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Antimicrobial Photodynamic Therapy: Concepts and Applications
by Siddhardha Busi Ram PrasadAntimicrobial Photodynamic Therapy: Concepts and Applications explores the novel antimicrobial therapeutic technique. As the world searches for new, efficient modalities for fighting microorganisms, this book offers a complete understanding of the concept, and knowledge about the emerging technique ‘antimicrobial photodynamic therapy’ (aPDT) for the scientific communities and budding researchers. The book aligns concepts, significance, and applications of the technique systematically. Chapters in the book cover microorganisms, pathogenesis, conventional treatment methods, and significance of new treatment approaches to the concept of antimicrobial photodynamic therapy. The authors describe the mechanism behind it, with applications and examples from research studies. The book discusses photosensitisers in detail, with one chapter emphasising natural photosensitisers. Use of nanostructures in the antimicrobial photodynamic therapy is elaborated on, and we conclude with a well-explored application of the therapeutic technique in dentistry. Features: Efficiently covers the topic in detail with scientifically proven examples. Applications of the therapeutic approach are well discussed, and readers can learn about the research gaps, challenges, and future of the technique. Starts from basics, enabling readers to understand why the approach is relevant and important for study. Simplistic elucidated concepts and applications make it accessible at all levels.
Antimicrobial Polymers
by Maria Jose Ocio Jose Maria Lagaron Amparo Lopez-RubioThe pioneering guide on the design, processing, and testing of antimicrobial plastic materials and coatingsThe manifestation of harmful microbes in plastic materials used in medical devices and drugs, water purification systems, hospital equipment, textiles, and food packaging pose alarming health threats to consumers by exposing them to many serious infectious diseases. As a result, high demand for intensifying efforts in the R&D of antimicrobial polymers has placed heavy reliance on both academia and industry to find viable solutions for producing safer plastic materials. To assist researchers and students in this endeavor, Antimicrobial Polymers explores coupling contaminant-deterring biocides and plastics--focusing particular attention on natural biocides and the nanofabrication of biocides. Each chapter is devoted to addressing a key technology employed to impart antimicrobial behavior to polymers, including chemical modification of the polymers themselves. A host of relevant topics, such as regulatory matters, human safety, and environmental risks are covered to help lend depth to the book's vital subject matter. In addition, Antimicrobial Polymers:Discusses the design, processing, and testing of antimicrobial plastic materialsCovers interdisciplinary areas of chemistry and microbiologyIncludes applications in food packaging, medical devices, nanotechnology, and coatingsDetails regulations from the U.S. (FDA and EPA) and EU as well as human safety and environmental concernsAchieving cleaner and more effective methods for improving the infection-fighting properties of versatile and necessary plastic materials is a goal that stretches across many scientific fields. Antimicrobial Polymers combines all of this information into one volume, exposing readers to preventive strategies that harbor vast potential for making exposure to polymeric products and surfaces a far less risky undertaking in the future.
Antimicrobial Research and One Health in Africa
by Akebe Luther King Abia Sabiha Yusuf EssackAntimicrobial resistance is recognised among the world’s most challenging problems. Despite its global spread, Africa, specifically sub-Saharan Africa, is the most affected by this malaise. Poor living conditions and inadequate access to sanitation and potable water supplies are among contributing factors that have influenced a high disease burden on the continent, requiring extensive antimicrobials. Weak health systems and the absence of firm policies further aggravate the problem, as the use of antimicrobials is mostly unregulated. The increasing demand for animal protein to meet the starving populations’ demands has also influenced the use of these antimicrobials, including those banned on other continents, for food animal production. The ripple effect of indiscriminate use in humans and animals is the massive discharge of antimicrobials, their residues, antimicrobial-resistant microorganisms and their associated genes into the environment. This 14-chapter unique masterpiece presents the AMR problem in African, addressing the various compartments of the One Health – humans, animals, and the environment, to illustrate the need for concerted efforts in the fight against AMR, especially in Africa. Authors from the four cardinal points present diverse aspects of AMR in Africa, starting with behavioural and social drivers of AMR in Africa. Antimicrobial stewardship in an African