-of-life, end-of-life, transplantation and allocation of expensive or scarce resources, professionalism, and research. The case-based approach presented across the volume provides a perspective that will allow readers to reason through current and future ethical issues as they arise in this rapidly changing field. Ethical Issues in Cardiovascular Medicine will be of interest to researchers working in bioethics, clinical ethics, and the philosophy of medicine, as well as practicing physicians, nurses, and students who work in cardiovascular medicine.

Muscle Metabolism

by Juleen R. Zierath Harriet Wallberg-Henriksson

Diabetes research on models comprising intact animal tissues, cell cultures and isolated pancreatic islets is essential for understanding the pathogenesis of the disease as well as the mechanisms responsible for the chronic complications associated with it. Enormous advances in the understanding of the development of diabetes and its prevention hav

Intraocular Inflammation

by Manfred Zierhut Carlos Pavesio Shigeaki Ohno Fernando Oréfice Narsing A. Rao

This well-structured and lavishly illustrated book is a comprehensive reference on intraocular inflammation that encompasses all anatomic forms, settings and etiologies. Individual sections are devoted to uveitis associated with systemic disorders, uveitis syndromes restricted to the eye, bacterial uveitis, viral uveitis, fungal uveitis, parasitic uveitis, uveitis caused by other microbes, traumatic uveitis, and masquerade syndromes. Chapters on the different forms of uveitis are in a homogeneous reader-friendly format, with identification of core messages, explanation of etiology and pathogenesis, up-to-date information on diagnostics and differential diagnosis and guidance on the most appropriate forms of treatment and prognosis. Helpful flow charts are included to assist in identification of potential underlying disorders and the reader will also have online access to one hundred informative case reports demonstrating the different courses of intraocular inflammation. The authors are world experts keen to share their vast experience with the reader. Intraocular Inflammation will be a valuable resource for all physicians who deal with patients with inflammatory eye disease.

Musikermedizin in der Physiotherapie und Ergotherapie: Befund und Behandlung spielbedingter Beschwerden

by Clemens Ziesenitz

In diesem Buch werden die theoretischen Grundlagen der Musikermedizin sowie die besonderen Anforderungen und Belastungen von professionellen Musikerinnen und Musikern praxisorientiert vermittelt. Der herausfordernde Berufsalltag kann durch die asymmetrische Haltung, der statischen Beanspruchung am Instrument oder durch langanhaltende, repetitive Bewegungsabfolgen zu muskulären Dysbalancen oder Überlastungssyndromen führen. Der Autor beschreibt anhand häufiger Störungsbilder die Befunderhebung und Behandlung in der Physiotherapie und Ergotherapie Das Praxisbuch erweitert das Wissen auf diesem spezialisierten Gebiet und hilft dabei, Musikerinnen und Musiker bestmöglich zu unterstützen, um typische Beschwerden vorzubeugen und ihre Leistungsfähigkeit zu steigern.

Parietale Osteopathie: Über 60 Übungen für Automobilisation und Kräftigung

by Clemens Ziesenitz

Dieses Praxisbuch liefert Osteopathen und Physiotherapeuten Übungen für Patienten zur Automobilisation von Gelenkdysfunktionen und ergänzende Kräftigung für die stabilisierende Muskulatur. Sie suchen nach Übungsalternativen in verschiedenen Ausgangsstellungen? Sie fragen sich, was bei der Mobilisation der ersten Rippe mit Hilfe der Mm. Scaleni zu beachten ist? Oder ob sich die Greenman-Technik zur Behandlung einer ERS der Halswirbelsäule eignet? In diesem Buch werden Sie fündig!Aus dem Inhalt:• Grundlagen der Schmerzphysiologie• Automobilisation für Dysfunktionen an Becken, Wirbelsäule und Rippengelenken• Integrierende Stabilisationsübungen• Indikationen, KontraindikationenPlus: Videos via Springer Nature MoreMedia-App und Handouts für Patienten!Erweitern Sie Ihr Behandlungsrepertoire um über 60 effektive Eigenübungen, die Ihre Patienten ohne viel Aufwand in den Alltag integrieren können!

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