- Table View
- List View
Bacteriophages: Biology, Technology, Therapy
by David R. Harper Stephen T. Abedon Benjamin H. Burrowes Malcolm L. McConvilleThis first major reference work dedicated to the mannifold industrial and medical applications of bacteriophages provides both theoretical and practical insights into the emerging field of bacteriophage biotechnology. The book introduces to bacteriophage biology, ecology and history and reviews the latest technologies and tools in bacteriophage detection, strain optimization and nanotechnology. Usage of bacteriophages in food safety, agriculture, and different therapeutic areas is discussed in detail. This book serves as essential guide for researchers in applied microbiology, biotechnology and medicine coming from both academia and industry.
Bacteriophages: Biology and Applications
by Elizabeth Kutter Alexander SulakvelidzeIn response to the emergence of pathogenic bacteria that cannot be treated with current antibiotics, many researchers are revisiting the use of bacteriophages, or phages, to fight multidrug-resistant bacteria. Bacteriophages: Biology and Applications provides unparalleled, comprehensive information on bacteriophages and their applications, such as
Bacteriophages: Methods and Protocols, Volume 3 (Methods in Molecular Biology #1681)
by Martha R.J. Clokie Andrew M. Kropinski Rob LavigneRanging from the evolution of pathogenicity to oceanic carbon cycling, the many and varied roles that bacteriophages play in microbial ecology and evolution have inspired increased interest within the scientific community. Bacteriophages: Methods and Protocols pulls together the vast body of knowledge and expertise from top international bacteriophage researchers to provide both classical and state-of-the-art molecular techniques. With its well-organized modular design, Volume 2: Molecular and Applied Aspects examines a multitude of topics, including the bacteriophage genomics, metagenomics, transcriptomics, and proteomics, along with applied bacteriophage biology. Written in the highly successful Methods in Molecular Biology(tm) series format, chapters consist of brief introductions to the subject, lists of the necessary materials and reagents, readily reproducible laboratory protocols, and a Notes section which details tips on troubleshooting and avoiding known pitfalls. Thorough and cutting-edge, Bacteriophages: Methods and Protocols is a valuable reference for experienced bacteriophage researchers as well as an easily accessible introduction for newcomers to the subject.
Bacteriophages: Practical Applications for Nature's Biocontrol
by Sabah A.A. Jassim Richard G. LimogesBacteriophages: Practical Applications for Nature's Biocontrol' presents the latest information on uses in healthcare settings as well as animal husbandry, management and care of farm animals by using enhanced phages to replace antibiotics for growth promotion in animal feed or to prevent, control and treat disease in animals. The book will provide an overview of the function of phages and what researchers need to know, from phage hunting to laboratory design, management, production and application using different tools and methods. These key aspects will be discussed through a series of dedicated chapters, with topics covering auditing, validation, data analysis, microbial identification, culture media, and contamination control, etc.
Bacteriophages: Methods and Protocols (Methods in Molecular Biology #2738)
by Ebenezer TumbanThis volume provides detailed protocols for the isolation, enumeration, characterization of diverse bacteriophages, including both small to jumbo bacteriophages, from soil, fecal, municipal wastewater, and from food niche samples. Chapters highlight the diversity of bacteriophages in different environments, quantifications using culture, molecular techniques, protocols for isolate, interaction of bacteriophage proteins with host cells, and how to use bacteriophages to transfer foreign genetic elements to bacterial strains. In addition to the above, chapters feature the application of bacteriophages/bacteriophage-derived products. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips (in the Notes section) on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Bacteriophages: Methods and Protocols aims to ensure successful results in further study of this vital field.
Bacteriophages as Drivers of Evolution: An Evolutionary Ecological Perspective
by Stephen T. AbedonThis monograph emphasizes the many facets of bacterial evolution as impacted by bacterial interactions with phages, as well as, to a lesser degree, the evolutionary impact of phages on other organisms, including other phages. The book starts with a general overview of bacteriophages. Topics discussed in detail include but are not limited to mutagenesis, migration, natural selection and genetic drift as the drivers of evolution as well as an extensive discussion from the author’s unique perspective on phage ecology.
