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A Shot to Save the World: The Inside Story of the Life-or-Death Race for a COVID-19 Vaccine

by Gregory Zuckerman

"An inspiring and informative page-turner." –Walter IsaacsonLonglisted for the FT/McKinsey Business Book of the Year Award The authoritative account of the race to produce the vaccines that are saving us all, from the #1 New York Times bestselling author of The Man Who Solved the MarketFew were ready when a mysterious respiratory illness emerged in Wuhan, China in January 2020. Politicians, government officials, business leaders, and public-health professionals were unprepared for the most devastating pandemic in a century. Many of the world&’s biggest drug and vaccine makers were slow to react or couldn&’t muster an effective response. It was up to a small group of unlikely and untested scientists and executives to save civilization. A French businessman dismissed by many as a fabulist. A Turkish immigrant with little virus experience. A quirky Midwesterner obsessed with insect cells. A Boston scientist employing questionable techniques. A British scientist despised by his peers. Far from the limelight, each had spent years developing innovative vaccine approaches. Their work was met with skepticism and scorn. By 2020, these individuals had little proof of progress. Yet they and their colleagues wanted to be the ones to stop the virus holding the world hostage. They scrambled to turn their life&’s work into life-saving vaccines in a matter of months, each gunning to make the big breakthrough—and to beat each other for the glory that a vaccine guaranteed. A #1 New York Times bestselling author and award-winning Wall Street Journal investigative journalist lauded for his &“bravura storytelling&” (Gary Shteyngart) and &“first-rate&” reporting (The New York Times), Zuckerman takes us inside the top-secret laboratories, corporate clashes, and high-stakes government negotiations that led to effective shots. Deeply reported and endlessly gripping, this is a dazzling, blow-by-blow chronicle of the most consequential scientific breakthrough of our time. It&’s a story of courage, genius, and heroism. It&’s also a tale of heated rivalries, unbridled ambitions, crippling insecurities, and unexpected drama. A Shot to Save the World is the story of how science saved the world.

The Paper Office for the Digital Age: Forms, Guidelines, and Resources To Make Your Practice Work Ethically, Legally, and Profitably

by Edward L. Zuckerman Keely Kolmes

Significantly revised and updated to include online and computerized aspects of private practice, this essential manual has given many tens of thousands of clinicians the complete record-keeping and risk-reduction tools that every psychotherapy practice needs. The book provides effective methods for obtaining informed consent, planning treatment and documenting progress, managing HIPAA compliance, maintaining clinical and financial records, communicating with clients and third-party payers, and reducing malpractice risk. Drawing from the professional literature, it features key guidance and easy-to-digest pointers about the ethical, legal, and business aspects of practice. With a large-size format for easy photocopying, the book and enclosed CD-ROM include 53 reproducible forms and handouts. Purchasers also get access to a companion website where they can download and customize the reproducible materials. <p><p> New to This Edition: <p>*Updated throughout to reflect today's greater use of electronic/digital technologies in practice management. <p>*Chapter on insurance and billing, coping with managed care, and Medicare. *Chapter on private practice marketing, including Internet and social media dos and don'ts. <p>*Expanded topics: HIPAA compliance, ICD-10, responding to subpoenas, and using online technologies for billing, communication, and record keeping. <p>*Information about hundreds of websites dealing with all aspects of operating a practice. <p><p> See also Clinician's Thesaurus, 8th Edition, by Edward L. Zuckerman, the indispensable resource for conducting interviews and writing psychological reports.

Clinician's Thesaurus: The Guide To Conducting Interviews And Writing Psychological Reports

by Edward L. Zuckerman

Hundreds of thousands of students and early-career professionals have relied on this authoritative report-writing tool, now updated for DSM-5/ICD-10-CM and newer types of evaluations. In a convenient large-size format, the book covers nearly all areas of concern addressed in intakes, evaluations, treatment plans, progress notes, and closing summaries. The user seeking the right wording for a clinical document can skim and select from thousands of technical terms, behavioral descriptors, and standard statements. Also provided are interview questions for almost every symptomatic behavior, a huge collection of mental status questions, a reproducible Mental Status Evaluation summary form, and links to hundreds of internet resources. The companion website offers all the URLs from the book, the reproducible forms, and a handy reference on current psychiatric medications.

