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This book is an annual publication entering its 40th year. The series represents current trend and issues in the field of educational communications and technology, journals and other periodicals associated with the field, and the academic programs that prepare instructional technology professionals. Springer has been the publisher for the series, in cooperation with the Association for Educational Communications and Technology, for the past four years. Volume 39 will feature a section on Information Studies, in addition to updated information about programs and a new ranking of the top academic degree programs in the field of Learning, Design, and Technology.
This book embraces both traditional and advanced ceramics produced from synthetic or deeply transformed natural raw materials. Following the path of ceramic innovation, this introduction explains electric properties of ceramic conductors, like high-temperature superconductors, reflects on the interaction of material and electromagnetic radiation, presents the importance of voids and defects in the material, and provides an outlook on most recent developments in the field of ceramics, such as smart or self-healing materials . It provides a quick grasp of the main points of ceramic thinking and is an ideal starting point for students in the field of chemistry, materials science or solid state physics.
There has been much attention paid to the idea of Smart Cities as researchers have sought to define and characterize the main aspects of the concept, including the role of creative industries in urban growth, the importance of social capital in urban development, and the role of urban sustainability. This book develops a critical view of the Smart City concept, the incentives and role of governments in promoting the development of Smart Cities and the analysis of experiences of e-government projects addressed to enhance Smart Cities. This book further analyzes the perceptions of stakeholders, such as public managers or politicians, regarding the incentives and role of governments in Smart Cities and the critical analysis of e-government projects to promote Smart Cities' development, making the book valuable to academics, researchers, policy-makers, public managers, international organizations and technical experts in understanding the role of government to enhance Smart Cities' projects.
Chronic obstructive pulmonary disease (COPD) is a multi-component condition that results in increasingly limited airflow, usually associated with an abnormal inflammatory response of the lung. It constitutes a major public health burden worldwide, while only very few effective therapies are available. This book provides a comprehensive overview of the development of Onbrez Breezhaler, a newly approved once-daily inhaled β2 agonist for the treatment of COPD. It reviews the current pharmacotherapy for COPD and discusses topics such as the chemical design and the pre-clinical pharmacology of the molecule, the early clinical development, the INHANCE study (which provides a successful example of the use of an adaptive design in the confirmatory setting) and the Phase III clinical efficacy study, as well as the history and performance of the Breezhaler device. Finally, a list of emerging targets is included that could well offer future treatment options for COPD.
This book is a great foundation for exploring functional-first programming and its role in the future of application development. The best-selling introduction to F#, now thoroughly updated to version 4. 0, will help you learn the language and explore its new features. F# 4. 0 is a mature, open source, cross-platform, functional-first programming language which empowers users and organizations to tackle complex computing problems with simple, maintainable and robust code. F# is also a fully supported language in Visual Studio and Xamarin Studio. Other tools supporting F# development include Emacs, MonoDevelop, Atom, Visual Studio Code, Sublime Text, and Vim. Beginning F#4. 0 has been thoroughly updated to help you explore the new features of the language including: Type Providers Constructors as first-class functions Simplified use of mutable values Support for high-dimensional arrays Slicing syntax support for F# lists Reviewed by Don Syme, the chief architect of F# at Microsoft Research, Beginning F#4. 0 is a great foundation for exploring functional programming and its role in the future of application development. What you'll learn A deep familiarity with the tenets and advantages of functional programming. How to understand F# 4. 0's concise and elegant syntax. How to develop for real-world scenarios using functional programming and F# 4. 0. How to develop realistic applications through a comprehensive tutorial-based approach. How to learn imperative and concurrent programming techniques within the functional programming paradigm. Who this book is for Beginning F# 4. 0 is for anyone interested in state-of-the-art programming for solving real-world problems. It serves as an excellent introduction to F# for programmers of all backgrounds including C#, Java and VB as well as for lovers of Python, Ruby and other dynamic languages. If you are already familiar with functional programming, you'll find Beginning F#4. 0 a great introduction to the language itself. If you are new to the function programming arena, this book will also serve as a superb reference to FP in general and F# specifically.