context is also discussed. AMR in humans is presented through studies on antibiotic-resistant neonates and nontyphoidal Salmonella infections and the clinical relevance of the genetics of viral resistance. Topics on AMR in mastitis, biosecurity in animal farming and the linkage between disinfectants and AMR are discussed. The environmental dimension of AMR is discussed, notably in the aquatic environment, and its implication for aquaculture and irrigation and using nanomaterials to treat polluted waters from such environments are highlighted. Finally, Africa’s rich floral diversity is portrayed as an eco-friendly and cost-effective approach to combat AMR. Hopefully, the work presented will spur greater collaboration between scientists, environmental, animal and human health practitioners, the general population, and policymakers to assimilate and implement the One Health approach to combating AMR, rather than working in silos on their various sectors
Antimicrobial Resistance: Workshop Report
by Forum on Emerging InfectionsAntibiotic resistance is neither a surprising nor a new phenomenon. It is an increasingly worrisome situation, however, because resistance is growing and accelerating while the world's tools for combating it decrease in power and number. In addition, the cost of the problem--especially of multidrug resistance--in terms of money, mortality, and disability are also rising. This book summarizes a workshop on antimicrobial resistance held by the Forum on Emerging Infections. The goal of the Forum on Emerging Infections is to provide an opportunity for representatives of academia, industry, government, and professional and interest groups to examine and discuss scientific and policy dilemmas of common interest that are specifically related to research on and the prevention, detection, and management of emerging infections. Organized as a topic-by-topic synthesis of presentations and exchanges during the workshop, the book highlights lessons learned, delineates a range of pivotal issues and the problems they raise, and proposes some simplified ideas about possible responses.
Antimicrobial Resistance: Underlying Mechanisms and Therapeutic Approaches
by Vinay Kumar Varsha Shriram Atish Paul Mansee ThakurAntimicrobial resistance (AMR) is a global public health threat that needs immediate attention and action from the scientific community. This book compiles and presents the latest and most important aspects of AMR, including the biology involved, its persistence and spread, and novel approaches to tackle this threat. The book first describes the mechanisms and spread of AMR, and then discusses the various approaches and strategies for combating it. Important topics include, microbial pathogenesis, AMR traits and major mechanisms underlying drug-resistance and the emerging strategies and technologies for combating AMR. Emphasis has been given on current developments about natural products including potent phyto-molecules, antimicrobial peptides and endophytes effective against the drug-resistant microbes and target the main drug-resistance determinants (efflux pumps, biofilms, quorum sensing, plasmids, etc.) in these bacterial pathogens. Other exciting topics include applications of nanomaterials in tackling AMR and CRISPR-Cas based precise sequence-specific antimicrobials. This informative book is meant for students and researchers in basic and medical microbiology and biotechnology. It is also useful to public health professionals and industry experts involved in AMR research and related drug-designing.
Antimicrobial Resistance: Problem Pathogens and Clinical Countermeasures (Infectious Disease And Therapy Ser. #Vol. 48)
by Robert C. Owens Jr. Ebbing LautenbachThis publication provides a state-of-the-art overview of key issues related to antimicrobial resistance, including a focus on key pathogens causing common healthcare-associated and community-acquired infections. The epidemiology and therapeutic considerations of these antimicrobial resistant organisms are discussed, as well as the clinical and heal
Antimicrobial Resistance: Collaborative Measures of Control
by Sunil D. SarojAntimicrobial resistance has existed in nature long before the discovery of antibiotics. The mechanisms of resistance are prevalent among the bacterial population. Over a period of time and facilitated by indiscriminate usage of antibiotics, these mechanisms are transferred from one type of bacteria to another, including the pathogenic ones. In addition, the rate of discovery of novel antimicrobials is much slower than the rate of evolution of antimicrobial resistance. Therefore, there is a need for alternative strategies to control antimicrobial resistance to save lives. In this book, the novel strategies to combat antimicrobial resistance are described, emphasizing collaborative measures of control. We describe the concerted efforts undertaken by global communities to combat antimicrobial resistance in detail. The most efficient strategy could be a behavioral change towards indiscriminate consumption, usage, and prescription of antibiotics.