Clinician's Thesaurus (Seventh Edition)

by Edward L. Zuckerman

With over 350,000 in print, the Clinician's Thesaurus is an indispensable practitioner resource and course text. It presents thousands of standard words, phrases, clinical tips, and interview questions to help practitioners conduct thorough assessments, accurately describe nearly any clinical situation, and shape clinical observations into effective reports. Finding exactly the right terminology can save hours of paperwork time and improve the quality of documentation. Structured to follow the sequence of a mental health evaluation, the book includes report formats, treatment planning pointers, all DSM-IV-TR and ICD-9-CM diagnostic codes, and much more--all in a large-size format with convenient lay-flat binding. New to This Edition *References, resources, and diagnostic and treatment information are thoroughly updated. *Additional clinical problems: reactive attachment disorder, body dysmorphic disorder, and varieties of violent behaviors. *Sections on strengths assessment and ethical considerations in report writing. *More online resources, including where to obtain free assessment measures and scales. See also The Paper Office for the Digital Age, Fifth Edition, by Edward L. Zuckerman and Keely Kolmes, which provides the essential recordkeeping and risk-reduction tools that every psychotherapy practice needs.

Natural Hormone Balance for Women

by Martin Zucker Uzzi Reiss

A pioneering gynecologist and antiaging specialist with a successful Beverly Hills practice, Dr. Uzzi Reiss shows the way for women who want to turn back the effects of time through natural hormone therapy, but who wonder: is it safe? Does it work? Is hormone therapy right for me? NATURAL HORMONE BALANCE for Women is Dr. Reiss's breakthrough, step-by-step program for women who want to take control of their lives by restoring hormonal balance. This revolutionary, commonsense natural hormone replacement program is designed to meet the individual needs of most women looking to rejuvenate body and mind -- and offers astounding benefits for women of all ages: More energy and stamina * Improved memory * Healthier, more youthful skin * Balanced moods * Less depression and anxiety * Stabilization of weight and more muscle definition * Better sleep patterns * PMS and menopausal symptoms reduced or eliminated * Enhanced sexuality Dr. Reiss takes the confusion out of the medical information you need to know. In clear, nontechnical language, he thoroughly explains: the important difference between standard chemical hormone prescriptions and natural hormone replacements which hormone replacements are best for you and how to adjust them to your maximum individual benefit how to take hormones without worry how to choose the most effective hormonal gel, cream, pill, or sublingual drops, and when to use them. Dr. Reiss has helped thousands of women transform their lives by achieving natural hormone balance. Now you can tap into the replenishing "fountain of youthfulness" that is not only essential for better life, but easier and safer to achieve than ever before.

Reflex Control of the Circulation

by Irving H. Zucker Joseph P. Gilmore

Reflex Control of the Circulation presents an interdisciplinary discussion of concepts in the reflex control of circulation. This volume describes aspects of autonomic receptor physiology, central pathways of reflex control, the electrophysiology of cardiovascular afferents, the interaction between reflexes, the autonomic control of regional blood flows, the autonomic control of fluid and electrolyte balance, and neurohumoral control of the circulation through normal and pathological states (e.g., hypertension, congestive heart failure). In addition, the regulation of regional blood flow during exercise and developmental aspects of reflex control are examined. Any researcher interested in the autonomic system and its role in circulation will find this book fascinating reading.

Ancient Medicine: From Mesopotamia to Rome

by Laura M. Zucconi

This book by Laura Zucconi is an accessible introductory text to the practice and theory of medicine in the ancient world. In contrast to other works that focus heavily on Greece and Rome, Zucconi&’s Ancient Medicine covers a broader geographical and chronological range. The world of medicine in antiquity consisted of a lot more than Hippocrates and Galen.Zucconi applies historical and anthropological methods to examine the medical cultures of not only Mesopotamia, Egypt, Greece, and Rome but also the Levant, the Anatolian Peninsula, and the Iranian Plateau. Devoting special attention to the fundamental relationship between medicine and theology, Zucconi&’s one-volume introduction brings the physicians, patients, procedures, medicines, and ideas of the past to light.

Ancient Medicine: From Mesopotamia to Rome

by Laura M. Zucconi

This book by Laura Zucconi is an accessible introductory text to the practice and theory of medicine in the ancient world. In contrast to other works that focus heavily on Greece and Rome, Zucconi&’s Ancient Medicine covers a broader geographical and chronological range. The world of medicine in antiquity consisted of a lot more than Hippocrates and Galen.Zucconi applies historical and anthropological methods to examine the medical cultures of not only Mesopotamia, Egypt, Greece, and Rome but also the Levant, the Anatolian Peninsula, and the Iranian Plateau. Devoting special attention to the fundamental relationship between medicine and theology, Zucconi&’s one-volume introduction brings the physicians, patients, procedures, medicines, and ideas of the past to light.

