- Table View
- List View
Anti-Cancer N-Heterocyclic Carbene Complexes of Gold: Thiol “Switch-on” Fluorescent Probes, Thioredoxin Reductase Inhibitors and Endoplasmic Reticulum Targeting Agents (Springer Theses)
by Taotao ZouThis thesis focuses on the development of gold- and non-classical platinum-based anti-cancer agents that display distinctively different anti-cancer mechanisms compared to the commonly used cisplatin. These metal complexes contain N-heterocyclic carbene (NHC) ligands which are able to form strong M-C(NHC) bonds, conferring high stability and favorable lipophilicity, reactivity and binding specificity of metal complexes on biomolecules. The author demonstrates significant advances made in anti-cancer gold(III), gold(I) and platinum(II) complexes. Detailed chemical synthesis, in vitro and/or in vivo anti-cancer activities are clearly presented including: (i) a class of Au(III) complexes containing a highly fluorescent N^N^N ligand and NHC ligand that simultaneously act as fluorescent thiol "switch-on" probes and anti-cancer agents; (ii) a dinuclear gold(I) complex with a mixed diphosphine and bis(NHC) ligand displaying favorable stability and showing significant inhibition of tumor growth in two independent mice models with no observable side effects; and (iii) a panel of stable luminescent cyclometalated platinum(II) complexes exhibiting high specificity to localize to the endoplasmic reticulum (ER) domain, inducing ER stress and cell apoptosis. These works highlight the clinical potential that gold and platinum complexes offer for cancer treatment.
Anti-Capital: The Mesmerising Misnomers
by Jacek TittenbrunThe notion of capital has enjoyed a rich career in the social sciences, its use across a range of subjects and in diverse academic and professional contexts having served to establish its conceptual status as 'given'. With particular attention to human and social capital - including cultural capital - this book traces the roots of this theoretical and conceptual trend to economics, revealing the proliferation of various forms of capital to be based upon an encroachment of the conceptual apparatus of economics into other social sciences. Offering an in-depth, critical analysis of the concepts of human and social capital, as well as their surrounding theories, Anti-Capital: Human, Social and Cultural proposes an alternative theoretical framework, whilst better explaining the realities that they mask in economic terms. A rigorous exploration of the most popular forms of 'capital' in the contemporary social sciences, this book will be of interest to scholars and students of sociology, political and social theory, demography and economics.
Anti-Capitalism
by Ezequiel Adamovsky Marie TrigonaIn Anti-Capitalism, activist and scholar Ezequiel Adamovsky tells the story of the long-standing effort to build a better world, one without an abusive system at its heart. Backed up by arresting, lucid images from the radical artist group United Illustrators, Adamovsky details the struggle against rising corporate power, as that struggle unfolds in the halls of academia, in the pages of radical newspapers, and in the jungles and the streets. From Marx through the Battle of Seattle and beyond, Adamovsky traces the beliefs and politics of the major figures in the anticapitalist tradition and explores modern experiments in building different ways of living, in the process providing an indispensible primer for anyone interested in finding alternatives to the so-called "best system we have"--and anyone interested in joining the fight.
Anti-Capitalism: A Beginner's Guide (Beginner's Guides)
by Simon TormeyThe puncture of the great banking bubble and the dash to austerity has breathed new life into protest movements across the globe and brought anti-capitalist values to the forefront as never before. But what does it mean to be anti-capitalist? And where is anti-capitalism going - if anywhere? Global civil society expert Simon Tormey explores these questions, and more, in this thought-provoking book.Unlike other, ideologically-narrow introductions, Tormey introduces us to all the eclectic groups - anarchists, Marxists, autonomists, environmentalists - and thought that make up the anti-capitalist movement. Providing global and historical context, he takes us from the 1994 Zapatista insurrection through the 1999 Seattle protests right up to Occupy Wall Street, the Indignados of Spain and the current Greek uprisings. Going beyond a mere descriptive take, Tormey weighs up a range of possibilities for bringing about alternatives to the corporate domination of our planet. This is a fascinating and bold exploration of how to understand the world - and how to change it.