Bacteriophages in Health and Disease
by Paul Hyman Andrew Kropinski Sarah Kuhl Andre Letarov Stephen T AbedonBacteriophages are viruses that infect bacteria. As such, they have many potential uses for promoting health and combating disease. This book covers the many facets of phage-bacterial-human interaction in three sections: the role and impact of phages on natural bacterial communities, the potential to develop phage-based therapeutics and other aspects in which phages can be used to combat disease, including bacterial detection, bacterial epidemiology, the tracing of fecal contamination of water and decontamination of foods.
Bacteriophages, Volume 1: Methods and Protocols, Volume 1: Isolation, Characterization, and Interactions (Methods in Molecular Biology #501)
by Andrew Kropinski Martha R. ClokieRanging from the evolution of pathogenicity to oceanic carbon cycling, the many and varied roles that bacteriophages play in microbial ecology and evolution have inspired increased interest within the scientific community. Bacteriophages: Methods and Protocols pulls together the vast body of knowledge and expertise from top international bacteriophage researchers to provide both classical and state-of-the-art molecular techniques. With its well-organized modular design, Volume 1: Isolation, Characterization, and Interactions examines a multitude of topics, including the isolation of phages, morphological and molecular characterization, and interaction with bacteria. Written in the highly successful Methods in Molecular BiologyTM series format, chapters consist of brief introductions to the subject, lists of the necessary materials and reagents, readily reproducible laboratory protocols, and a Notes section which details tips on troubleshooting and avoiding known pitfalls.<P><P> Thorough and cutting-edge, Bacteriophages: Methods and Protocols is a valuable reference for experienced bacteriophage researchers as well as an easily accessible introduction for newcomers to the subject.
Bacteriophages, Volume 2: Methods and Protocols, Volume 2: Molecular and Applied Aspects (Methods in Molecular Biology #502)
by Andrew Kropinski Martha R. ClokieRanging from the evolution of pathogenicity to oceanic carbon cycling, the many and varied roles that bacteriophages play in microbial ecology and evolution have inspired increased interest within the scientific community. Bacteriophages: Methods and Protocols pulls together the vast body of knowledge and expertise from top international bacteriophage researchers to provide both classical and state-of-the-art molecular techniques. With its well-organized modular design, Volume 2: Molecular and Applied Aspects examines a multitude of topics, including the bacteriophage genomics, metagenomics, transcriptomics, and proteomics, along with applied bacteriophage biology. Written in the highly successful Methods in Molecular Biology™ series format, chapters consist of brief introductions to the subject, lists of the necessary materials and reagents, readily reproducible laboratory protocols, and a Notes section which details tips on troubleshooting and avoiding known pitfalls.<P><P> Thorough and cutting-edge, Bacteriophages: Methods and Protocols is a valuable reference for experienced bacteriophage researchers as well as an easily accessible introduction for newcomers to the subject.
Baculovirus: Methods and Protocols (Methods in Molecular Biology #2829)
by Manon M. J. CoxThis detailed volume provides up-to-date guidance on techniques used to work with baculoviruses and insect cells. The book provides basic methods to create recombinant baculoviruses, to improve productivity, to produce a variety of products, to purify products, to quantify baculovirus stocks or to quantify product produced, and it concludes with alternative uses of either baculovirus or insect cells as tools. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and comprehensive, Baculovirus: Methods and Protocols serves as an ideal guide for researchers looking to overcome some of the limitations associated with the early baculoviral vectors and cell lines.
Baculovirus and Insect Cell Expression Protocols (Methods in Molecular Biology #1350)
by David W. MurhammerBaculovirus Expression Protocols, Second Edition, provides the detailed steps required to perform the techniques involved with the use of baculoviruses and insect cell culture and discusses problems that may be encountered. This newly-revised and updated edition provides a cutting edge step-by-step guide for biochemists, molecular biologists, biochemical engineers and others using the BEVS and/or insect cells for producing recombinant proteins. Furthermore, Baculovirus Expression Protocols, Second Edition, provides assistance to scientists and engineers interested in developing and producing baculovirus insecticides. Authors list all available insect cell lines and provide methods for isolating new cell lines. The procedures involved in producing products, both at laboratory scale and large scale, are discussed, as well as the production in insect larvae. It is hoped that this volume will not only aid the user in successfully completing the tasks described herein, but will also stimulate the development of improved techniques and new applications of baculoviruses and insect cell culture. Timely and thorough, this volume will become an essential reference for anyone using baculoviruses and insect cell culture.