Cleaning Up: How Hospital Outsourcing Is Hurting Workers and Endangering Patients (The Culture and Politics of Health Care Work)

by Dan Zuberi

To cut costs and maximize profits, hospitals in the United States and many other countries are outsourcing such tasks as cleaning and food preparation to private contractors. In Cleaning Up, the first book to examine this transformation in the healthcare industry, Dan Zuberi looks at the consequences of outsourcing from two perspectives: its impact on patient safety and its role in increasing socioeconomic inequality. Drawing on years of field research in Vancouver, Canada as well as data from hospitals in the U. S. and Europe, he argues that outsourcing has been disastrous for the cleanliness of hospitals-leading to an increased risk of hospital-acquired infections, a leading cause of severe illness and death-as well as for the effective delivery of other hospital services and the workers themselves. Zuberi's interviews with the low-wage workers who keep hospitals running uncover claims of exposure to near-constant risk of injury and illness. Many report serious concerns about the quality of the work due to understaffing, high turnover, poor training and experience, inadequate cleaning supplies, and on-the-job injuries. Zuberi also presents policy recommendations for improving patient safety by reducing the risk of hospital-acquired infection and ameliorating the work conditions and quality of life of hospital support workers. He makes the case that hospital outsourcing exemplifies the trend towards low-road service-sector jobs that threatens to undermine society's social health, as well as the physical health and well-being of patients in health care settings globally.

Corneal Surgery: Essential Techniques

by Bruno Zuberbuhler David Gartry David Spokes Stephen Tuft

This book is an informative and comprehensive guide to the essential techniques currently employed in corneal surgery. It focuses in particular on two principal areas: the treatment of corneal disorders by means of different forms of corneal transplantation and the use of the Excimer laser to treat refractive disorders. In order to facilitate learning and later deployment of the techniques a multimedia approach is used. Surgical steps are described clearly within the book and can then be observed in detail on the accompanying high-quality DVD. A further feature is the inclusion of a chapter devoted to wet lab training, which presents practical preparatory exercises. This book will be of special value as a handy reference for ophthalmologists who are just embarking upon their surgical training. However, it will also be informative for trained eye surgeons, who will be able to compare their own practice with the presented procedures and to assimilate the latest techniques.

Urticaria and Angioedema

by Torsten Zuberbier Clive Grattan Marcus Maurer

Urticaria is one of the most common diseases encountered in dermatology. The fleeting nature of wheals often makes a first diagnosis by both patients and physicians seem easy. The disease itself is of a highly complex nature, with a variety of clinical manifestations ranging from pinpoint sized wheals to extensive angioedema. Further complexities include the diversity of possible eliciting and aggravating factors, the many different clinical subtypes and the therapeutic responsiveness.This second, extensively revised edition includes the indications listed in the most recent international guidelines, provides a practical, comprehensive review of all clinical aspects and causes, and addresses the diagnosis and therapy of different types of urticaria. Specific chapters are devoted to classification, aetiopathogenesis, patient reported outcomes, acute urticaria, chronic urticaria and its comorbidities, angioedema without weals, inducible urticarias, special populations including children, treatment with antihistamines and omalizumab, other interventions and looking ahead to new therapies. This new edition is a must read for dermatologists, allergists, pediatricians and practitioners of all disciplines who want their patients to benefit from cutting-edge diagnostics and treatments.

Function and Control of the Spx-Family of Proteins Within the Bacterial Stress Response

by Peter Zuber

This SpringerBrief on Spx reviews the investigations that led to the discovery of Spx and its orthologs and ties together the results of various studies that have explored the function and control of spx in Gram-positive organisms. Spx of Bacillus subtilis has been extensively studied, but very little has been published about it. This book incorporates a number of studies that have been conducted in other Gram positive bacteria, which examined the role of Spx orthologs in stress response, bacterial development and virulence. The book contains an overview that will introduce the protein and its orthologous forms, its association with RNA polymerase, the species of Gram-positive bacteria in which it is found, and the conditions in which it is abundant and active. Spx is a member of a large group of proteins belonging to the ArsC/Spx protein family, so the review touches upon the bioinformatic support for the protein family composition and its meaning with regard to protein structure/function.