Antimicrobial Resistance: Omics and Systems Biology Approaches
by Vijay Soni Ajay Suresh AkhadeAntimicrobial resistance (AMR) is increasing globally at an incredible rate, and many infectious diseases have already reached an alarming stage of resistance to existing treatments. WHO reports that nearly1.27 million people currently die each year due to resistant infections, and AMR is projected to account for 10 million annual deaths globally by 2050. There is an urgent need for novel approaches to address this issue. Omics technologies are powerful research tools used extensively to study pathogen biology and the activity of microbial agents. These tools, paired with systems biology approaches, can provide novel insights into antimicrobial susceptibility and resistance, and aid in the development of new, more effective measures to combat resistant pathogens. This book provides a comprehensive overview of omics technologies to study pathogen biology, including proteomics, genomics, transcriptomics, metabolomics, and microbiome analysis, and the role of systems biology in developing strategies to combat resistant pathogens. It addresses environmental reservoirs and mobile genetic agents in AMR, host-pathogen interactions and physiology in the development of resistance, drug repurposing and development, and cutting-edge tools such as machine learning, AI for big data analysis, and genomic surveillance. The final section discusses future perspectives on omics-systems biology in AMR, and identifies opportunities for scientific collaboration in the global fight against antimicrobial resistance. This book serves as a comprehensive and accessible resource for researchers in academia and industry focused on immunology, drug development, biotechnology, and systems biology.
Antimicrobial Resistance: Global Challenges and Future Interventions
by Sabu ThomasAntimicrobial resistance is a major global public health problem. This book focuses on the clinical implications of multi-drug resistant pathogens; tracking AMR and its evolutionary significance; antifungal resistance; and current and alternative treatment strategies for AMR, including antivirulent, antibiofilm and antimicrobial resistance breakers, repurposing of drugs, and probiotic therapy. Advances in antimicrobial stewardship, antibiotic policies from a global perspective and their impacts are also discussed. The book also explores the use of omics approaches to gain insights into antibacterial resistance, and includes chapters on the potential benefits of a ‘One Health approach’ describing the environmental and zoonotic sources of resistant genes and their effects on the global resistance pool.
Antimicrobial Resistance in Agriculture and its Consequences (Current Trends in Antimicrobial Research)
by Arti Gupta Ram PrasadThis book offers comprehensive coverage of all manifestations of resistance in combating infectious diseases and explores advances in antimicrobial resistance in agriculture and their applications in the fight against microbes. It discusses and compares biological, biochemical, and structural aspects of resistance and its evolution. This is a comprehensive tool covering all manifestations of antimicrobial resistance and microbial resistance genes. In addition, it also provides a variety of photographs, diagrams, and tables to help illustrate the material. Novel strategies to combat antimicrobial resistance are also described, emphasizing collaborative measures of control. The underlining molecular mechanisms, which depend not only on the microbe but on the specific drug (target) molecule, are highly diverse and are covered in great detail.Students, researchers, scientists, practitioners, academics, computational biologists, stakeholders, and policymakers can benefit from using Antimicrobial Resistance in Agriculture and its Consequences as a resource that addresses microbial biotechnology, microbiology, ethnopharmacology, toxicology, medicinal plant products, and all disciplines related to antimicrobial research.Features of the book: Covers antimicrobial resistance in agriculture with up-to-date research Includes recent references on each plausible antimicrobial resistance in agriculture Details the possible spread of antibiotic resistance bacteria from animals to humans Provides several perspectives in the resistance flux with modern agricultural practices Describes the public health impact of the use of antibiotics in agriculture Presents cutting-edge research on epigenetics, nanotechnology, and emergent antimicrobial technologies Outlines recent laws and regulatory guidelines in the federal agency, responsibility, and authority
Antimicrobial Resistance in Aquaculture and Aquatic Environments
by Preetham Elumalai Sreeja LakshmiThis book provides the latest information on aquatic AMR from the perspective of inflammation and presents new ideas on the complicated mechanisms of lectin biochemistry and associated interactions. Key features include discussion of mechanisms recently identified to be involving surveillance and monitoring of AMR and AMU, presentation of the latest evidence regarding the molecular approaches in disease therapeutics, and thorough explanation of the concept of one health challenges and current understanding of the significance of its disease resistance related studies. Gene expression studies is another important element of the book, and it is proposed that gene editing technology provides gaining attention in the biological role of fresh water and marine environments. Examples of the many latest molecular approaches, applications and future perspectives in AMR specific topics covered in this book include the information right from the basics to the advancements in this area. The book will be a valuable update and resource for both experienced and younger researchers working in the field of marine biology and immunology.