Baculovirus Expression Protocols (Methods in Molecular Biology #39)
by Christopher D. RichardsonBaculovirus Expression Protocols offers both industrial and university-based researchers a comprehensive comilation of the latest baculovirus techniques along with step-by-step instructions and time-saving techniques. The contributors-leading authorities in the field-present the assorted expression plasmids currently in use, guide the reader through the process of generating and selecting recombinant virus, and describe specific examples of recombinant protein production and purification. The emphasis is on alternative and simpler screening techniques for the selection of recombinant baculovirus. The book also surveys the various insect cell lines currently compatible with the baculovirus system. Highlights include production of recombinant virus using linearized DNA and vectors that contain a b-galactosidase indicator and a complete list of expression vectors currently available. Detailed descriptions for the scale-up of protein production using spinner flasks, bioreactors, and insect larvae are also included. Baculovirus Expression Protocols offers both industrial and university-based researchers an outstanding collection of reproducible, step-by-step laboratory protocols. It will immediately become indispensable for anyone working with baculoviruses and their application in the expression of recombinant proteins in insect cells.
Bad: The Autobiography of James Carr
by James CarrAn unapologetic, brutal memoir from notorious 60s career criminal and Black Panther James Carr. BAD covers Carr's life from his first arrest for burning down his school at age 10, through merciless stints in San Quentin, where he shared a cell with famed Soledad Brother George Jackson, through his tragic post-incarceration murder in San Jose in 1972. A savage indictment of the American penal system, this classic release has new significance as part of a growing, urgent demand for prison reform.
Bad: A Novel (Mad, Bad, and Dangerous to Know Trilogy #2)
by Chloé Esposito"Alvina is a character that readers won't soon forget--funny, fierce, and fabulous."--Booklist (starred review)Stealing her sister's life was only the beginning. Alvie Knightly flees Sicily for a suite at the Ritz after her not-so-playful sibling rivalry ends in murder. Beautiful, spoiled Beth may be out of the way, but Alvie's discovering what happens when you steal your twin's identity. Especially now Beth's body has been found. The police aren't the only ones Alvie has to worry about. Her hot new boyfriend has vanished, along with every penny of their stolen riches. But Alvie has never shied away from a challenge. She pursues the traitor to Rome in a life-or-death game of cat and mouse. Hell hath no fury like a woman scorned - but can Alvie get revenge before her own crimes catch up with her?
Bad
by Jean FerrisIn an attempt to please her friends, sixteen-year-old Dallas goes along with their plan to rob a convenience store and when her father refuses to allow her to come home, she is sentenced to six months in the Girls' Rehabilitation Center.
Bad: An Unprecedented Investigation into the Michael Jackson Cover-Up (Front Page Detectives)
by Dylan HowardAn Inside View into the Dark Side of a Music Icon He was the King of Pop, a superstar without equal, the idol of millions of young people around the world. But was Michael Jackson also a sexual predator without equal, someone who preyed on the very fans who adored him? Bad is the revelatory untold true story of the strange and larger-than-life career of Michael Jackson, the King of Pop. In the wake of the controversial two-part documentary Leaving Neverland, which told the stories of two young boys who were befriended by the singer and have claimed they suffered years of agonizing abuse, Dylan Howard set out to investigate Jackson&’s life and death in unprecedented depth, to determine—as one lawyer suggested—that the pop star ran &“the most sophisticated child sexual abuse procurement and facilitation operation the world has known.&” After all the highly publicized trials and unfounded accusations, stunning new information has finally come to light: irrefutable evidence that one of the best-known, best-loved figures in the world was a monster behind closed doors—a foul-mouthed, abusive, drug-sodden freak whose deeds and the reasons for those deeds are revealed now for the first time. A dramatic narrative account based on dozens of interviews, Howard shares Jackson&’s own riveting personal journal—obtained exclusively for this book—interviews with family members, multiple first-person sources—some of whom have asked to remain anonymous—as well as thousands of pages of court documents. What he uncovers is a man who was both naive and Machiavellian, unorthodox, a devoted father, shrewd businessman, and drug addict whose life was cut short but whose sound and style have influenced artists of various genres and generations. Remarkably though, in death, there remains two portraits of Michael Jackson: the reigning King of Pop, and a pedophile whose pattern of abuse ruined his reputation. Fans and individuals alike will forever be asking if the insidious claims being made about MJ are true. This is the new narrative and the sad legacy of one of the best-selling music artists of all time. Here is his life story, told for the first time with stories and testimony that will leave you shaken.
