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Drogadicto Americano: una autobiografía
by Brett DouglasMi nombre es Brett. Soy un hombre con educación universitaria que alguna vez fue esposo durante 26 años, con dos hijos, tres negocios y una gran casa con una cerca blanca de verdad. También soy un adicto a las drogas. Y tengo una historia que contar. Mi relato lo tiene todo: sexo, muerte, dolor, ateísmo, Dios, cárcel, matrimonio, divorcio, herejía, homosexualidad, física, accidentes de tráfico, ciencias de la computación, videojuegos, palillos de canela, Barry Manilow, Nine Inch Nails, pornografía, senos, tampones usados, strippers, enfermedades venéreas, aborto, prostitutas, SIDA, racismo, suicidio, infidelidad, desnudez pública, antisemitismo, marihuana, alcohol, casas de empeño, traficantes de drogas, agujas, ácido, éxtasis, crack, heroína, analgésicos, abstinencia, intervenciones, rehabilitaciones, manipulación de productos, furia en la carretera, vandalismo, abuso a ancianos, profanación de tumbas, incendio intencional, robo de identidad, allanamiento de morada, robo a mano armada y asesinato. Pero, lo más importante, se trata de la desesperación de la adicción y la certeza absoluta de que se puede superar. La recuperación no es simplemente abstinencia, sino un proceso de madurez. Pasé toda mi vida buscando la clave para la sobriedad a largo plazo. Me gustaría compartir contigo lo que he aprendido.
Drug Delivery Systems for Musculoskeletal Tissues
by Sumit MurabMusculoskeletal tissues are hard to heal if damaged by disease or trauma. If damaged, they cause pain and hinder regular movements of our bodies. Drug delivery systems that can be used for healing and regenerating these tissues need to be specialized to bear physiological loading on these tissues while helping in controlled release of drug or biomolecules for healing the tissue. This book discusses the pathology of orthopaedic diseases and the requirements of local drug delivery platforms that can help in the treatment of the pathology as well as regeneration of the tissue. The book also discusses in detail the mechanical properties and support that these systems provide to the damaged musculoskeletal tissues and how long-term healing and regeneration is possible. This is an ideal book for students, postdoctoral fellows and faculty at academic universities, and industry professionals who are working on drug delivery, orthopaedic diseases, tissue engineering, and regenerative medicine.
Drug Resistance in Cancer: Mechanisms and Strategies
by Sameer Ullah Khan Fayaz MalikThis book tries to emphasize the mechanisms associated with the resistance towards various anti-cancer therapies The focus has been given to the role of cancer stem cells, immune cells, and the multiway impact of tumor microenvironment in drug resistance. The book delves into the role of epigenetic alterations, autophagy, intracellular compartments, and the impact of gut microbiome on therapeutic resistance. Each chapter of the book has elaborated on these aspects that are exclusively or mutually driving the therapeutic non-responsiveness towards various current clinical candidates. In addition to that the book has also discussed novel strategies to overcome the therapeutic challenge by employing combinatorial therapies that can prove to be useful and effective. Overall the book reflects on the current treatment challenges, futuristic strategies and new research initiatives that explore novel treatment options.
Dry Lands
by Elizabeth Anne Martins&“A testament to the power of hope and motherhood in the worst of situations.&”—KirkusAfter a cataclysmic flood submerges half the world underwater, cannibalistic gangs and corrupt encampments become a constant threat to the remaining dry lands. Liv and her precocious three-year-old son Milo are some of the lucky ones who have survived.With the company of a lonely horse seeking a loving home, Liv is determined to protect Milo from the encampments, even if it means destroying what little is left of civilization. Amidst it all, she learns to embrace love and her own worth. Dry Lands is a gripping journey showcasing the resilience of humanity, parenthood, and the sacrifices we make for our children.FLAME TREE PRESS is the imprint of long-standing Independent Flame Tree Publishing, dedicated to full-length original fiction in the horror and suspense, science fiction & fantasy, and crime / mystery / thriller categories. The list brings together fantastic new authors and the more established; the award winners, and exciting, original voices. Learn more about Flame Tree Press at www.flametreepress.com and connect on social media @FlameTreePress.
Dungeoneer Adventures 3: Quest for the Wishing Stone (Dungeoneer Adventures #3)
by Ben Costa James ParksThe Last Kids on Earth gets a fantasy twist in this third book in the highly illustrated middle grade Dungeoneer Adventures series following Coop and his friends as they sneak along on their professors&’ quest to save Eem.Hero dungeoneer Shane Sandar has been missing for weeks, and the professors at Dungeoneer Academy fear the worst: that he&’s met a terrible fate at the hands of the villainous exiles. When Coop Cooperson and his best buds on the Green Team discover their professors are taking a dangerous voyage to try and rescue Shane—and closing Dungeoneer Academy in the process—they know they can&’t let their professors go alone, so they secretly tag along. It&’s not long before the professors are captured, which leaves it up to Coop, Oggie, Mindy, Daz, and unlikely new ally Zeke to try to rescue Shane Sandar, help their beloved professors, and save the Land of Eem from the terrible fate the exiles are planning. But can a ragtag group of junior dungeoneers stop a group whose leader is pursuing the power of the Wishing Stone, the most powerful magic in all the land?
