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Alternative and Complementary Therapies for Cancer: Integrative Approaches and Discovery of Conventional Drugs
by Moulay Alaoui-JamaliCancer is a common disease with a devastating impact on the physical and psychological well being of patients. The diagnosis of cancer brings upon many clinical challenges and questions for which clear and simple answers are not always provided by modern medicine. To date, only limited therapeutic options are available for patients with advanced cancer. The recent shift toward targeted therapies has improved substantially patient's survival, however, relapses are frequent and cure remains rare. This led patients and many health care managers to shift attention to the holistic approach of traditional medicine particularly preparations from herbal products to manage and alleviate the disease. Typically, herbal preparations contain single or multiple plant ingredients, including a number of potential active components. Yet, they remain classified as food supplements and thus are exempt from regulations on quality control and proof of efficacy that govern standard pharmaceuticals. Clinical evidence for many preparations is often based on non-documented or anecdotal evidence. In consequence, several preparations with unproven efficacy are circulating in the market with the fear of interference with standard cancer therapies and/or severe toxicity that some can generate, in addition to the unjustified economical burden to patients. Despite inconsistent and conflicting clinical results single molecules have been isolated from herbal preparations and many are exploited to develop potential novel agents. This has fostered the need to organize a set of timely, in-depth and up-to-date review covering the latest developments in alternative cancer management from a scientific and clinical perspective dedicated to the medical community and health care providers, as well as to patients and their families. This book brings the latest comprehensive cancer information and practical recommendations on the best documented practice of alternative therapies for cancer management put together by recognized experts in the fields of medical oncology, traditional medicine, and cancer pharmacology. It goes hand-in-hand with the patient's medical treatment options, quality of life issues, and more. The book is organized into four major sections: The first is an overview of the cancer syndrome by renowned medical oncologists from the USA and Europe. The second is a comprehensive description of traditional medicine by renowned experts from China and Germany. The third is an overview on the pharmacological impact of herb-based formulations on standard chemotherapy agents used in clinical practice. The fourth is a survey of cases reports from several hospitals with approved practice of alternative medicine. The book will feature simple definitions and essential information grouped in both medical and lay-term terminology, and straightforward illustrations related to human physiology, disease definition, scientific data on know and potential mechanisms of action, and preventive approaches. Finally, the book will feature collaboration of experts from China, India, USA, Canada, Germany, France, and other centres with recognized expertise in alternative/traditional medicine. This international cooperation is crucial to cover the complex topic of alternative therapies for cancer.
Alternative and Unconventional Energy Sources
by Anurodh M. DayalA timely volume for understanding our future energy landscape and for creating a bridge towards a decarbonized energy system Alternative and Unconventional Energy Sources discusses various alternative energy sources and their present usage, including wind, solar, ocean, and geothermal energy, along with unconventional fossil energy sources, such as shale gas. The text covers the development and global adoption of each energy source, along with their environmental and economic impacts, resulting in a comprehensive and in-depth treatment of the subject. This approach provides the reader with a one-stop reference for each particular energy source, making the information accessible to all, regardless of discipline or current level of experience with each energy source. Specific topics covered in Alternative and Unconventional Energy Sources include: The controversial perception of shale gas and its future potential as an energy source Technologies to reduce harmful emissions of CO2 and other waste gases and their potential to cause less global warming Downsides of commonly accepted alternative energy sources, such as the disposal of nuclear waste and land requirements for solar panels How undeveloped countries can make use of local energy sources to become more efficient and competitiveAlternative and Unconventional Energy Sources is a highly accessible and useful resource for geographers, geologists, petroleum engineers, renewable energy specialists, and policy makers who wish to understand the current state of global energy production and where the industry may turn in the coming years.