Antimicrobial Resistance in Bacteria from Livestock and Companion Animals (ASM Books)
by Stefan Schwarz Jianzhong Shen Lina CavacoThe global spread of antimicrobial-resistant pathogenic bacteria is a continuing challenge to the health care of humans and domesticated animals. With no new agents on the horizon, it is imperative to use antimicrobial agents wisely to preserve their future efficacy. Led by Editors Stefan Schwarz, Lina Maria Cavaco, and Jianzhong Shen with Frank Møller Aarestrup, an international team of experts in antimicrobial resistance of livestock and companion animals has created this valuable reference for veterinary students and practitioners as well as researchers and decision makers interested in understanding and preventing antimicrobial resistance.
Antimicrobial Resistance in Developing Countries
by Samuel Kariuki Carlos F. Amábile-Cuevas Po-Ren Hsueh Iruka N. Okeke Denis K. Byarugaba Aníbal De SosaToday, there is considerable literature regarding the subject of antimicrobial resistance. However, most of this information is based on information from developed countries. Very little organized information is available about the subject that critically examines the problem in developing countries. Scattered literature is available in various forms in journals that are often not easily accessible to the affected developing countries. The objective of the book is to put together data and information about the problem of antimicrobial resistance in developing countries addressing the general global perspectives, the risk factors, the current rates, trends, and possibilities for containment as they relate to specific conditions in those developing countries.
Antimicrobial Resistance in the 21st Century (Emerging Infectious Diseases of the 21st Century)
by Karl Drlica David Shlaes I. W. FongThis comprehensive, up-to-date volume defines the issues and offers potential solutions to the challenges of antimicrobial resistance. The chapter authors are leading international experts on antimicrobial resistance among a variety of bacteria, viruses including HIV and herpes, parasites and fungi. The chapters explore the molecular mechanisms of drug resistance, the immunology and epidemiology of resistance strains, clinical implications and implications on research and lack thereof, and prevention and future directions.
Antimicrobial Resistance in the Environment
by Patricia L. Keen Mark H. MontfortsExamines effects of the environmental distribution of antimicrobial resistance genes on human health and the ecosystem Resistance genes are everywhere in nature—in pathogens, commensals, and environmental microorganisms. This contributed work shows how the environment plays a pivotal role in the development of antimicrobial resistance traits in bacteria and the distribution of resistant microbial species, resistant genetic material, and antibiotic compounds. Readers will discover the impact of the distribution in the environment of antimicrobial resistance genes and antibiotics on both the ecosystem and human and animal health. Antimicrobial Resistance in the Environment is divided into four parts: Part I, Sources, including ecological and clinical consequences of antibiotic resistance by environmental microbes Part II, Fate, including strategies to assess and minimize the biological risk of antibiotic resistance in the environment Part III, Antimicrobial Substances and Resistance, including antibiotics in the aquatic environment Part IV, Effects and Risks, including the effect of antimicrobials used for non-human purposes on human health Recognizing the intricate links among overlapping complex systems, this book examines antimicrobial resistance using a comprehensive ecosystem approach. Moreover, the book's multidisciplinary framework applies principles of microbiology, environmental toxicology, and chemistry to assess the human and ecological risks associated with exposure to antibiotics or antibiotic resistance genes that are environmental contaminants. Each chapter has been written by one or more leading researchers in such fields as microbiology, environmental science, ecology, and toxicology. Comprehensive reference lists at the end of all chapters serve as a gateway to the primary research in the field. Presenting and analyzing the latest findings in a field of growing importance to human and environmental health, this text offers readers new insights into the role of the environment in antimicrobial resistance development, the dissemination of antimicrobial resistant genetic elements, and the transport of antibiotic resistance genes and antibiotics.