Dungeons & Dragons: Dungeon Academy: Last Best Hope (Dungeons & Dragons: Dungeon Academy)
by Madeleine RouxFrom New York Times bestselling author Madeleine Roux and acclaimed artist Tim Probert comes the thrilling third novel in the original Dungeons & Dragons middle grade series!Zelli Stormclash and the Danger Club have only one goal: save their friend Bauble from the evil clutches of Elgred Morbide. There’s only one problem—the evil machinations of Morbide’s selfish plots have come to a head, and the final battle for Dungeon Academy has already begun. Deep beneath the desert, a monstrous dracolich is about to be unleashed, an evil, undead dragon bent on revenge against everything in her path.Zelli is no longer on a rescue mission but a fated quest to save Dungeon Academy, Faerun, and all the Forgotten Realms. Our motley crew of heroes must rise to the occasion and wield the most important weapon an adventurer can carry: hope. Against impossible odds, the Danger Club—members old and new—must take one last stand together and fight like never before . . . till the very end.Join the Danger Club in this final tale of daring rescue, selfless sacrifice, and scale-raising adventure!
Dynamic Behavior of Soft and Hard Materials, Volume 2: Proceedings of 13th International Symposium on Plasticity and Impact Mechanics 2022 (Springer Proceedings in Materials #35)
by R. Velmurugan G. Balaganesan Naresh Kakur Krishnan KannyThis book comprises the select peer-reviewed proceedings of the 13th International Symposium on Plasticity and Impact Mechanics (IMPLAST) 2022. It aims to provide a comprehensive and broad-spectrum picture of the state-of-the-art research and development in diverse areas, such as constitutive relations, theories of plasticity, stress waves in solids, earthquake loading, high-speed impact problems, fire and blast loading, structural crashworthiness and failure, mechanics of penetration and perforation, among others. The contents focus on aspects of large deformations and failure of materials, including metals, composites, cellular, geomaterials, or concrete, and structures resulting from quasi-static earthquake, fire, impact, or blast loading. This book is a valuable resource for researchers and professionals working in academia and industry in the areas of mechanical, materials, and aerospace engineering.
Dynamic Positioning Systems: Class Guidance for DP Operators (Springer Series on Naval Architecture, Marine Engineering, Shipbuilding and Shipping #21)
by Fidaa KarkoriThe application of dynamic positioning (DP) systems has been expanded significantly not only in the number of DP vessels, but also in the range of applications and the advancement of DP technologies. In order to address various needs of the industry, the majority of leading Classification Societies (Class) have developed Class specific guidance relating to development, implementation, and use of dynamic positioning Systems (DP). This book provides generalised guidance adapted from various leading Classes, to provide DP professionals with a readily available source of information and guidance relating to the operation and use of DP systems. The book provides optional notations and technical specifics that reflect current industry practice and DP technologies. This book includes guidance relating to: • Enhanced system (EHS) notations to recognise design features beyond current DPS-series notations and to provide flexibility to owners and operators. • Station keeping performance (SKP) notations to recognise DP capability and to encourage robust design of the DP systems. • Increased level of detail on the technical requirements to help less experienced users.
Dynamics and Mechanisms Design for Technology Students: A Project-Based Approach (Synthesis Lectures on Mechanical Engineering)
by Anthony D´Angelo Jr.The book reviews the algebra, trigonometry, and basic calculus students need to be successful in solving problems. Next, a review of kinematics and Newton’s laws are discussed, and numerous examples are solved. Mechanisms include the slider crank, offset slider crank, gears and gear trains, belts and chains, and cams. A graphical and analytical approach is taken when covering slider crank mechanisms. The book uses vectors and Kennedy's theorem to solve a variety of included examples. Gears and gear trains as well as belts and chains are discussed. Finally, cams using graphical and analytical techniques are introduced. The concluding chapter gives multiple projects used in the class to capture the lectures and computer modeling using Excel and MATLAB.
E-Money and Monetary Policy Transmission
by WiriadinataA report from the International Monetary Fund.