Klinische Elektroenzephalographie

by Stephan Zschocke Hans-Christian Hansen

Die Autoren beschreiben in dem Band die physiologischen und pathophysiologischen Grundlagen der Elektroenzephalographie (EEG) und machen die Technologie Schritt für Schritt verständlich: Behandelt werden die EEG-Potenziale in ihren verschiedenen Formen sowie der Einsatz der EEG in der Intensivmedizin. Das Werk hilft Ärzten, brauchbare Kurven zu gewinnen, Befunde zu verstehen und zu interpretieren, aber auch Fehler zu vermeiden. Die 3., aktualisierte und überarbeitete Auflage enthält ein neues Kapitel über die EEG in der Neuropädiatrie.

Basiswissen Humangenetik (Springer-lehrbuch)

by Johannes Zschocke Christian Schaaf

Mediziner sind häufig mit Fragen der Humangenetik konfrontiert, ob bei Kindern mit Trisomie 21 oder Mukoviszidose-Patienten. In dem Band werden die Grundlagen der Genetik dargestellt – in Verbindung mit praktischen Fragestellungen: Welche Krankheitsbilder gibt es? Wie werden welche Organe beeinflusst? Darüber hinaus werden spezielle klinische Probleme sowie der Umgang mit Patienten und mit Daten erörtert. Das Lehrbuch ist eine Hilfe für Mediziner, wenn sie Patientengespräche führen, Risiken abwägen und ethische Grundsätze im Blick behalten wollen.

JIMD Reports, Volume 41: Focus Issue: Adults And Metabolism (Jimd Reports #41)

by Johannes Zschocke Eva Morava Verena Peters Matthias Baumgartner Marc Patterson Shamima Rahman

JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.

JIMD Reports - Case and Research Reports, Volume 13

by Johannes Zschocke K. Michael Gibson Garry Brown Eva Morava Verena Peters

JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.

JIMD Reports - Case and Research Reports, 2012/4 (JIMD Reports #9)

by Johannes Zschocke Garry Brown Eva Morava Verena Peters K Michael Gibson

JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.

Biological Microarrays: Methods and Protocols (Methods in Molecular Biology #671)

by Mohammed Zourob Kahp-Yang Suh Ali Khademhosseini

Recent developments in microarray technology have changed the landscape of biology and biomedical research, and they have revolutionized RNA and DNA research. In Biological Microarrays: Methods and Protocols, expert researchers explore exciting new developments in the field, providing a comprehensive approach to biological microarrays that conveys not only the state-of-the-art fundamentals, but also includes applications of the most innovative methods. Chapters address both the application of biological microarrays, including DNA/RNA, apatmer, proteins, tissues, oligonucleotides, carbohydrates, biomaterials, cells, bacteria, and virus microarrays, and also explore the different techniques used for generating microarray platforms. Composed in the highly successful Methods in Molecular BiologyTM series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Wide-ranging and revolutionary, Biological Microarrays: Methods and Protocols serves as a primary source for academics, practitioners, and professionals in related fields, including biologists, biotechnologists, biochemists, analytical chemists, and biomedical, physical, and microsystems engineers, to name a few, appealing to all of those interested in the present and future state of biological microarray research.

Optical Guided-wave Chemical and Biosensors I

by Mohammed Zourob Akhlesh Lakhtakia

For the first time, distinguished scientists from key institutions worldwide provide a comprehensive approach to optical sensing techniques employing the phenomenon of guided wave propagation for chemical and biosensors. This includes both state-of the-art fundamentals and innovative applications of these techniques. The authors present a deep analysis of their particular subjects in a way to address the needs of novice researchers such as graduate students and post-doctoral scholars as well as of established researchers seeking new avenues. Researchers and practitioners who need a solid foundation or reference will find this work invaluable. This first of two volumes contains eight chapters covering planar waveguides for sensing, as well as sensing techniques based on plasmonic waveguides.