Quality Management in Reverse Logistics intends to develop, collect, examine and evaluate a number of quality management (QM) tools and techniques, which can be applied in practice in order to understand, review and improve any closed-loop supply chain process. In other words, the book aims to examine the existing relationship between various well-developed and thoroughly studied quality issues, such as QM, quality assurance, standardization of processes and statistical quality control and the emerging research area of reverse logistics. Quality Management in Reverse Logistics contains modeling and quantitative methods that could be used by practitioners and academics in the reverse logistics industry, as well as a thorough description of QM tools and techniques. The book leads the potential reader to broaden their scope of thinking and acting in the new, promising area of reverse logistics, where QM can be applied.
If you have ever wondered how we get from the awesome impersonality of the Big Bang universe to the point where living creatures can start to form, and evolve into beings like you, your friends and your family, wonder no more. Steve Miller provides us with a tour through the chemical evolution of the universe, from the formation of the first molecules all the way to the chemicals required for life to evolve. Using a simple Hydrogen molecule - known as H-three-plus - as a guide, he takes us on a journey that starts with the birth of the first stars, and how, in dying, they pour their hearts out into enriching the universe in which we live. Our molecular guide makes its first appearance at the source of the Chemical Cosmos, at a time when only three elements and a total of 11 molecules existed. From those simple beginnings, H-three-plus guides us down river on the violent currents of exploding stars, through the streams of the Interstellar Medium, and into the delta where new stars and planets form. We are finally left on the shores of the sea of life. Along the way, we meet the key characters who have shaped our understanding of the chemistry of the universe, such as Cambridge physicist J.J. Thomson and the Chicago chemist Takeshi Oka. And we are given an insider's view of just how astronomers, making use of telescopes and Earth-orbiting satellites, have put together our modern view of the Chemical Cosmos.
The latest edition of the single most authoritative guide on dimensional modeling for data warehousing! Dimensional modeling has become the most widely accepted approach for data warehouse design. Here is a complete library of dimensional modeling techniques-- the most comprehensive collection ever written. Greatly expanded to cover both basic and advanced techniques for optimizing data warehouse design, this second edition to Ralph Kimball's classic guide is more than sixty percent updated. The authors begin with fundamental design recommendations and gradually progress step-by-step through increasingly complex scenarios. Clear-cut guidelines for designing dimensional models are illustrated using real-world data warehouse case studies drawn from a variety of business application areas and industries, including: * Retail sales and e-commerce * Inventory management * Procurement * Order management * Customer relationship management (CRM) * Human resources management * Accounting * Financial services * Telecommunications and utilities * Education * Transportation * Health care and insurance By the end of the book, you will have mastered the full range of powerful techniques for designing dimensional databases that are easy to understand and provide fast query response. You will also learn how to create an architected framework that integrates the distributed data warehouse using standardized dimensions and facts. This book is also available as part of the Kimball's Data Warehouse Toolkit Classics Box Set (ISBN: 9780470479575) with the following 3 books: The Data Warehouse Toolkit, 2nd Edition (9780471200246) The Data Warehouse Lifecycle Toolkit, 2nd Edition (9780470149775) The Data Warehouse ETL Toolkit (9780764567575)
The uncontrolled utilization of natural resources to supply to the water demands of the ever-growing population has brought about worldwide scarcity. The supply shortage has resulted in conflicts between countries, created prolonged drought, closing of industrial units, shifting of local inhabitants etc. The abnormality in climatic patterns due to global warming has only enhanced the uncertainties. Unregulated discharge of waste water into fresh water resources is also polluting the available water resources and making them non-utilizable. That is why the discrepancy between water supply and demand is slowly but steadily becoming a problem, which may lead to conflict and inequality all over the world. The present investigation is an attempt to find the impact of urbanization in the face of climatic uncertainties on water shortage or scarcity. How is climate responsible? What urbanization factors have an influence on the extent of shortages? What is the role of the socio-economic status of the inhabitants? Industrialization? Consumption pattern? Each of the causes and effects were analyzed with the help of data from a climate model, which was then fed into a hydrologic model. The hydrologic output data was then put into various other novel simulation platforms to predict the uncertainties that can be caused by urbanization in various sectors of the regions of interest. The impact was calculated based on IPCC recommended climatic and five distinct urbanization scenarios. The study results will help to predict what is in store of those living in the developing countries. Possible mitigation measures are also discussed.
Creating a successful and distinctive approach to learning and teaching at scale is a challenge facing all universities. This brief presents the Self-Organizing University (SOU), a transformational whole-of-organization solution for the design, delivery, and evaluation of learning and teaching in all its forms. It describes the elements of the SOU approach along with the implementation process and expected outcomes. It also explains the rationale and research base for each element of the model and how they are connected to create a university-wide model of learning and teaching. It includes guidance for anyone responsible for institutional improvement in the learning and teaching space.