Anti-Capitalism: A Beginner's Guide
by Simon TormeySpecifically, the book tackles the questions: Who exactly are the anti-capitalists and what do they want? Simon Tormey examines the ideas of the various components that make up the movement: the anarchists and Marxists, the greens and environmentalists, the anti-corporate activists and utonomists, among many others. He looks in detail at how the movement operates its reliance on a unique combination of word-of-mouth, the internet, and communications technology.
The Anti-Capitalism Reader: Imagining A Geography Of Opposition
by Joel SchalitFrom Seattle and Genoa back to Marx and Gramsci, the left is back, going global to fight the virus of modern greed. A refreshingly non-doctrinaire collection of writings on the theory, practice, and history of anti-capitalist politics from the most well-versed activists and scholars in the movement. Since the demonstrations against the World Trade Organization in Seattle two years ago, the world has witnessed the emergence of a brand new left. Largely focusing on such issues as third-world debt reduction and the emergence of a decidedly undemocratic transnational political order, this new progressivism is a rich and complex phenomenon which demands careful analysis to understand its ascendance ten years after the Cold War—in a time of supposed affluence and ongoing celebration of capitalism’s triumph over the Soviet Union. Aimed squarely at activists and academics, as well those interested in educating themselves about the anti-market tenor of the new left, this is a comprehensive and accessible introduction to anti-capitalist politics and cultures. Contributors include SF Bay Guardian Culture editor and high-tech critic Annalee Newitz, Wall Street author and Left Business Observer editor Doug Henwood, journalist and social critic Liza Featherstone, as well as interviews with influential thinkers such as Slavoj Zizek, Frederic Jameson, Susan George, and Antonio Negri (co-author of Empire). Among the topics explored are the presence of anti-capitalist movements in everyday life, the history of anti-capitalism, strategies of anti-capitalist resistance, regionalism and anti-capitalism, and anti-capitalism and intellectual property. Includes a brief selection of some of the most historically important criticisms of the free market from the likes of Marx, Gramsci, and other Marxist, anarchist, and Situationist thinkers. Editor Joel Schalit is the author of Jerusalem Calling and editor of both Punk Planet magazine and webzine Bad Subjects: Political Education for Everyday Life. He is a regular contributor to the SF Bay Guardian. Contributors: Megan Shaw Rick Prelinger Jason Meyers Annalee Newitz Scott Schaffer Doug Henwood Liza Featherstone Interviews: Slavoj Zizek Frederic Jameson Susan George
The Anti-Capitalist Chronicles
by David HarveyAmidst waves of economic crises, health crises, class struggle and neo-fascist reaction, few possess the clarity and foresight of world-renowned theorist, David Harvey. Since the publication of his bestselling A Brief History of Neoliberalism, Harvey has been tracking the evolution of the capitalist system as well as tides of radical opposition rising against it. In The Anti-Capitalist Chronicles, Harvey introduces new ways of understanding the crisis of global capitalism and the struggles for a better world. While accounting for violence and disaster, Harvey also chronicles hope and possibility. By way of conversations about neoliberalism, capitalism, globalization, the environment, technology, social movements and crises like COVID-19, he outlines, with characteristic brilliance, how socialist alternatives are being imagined under very difficult circumstances. In understanding the economic, political and social dimensions of the crisis, Harvey’s analysis in The Anti-Capitalist Chronicles will be of strategic importance to anyone wanting to both understand and change the world.
Anti-Catholicism and British Identities in Britain, Canada and Australia, 1880s-1920s (Histories of the Sacred and Secular, 1700–2000)
by Geraldine VaughanRecent debates about the definition of national identities in Britain, along with discussions on the secularisation of Western societies, have brought to light the importance of a historical approach to the notion of Britishness and religion. This book explores anti-Catholicism in Britain and its Dominions, and forms part of a notable revival over the last decade in the critical historical analysis of anti-Catholicism. It employs transnational and comparative historical approaches throughout, thanks to the exploration of relevant original sources both in the United Kingdom and in Australia and Canada, several of them untapped by other scholars. It applies a 'four nations' approach to British history, thus avoiding an Anglocentric viewpoint.