Alternative pre-mRNA Splicing: Theory and Protocols
by Chris Smith Reinhard Lührmann Stefan StammThis book was written for graduate and medical students, as well as clinicians and postdoctoral researchers. It describes the theory of alternative pre-mRNA splicing in twelve introductory chapters and then introduces protocols and their theoretical background relevant for experimental research. These 43 practical chapters cover: Basic methods, Detection of splicing events, Analysis of alternative pre-mRNA splicing in vitro and in vivo, Manipulation of splicing events, and Bioinformatic analysis of alternative splicing. A theoretical introduction and practical guide for molecular biologists, geneticists,clinicians and every researcher interested in alternative splicing. Website: www.wiley-vch.de/home/splicing
Alternative to Futility
by Elton TruebloodThe author makes a case for revitalizing the church to revitalize the world.
Alternatives For Delivering Public Services: Toward Improved Performance
by Emanuel S. SavasThis book is the result of a program undertaken nine years ago by the Diebold Institute for Public Policy Studies, Inc., to identify and analyze potentials for private sector involvement in the delivery of public services. Since its founding in 1968, the Diebold Institute has focused on this question in the belief that private enterprise is capable of infusing public service delivery with the efficiency in resource allocation and management that is its hallmark, whether through direct involvement as a service provider or as a source of market dynamics and management techniques.
Alternatives For High-level Waste Salt Processing At The Savannah River Site
by National Research CouncilAt the request of the US Department of Energy, the Committee provides a technical review of alternatives selected by representatives of the South Carolina site for processing the high-level radioactive waste salt solutions stored there in 48 below-grade tanks. Annotation c. Book News, Inc. , Portland, OR (booknews. com)
Alternatives To Economic Globalization
by The Editors of the International Forum on Globalizationargues that the current model of economy is both unjust and unsustainable and presents alternatives
Alternatives To Unemployment And Underemployment: The Case Of Colombia
by Michael HopkinsThe creation of jobs is critical in Third World countries where growing populations face unemployment or inadequate employment. Many have put forth theories and suggestions that address this problem, but there has been insufficient empirical analysis of the effects of specific policies on employment growth. The author examines macroeconomic theories of labour market behavior and labour force definitions and concepts, assessing how productive they are in formulating employment strategies for Colombia. The implications of a range of alternative policies for generating jobs, their effectiveness in reducing unemployment, and possible programs for the future are analyzed.
Alternatives Unincorporated: Earth Ethics from the Grassroots (Cross Cultural Theologies Ser.)
by George ZachariahThe victims of environmental destruction are often sidelined in eco-theology and environmental discourse. Movements for ecological justice fail to take into account the voice of those at the grassroots. 'Alternatives Unincorporated' presents an environmental ethics that begins with those on the margins. Using the key example of the Narmada Dam in India and the popular resistance movement which built up against the project, the book examines the collective action of subaltern communities in caring for their local environment. The book frames these movements as theological texts that inform a life-affirming earth ethics. The aim of the book is to challenge prevailing social and ecological dynamics and to affirm the interconnectedness of social justice and environmental action.
Alternatives for Dermal Toxicity Testing
by Howard I. Maibach Chantra Eskes Erwin Van VlietThis book provides comprehensive information on the alternative (non-animal) dermal toxicity test methods currently available for industrial, regulatory, and academic use and also explores potential future developments. It encompasses all areas of dermal toxicity, including skin irritation, skin corrosion, skin sensitization, UV-induced effects, and skin genotoxicity. An individual chapter is devoted to each test method, with coverage of the scientific basis, validation status and regulatory acceptance, applications and limitations, available protocols, and potential role within testing strategies. In addition, perspectives from the test developer are presented, for example regarding critical steps in the protocol. The closing section addresses areas that may be of relevance for the future of dermal toxicity safety testing, including the validation and regulatory acceptance of integrated testing strategies, novel complex skin models, and high-throughput screening techniques.
Alternatives for Environmental Valuation (Routledge Explorations in Environmental Economics #Vol. 4)
by Michael Getzner Clive Spash Sigrid StaglMethods for raising awareness of how human’s value the environment range from monetary valuation through to greater public participation in decisions. In this book a group of international experts explore innovative alternatives which are critically evaluated and compared. Lessons are drawn from both the successes and failures of different approaches. Case studies address a wide variety of cutting edge environmental problems from agro-forestry and wetlands to climate change, biodiversity and genetically modified organisms.