Antimicrobial Resistance in Wastewater Treatment Processes
by Patricia L. Keen Raphaël FugèreAntimicrobial resistance is arguably the greatest threat to worldwide human health. This book evaluates the roles of human water use, treatment and conservation in the development and spread of antimicrobial resistance. Designed as a companion volume to Antimicrobial Resistance in the Environment (Wiley-Blackwell, 2012), this book is a multi-disciplinary synthesis of topics related to antimicrobial resistance and wastewater treatment processes. Antimicrobial Resistance in Wastewater Treatment Processes assembles detailed discussions written by many of the world's best-known experts in microbiology, civil engineering, chemistry, environmental science, public health and related fields. The book presents a collection of subjects that includes: Current knowledge of the role of the environment in development and spread of antimicrobial resistance Chemical analysis of antibiotics in environmental samples Molecular methods for analysis of antimicrobial resistance genes Advanced wastewater treatment processes and antimicrobial resistance effects Public perception of risk related to health consequences of antimicrobial resistance Public health implications of antimicrobial resistance with focus on wastewater treatment processes Antimicrobial resistance has gained a foothold in the global consciousness as a serious public health threat. There is a much greater appreciation for the role of the environment in the dissemination of antimicrobial resistance and the effects of pollutants that can potentially promote development of resistance in bacteria. Contaminants released from wastewater treatment plants are a concern. In Antimicrobial Resistance in Wastewater Treatment Processes, readers will be guided through examinations of the current science related to this important health issue.
Antimicrobial Resistance of the Human Eye
by S. ShivajiThe book covers antimicrobial resistance in ocular diseases, including the microbiology of the ocular surface, the history and origin of antimicrobials, methods to detect antimicrobial resistance and antimicrobial resistance genes, and the impact of antimicrobial resistance on a variety of ocular diseases. The inclusion of chapters covers bacterial keratitis, fungal keratitis, viral keratitis, acanthamoeba keratitis, endophthalmitis, dry eye disease, post fever retinitis, and uveitis including management and prevention of antimicrobial resistance.Key Features: Focusses on various ocular diseases and their association with antimicrobial resistance; Includes data relevant to drug industry to develop drugs for specific ophthalmic use; Illustrates ocular surface microbiome under various diseased condition;s Highlights the microbes associated with the conjunctiva and cornea of the human eye; Enumerates the changes in the abundance and diversity of the antimicrobial resistant (AMR) microorganisms in the diseased eye. This book is aimed at professionals and researchers in ophthalmology, microbiologists, infectious disease specialists, and public health.
Antimicrobial Stewardship: Principles and Practice
by Kerry L. Laplante Cheston B. Cunha Haley J. Morrill Louis B. Rice Eleftherios MylonakisIn an age where antimicrobial resistance amongst pathogens grows more prevalent, particularly in the hospital setting, antimicrobial stewardship is an evidence-based, proven measure in the battle against resistance and infection. This single comprehensive, definitive reference work is written by an international team of acknowledged experts in the field. The authors explore the effective use of coordinated antimicrobial interventions to change prescribing practice and help slow the emergence of antimicrobial resistance, ensuring that antimicrobials remain an effective treatment for infection. Amongst the first of its kind, this book provides infectious disease physicians, administrators, laboratory, pharmacy, nursing and medical staff with practical guidance in setting up antimicrobial stewardship programs in their institutions with the aim of selecting the optimal antimicrobial drug regimen, dose, duration of therapy, and route of administration.
Antimicrobial Stewardship: Principles and Practice
by Thomas Lodise John McNelis Powel Kazanjian Armen Arshakyan Cesar Arias Allison H. Bartlett Dr Andrew Berti April Bobenchik Hugh Booth Carey-Ann Burnham Michael Calderwood Dr Gerald Capraro Professor Joseph Carreno Kimberle Chapin Dr Christopher W Crank Robert S. Daum Professor Susan Davis George Daikos Dr Tom Dilworth Christopher D Doern Professor Gary V Doern Curtis Donskey Monica Dorobisz Ramy Elshaboury Sandy Estrada Dr Islam Ghazi Dr Jennifer Goldman Dr Blanca Gonzalez Dr Christopher J Graber Inge Gyssens Sajeev Handa Dr Amy Hanson Emily L Heil Elizabeth D Hermsen Styliani Karanika Keith S Kaye Dr Joseph L Kuti Dr Nicole M Mahoney Antonis Markogiannakis Dr Aileen Martinez Dr Dmitriy Martirosov Dr Dayna McManus Renee-Claude Mercier Dr Jacob Morton Dr Jose M Munita Dr Jason Newland Dr David Nicolau Dr Jessica Ortwine Dr Suresh Paudel Dr Jason Pogue Dr Warren Rose John Rotschafer Dr Michael Ruggero Dr Michael Samarkos Nikolaos Sipsas Harold Standiford Dr Melvin Stone Jr Dr Mahlet Tadele Evangelia Theophano Piperaki Dr Philip Toltzis Dr Jeffrey E Topal Damary Torres Leonidas Tzouvelekis Jamie L Wagner Carla Walraven Panayiotis ZiakasIn an age where antimicrobial resistance amongst pathogens grows more prevalent, particularly in the hospital setting, antimicrobial stewardship is an evidence-based, proven measure in the battle against resistance and infection. This single comprehensive, definitive reference work is written by an international team of acknowledged experts in the field. The authors explore the effective use of coordinated antimicrobial interventions to change prescribing practice and help slow the emergence of antimicrobial resistance, ensuring that antimicrobials remain an effective treatment for infection. Amongst the first of its kind, this book provides infectious disease physicians, administrators, laboratory, pharmacy, nursing and medical staff with practical guidance in setting up antimicrobial stewardship programs in their institutions with the aim of selecting the optimal antimicrobial drug regimen, dose, duration of therapy, and route of administration.