A Concise Guide To Intraoperative Monitoring

by George Zouridakis Andrew Papanicolaou

Covering both the applications and the related theory, A Concise Guide to Intraoperative Monitoring provides a general but comprehensive introduction to IOM. Unlike existing texts that typically report the results of specific studies, this book presents comprehensive coverage of the entire procedure, as well as the specific protocols used in hospital practice, examples of typical recordings, possible problems, and recommended solutions. At the end of each chapter the author poses several questions for review. These questions help technologists and medical residents in their preparation for the board exams. Taken together, these features make the book an ideal reference or training manual. <p><p> A Concise Guide to Intraoperative Monitoring begins by discussing the basic principles underlying the generation of bioelectrical signals. It then describes the electronic equipment and the various electrophysiological procedures involved in IOM. From this foundation, the book gradually advances to more specific topics, such as surgical procedures, neuronal structures at risk, the optimum combinations of tests to administer, and the proper interpretation of test results. The material also provides you with a background on general anesthesia and analyzes the effects of various drugs on electrophysiological recordings. A Concise Guide to Intraoperative Monitoring also discusses the proper placement of stimulation and recording electrodes, as well as intervention strategies and equipment troubleshooting.

Life and Learning of Digital Teens: Adolescents and digital technology in the Czech Republic (Young People and Learning Processes in School and Everyday Life #6)

by Jiří Zounek Libor Juhaňák Klára Záleská

This book describes and explains how digital technologies enter adolescents’ everyday life and learning in different contexts and environments. The book is based on research conducted in recent years in the Czech Republic, the results of which are set within a broad theoretical and international framework.The authors consider the theoretical and methodological anchoring of the topic, describing various approaches in an effort to comprehensively describe and understand the learning process of today’s pupils. They focus on ways to explore learning in the digital era, domestication of digital technology in families, and parents' approaches to digital technology. Attention is paid to adolescents’ competences and autonomy in the use of digital technologies, as well as their views on technology in their lives and learning. The authors summarize the most important results of the research, but also consider the options of empirical research and their own experience with the research of such a complex concept.

Medical Arabic

by Abderrahman Zouhir Abdulqadir Abdulkarim

Medical Arabic is a valuable resource for students interested in learning medical Arabic at ACTFL level Advanced Low. Effective communication is essential in health care, and communication is most effective when both parties share a common language, therefore resulting in a comfortable relationship between health care provider and patient. This textbook is intended for those with prior knowledge of Arabic language and grammar. It is designed to provide students with the linguistic and cultural competencies and medical Arabic terminology necessary to communicate in medical settings such as a hospital, clinic, or a community health care facility. Students will be able to ask questions in Arabic and provide answers in common medical situations, conduct patient interviews, and understand a wider variety of possible responses from patients. The book provides clear explanations of medical vocabulary and concepts as they occur in the reading materials to encourage active interaction with the text. The book’s drills are designed as either in-class exercises or homework. The answer key for the book exercises is also provided as a downloadable e-resource. Written by dynamic authors who taught Arabic as a foreign language for several years and reviewed by physicians and professionals in the field, the book is an essential guide for students in medical school, biology, and other science majors. Students will find Medical Arabic more than merely a textbook but rather a pathway to enhance their communication skills effectively.

Pathogenesis and Treatment of Acne and Rosacea

by Christos C. Zouboulis Andreas D. Katsambas Albert M. Kligman

This book, written by experts from across the world, provides comprehensive coverage of acne and rosacea, focusing in particular on pathogenesis and treatment but also considering clinical aspects, prognostic factors, and impacts on quality of life. Both standard knowledge and important, clinically relevant insights that have emerged over the past decade are presented with the goal of assisting the reader in understanding these diseases and improving treatment outcome. It is explained how high-level research has recently given rise to a variety of new concepts in etiology and treatment, and emerging trends are also discussed. The book is in a reader-friendly format that highlights core messages with a very practical and clinical focus. Pathogenesis and Treatment of Acne and Rosacea will be an indispensable reference for all physicians who care for patients with acne or rosacea and for scientists working in the field.

Prions and Diseases

by Wen-Quan Zou Pierluigi Gambetti

Transmissible spongiform encephalopathies (TSE), known as prion diseases, have been recognized for nearly 300 years in animals and almost 100 years in humans. Modern studies, including the protein-misfolding cyclic amplification (PMCA), have greatly advanced our understanding of the pathogenesis of prion diseases and facilitated the identification of new prion diseases in animals and humans. In the second edition of Prions and Diseases, more than 60 leading researchers and clinicians worldwide provide an up-to-date discussion of these unique infectious pathogens and their associated diseases. The book provides up-to-date knowledge about the etiology, pathogenesis, classification, histopathological, and clinical aspects of the full range of animal and human prion diseases. As a result, the book contains by far the most authoritative views about the past, present, and future of prions and prion diseases. The new second edition covers such important emerging topics such as inherited human prion disease, stem-cell models in prion research, human prion disease surveillance, and gene therapy strategies.

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