- Table View
- List View
Statistical Approaches for Epidemiology: From Concept to Application
by Amal K. MitraThis textbook provides the basic concepts of epidemiology while preparing readers with the skills of applying statistical tools in real-life situations. Students, in general, struggle with statistical theories and their practical applications. This book makes statistical concepts easy to understand by focusing on real-life examples, case studies, and exercises. It also provides step-by-step guides for data analysis and interpretation using standard statistical software such as SPSS, SAS, R, Python, and GIS as appropriate, illustrating the concepts.Through the book's 23 chapters, readers primarily learn how to apply statistical methods in epidemiological studies and problem-solving. Among the topics covered:Clinical TrialsEpidemic Investigation and ControlGeospatial Applications in EpidemiologySurvival Analysis and Applications Using SAS and SPSSSystematic Review and Meta-Analysis: Evidence-based Decision-Making in Public HealthMissing Data Imputation: A Practical Guide Artificial Intelligence and Machine LearningMultivariate Linear Regression and Logistics Regression Analysis Using SASEach chapter is written by eminent scientists and experts worldwide, including contributors from institutions in the United States, Canada, Bangladesh, India, Hong Kong, Malaysia, and the Middle East. Statistical Approaches for Epidemiology: From Concept to Application is an all-in-one book that serves as an essential text for graduate students, faculty, instructors, and researchers in public health and other branches of health sciences, as well as a useful resource for health researchers in industry, public health and health department professionals, health practitioners, and health research organizations and non-governmental organizations. The book also will be helpful for graduate students and faculty in related disciplines such as data science, nursing, social work, environmental health, occupational health, computer science, statistics, and biology.
Statistical Methods in Epilepsy (Chapman & Hall/CRC Interdisciplinary Statistics)
by Sharon Chiang Vikram R. Rao Marina VannucciEpilepsy research promises new treatments and insights into brain function, but statistics and machine learning are paramount for extracting meaning from data and enabling discovery. Statistical Methods in Epilepsy provides a comprehensive introduction to statistical methods used in epilepsy research. Written in a clear, accessible style by leading authorities, this textbook demystifies introductory and advanced statistical methods, providing a practical roadmap that will be invaluable for learners and experts alike.Topics include a primer on version control and coding, pre-processing of imaging and electrophysiological data, hypothesis testing, generalized linear models, survival analysis, network analysis, time-series analysis, spectral analysis, spatial statistics, unsupervised and supervised learning, natural language processing, prospective trial design, pharmacokinetic and pharmacodynamic modeling, and randomized clinical trials.Features: Provides a comprehensive introduction to statistical methods employed in epilepsy research Divided into four parts: Basic Processing Methods for Data Analysis; Statistical Models for Epilepsy Data Types; Machine Learning Methods; and Clinical Studies Covers methodological and practical aspects, as well as worked-out examples with R and Python code provided in the online supplement Includes contributions by experts in the field The handbook targets clinicians, graduate students, medical students, and researchers who seek to conduct quantitative epilepsy research. The topics covered extend broadly to quantitative research in other neurological specialties and provide a valuable reference for the field of neurology.
Statistics for Nursing: A Practical Approach
by Elizabeth HeaveyNurses are leveraging new technologies to interpret and analyze clinical data. Understanding how to use that information and make appropriate clinical decisions are vital to their role and proper patient care. Statistics for Nursing: A Practical Approach, Fourth Edition presents the complicated topic of statistics in an understandable manner, so students are prepared to start their career no matter the setting. Relevant clinical examples followed by end of chapter application exercises, provide students the opportunity to practice statistics while learning. The Fourth Edition introduces Intellectus Statistics, a web-based statistical software program designed to help non-statisticians learn to conduct research and complete statistical analyses appropriately. Often, computer applications are the most stressful part of learning statistics. This program simplifies the process of learning the software while helping students produce and understand the actual statistics content.