Bad (Fearless # #13)
by Francine PascalI FINALLY HAVE SAM. I FINALLY HAVE A FAMILY. I FINALLY HAVE A WAY OUT. WHAT'S SO BAD ABOUT THAT? <P> Gaia Moore is genetically incapable of feeling fear. In this story, Gaia finally has Sam and he's everything she ever desired. But something - or someone - stands in the way of her true happiness. Loki has his sights set on her and he won't let anyone stop him from getting what he wants.
Bad: Fearless (Fearless Ser. #No. 13)
by Francine PascalI FINALLY HAVE SAM. I FINALLY HAVE A FAMILY. I FINALLY HAVE A WAY OUT. WHAT'S SO BAD ABOUT THAT?
Bad (Fearless #13)
by Francine PascalGaia is genetically incapable of feeling fear. Gaia finally has Sam and he's everything she ever desired. But something or someone stands in the way of her true happiness.
Bad Actors (Slough House #8)
by Mick HerronMick Herron, &“the le Carré of the future&” (BBC), expands his world of bad spies with an even shadier cast of characters: the politicians, lobbyists, and misinformation agents pulling the levers of government policy. &“Confirms Mick Herron as the best spy novelist now working.&”—NPR's Fresh Air Now an Apple TV+ series starring Gary Oldman and Kristin Scott Thomas.In London's MI5 headquarters a scandal is brewing that could disgrace the entire intelligence community. The Downing Street superforecaster—a specialist who advises the Prime Minister's office on how policy is likely to be received by the electorate—has disappeared without a trace. Claude Whelan, who was once head of MI5, has been tasked with tracking her down. But the trail leads him straight back to Regent's Park itself, with First Desk Diana Taverner as chief suspect. Has Taverner overplayed her hand at last? Meanwhile, her Russian counterpart, Moscow intelligence's First Desk, has cheekily showed up in London and shaken off his escort. Are the two unfortunate events connected?Over at Slough House, where Jackson Lamb presides over some of MI5's most embittered demoted agents, the slow horses are doing what they do best, and adding a little bit of chaos to an already unstable situation . . . There are bad actors everywhere, and they usually get their comeuppance before the credits roll. But politics is a dirty business, and in a world where lying, cheating and backstabbing are the norm, sometimes the good guys can find themselves outgunned.