This book focuses on how instruction affects English learners' use of Theme and thematic progression (thematic organization). While thematic organization in learner English has been extensively studied, little research has been done to investigate the effects of instruction on the use of Theme and thematic progression. Adopting a Systemic Functional Grammar approach, this study explores how a ten-week instruction on thematic organization affects Chinese college students' use of Theme and thematic progression by comparing their English essays before and after the instruction, with native-speaker essays as the research baseline. Second-language acquisition researchers, curriculum developers and foreign language teachers will find this book useful as it not only presents a clear and detailed report of how Chinese college students learn to make better thematic choices, but also provides a well-developed instructional package on Theme and thematic progression.
These conference proceedings focus on the topic of decision-making under uncertainty, smart decisions, management simulation and their applications in operations management for power and logistics companies. The Beijing University of Chemical Technology organized IFDS2015, the 3rd International Forum on Decision Sciences, with this year's theme being "Decision Making under Uncertainty". The proceedings collect 7 selected papers presenting the cutting-edge modeling and solution methods and including numerous practical case studies, which are of interest for researchers and practitioners alike. Teachers, students and practitioners working in the fields of decision science, operations research, management science and engineering will benefit from the valuable findings presented in this book.
With exponentially increasing population across the globe and shrinking resources, the concern of food security is looming large over the world community. To catch up with the fierce pace of growth in all the sectors of development, ensuring uninhibited availability of food resources is a prime agenda. The growing global demand for food, feed, fiber and bio-based renewable materials, such as bio-fuels, is changing the conditions for genetic resources development and bio-resource production worldwide. The crucial role in ensuring food security is played by the agro-based industries and enterprises. Advances in plant genetic resources coupled with traditional knowledge of the local tribes and native practices facilitate achievement of food security.
This book deals with the theoretical, methodological, and empirical implications of bounded rationality in the operation of institutions. It focuses on decisions made under uncertainty, and presents a reliable strategy of knowledge acquisition for the design and implementation of decision-support systems. Based on the distinction between the inner and outer environment of decisions, the book explores both the cognitive mechanisms at work when actors decide, and the institutional mechanisms existing among and within organizations that make decisions fairly predictable. While a great deal of work has been done on how organizations act as patterns of events for (boundedly) rational decisions, less effort has been devoted to study under which circumstances organizations cease to act as such reliable mechanisms. Through an empirical strategy on open-ended response data from a survey among junior judges, the work pursues two main goals. The first one is to explore the limits of "institutional rationality" of the Spanish lower courts on-call service, an optimal scenario to observe decision-making under uncertainty. The second aim is to achieve a better understanding of the kind of uncertainty under which inexperienced decision-makers work. This entails exploring the demands imposed by problems and the knowledge needed to deal with them, making this book also a study on expertise achievement in institutional environments. This book combines standard multivariate statistical methods with machine learning techniques such as multidimensional scaling and topic models, treating text as data. Doing so, the book contributes to the collaboration between empirical social scientific approaches and the community of scientists that provide the set of tools and methods to make sense of the fastest growing resource of our time: data.
This volume follows the successful book, which has helped to introduce and spread the Philosophy of Chemistry to a wider audience of philosophers, historians, science educators as well as chemists, physicists and biologists. The introduction summarizes the way in which the field has developed in the ten years since the previous volume was conceived and introduces several new authors who did not contribute to the first edition. The editors are well placed to assemble this book, as they are the editor in chief and deputy editors of the leading academic journal in the field, Foundations of Chemistry. The philosophy of chemistry remains a somewhat neglected field, unlike the philosophy of physics and the philosophy of biology. Why there has been little philosophical attention to the central discipline of chemistry among the three natural sciences is a theme that is explored by several of the contributors. This volume will do a great deal to redress this imbalance. Among the themes covered is the question of reduction of chemistry to physics, the reduction of biology to chemistry, whether true chemical laws exist and causality in chemistry. In addition more general questions of the nature of organic chemistry, biochemistry and chemical synthesis are examined by specialist in these areas.