Staying Human during Residency Training: How to Survive and Thrive after Medical School, Seventh Edition
by Allan D. Peterkin, MD Derek Puddester, MDThe ultimate survival guide for medical students, interns, residents, and fellows, Staying Human during Residency Training provides time-tested advice and the latest information on every aspect of a resident’s life – from choosing a residency program to coping with stress, enhancing self-care, and protecting personal and professional relationships. The book features hundreds of tips on how to cope with sleep deprivation, time pressures, and ethical and legal issues. Updated to reflect the latest research and resources, the seventh edition provides new emphasis on virtual practice, gender, diversity, and accountability in the context of medical education.. It offers practical strategies learned from new technologies and new insight on the COVID-19 pandemic regarding public health, virtual appointment protocols, and AI developments. Presenting practical antidotes regarding cynicism, careerism, and burnout, the book also offers guidance on fostering more empathic connections with patients and deepening relationships with colleagues, friends, and family. Acknowledged by thousands of doctors across North America as an invaluable resource, Staying Human during Residency Training has helped to shape notions of trainee well-being for medical educators worldwide. Offering wise, compassionate, and professional counsel, this new edition again shows why it is required reading for medical students and new physicians pursuing postgraduate training.
Stem Cell and Tissue Engineering: Bone, Cartilage, and Associated Joint Tissue Defects
by Krishna PramanikThis book covers conventional clinical treatment methods for handling bone, cartilage, and related disorders along with their limitations and highlights the current state of the art of tissue engineering as an alternative for regenerating such defective tissue. Potential biomimetic scaffolding materials and their development, desired properties, modifications, and optimizations are described. The design and advancement in fabrication, characterization, properties, and biological functions of scaffolds, their integration with stem cells, and various bioreactor systems for tissue regeneration are presented. It further reviews in vitro and in vivo (pre-clinical) assessments of tissue constructs, involved translational challenges, and strategies in various stages of neo-tissue production.Features: Discusses the key aspects of generating engineered bone, cartilage, and associated tissues through tissue engineering approach Describes multiple engineering principles, and processes involved in the various stages of developing biomaterials and scaffolds Covers integration of stem cells with scaffolds, including assessment of tissue grafts, and translational strategy Explores key factors influencing tissue graft generation in bioreactors and challenges involved in various stages Includes several exercises including review questions and numerical problems for better understanding of the subject This book is aimed at researchers, students, and professionals in biomedical engineering, tissue engineering, stem cells, biomaterials, and orthopaedics.
Step-Up to Medicine (Step-Up Series)
by Steven Agabegi Elizabeth D. AgabegiMake the most of your study time and confidently take the next step in your medical career with this bestselling review. Step-Up to Medicine, 6th Edition, makes it easy to find information fast and take a confident next step toward a successful medical career. Ideal for preparing for clerkships or clinical rotations, shelf exams, and the USMLE Step 2, this bestselling volume in the popular Step-Up series provides a high-yield review of medicine in a concise, comprehensive approach. This 6th Edition is thoroughly updated and enhanced throughout. Clinical pearls, full-color illustrations, and “Quick Hits” provide essential information in an efficient, easy-to-remember manner to ensure excellence on exams and confidence in clinical settings, and a 100-question practice exam reinforces exam readiness and boosts test-taking confidence.
Storytelling in Medicine: How narrative can improve practice
by Colin Robertson, Gareth Clegg, James HuntleyThroughout our lives, story is the medium each of us uses to make sense of our environment and relationships. Stories provide meaning and context, enriching our experiences and equipping us with a framework to navigate our existence. This unique, practical book for healthcare trainees, practitioners and educators explores the ideas and practice of narrative and storytelling that lie at the very heart of clinical medicine and the patient ‘experience’ of care. It shows how story and narrative can be used effectively to help convey concepts such as prognosis and the effect of illness upon life, and to prepare patients and their relatives for difficult and painful news. Offering a particular insight into communication by and between healthcare professionals, and how it can be refocused and improved, this updated and expanded second edition remains an invaluable teaching aid for educators working in both small and large formats, and for under- and postgraduate students.