Bad Actors: The Instant #1 Sunday Times Bestseller (Slough House Thriller #8)
by Mick Herron*NOW A MAJOR TV SERIES STARRING GARY OLDMAN*The eighth book in the critically acclaimed and bestselling Slough House THRILLER series by Mick Herron, who has been called 'Britain's finest living thriller writer' [Sunday Express]'Herron is at the summit of a new golden age of spy fiction' Sunday TimesPOLITICS IS A DANGEROUS GAMEIn MI5 a scandal is brewing and there are bad actors everywhere.A key member of a Downing Street think-tank has disappeared without a trace. Claude Whelan, one-time First Desk of MI5's Regent's Park, is tasked with tracking her down. But the trail leads straight back to Regent's Park HQ itself, with its chief, Diana Taverner, as prime suspect. Meanwhile her Russian counterpart has unexpectedly shown up in London but has slipped under MI5's radar.Over at Slough House, the home for demoted and embittered spies, the slow horses are doing what they do best: adding a little bit of chaos to an already unstable situation.In a world where lying, cheating and backstabbing is the norm, bad actors are bending the rules for their own gain. If the slow horses want to change the script, they'll need to get their own act together before the final curtain.'Herron has certainly devised the most completely realised espionage universe since that peopled by George Smiley' The Times'Herron's novels are genuinely thrilling' Daily Telegraph'Britain's finest living thriller writer' Sunday Express(P) 2022 Hodder & Stoughton
Bad Actors: The Instant #1 Sunday Times Bestseller
by Mick Herron*Pre-order Clown Town, the ninth novel in Mick Herron's Slough House series, now**Now an award-winning Apple TV+ series starring Gary Oldman, Kristin Scott Thomas and Jack Lowden*THE INSTANT #1 SUNDAY TIMES BESTSELLER'A pitch-perfect espionage thriller' Sunday Times'The foremost living spy novelist in the English language' New Statesman****In MI5 a scandal is brewing and there are bad actors everywhere.A key member of a Downing Street think-tank has disappeared without a trace. Claude Whelan, one-time First Desk of MI5's Regent's Park, is tasked with tracking her down. But the trail leads straight back to Regent's Park HQ itself, with its chief, Diana Taverner, as prime suspect. Meanwhile her Russian counterpart has unexpectedly shown up in London but has slipped under MI5's radar.Over at Slough House, the home for demoted and embittered spies, the slow horses are doing what they do best: adding a little bit of chaos to an already unstable situation.In a world where lying, cheating and backstabbing is the norm, bad actors are bending the rules for their own gain. If the slow horses want to change the script, they'll need to get their own act together before the final curtain.*Includes the short story Standing by the Wall: A Slough House Interlude*'This is entertainment of the highest class' Literary Review'The man is a genius' The Spectator
Bad Acts and Guilty Minds: Conundrums of the Criminal Law
by Leo KatzLeo Katz seeks to understand the basic rules and concepts underlying the moral, linguistic, and psychological puzzles that plague the criminal law. This book revives the mind, it challenges superficial analyses.
Bad Acts and Guilty Minds: Conundrums of the Criminal Law (Studies in Crime and Justice)
by Leo KatzWith wit and intelligence, Leo Katz seeks to understand the basic rules and concepts underlying the moral, linguistic, and psychological puzzles that plague the criminal law. "Bad Acts and Guilty Minds . . . revives the mind, it challenges superficial analyses, it reminds us that underlying the vast body of statutory and case law, there is a rationale founded in basic notions of fairness and reason. . . . It will help lawyers to better serve their clients and the society that permits attorneys to hang out their shingles."—Edward N. Costikyan, New York Times Book Review
Bad Advice: How to Survive & Thrive in an Age of Bullshit
by Dr. Venus NicolinoLos Angeles Times #1 BestsellerUSA Today Bestselling BookOver motivational messages? Sick AF of inspirational quotes? Done with the shiny happy bad advice that gets you nowhere? Well, heads up: you’re about to get a shitload of Good Advice.In Bad Advice, relationship expert Dr. Venus Nicolino—a.k.a. Dr. V—takes a blowtorch to the shrink-wrapped, “feel good” BS that passes for self-help these days. When you’re heartbroken, what do you hear? You can’t love anyone until you love yourself. When someone’s hurt you? Nobody can make you feel bad without your permission. When you’re just a little too positive? Expectations lead to disappointment. Pop culture noise gives Bad Advice the varnish of truthiness and inspiration. But it’s not truth; it’s not inspiration. It’s bullshit. And at its root, all Bad Advice operates off the same lie: Emotions are optional. In Bad Advice, Dr. V delivers a bracing truth serum, in the form of Good Advice—an antidote to the bullshit, from “Just Be Yourself” to “Live Each Day Like It’s Your Last,” that teaches you to live your life in a way that honors who you are, what you need, and how you feel.Smart and irreverent, Dr. V fuses the brains and insight of a nerdy Ph.D. with the heart of a doting Italian Mother and the artful profanity of a Philly trucker. Dr. V’s signature combination of humor, hard science, and heartmake Bad Advice an iconoclastic course-correction like no other. A fiercely sharp wake-up call that tackles some of self-help’s most damaging truisms, Bad Advice is a never shy guide to tapping into your full potential.