Anti-Catholicism in Britain and Ireland, 1600–2000: Practices, Representations and Ideas (Histories of the Sacred and Secular, 1700–2000)
by Claire Gheeraert-Graffeuille Geraldine VaughanThis edited collection brings together varying angles and approaches to tackle the multi-dimensional issue of anti-Catholicism since the Protestant Reformation in Britain and Ireland. It is of course difficult to infer from such geographically and historically diverse studies one single contention, but what the book as a whole suggests is that there can be no teleological narration of anti-Catholicism – its manifestations were episodic, more or less rooted in common worldviews, and its history does not end today.
Anti-Catholicism in Victorian England (Routledge Library Editions: The Victorian World Ser. #36)
by E. NormanFirst published in 1968, this book provides an introduction to the subject of anti-Catholicism in Victorian England and a selection of illustrative documents. It demonstrates that Victorian ‘No Popery’ agitations were in fact almost the last expressions of a long English tradition of anti-Catholic intolerance and, in reality, the legal and socia
The Anti-Christ
by H. L. Mencken Friedrich NietzscheThis is Nietzsche's last book and a fitting capstone to his career. It's succinct, biting, and encapsulates the criticisms of Christianity found in his other works. This edition contains an 8,000-word introduction by its translator, the famous iconoclastic writer H. L. Mencken.
The Anti-Christ
by Friedrich Nietzsche"The Christian concept of a god-the god as the patron of the sick, the god as a spinner of cobwebs, the god as a spirit-is one of the most corrupt concepts that has ever been set up in the world... In him nothingness is deified, and the will to nothingness is made holy." See Sharp Press; Tuscon, AZ -from The Anti-Christ. He's one of the most debated thinkers of the 19th century: Nietzsche and his works have been by turns vilified, lauded, and subjected to numerous contradictory interpretations, and yet he remains a figure of profound import, and his works a necessary component of a well-rounded education. The Anti-Christ, first published in German in 1895, is absolutely vital to any meaningful understanding of Nietzsche the man and Nietzsche the philosopher. An insightful and entertaining indictment of Christianity, it has enraged and inspired generations of readers, and this 1920 translation, by H. L. Mencken, considered the best available, is almost as controversial as the work itself, highlighting the darkest side of Mencken's cynicism. Also available from Cosimo Classics: Nietzsche's The Use and Abuse of History.
The Anti-Christ
by Friedrich NietzscheHere is Friedrich Nietzsche's great masterpiece The Anti-Christ, wherein Nietzsche attacks Christianity as a blight on humanity. This classic is essential reading for anyone wishing to understand Nietzsche and his place within the history of philosophy. "We should not deck out and embellish Christianity: it has waged a war to the death against this higher type of man, it has put all the deepest instincts of this type under its ban, it has developed its concept of evil, of the Evil One himself, out of these instincts-the strong man as the typical reprobate, the 'outcast among men.' Christianity has taken the part of all the weak, the low, the botched; it has made an ideal out of antagonism to all the self-preservative instincts of sound life; it has corrupted even the faculties of those natures that are intellectually most vigorous, by representing the highest intellectual values as sinful, as misleading, as full of temptation. The most lamentable example: the corruption of Pascal, who believed that his intellect had been destroyed by original sin, whereas it was actually destroyed by Christianity!" -Friedrich Nietzsche
The Anti-Christ, Ecce Homo, Twilight of the Idols: And Other Writings
by Friedrich NietzscheNietzsche's late works are brilliant and uncompromising, and stand as monuments to his lucidity, rigor, and style. This volume combines, for the first time in English, five of these works: The Antichrist, Ecce Homo, Twilight of the Idols, Nietzsche contra Wagner, and The Case of Wagner. Nietzsche takes on some of his greatest adversaries in these works: traditional religion, contemporary culture, and above all, his one-time hero, Richard Wagner. His writing is simultaneously critical and creative, revealing his alternative philosophical vision, which, after more than a hundred years, still retains its audacious originality.