Alternatives for Managing the Nation's Complex Contaminated Groundwater Sites
by Robert J. KattAcross the United States, thousands of hazardous waste sites are contaminated with chemicals that prevent the underlying groundwater from meeting drinking water standards. <P><P>These include Superfund sites and other facilities that handle and dispose of hazardous waste, active and inactive dry cleaners, and leaking underground storage tanks; many are at federal facilities such as military installations. While many sites have been closed over the past 30 years through cleanup programs run by the U.S. Department of Defense, the U.S. EPA, and other state and federal agencies, the remaining caseload is much more difficult to address because the nature of the contamination and subsurface conditions make it difficult to achieve drinking water standards in the affected groundwater.
Alternatives for the Demilitarization of Conventional Munitions
by Engineering Medicine National Academies of SciencesThe U.S. military has a stockpile of approximately 400,000 tons of excess, obsolete, or unserviceable munitions. About 60,000 tons are added to the stockpile each year. Munitions include projectiles, bombs, rockets, landmines, and missiles. Open burning/open detonation (OB/OD) of these munitions has been a common disposal practice for decades, although it has decreased significantly since 2011. OB/OD is relatively quick, procedurally straightforward, and inexpensive. However, the downside of OB and OD is that they release contaminants from the operation directly into the environment. Over time, a number of technology alternatives to OB/OD have become available and more are in research and development. Alternative technologies generally involve some type of contained destruction of the energetic materials, including contained burning or contained detonation as well as contained methods that forego combustion or detonation. Alternatives for the Demilitarization of Conventional Munitions reviews the current conventional munitions demilitarization stockpile and analyzes existing and emerging disposal, treatment, and reuse technologies. This report identifies and evaluates any barriers to full-scale deployment of alternatives to OB/OD or non-closed loop incineration/combustion, and provides recommendations to overcome such barriers.
Alternatives in Cancer Therapy
by Ross Pelton Lee OverholserTHE COMPLETE GUIDE TO NON-TRADITIONAL TREATMENTS
Alternatives in Development: Local Politics and NGOs in China and India
by Abhijit Dasgupta LiyiyuThis book deals with the dynamics of local-level politics in China and India. China introduced new policies to restructure local politics in 1978. In place of communes, civil society organizations and cooperatives were introduced in villages. More changes came about with the introduction of the Organic Law of the Villagers' Committees of the People's Republic of China in 1998. The new local power structure includes state-sponsored institutions like Villagers Committees and the traditional civil society organizations (CSOs) and non-government organizations (NGOs). As in China, local politics in India undergoes considerable changes during the last few decades. Panchayati Raj Institutions (PRIs) were reformed in 1992 with a constitutional amendment act. CSOs and NGOs were allowed to function. Against this background, the present book is undertaken with the objectives first, to present two different models of local politics and second, to compare the two, finally to focus on the two different models of development. This book will interest scholars of rural governance, rural transformation, and the role of the grassroots CSOs and NGOs in shaping development program and growth in the two large countries in Asia.
Alternatives in Grammar and Cognition (Palgrave Studies in Pragmatics, Language and Cognition)
by Nicole Gotzner Richard Breheny Jesse A. Harris Yael SharvitThis edited book brings together research investigating foundational issues relating to the generation and restriction of alternative sets from theoretical and empirical perspectives. It includes contributions from noted scholars in the field to provide theoretical arguments, opinionated perspectives synthesizing existing positions, and empirical evidence from experimentation and fieldwork in support of a theoretical framework. Alternatives have come to occupy a central place in formal semantic theory, and are referenced in notable accounts of various phenomena, including focus, negation, implicature, modality, counterfactuals, and contrastive topics, among others. More recently, experimental investigations have addressed the mental activation and availability of alternatives in sentence comprehension and memory representations, finding that alternative meanings are computed during incremental processing, and persist in memory after sentence completion for a limited amount of time. The diverse perspectives represented in this volume will serve to clarify and guide the major avenues available in future research on the topic, and the book will be of interest to graduate students and researchers in fields such as linguistics (especially psycholinguistics and experimental pragmatics), philosophy and cognitive science.