Stroke Genetics
by Pankaj Sharma James F. MeschiaThis revised, expanded third edition updates the reader on this fast moving field as well providing an overall understanding of the genetics of complex diseases by using stroke as a paradigm. The reader will gain a comprehensive understanding of cerebrovascular genetics including the epidemiological evidence for the genetic basis of ischemic and hemorrhagic stroke, knowledge of its molecular basis from association, linkage and recent genome-wide studies, and also monogenic disorders. Finally, the legal and ethical complexities in dealing with these issues are discussed.Stroke Genetics is a valuable resource for neurologists, stroke physicians, hypertension specialists, internists, clinical pharmacologists and those in training, as well as researchers in the field of disease genetics. Each chapter now contains teaching/training MCQs to help with retention of information learnt from each chapter and this will be of considerable use to those training or about to the examined inthe field of inherited stroke.Additional questions via app: Download the Springer Nature Flashcards app for free and use exclusive additional material to test your knowledge.
Study Guide for Jones & Bartlett Learning's Comprehensive Medical Assisting
by Judy Kronenberger Julie LedbetterMaster your course with the practice and hands-on-activities that will help you get ready for the medical office. In this new edition of Study Guide for Jones & Bartlett Learning's Comprehensive Medical Assisting, the exercises and activities align with the most current Medical Assisting Education Review Board (MAERB) of the American Association of Medical Assistants (AAMA) curriculum standards. The Study Guide is divided into sections that coincide with the textbook and includes exercises that reinforce the knowledge and skills required of all Medical Assistants.
“Successful Aging”?: Leitbilder des Alterns in der Diskussion (Altern & Gesellschaft)
by Larissa Pfaller Mark SchwedaDer vorliegende Band versammelt zentrale Perspektiven der deutschsprachigen Alternsforschung auf Successful Aging. Ziel ist es, die wissenschaftliche Begründung, gesellschaftliche Bedeutung, moralische Akzeptabilität und politische Legitimität zeitgenössischer Leitbilder des Alter(n)s kritisch unter die Lupe zu nehmen. Dabei beleuchten die Beiträge insbesondere, welche Verständnisse des Alter(n)s den verschiedenen Ansätzen und Spielarten gelingenden Alterns zugrunde liegen, welche Leitbilder mit ihnen Einzug in wissenschaftliche Debatten und politische Auseinandersetzungen halten und in welcher Beziehung sie zu alltagsweltlichen Erfahrungen älterer Menschen sowie zu philosophisch-ethischen Theorien eines guten Lebens im Alter stehen.
Sun Seekers: A Novel
by Rachel McRadyFrom Emmy Award-winning writer Rachel McRady comes a vital, illuminating debut novel of a broken family uniting in the face of terrifying crisis, for fans of This is Us and Parenthood.Six-year-old Gracie Lynn is perpetually curious and big-hearted. Convinced she knows how to save her beloved grandfather John from the &“worm&” that is eating his brain—a metaphor her mother once used to explain John&’s dementia and sundown syndrome—she helps him break out of his nursing home, and the two disappear together on a quest to chase the sun. But what&’s an adventure for Gracie is a nightmare scenario for her estranged parents, LeeAnn and Dan. There&’s no way to predict where John might have taken their young daughter, or if he&’s capable of keeping her safe.Jaded beyond her years, and struggling with her own mental health, LeeAnn has no delusions about what might happen if they don&’t locate Gracie soon. Dan is no less frantic, but communicating with LeeAnn isn&’t easy, even under the circumstances—too much stands between the hopeful young couple they once were and the people they&’ve become.An emotionally resonant novel for fans of Fredrik Backman and Mark Haddon, Sun Seekers artfully explores the truths of parenthood, the ways in which we sometimes hurt those we love most, and the universal experience of deep loss—even when the person is still here.