This book brings together state-of-the-art research on successful aging in Asian populations and highlights how the factors that contribute to successful aging differ from those in the West. It examines the differences between the Asian and Western contexts in which the aging process unfolds, including cultural values, lifestyles, physical environments and family structures. In addition, it examines the question of how to add quality to longer years of life. Specifically, it looks at ways to promote health, preserve cognition, maximize functioning with social support and maintain emotional well-being despite inevitable declines and losses. Compared to other parts of the world, Asia will age more quickly as a result of the rapid socioeconomic developments leading to rising longevity and historically low fertility rates in some countries. These demographic forces in vast populations such as China are expected to make Asia the main driver of global aging in the coming decades. As a result, researchers, professionals, policymakers, as well as the commercial sector, in both East and West, are increasingly interested in gaining a deeper understanding of aging in Asia.
The rich and diverse contributions to this volume span a wide variety of disciplines, from psychology and philosophy to neuroscience, by some of the most influential scholars in the emerging science of personal wisdom. As such, it is a collection of essential readings and the first publication to integrate both the spiritual and pragmatic dimensions of personal wisdom. The content of the book goes beyond speculative theory to present a wealth of scientific research currently under way in this expanding field. It also describes numerous promising methods now being deployed in the quest for scientific knowledge of the elusive, yet critical, phenomenon of personal wisdom. The book is an excellent introduction to the field for novice researchers as well as a stimulating and enlightening resource for established experts. Its broad appeal makes it a vital addition to the libraries of academics and practitioners in many disciplines, from developmental psychology to gerontology and from philosophy to contemplative religious traditions such as Buddhism.
This volume provides a nuanced empirical assessment of the extent to which the academic profession is internationalized at the beginning of the 21st century. It indicates which are the most internationalized academic activities, and focuses on specific topics such as physical mobility for study or professional purposes, teaching abroad or in another language, research collaboration with foreign colleagues, and publication and dissemination outside one's native country or in another language. It places the main theme in the wider context of the history of higher education's internationalization. It provides explanations on what drives and deters academics from international activity, and documents some of the consequences that internationalization has on academic work and productivity. This study is based on a survey of 25,000 academics working at higher education institutions in 18 countries and Hong Kong on five continents. Comparing data from the 1992 Carnegie International study to the 2007 CAP survey, relying on respondents' perceptions of change, and comparing different academic generations, it offers valuable insights on changes in the internationalization of the academy.
The Socioecological Educator: A 21st Century Renewal of Physical, Health,Environment and Outdoor Educationby Amy Cutter-Mackenzie Justen O'Connor Ruth Jeanes Trent Brown Laura Alfrey Brian Wattchow
This volume offers an alternative vision for education and has been written for those who are passionate about teaching and learning, in schools, universities and in the community, and providing people with the values, knowledge and skills needed to face complex social and environmental challenges. Working across boundaries the socio-ecological educator is a visionary who strives to build community connections and strengthen relationships with the natural world. The ideas and real-world case studies presented in this book will bring that vision a step closer to reality.
Autoimmune Disease: Pathogenesis, Genetics, Immunotherapy, Prophylaxis and Principles for Organ Transplantationby Duncan Dartrey Adams Christopher Dartrey Adams
This book describes how the Jerne-Burnet Forbidden Clone Theory and the Adams-Knight H Gene Theory, solved the pathogenesis and genetics of the autoimmune diseases showing how specific immunotherapy and prophylaxis can be developed. Furthermore, Ebringer's discovery of two microbial triggers of autoimmune diseases is described and the conclusion drawn that all autoimmune diseases have microbial triggers, so will be preventable by the finding of the triggers and vaccination against them.
This book addresses environmental and climate change induced migration from the vantage point of migration studies, offering a broad spectrum of approaches for considering the environment/climate/migration nexus. Research on the subject is still frequently narrowed down to climate change vulnerability and the environmental push factor. The book establishes the interconnections between societal and environmental vulnerability, and migration and capability, allowing appreciation of migration in the frame of climate as a case of spatial and social mobility, that is, as a strategy of persons and groups to deal with a grossly unequal distribution of life chances across the world. In their introduction, the editors fan out the current debate and state the need to transcend predominantly policy-oriented approaches to migration. The first section of the volume focuses on "Methodologies and Methods" and presents very distinct approaches to think climate induced migration. Subsequent chapters explore the sensitivity of existing migration flows to climate change in Ghana and Bangladesh, the complex relationship between migration, demographic change and coping capacities in Canada, methodological challenges of a household survey on the significance of migration and remittances for adaptation in the Hindu Kush region and an econometric study of the aftermath of the 1998 floods in Bangladesh. The second part, "Areas of Concern: Politics and Human Rights", deepens the analysis of discourses as well as of the implications of proposed and implemented policies. Contributors discuss such topics as environmental migration as a multi-causal problem, climate migration as a consequence in an alarmist discourse and climate migration as a solution. A study of an integrated relocation program in Papua New Guinea is followed by chapters on the promise and the flaws of planned relocation policy, global policy on protection of environmental migrants including both internally displaced peoples and those who cross international borders. A concluding chapter places human agency at centre stage and explores the interplay between human rights, capability and migration.