Alternatives in Mobilization: Ethnicity, Religion, and Political Conflict
by Jóhanna Kristín Birnir Nil Seda ŞatanaWhat determines which identity cleavage, ethnicity or religion, is mobilized in political contestation, be it peaceful or violent? In contrast to common predictions that the greatest contention occurs where identities are fully segmented, most identity conflicts in the world are between ethnic groups that share religion. Alternatives in Mobilization builds on the literature about political demography to address this seeming contradiction. The book proposes that variation in relative group size and intersection of cleavages help explain conundrums in the mobilization of identity, across transgressive and contained political settings. This theory is tested cross-nationally on identity mobilization in civil war and across violent conflict in Pakistan, Uganda, Nepal and Turkey, and peaceful electoral politics in Indonesia. This book helps illustrate a more accurate and improved picture of the ethnic and religious tapestry of the world and addresses an increasing need for a better understanding of how religion contributes to conflict.
Alternatives in Regulated River Management
by James A. GoreResearchers and managers of regulated river systems will find this volume useful in acquiring information for deciding an integrated management plan for regulated river operations. Rather than the ecological theory of impacts of flow regulation, emphasis has been placed on methods to predict water quality and habitat alterations, as well as techniques to mitigate impacts from various operational scenarios. Although most chapters refer to impacts of riverine impoundments, these alternatives apply to any regulated situation in which changes in water quality or flow pattern occur. The predictive modeling techniques are explained primarily from a theoretical background. However, extensive bibliographies can guide the uninitiated to specific texts and software. Where controversial techniques have been presented, alternate methods are also described. Major topic areas include water quality problems, channel modification and management, ecological modeling and management, as well as a section on perspectives for ecological management and special problems in developing nations.
Alternatives to Animal Testing: Proceedings of Asian Congress 2016
by Hajime Kojima Troy Seidle Horst SpielmannThis open access book presents recent advances in the pure sciences that are of significance in the quest for alternatives to the use of animals in research and describes a variety of practical applications of the three key guiding principles for the more ethical use of animals in experiments – replacement, reduction, and refinement, collectively known as the 3Rs. Important examples from across the world of implementation of the 3Rs in the testing of cosmetics, chemicals, pesticides, and biologics, including vaccines, are described, with additional information on relevant regulations. The coverage also encompasses emerging approaches to alternative tests and the 3Rs. The book is based on the most informative contributions delivered at the Asian Congress 2016 on Alternatives and Animal Use in the Life Sciences. It will be of value for those working in R&D, for graduate students, and for educators in various fields, including the pharmaceutical and cosmetic sciences, pharmacology, toxicology, and animal welfare. The free, open access distribution of Alternatives to Animal Testing is enabled by the Creative Commons Attribution license in International version 4: CC BY 4.0.
Alternatives to Antibiotics against Pathogens in Poultry
by Awad A. Shehata Guillermo Tellez-Isaias Wolfgang EisenreichThis volume provides a comprehensive overview of poultry intestinal health and recent advances in alternatives to drug treatment of significant disorders. The chapters start with an insight into immunological processes and the communities of gut microbiota. In the following, a range of antibiotic alternatives in poultry feed and production management is presented, including enzymes, phytobiotics, bacteriophages, the use of probiotics, synbiotics, and many more. Expert contributions on the latest technological and diagnostic developments in the field round off this work to accelerate the study of natural products and next-generation disease therapy. Meeting the demand to combat increased resistance to classic treatment methods, this book forms an indispensable guide for all professionals, veterinarians, nutritionists, students and researchers in the poultry industry, food production, and academia.