Antimicrobial Stewardship for Nursing Practice
by Briette Du Toit Yolanda Van Zyl Maria Clara Padoveze Ligia Maria Abraão Rosely Moralez Figueiredo Jo McEwen Heather Kennedy Nykoma Hamilton Emma Burnett Valerie Ness Fiona Gotterson Prof Elizabeth Manias Rose Gallagher Rita Olans Susie Singleton Joanne BosanquetDrug-resistant infections are one of the greatest threats to human health, and with resistance on the rise, appropriate antimicrobial stewardship (AMS) is more important than ever. This book, written by nurses for nurses, provides a clear and concise approach to good practice in this vital area. Exploring all aspects of AMS, this new book is underpinned by a competency framework endorsed by scientific and professional societies, including the National Institute for Health and Care Excellence (NICE). It explains the practices that ensure optimal use of antibiotics for the best clinical outcome, with both minimal toxicity to the patient and minimal impact on subsequent antimicrobial resistance. This book, the first applied directly to antimicrobial stewardship for nurses, supports standards of proficiency for registered nurses, and can therefore be used by regulators and professional bodies to inform standards of proficiency and guidance. The book covers infection prevention and control, antimicrobial resistance, diagnosis of infection and appropriate antimicrobial use, patient engagement, collaboration between professions and how to implement AMS in nursing practice. Including learning tools such as objectives, practical case studies and questions throughout, as well as lecture slides, this book is an essential read for undergraduate nursing students and specialist nurses worldwide. This book is authored by a multi-national group of experts with representation from professional associations, universities and national public health agencies, such as: - Royal College of Nursing, UK - Cardiff University, UK - University of São Paulo, Brazil - Public Health England, UK - National Centre for Antimicrobial Stewardship, Australia
Antimicrobial Stewardship in Non-Traditional Settings: A Practical Guide
by Shira Doron Maureen CampionThe evolution of Antimicrobial Resistance is outpacing the ability to create novel antibiotics, which is proving to be a global problem in the fact of climate change, population growth, demographic shifts toward aging populations, emerging infections, and other crises. Therefore, clinicians are forced to use the existing antimicrobials more responsibly to preserve their longevity for generations to come. In a parallel vein, there has been a recent regulatory acknowledgement of the importance of prudent antimicrobial prescribing, mandating the implementation of Antimicrobial Stewardship across all healthcare settings. This is harder to manage in a non-traditional setting, which include long-term care facilities, outpatient care clinics, urgent care centers, and others. Given the trends in patient care in these settings—particularly where the aging community is concerned—this is proving to be a growing problem. This is troublesome even for spaces that have university and large hospital affiliations. There is a plethora of data describing the implementation and outcomes of Antimicrobial Stewardship Programs in acute-care hospitals with open-access, evidence-based guidelines endorsed by the Infectious Diseases Society of America. However, non-traditional settings often find themselves struggling to implement the same practices and procedures due to their unique needs and limited resources. There may be variability in access to resources, applicability, and patient-type. This book seeks to inform those in non-traditional healthcare settings on the principles, practice, and outcomes of Antimicrobial Stewardship Programs to improve patient care across all settings. The text begins by unpacking Antimicrobial Stewardship in nontraditional settings then covers specific environments, including long-term care facilities, outpatient clinics, and emergency departments. The text also covers special topics, including veterinary medicine, HIV, oncology, and immunocompromised patients, pediatrics, neonates, transplant, and critical care patients.