Anti-Christian Violence in India (Religion and Conflict)
by Chad M. BaumanDoes religion cause violent conflict, asks Chad M. Bauman, and if so, does it cause conflict more than other social identities? Through an extended history of Christian-Hindu relations, with particular attention to the 2007–2008 riots in Kandhamal, Odisha, Anti-Christian Violence in India examines religious violence and how it pertains to broader aspects of humanity. Is "religious" conflict sui generis, or is it merely one species of intergroup conflict? Why and how might violence become an attractive option for religious actors? What explains the increase in religious violence over the last twenty to thirty years?Integrating theories of anti-Christian violence focused on politics, economics, and proselytization, Anti-Christian Violence in India additionally weaves in recent theory about globalization and, in particular, the forms of resistance against Western secular modernity that globalization periodically helps to provoke. With such theories in mind, Bauman explores the nature of anti-Christian violence in India, contending that resistance to secular modernities is, in fact, an important but often overlooked reason behind Hindu attacks on Christians. Intensifying the widespread Hindu tendency to think of religion in ethnic rather than universal terms, the ideology of Hindutva, or "Hinduness," explicitly rejects both the secular privatization of religion and the separability of religions from the communities that incubate them. And so, with provocative and original analysis, Bauman questions whether anti-Christian violence in contemporary India is really about religion, in the narrowest sense, or rather a manifestation of broader concerns among some Hindus about the Western sociopolitical order with which they associate global Christianity.
Anti-Colonial Resistance in South Africa and Israel/Palestine: Identity, Nationalism, and Race (Routledge Studies in the Modern History of Africa)
by Ran GreensteinThis book provides a comparative historical study of the rise and evolution of anti-colonial movements in South Africa and Israel/Palestine. It focuses on the ways in which major political movements and activists conceptualised their positions vis-a-vis historical processes of colonial settlement and indigenous resistance over the last century. Drawing on a range of primary sources, the author engages with theoretical debates involving key actors operating in their own time and space. Using a comparative framework, the book illustrates common and divergent patterns of political and ideological contestations and focuses on the relevance of debates about race and class, state and power, ethnicity and nationalism. Particular attention is given to South Africa and Israel/Palestine’s links to global campaigns to undermine foreign domination and internal oppression, tensions between the quests for national liberation and equality of rights, the role of dissidents from within the ranks of settler communities, and the various attempts to consolidate indigenous resistance internally while forging alliances with other social and political forces on the outside. This book will be of interest to scholars in the fields of African History, Middle East History, and African Studies, and to social justice and solidarity activists globally.
The Anti-Communist Manifesto
by Jesse KellyA rallying cry striking at the roots of today&’s major issues, Jesse Kelly uses his trademark bombast, intelligence, and humor to take down the most dangerous philosophy in history and address its resurgence in America. The Anti-Communist Manifesto is for anyone who feels alienated by political and popular culture in the United States and recognizes the danger of communism as it threatens to rip apart America&’s social fabric. Discover a fresh look at the daily assault on our freedoms from the insidious communist movement in this country. More than a political statement, this book is an insightful drive through history, philosophy, and current events with one of the most entertaining and fearless conservatives in America at the wheel. From weaponizing race, sex, and gender to hijacking our schools, communism threatens to destroy our cherished American way of life. Featuring practical tools and tactics to not only identify communists but also defend the United States from this malicious enemy, The Anti-Communist Manifesto is an instructive guide for all patriots.
The Anti-Communist Manifestos: Four Books That Shaped the Cold War
by John V. FlemingThe books altered the course of history; the lives behind them have the dark fascination of fiction. The subject of The Anti-Communist Manifestos is four influential books that informed the great political struggle known as the Cold War: Darkness at Noon (1940), by Arthur Koestler, a Hungarian journalist and polymath intellectual; Out of the Night (1941), by Jan Valtin, a German sailor and labor agitator; I Chose Freedom (1946), by Victor Kravchenko, a Soviet engineer; and Witness (1952), by Whittaker Chambers, an American journalist. The authors were ex-Communist Party members whose bitter disillusionment led them to turn on their former allegiance in literary fury.Koestler was a rapist, Valtin a thug. Kravchenko, though not a spy, was forced to live like one in America. Chambers was a prophet without honor in his own land. Three of the four had been underground espionage agents of the Comintern. All contemplated suicide, and two of them achieved it. John V. Fleming's humane and ironic narrative of these grim lives reveals that words were the true driving force behind the Cold War.