Super-Resolution Microscopy for Material Science
by Lorenzo Albertazzi Peter ZijlstraOptical microscopy is one of the most frequently used tools in chemistry and the life sciences. However, its limited resolution hampers the use of optical imaging to many other relevant problems in different disciplines. Super-Resolution Microscopy (SRM) is a new technique that allows the resolution of objects down to a few billionth of meters (nanometers), ten times better than classical microscopes, opening up opportunities to use this tool in new fields.This book describes the theory, principles, and practice of super-resolution microscopy in the field of materials science and nanotechnology. There is a growing interest in the applications of SRM beyond biology as new synthetic materials, such as nanoscale sensors and catalysts, nanostructured materials, functional polymers, and nanoparticles, have nanoscopic features that are challenging to visualize with traditional imaging methods.SRM has the potential to be used to image and understand these cutting-edge man-made objects and guide the design of materials for novel applications.This book is an ideal guide for researchers in the fields of microscopy and materials science and chemistry as well as graduate students studying physics, materials science, biomedical engineering, and chemistry.Key Features: Contains practical guidance on Super-Resolution Microscopy (SRM), an exciting and growing tool that was awarded the Nobel Prize for chemistry in 2014 Provides a new perspective targeting materials science, unlike existing books which target readers in chemistry, life science, and biology Targets students in its core chapters, while offering more advanced material for professionals and researchers in later chapters
Supervised and Unsupervised Data Engineering for Multimedia Data
by Suman Kumar Swarnkar J P Patra Sapna Singh Kshatri Yogesh Kumar Rathore Tien Anh TranSUPERVISED and UNSUPERVISED DATA ENGINEERING for MULTIMEDIA DATA Explore the cutting-edge realms of data engineering in multimedia with Supervised and Unsupervised Data Engineering for Multimedia Data, where expert contributors delve into innovative methodologies, offering invaluable insights to empower both novices and seasoned professionals in mastering the art of manipulating multimedia data with precision and efficiency. Supervised and Unsupervised Data Engineering for Multimedia Data presents a groundbreaking exploration into the intricacies of handling multimedia data through the lenses of both supervised and unsupervised data engineering. Authored by a team of accomplished experts in the field, this comprehensive volume serves as a go-to resource for data scientists, computer scientists, and researchers seeking a profound understanding of cutting-edge methodologies. The book seamlessly integrates theoretical foundations with practical applications, offering a cohesive framework for navigating the complexities of multimedia data. Readers will delve into a spectrum of topics, including artificial intelligence, machine learning, and data analysis, all tailored to the challenges and opportunities presented by multimedia datasets. From foundational principles to advanced techniques, each chapter provides valuable insights, making this book an essential guide for academia and industry professionals alike. Whether you’re a seasoned practitioner or a newcomer to the field, Supervised and Unsupervised Data Engineering for Multimedia Data illuminates the path toward mastery in manipulating and extracting meaningful insights from multimedia data in the modern age.
Supporting Survivors of Sexual Violence and Abuse: Approaches to Care for Health Professionals
by Claire Dosdale Emma Senior Lynette Shotton Katy SkarparisThis textbook provides practical guidance to enable health professionals to support survivors of sexual violence. It gives insight into the complex and wide-ranging nature and experience of sexual violence, barriers to disclosure, and explores the implications for survivors, health professionals and healthcare organisations.An evidence-based resource, this book provides information, guidance and signposting for all those who might receive disclosures of sexual violence, challenging perceptions, stigma and judgement. As well as discussing disclosure of recent experiences, it takes into account that life events may trigger the re-surfacing of prior experiences. The book also operates as a practical tool, prompting professionals to reflect on their own clinical experience of dealing with disclosures of sexual violence. The chapters look at the full breadth of sexual violence and abuse, including rape and sexual assault, child sexual abuse, harassment and stalking, exploitation, trafficking, conflict situations, traditional practices and sexual violence in LGBTQAI+ communitites.Enabling readers to develop the necessary knowledge and understanding to inform their practice, this book is a comprehensive resource for all health professionals, across primary and secondary care. It is also a valuable text for those taking post-registration courses in sexual health, specialist community and public health nursing, district nursing, mental health and children’s nursing among others. Reflection sections can be used to support professional registration revalidation.
Supportive Smart Homes: Their Role in Aging in Place (Synthesis Lectures on Technology and Health)
by Frank Knoefel Bruce Wallace Neil Thomas Heidi Sveistrup Rafik Goubran Christine L. LaurinSignificant health-industry human resource needs increase the reliance on family and friends to support older adults hoping to age in place. This book explores how recent improvements in integrated home technologies have the potential to address those challenges. The book considers how embedded home sensors can be used to monitor the health and wellbeing of older adults and how that can be used to assist with supporting safety and well-being. The content is designed to help multiple stakeholders in the supportive smart home space to better understand the complexity of this field and the need for transdisciplinary collaboration. These stakeholders include the older adults who will benefit from supportive smart home technology; informal and formal caregiver and healthcare professionals concerned about the older adult’s well-being; researchers from multiple disciplines in the supportive smart home area and their funders; companies looking to develop solutions and services or expand their offerings; policy makers who want to ensure privacy and equity in access and a successful integration of these technologies into the evolving health and social services sectors; and students, the future leaders in AgeTech. Overall, the intent of the book is to inspire engineers, computer scientists, industrial designers, clinicians and healthcare providers, social scientists, students, policy makers, and older adults and their caregivers to collaborate in advancing the supportive smart home space to develop more options for aging in place.