Antimicrobial Susceptibility Testing Protocols
by Richard Schwalbe Lynn Steele-Moore Avery C. GoodwinThe clinical microbiology laboratory is often a sentinel for the detection of drug resistant strains of microorganisms. Standardized protocols require continual scrutiny to detect emerging phenotypic resistance patterns. The timely notification of clinicians with susceptibility results can initiate the alteration of antimicrobial chemotherapy and
Antimicrobial Therapies: Methods and Protocols (Methods in Molecular Biology #2296)
by José-Luis Barredo Carlos BarreiroAntimicrobial resistance will become a global health threat since antimicrobial treatments continue at the forefront of the defense against microbial infections. To respond to the issue, this detailed book explores vital methodologies currently in use to advance our understanding of antibiotic issues and answer the worldwide demand for novel antibiotics therapies. Beginning with a review chapter that guides the reader through the worldwide demand for novel antibiotics therapies, the volume continues with sections covering new screening procedures and environmental sources, advances in analytical, microbiological, and biotechnological methodologies, antibiotic production and antibiotic resistances, as well as considerations of drug trials and clinical concerns regarding multi-resistant patients. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Antimicrobial Therapies: Methods and Protocols provides a reference source for health, laboratory, and industrial professionals, as well as for graduate students in a number of bio-sanitary disciplines, including medicine, nursery, biotechnology, veterinary, microbiology, genetics, molecular biology, nutrition, farming, and more.
Antimicrobial Therapy in Veterinary Medicine
by Patricia M. Dowling John F. Prescott Keith E. BaptisteProvides a comprehensive, fully updated reference book to the general principles and clinical applications of antimicrobials in veterinary medicine The sixth edition of Antimicrobial Therapy in Veterinary Medicine has been updated to reflect advances in the field, including new international contributors and a broader global outlook. It includes extensive knowledge of both general principles of mechanisms of antimicrobial drug action including specific classes of antimicrobial agents, as well as chapters dedicated to antimicrobial drug use in a wide range of animal species. As antimicrobial resistance increases as a major global issue in both human and animal health, this book’s renewed focus on antimicrobial stewardship in companion animals, in food animals, and on global aspects keeps it at the forefront of this vital field. The Sixth Edition of this classic text offers: Updates to every chapter, reflecting new developments and research, with a complete examination of the issues associated with antimicrobial resistance A comprehensive reference for all aspects of antimicrobial use in veterinary medicine, encompassing theory and practice A global perspective on antimicrobial therapy, with more international content than previous editions A stronger emphasis on antimicrobial stewardship, with practical guidance for prescribing antimicrobial drugs A companion website with tables and figures from the book available for download Antimicrobial Therapy in Veterinary Medicine is an essential and accessible resource for veterinarians, veterinary students, scientists, and professionals in veterinary medicine and antimicrobial research and stewardship.
Antimicrobial Therapy in Veterinary Medicine
by John F. Prescott Steeve Giguère Patricia M. DowlingThe Fifth Edition of Antimicrobial Therapy in Veterinary Medicine, the most comprehensive reference available on veterinary antimicrobial drug use, has been thoroughly revised and updated to reflect the rapid advancements in the field of antimicrobial therapy. Encompassing all aspects of antimicrobial drug use in animals, the book provides detailed coverage of virtually all types of antimicrobials relevant to animal health. Now with a new chapter on antimicrobial therapy in zoo animals, Antimicrobial Therapy in Veterinary Medicine offers a wealth of invaluable information for appropriately prescribing antimicrobial therapies and shaping public policy.Divided into four sections covering general principles of antimicrobial therapy, classes of antimicrobial agents, special considerations, and antimicrobial drug use in multiple animal species, the text is enhanced by tables, diagrams, and photos. Antimicrobial Therapy in Veterinary Medicine is an essential resource for anyone concerned with the appropriate use of antimicrobial drugs, including veterinary practitioners, students, public health veterinarians, and industry and research scientists.