An Anti-Communist on the Eastern Front: The Memoirs of a Russian Officer in the Spanish Blue Division 1941-1942
by Vladimir KovalevskiVladimir Kovalevskii’s memoirs record in graphic detail a remarkable military career. As a soldier, a committed anti-communist and Russian patriot he saw from the inside a series of conflicts that ravaged Europe in the first half of the twentieth century. In the First World War he fought the Germans, as a White Russian he opposed the Bolsheviks. He joined the French Foreign Legion and served in Africa before fighting for Franco in the Spanish Civil War and for Hitler in the Spanish Blue Division on the Eastern Front in the Second World War. His memoirs give a vivid insight into the armies he fought with and the causes he fought for – and they show how eventually the mental toll became so great that he was devoured by his own contradictions and the contradictions of his times. His experiences on the Eastern Front during the Second World War were shocking. He hoped the German campaign in the Soviet Union would liberate the Russian people, but after witnessing the grim suffering inflicted on the civilian population by a brutal occupying army he was deeply disillusioned and tormented by a sense of guilt. In the late 1940s, in order to make sense of his life as a soldier and to document the extraordinary sights he’d seen, he wrote these memoirs in Russian. They were buried in an archive for over seventy years, but they have now been edited, annotated and translated for this first English edition.
Anti-Constitutional Populism (Cambridge Studies in Law and Society)
by Martin Krygier Adam Czarnota Wojciech SadurskiAround the world, populist parties have sprung up in formerly and formally liberal-democratic polities, challenging their existing political parties and leaders, and frequently overwhelming them. These challenges and successes were rarely predicted, arriving so soon after the wave of liberal democratic and constitutional enthusiasms, proclamations and institution-building which peaked in the 1990s. Bringing together scholars from law, political science and philosophy, this collection explores the character of contemporary populisms and their relationships to constitutional democracy. With contributors from around the world, it offers a diverse range of nuanced perspectives on populism as a global phenomenon. Using comparative and multi-disciplinary techniques, this book considers the specifics and similarities of populisms, and raises general questions about their nature and potential futures.
Anti-Consumption: Exploring the Opposition to Consumer Culture (Routledge Studies in Critical Marketing)
by Hélène Cherrier Michael S W LeeIn this edited volume, the leading scholars in the field engage with consumers, marketers, corporations and policymakers as well as space dynamics and network formation to provide an in-depth examination of anti-consumption: a voluntary behavioural inclination to minimise rather than grow, to decelerate and simplify and to reduce the unnecessary exploitation of resources fuelled by consumer culture. This book does not place anti-consumption on the high moral ground but rather demonstrates its complexity to spur innovative and critical thinking on how people, organisations, businesses and governments can treat consumption more as a necessity for survival than as a tool for self-expression, pleasure and economic growth. The first part of this book looks at anti-consumption from a diversity of perspectives. It analyses voluntary simplicity, a self-motivated engagement in consumption reduction, and boycotting, a politically-motivated reaction against unacceptable corporate practices, as distinct manifestations of anti-consumption that nonetheless remain rooted in the logic of the market. Paving the way to critical perspectives on the interface between anti-consumption, people and the environment, the second part of the book projects anti-consumption to issues of waste production and provides possible answers to global challenges of resources depletion, social inequalities and global warming. In this section, anti-consumption is critically assessed as an actor of change, both in terms of social change and paradigm change. To move the field forward, the third part of this book presents several theoretical frameworks that help set a roadmap for future research. Anti-Consumption will be of direct interest to scholars and researchers within the fields of marketing, consumer research, business studies, environmental studies and sustainability. It will also be of value to those researching the economics and/or sociology of markets.