Surface Engineering of Biomaterials: Synthesis and Processing Techniques (Emerging Materials and Technologies)
by Ajit Behera Debasis Nayak Biswajit Kumar SwainSurface engineering provides one of the most important means of engineering product differentiation in terms of quality, performance, and lifecycle cost. It is essential to achieve predetermined functional properties of materials such as mechanical strength, biocompatibility, corrosion resistance, wear resistance, and heat and oxidation resistance. Surface Engineering of Biomaterials addresses this topic across a diverse range of process technologies and healthcare applications. Introduces biomaterial surface science and surface engineering and includes criteria for biomaterial surface selection Focuses on a broad array of materials including metals, ceramics, polymers, alloys, and composites Discusses corrosion, degradation, and material release issues in implant materials Covers various processing routes to develop biomaterial surfaces, including for smart and energy applications Details techniques for post-modification of biomaterial surfaces This reference work helps researchers working at the intersection of materials science and biotechnology to engineer functional biomaterials for a variety of applications.
Surgery for Osteoporotic Fractures
by Frankie Leung Tak Wing LauThis book introduces recent advances in implants and surgical techniques for osteoporotic fractures. It covers most frequent fractures especially in the geriatric population, such as fractures of the hip, distal radius, proximal humerus, peri-prosthetic fractures and drug associated atypical femoral fractures, etc. The book details special surgical techniques which are required to treat these challenging and complex fractures. It also covers the current concept of geriatric fracture care and encompasses the holistic management of these patients from surgical management of the fracture to rehabilitation and prevention of subsequent fragility fractures.
Surgery of Craniosynostosis and Related Midface Deformities: An Atlas and Step-by-Step Guide
by Michael RasseThis atlas offers a comprehensive overview of osteotomies performed on the calvaria and midface for both syndromic and non-syndromic craniosynostosis.It presents a systematic approach, beginning with calvarial osteotomies. The author introduces a general type of osteotomy that can be applied for total vault remodeling in cases of total synostosis. These osteotomies can also be modified and used in single or combined synostoses. To shape the calvaria, the book describes the use of metal plates as a scaphold. These plates can be prebent on 3-D models and used to fix the segments after osteotomies. Following that, resorbable osteosynthesis is performed, and the metal plates are subsequently removed. This unique approach, combined with standardized osteotomies, ensures highly predictable results that are not currently described in textbooks. The book includes clinical examples for each type of synostosis and various combinations, including two-stage procedures and combinations with distraction techniques. These examples provide surgeons with a solid foundation for addressing different cases. In the chapter on midface osteotomies, the book explains the access and technique for performing the LeFort-III osteotomy using cadaver and clinical figures. It covers all types of LeFort-I to III osteotomies and their combinations through clinical cases. The book illustrates the osteotomies, osteosynthesis, distraction techniques, and combinations using clinical examples. Additionally, the book demonstrates the method of computer planning, the fabrication of osteotomy guides, and the use of preformed plates to define the position of the segments.The book's primary objective is to serve as a surgical guide that transcends the boundaries of medical specialties. Given that this type of surgery is often performed by different specialists across institutions and countries, the book aims to facilitate cooperation and provide a practical application tool for surgeons beyond offering a clinical overview.