Earls Trip (Earls Trip #1)
by Jenny HolidayTed Lasso meets Bridgerton for a 19th century spin on The Hangover in USA Today bestselling author Jenny Holiday&’s laugh-out-loud bromantic comedy featuring three Regency-era Earls on their annual trip – ride-or-die buddies offering one another unconditional support in everything from Lady problems to family woes."One of the best historical romances I've read in years. I truly felt like the characters were falling in love." —Julia Quinn, bestselling author of the Bridgerton novels Even an earl needs his ride-or-dies, and Archibald Fielding-Burton, the Earl of Harcourt, counts himself lucky to have two. The annual trip that Archie takes with his BFFs Simon and Effie holds a sacred spot in their calendars. This year Archie is especially eager to get away until an urgent letter arrives from an old family friend, begging him to help prevent a ruinous scandal. Suddenly the trip has become earls-plus-girls, as Archie&’s childhood pals, Clementine and Olive Morgan, are rescued en route to Gretna Green. This…complicates matters. The fully grown Clementine, while as frank and refreshing as he remembers, is also different to the wild, windswept girl he knew. This Clem is complex and surprising—and adamantly opposed to marriage. Which, for reasons Archie dare not examine too closely, he finds increasingly vexing. Then Clem makes him an indecent and quite delightful proposal, asking him to show her the pleasures of the marriage bed before she settles into spinsterhood. And what kind of gentleman would he be to refuse a lady?
Early Childhood and Digital Media (Elements in Child Development)
by null Rachel Barr null Heather Kirkorian null Sarah Coyne null Jenny RadeskyScreen time, defined as estimates of child time spent with digital media, is considered harmful to very young children. At the same time, the use of digital media by children under five years of age has increased dramatically, and with the advent of mobile and streaming media can occur anywhere and at any time. Digital media has become an integral part of family life. Imprecise global screen time estimates do not capture multiple factors that shape family media ecology. In this Element, the authors discuss the need to shift the lens from screen time measures to measures of family media ecology, describe the new Dynamic, Relational, Ecological Approach to Media Effects Research (DREAMER) framework, and more comprehensive digital media assessments. The authors conclude this Element with a roadmap for future research using the DREAMER framework to better understand how digital media use is associated with child outcomes.
Early English Queens, 850–1000: Potestas Reginae (Lives of Royal Women)
by Matthew FirthThis book offers a comprehensive, biography-led examination of queenship in England between 850 and 1000, tracing the development of the queen’s role from bed companion to institutional office.The period 850–1000 is critical to the development of English queenship. In the aftermath of viking invasion, the kings of Wessex expanded their hegemony over neighbouring regions, gradually establishing themselves as the kings of England. Parallel to this broad narrative of political change is the lesser-known story, told in this book, of the royal women who took part in it. The lives of three remarkable women – Æthelflæd, Lady of the Mercians, and the West Saxon consorts Eadgifu and Ælfthryth – are central to the story, here retold through the careful analysis and reappraisal of source documents. These biographies set the stage for detailed study of the agency and advocacy of all women who held queenly office in England between 850 and 1000, as well as their legacies and reception by later generations.Early English Queens, 850–1000 gives important insights into the role women played in the first 150 years of the West Saxon dynasty, offering a compelling narrative that will appeal to students and scholars of early medieval England and royal studies.
Early Modern Atlantic Cities (Elements in Global Urban History)
by null Mariana Dantas null Emma HartThe Atlantic World was an oceanic system circulating goods, people, and ideas that emerged in the late fifteenth and early sixteenth century. European imperialism was its motor, while its character derived from the interactions between peoples indigenous to Europe, the Americas, and Africa. Much of the everyday workings of this oceanic system took place in urban settings. By sustaining the connections between these disparate regions, cities and towns became essential to the transformations that occurred in this early modern era. This Element, traces the emergence of the Atlantic city as a site of contact, an agent of colonization, a central node in networks of exchange, and an arena of political contestation. Cities of the Atlantic World operated at the juncture of many of the core processes in a global history of capitalism and of rising social and racial inequality. A source of analogous experiences of division as well as unity, they helped shape the Atlantic world as a coherent geography of analysis.
Early Modern Genres of History (Early Modern Themes)
by Emil Nicklas Johnsen Ina Louise StovnerBringing together an international group of literary scholars, intellectual historians, and cultural historians, this book discusses history in its various forms, either as texts or images in the early modern period (1500–1800).Early Modern Genres of History explores different genres and representational modes regarded as history before history became a scientific discipline during the nineteenth century. It does not seek to show how the modern discipline of history as an academic study developed, but rather to examine the ways in which historical texts and images became part of a wider field of early modern knowledge formations. This volume demonstrates how history was connected to the developments in the public sphere, how antiquarian historians used genres in their work, how history evolved and functioned in the visual field, and how historical genres travelled across different contexts. Overall, Early Modern Genres of History reveals how the diversity of historical representations in the early modern period has contributed to the broader foundations of history as it is understood in the twenty-first century.This volume is of great use to upper-level undergraduates, postgraduates, and scholars interested in early modern Europe and the history of knowledge across both the history and literature disciplines.