This book is focused on geometrical models of robot mechanisms. Rotation and orientation of an object are described by Rodrigues's formula, rotation matrix and quaternions. Pose and displacement of an object are mathematically dealt with homogenous transformation matrices. The geometrical robot model is based on Denavit Hartenberg parameters. Direct and inverse model of six degrees of freedom anthropomorphic industrial robots are also presented.
Iron is essential for the growth of most bacteria because it serves as a cofactor for vital enzymes and for the components of the electron transport chain. Moreover, Iron plays an important role in bacterial pathogenicity; in fact, the iron transport systems in bacteria works as target for designing novel antibiotics. Because iron is not soluble under aerobic conditions, bacteria have had to find ways to overcome iron deficiency. One of them is producing an iron-chelating small organic molecule called siderophore. Indeed, most bacteria and fungi produce structurally and chemically diverse siderophores which are transported back to the cytoplasm using complex energy dependent transport systems. Escherichia coli and Pseudomonas were the first ones to be tested; however, nowadays iron transport systems have been investigated in many other bacteria. Iron Uptake in Bacteria with Emphasis on E. coli and Pseudomonas reviews the recent advancements in the field of iron transport systems in bacteria. Chapter 1 is dedicated to Dr. Dick van der Helm's contribution to the field of siderophore biology. It then describes and discusses the structural advances in the components and the mechanism of siderophore mediated iron transport systems in E.coli. Chapter 2 details the variety of iron transport and iron regulatory systems of both gram negative and gram positive bacteria. Finally, chapter 3 describes the iron transport systems of Pseudomonas. This book is aimed at researchers in the fields of iron metabolism in multiple organisms, and to those who are interested in studying iron transport systems of bacteria. It appeals also to scientists researching structure and function relationship of proteins.
The terrorist use of diseases as bioweapons has been one of the major security concerns in recent years, particularly after the anthrax letter attacks in the USA in 2001. This uncertain threat of intentional outbreaks of diseases exists side by side with the constantly changing very real threat from diseases, epidemics and pandemics as recently illustrated by the H1N1 influenza pandemic, SARS, and H5N1 bird influenza events. This publication contains case studies on the public health planning for (un)usual disease outbreaks for 11 large and small countries with a focus on South Eastern Europe. In many countries, military entities traditionally play an important role in emergency response to disease outbreaks. In smaller countries, very little exists, however, in terms of specific biopreparedness efforts (in both the military and civilian area), which is at least partly due to a relatively low bioterrorism threat perception, and serious resource constraints. The uncertainty associated with the bioterrorism threat makes public health preparedness planning for such events politically and financially very difficult. The similarity of responding to bioterrorism events and natural disease outbreaks from a public health point of view suggests the merit of looking at biopreparedness as a part of overall health emergency planning, not as a separate effort.
The integrated theory of dynamic interpretation set out here will be a surprise to advanced researchers in linguistics. It combines classical formal semantics and modern dynamic semantics without altering the fundamental paradigm. At the book's core lies a pragmatically motivated notion of a dynamic conjunction of meanings, an idea that is worked out in full formal detail. This is applied to linguistic phenomena that involve anaphora, quantification and modality. The author demonstrates that in each area of application existing data can be neatly combined with new dynamic insights, but more importantly, there is a genuine further pay-off: the work generates treatments of phenomena that were not initially intended, with functional readings of pronouns and quantifiers, 'Hob-Nob' sentences, and insights into what we now call 'Pierce's Puzzle'. The outcome of a decade of work by the Amsterdam School of dynamic semantics, this volume condenses and reflects upon a vital body of research.