Surgical Neuro-Oncology: In Multiple Choice Questions
by Samer S. Hoz Oday Atallah Li Ma Zaid Aljuboori Mayur Sharma Mustafa Ismail Maliya DelawanThis book is the first review book that uses the multiple-choice question format in neurosurgical oncology which mirrors the format of the majority of shelf and board examinations.The mission of the book is to help readers understand the content and maintain the knowledge, rather than merely finding answers for complicated questions. It provides more than 800 MCQs in a convenient format that is suitable for self-study. Answers and definitions appear immediately below the questions to facilitate information retention. The chapters provide comprehensive coverage of the core concepts in neurosurgical oncology. They provide a step-by-step, thorough explanations of each disease from the definition, associated anatomy, pathology, clinical features, radiology to surgical decision-making, and surgical tricks, providing a comprehensive and concise overview.This book is an adjunct to the existing texts and does not intend to be the primary source of information; it ratheraims to help readers identify their relevant strengths and weaknesses in the area. The book is an important asset for residents across neurosurgical disciplines as it includes much of the neuro-oncology knowledge that neurosurgical residents need to prepare for their certification tests. It is also useful for those seeking ways to solidify their knowledge or maintain their current certification.
Surgical Patient Care for Veterinary Technicians and Nurses
by Gerianne Holzman Teri Raffel KleistSurgical Patient Care for Veterinary Technicians and Nurses A step-by-step guide to caring for small animal surgical patients Surgical Patient Care for Veterinary Technicians and Nurses, Second Edition offers a complete, practical guide to nursing care for patients undergoing common and advanced surgeries in small animal practice. Written by veterinary technicians for veterinary technicians, the book is organized chronologically, beginning with the initial client contact and continuing through surgery to discharge and aftercare. The new edition significantly expands the surgical procedures chapter, adding new procedures, and incorporates updates to reflect new knowledge throughout. Topics cover all aspects of surgical patient care, including surgical assisting and patient comfort, for orthopedic, soft tissue, and emergency surgeries. A companion website offers video clips and review questions and answers, plus the figures from the book in PowerPoint. The Second Edition features: Hundreds of clinical photographs to support the text, with more than 100 images new to this edition, including many new instrument photos A logical chronological organization, from initial client communication through to discharge and aftercare instructions Topics ranging from laboratory testing, patient preparation, and instrument care and maintenance to bandaging, client communication, rehabilitation, encompassing orthopedic, ophthalmic, soft tissue, and emergency surgeries Expanded coverage of surgical procedures and wound management A companion website with video clips, review questions and answers, and the figures from the book in PowerPoint Surgical Patient Care for Veterinary Technicians and Nurses is equally useful for veterinary technician and nursing students and for veterinary technicians and nurses in practice, providing practical advice in a well-illustrated format.
Surviving Alex: A Mother’s Story of Love, Loss, and Addiction
by Patricia A. RoosIn 2015, Patricia Roos’s twenty-five-year-old son Alex died of a heroin overdose. Turning her grief into action, Roos, a professor of sociology at Rutgers University, began to research the social factors and institutional failures that contributed to his death. Surviving Alex tells her moving story—and outlines the possibilities of a more compassionate and effective approach to addiction treatment. Weaving together a personal narrative and a sociological perspective, Surviving Alex movingly describes how even children from “good families” fall prey to addiction, and recounts the hellish toll it takes on families. Drawing from interviews with Alex’s friends, family members, therapists, teachers, and police officers—as well as files from his stays in hospitals, rehab facilities, and jails—Roos paints a compelling portrait of a young man whose life veered between happiness, anxiety, success, and despair. And as she explores how a punitive system failed her son, she calls for a community of action that would improve care for substance users and reduce addiction, realigning public health policy to address the overdose crisis.
Sustainable Approaches in Pharmaceutical Sciences
by Kamal Shah Durgesh Nandini Chauhan Nagendra Singh ChauhanHighly comprehensive and detailed text on best possible sustainable approaches associated with the development, design, and origination of pharmaceuticals Sustainable Approaches in Pharmaceutical Sciences enables readers to understand the best possible green approaches associated with the development, design, and origination of pharmaceuticals, including resources that may minimize the adverse effects associated with synthesis, isolation, and extraction. Sustainable Approaches in Pharmaceutical Sciences covers a myriad of current topics, including mechanochemical improvements for API synthesis, as well as the role of artificial intelligence (AI) in the development and discovery of pharmaceuticals, along with recent developments in hydrogels which respond to triggered factors during topical drug delivery. Authored by experienced scientists from institutions across the world, other sample topics covered in Sustainable Approaches in Pharmaceutical Sciences include: Green technologies and benefits associated with them, white biotechnology, green chemistry, and eco-friendly approaches for designing active pharmaceutical ingredients Impact of sustainable approaches in pharmaceutical industries regarding use of solvents, nanoparticles formulations, and antimicrobial bandages Micro-extractive methods capable of generating high recovery values of the analytes and associated techniques, such as dispersive liquid-liquid microextraction Benefits of the exploration of sustainable chemistry on a commercial scale, particularly in relation to bioresources, chemical manufacturing, and organic transformationDiscussing both the foundational science and practicality of different approaches regarding human and environmental health, Sustainable Approaches in Pharmaceutical Sciences is an essential resource for scientists, medical professionals, and industrial professionals working in the fields of sustainable technology and synthesis in pharmaceutical sciences, along with advanced level students.