The Anti-Corn Law League: 1838-1846
by Norman McCordAlthough the Anti-Corn Law league played a most important part in the politics of the 1840's, there is no modern study of its activities and organization. Based on several years work on the original sources, as well as papers belonging to George Wilson, President of the League for most of its life, this book sheds light on the internal history and organization of the League. Written from a political perspective, Dr McCord describes the origin, organization and activities of the League, together with its effect on the contemporary political scene, and as such, fills an important gap in our knowledge of the political history of early Victorian England. At the same time, the book provides an analysis of an unusually well-documented political pressure group, making it a most welcome addition to literature for historians and economic historians, as well as students of political science. This book was first published in 1958.
Anti-Corrosive Nanomaterials: Design, Characterization, Mechanisms and Applications
by Renhui Zhang Lei Guo Ime Bassey ObotCorrosion is a great challenge in many industries, especially in the automotive, aerospace, and oil and gas industries, with conservative estimations accounting for losses of around 2.2 trillion US dollars per year in the United States alone. Providing a comprehensive overview of the history and development of nanomaterials, this book discusses various practices for protection against corrosion. Key Features: Provides a comprehensive and updated review of major innovations in the field of nanomaterials in industrial, corrosion, and environmental science and engineering Encompasses design, characterization, mechanism, and application of nanomaterials from different strategies on the efficacy and major challenges associated with successful scaleup designing Essential reference for present and future research in nanomaterials Includes relevant aspects of organic and inorganic nanomaterials, hybrid nanomaterials, and nanocoatings in anticorrosion applications Coalescing a wide range of research on nanomaterials and anticorrosion practices, this book is of particular appeal to students, industry professionals, and academics.
Anti-Corruption: Implementing Curriculum Change in Management Education (The Principles for Responsible Management Education Series)
by Wolfgang Amann Ronald Berenbeim Tay Keong Tan Matthias Kleinhempel Alfred Lewis Ruth Nieffer Agata Stachowicz-Stanusch Shiv TripathiSuccessful businesses are built on trust. Employees and colleagues need to trust one another and they need to deserve and receive trust from customers and suppliers. Anti-Corruption provides resources for building trust through the implementation of comprehensive guidelines on how to professionalize ethics and anti-corruption education worldwide in a variety of classroom settings. It is written and tested by highly experienced program directors, deans and professors, in how to adopt, adapt and develop best teaching practice. It highlights successful patterns, details illustrative case studies and offers clear, hands-on recommendations. Anti-Corruption enables business schools, management-related academic institutions, and Executive Training Programs to embed curriculum change quickly to achieve positive outcomes. It enables degree programs and executive education programs to achieve global standards that will be widely followed.
Anti-Corruption and its Discontents: Local, National and International Perspectives on Corruption in Papua New Guinea
by Grant W. WaltonThe fight against corruption is now a core part of development policy and practice. Some call these efforts a ‘war on corruption’. What does this so-called ‘war’ mean for developing countries? And how do international perspectives on corruption relate to local and national concerns? This book examines the relevance of anti-corruption discourse in Papua New Guinea (PNG), one of the most culturally rich and ‘corrupt’ countries on earth. Despite increased international, national and local efforts to address corruption over the past two decades, many fear that levels of corruption continue to rise largely unabated. Some believe that the mismatch between international, national and local assumptions regarding the nature of corruption and how it should be addressed is at the heart of the issue. International anti-corruption initiatives stress ‘zero-tolerance’ and try to strengthen formal state-based institutions. However, many people in PNG are more concerned about maintaining social relationships than following state laws and rules. This book critically examines the implications of the anti-corruption agenda and the collision of international, national and local perspectives. In doing so it provides a diagnostic on international assumptions about corruption and how it should be fought in developing countries, offering surprising and important lessons. This book is essential reading for scholars and students of Development Studies, Geography, Political Studies and Economics, as well as practitioners and policy makers working in development.