Alternatives to Antibiotics: Recent Trends and Future Prospects
by Tilak Saha Manab Deb Adhikari Bipransh Kumar TiwaryThis book discusses prospective alternative approaches to fight bacterial infections to minimize the indiscriminate use of conventional antibiotics. It offers the current knowledge on research and development of alternative antibacterial agents such as probiotics, nanobiotics etc. while it also discusses newly emerging trends such as phage therapy, antibody therapy etc. The book highlights on the phytochemicals with potent antibacterial activities as alternatives to conventional antibiotics. Chemical modification to develop next generation antibiotics with enhanced efficacy has also been included. Such modifications are reported to overcome the inherent resistance of the parent antibiotics. Phage therapy and targeted antibodies are considered as potential alternative approaches to treat bacterial ailments and represent areas of cutting-edge research and have therefore been discussed with sufficient care. Mainly, the book highlights various approaches other than conventional antibiotics in treating bacterial infections. The scientific advancements in these areas will strengthen the ‘One Health’ approach benefiting human beings, animals and environment as well. This book is a comprehensive resource to cater researchers, biological scientists, herbalists and clinical practitioners with up-to-date information on antibacterials other than antibiotics.
Alternatives to Blood Transfusion in Transfusion Medicine
by Jean-François Hardy Phillipe van der Linden Alice ManiatisMeeting the needs of patients while minimizing blood transfusions requires special expertise, precise monitoring and innovative techniques. This cutting-edge resource covers all the important clinical aspects of transfusion medicine in diverse clinical settings, with a special emphasis on alternatives to transfusion.Edited by a multidisciplinary team consisting of a transfusion specialist, an anesthesiologist and an intensive care specialist this book is endorsed by the Network for Advancement of Transfusion Alternatives. The contributors review the appropriate use of fluids and of blood products, and describe the latest treatment options available to decrease the need for allogeneic blood products including:Argon beamCell saverHarmonic scalpelNormovolemic haemodilutionSynthetic erythropoietinAntifibrinolyticsRecombinant factor VIIaAdvanced monitoring of hemostasisIntravenous ironThe new edition is a key reference source for all those involved in the practice of blood management and conservation.
Alternatives to Capitalism: Proposals for a Democratic Economy
by Erik Olin Wright Robin HahnelWhat would a viable free and democratic society look like? Poverty, exploitation, instability, hierarchy, subordination, environmental exhaustion, radical inequalities of wealth and power--it is not difficult to list capitalism's myriad injustices. But is there a preferable and workable alternative? Alternatives to Capitalism: Proposals for a Democratic Economy presents a debate between two such possibilities: Robin Hahnel's "participatory economics" and Erik Olin Wright's "real utopian" socialism. It is a detailed and rewarding discussion that illuminates a range of issues and dilemmas of crucial importance to any serious effort to build a better world.From the Trade Paperback edition.
Alternatives to Cognition: A New Look at Explaining Human Social Behavior
by Christina LeeIn this provocative book, Christina Lee takes a consciously critical approach to the apparently unchallenged principle that conscious thought is the cause of all human behavior. Without becoming polemical or destructive, she reconsiders a wide range of issues in mainstream American and European social psychology. Suitable for an international audience, the book deals with issues in mainstream American and European social psychology. It assumes some familiarity with contemporary social and applied psychology, and would be appropriate as a text or supplementary reading for senior undergraduate and postgraduate courses in social psychology and psychological theory, although it is also written with an academic research audience in mind. While it is written largely for psychologists, it would also be of interest to academics from other social-science disciplines with a general interest in explanations of individual social behavior.
Alternatives to Domestic Violence: A Homework Manual for Battering Intervention Groups
by Kevin A. Fall Shareen HowardAlternatives to Domestic Violence, 4th Edition is an interactive treatment workbook designed for use with a wide variety of accepted curricula for domestic violence intervention programs. This new edition adds and revises the exercises and stories in every chapter, covering important topics such as respect and accountability, maintaining positive relationships, good communication, parenting, substance abuse, digital abuse, and sexuality. Chapters on parenting, substance abuse, and religion have also been heavily revised based on current literature and group member feedback. The chapters provide a comprehensive collection of vital topics, including topics rarely addressed in other curricula, and exercises help the group members learn new strategies for leading a life of cooperation and shared power. Continuing the tradition of past editions, this edition not only focuses on the content of a good BIPP curriculum, but it also stresses the group process elements that form the backbone of any quality approach.