Synbiotics in Human Health: Biology to Drug Delivery
by Kamal DuaThis reference book discusses the role of synbiotics in a wide range of disease states, including cardiovascular, reproductive, metabolic, neurodegenerative, gastrointestinal, thrombotic, skin, and inflammatory disorders. It reviews the functions of probiotics in the diagnosis, prevention, or treatment of various disease states. The book further covers improving the targeting efficiency of synbiotics through advanced drug delivery systems such as nanoparticles, microparticles, liposomes, microemulsion, solid lipid nanoparticles, and nano lipid carriers. The chapter addresses the implications of oral and topical delivery of synbiotics in different diseases and presents the safety assessment of synbiotics and clinical trials associated with synbiotics containing drug delivery systems for the treatment of diseases. The book also explores the synergistic welfare of synbiotics nutraceuticals in various conditions such as chronic respiratory diseases, gut health, and neurological functions and examines the toxicological profile, and regulatory aspects of nutraceutical supplements. As such, this book is a valuable resource for academics, research and industry professionals working in Pharmaceutical Sciences, Food Biotechnology, Immunology, and Health Sciences.
Synthesis of Medium-Sized Cycloalkenes via Fused-Cyclobutenes (Springer Theses)
by Tomohiro ItoThis book explains the existence of the intermediate using two approaches: computational chemistry and coordination chemistry. In this book, the author has developed new methods for synthesizing medium-sized cycloalkenes by utilizing the 4π-electrocyclic reaction of fused-cyclobutenes. The fundamental and most important strategy and feature of the work are as follows: first, cyclobutene is used as a readily available raw material with high-strain energy to generate more strained medium-sized cis,trans-cycloalkadiene molecules. Second, by judiciously selecting the reaction conditions, the short-lived intermediate (medium-sized cis,trans-cycloalkadiene) can be converted to medium-sized cis- or trans-cycloalkenes. For the former, the generation of the medium-sized cis,trans-cycloalkadiene intermediate is greatly affected by the substituent on the cyclobutene, and there are few examples of its generation confirmed at room temperature. Regarding the latter, the synthesis of trans-cycloalkenes is noteworthy in terms of establishing a new synthetic methodology and providing one of the few asymmetric synthesis methods, which has not been achieved before. Readers of this book can gain novel insights into strained molecules involved not only in small-sized cycloalkenes but also in medium-sized ones.
A Systemic Approach to Behavioral Healthcare Integration: Context Matters (Fundamentals of Clinical Practice With Couples and Families Series)
by Dr. Nancy Breen Ruddy PhD Dr. Susan H. McDanielThis book provides clinicians, consultants, and healthcare administrators with a roadmap to establishing a systemic, patient-centered, family-oriented behavioral health service that is integrated into a healthcare setting. Healthcare that goes beyond biomedical issues to address our whole biopsychosocial selves, produces better outcomes for patients and families. Integrating behavioral health into medical settings requires an understanding of the interplay of multiple systemic layers in American healthcare. The existing literature on integration largely fails to address the "big picture" of integrated services and systems, including operations, clinical processes, and financial sustainability elements.A Systemic Approach to Behavioral Healthcare Integration summarizes the literature on the impact of integrating behavioral health care into medical settings, on the role of families in health maintenance and chronic disease management, and on team science and applying family systems theory/relational science to the teams that are now essential to healthcare.