Early Sobrieties: A Novel
by Michael Deagler"&“Just give me one more day,&” Monk says, and &“Early Sobrieties&” is such a wise and piercing book that we believe him."—Charlie Lee, The New York Times Book Review"Michael Deagler is the real deal." —Percival Everett, 2023 Windham Campbell Prize recipient and author of Dr. NoDon&’t worry about what Dennis Monk did when he was drinking. He&’s sober now, ready to rejoin the world of leases and paychecks, reciprocal friendships and healthy romances—if only the world would agree to take him back. When his working-stiff parents kick him out of their suburban home, mere months into his frangible sobriety, the 26-year-old spends his first dry summer couch surfing through South Philadelphia, struggling to find a place for himself in the throng of adulthood.Monk&’s haphazard pilgrimage leads him through a city in flux: growing, gentrifying, haunted by its history and its unrealized potential. Everyone he knew from college seems to be doing better than him—and most of them aren&’t even doing that well. His run-ins with former classmates, estranged drinking buddies, and prospective lovers challenge his version of events past and present, revealing that recovery is not the happy ending he&’d expected, only a fraught next chapter.Like a sober, millennial Jesus&’ Son, Michael Deagler&’s debut novel is the poignant confession of a recovering addict adrift in the fragmenting landscape of America&’s middle class. Shot through with humor, hubris, and hard-earned insight, Early Sobrieties charts the limbos that exist between our better and worst selves, offering a portrait of a stifled generation collectively slouching towards grace.
Earth: The Definitive Visual Guide, New Edition (DK Definitive Visual Encyclopedias)
by DKExplore and understand the natural and human wonders of our planetNow in its third edition, this landmark encyclopedia both celebrates our planet and explains the science underpinning the forces and processes that have made and shaped it. Artworks, photographs, terrain models, and maps are used in combination to capture the beauty and power of landscapes and natural events and to show their hidden sides, explaining for example how an earthquake is triggered and how burning fossil fuels is driving a climate emergency.Directory sections placed throughout the book provide systematic and in-depth reference guides to core scientific information, such as more than 100 types of rocks and minerals. Similar sections contain visual profiles of some of the undisputed wonders of the natural world, from the Andes and Himalayas to the Grand Canyon, Sahara Desert, and Amazon Rainforest.Thoroughly revised and updated to include new and spectacular landscape photography and capture the latest developments in fast-changing areas of geology and Earth science—including Earth history, climate change, and urban geography—this is an indispensable visual reference book for anyone who wants to understand how our planet works.
Eastern Caribbean Currency Union: Selected Issues (Imf Staff Country Reports)
by International Monetary Fund. Western Hemisphere Dept.A report from the International Monetary Fund.
Eastern Caribbean Currency Union: 2024 Staff Report for the 2024 Article IV Consultation on Common Policies of Member Countries of the Eastern Caribbean Currency Union-Press Release and Staff Report
by International Monetary Fund. Western Hemisphere Dept.A report from the International Monetary Fund.
Eating Disorder Group Therapy: A Collaborative Approach
by Carolyn Karoll Adina SilvermanThis is the only book that teaches clinicians how to run an effective, evidence-informed, and multi-disciplinary eating disorder group, incorporating psychoeducation, process group dynamics, and experiential elements.Whereas group therapy for eating disorders is widely used across many levels of care, the outpatient setting is uniquely poised to deliver effective, multi-disciplinary group therapy. The first part of this book offers practical guidance for conceiving, organizing, and initiating outpatient groups, equipping clinicians with the necessary tools to foster supportive and transformative environments. The second includes seven chapters that delve into the core themes of eating disorder recovery, featuring 60 activities and discussions empowering participants towards growth and resilience. This book teaches clinicians how to collaboratively lead groups to optimize cohesion and harness the collective strength of the group to facilitate change. It provides thorough rationale and psychoeducation for each group exercise and is complete with sample forms, worksheets, and handouts.Suitable for clinicians and students alike in the eating disorder field, this guide on how to successfully begin and run your own group is a necessary resource.
The EBMT Handbook: Hematopoietic Cell Transplantation and Cellular Therapies
by Anna Sureda Selim Corbacioglu Raffaella Greco Nicolaus Kröger Enric CarrerasThis Open Access new edition of the EBMT handbook with its new format, addresses the latest developments and innovations in hematopoietic cell transplantation and cellular therapy. Consisting of 94 chapters, it has been written by 210 leading experts in the field. Discussing all types of hematopoietic cell transplantation, including selection of stem cell sources, it also covers the indications for transplantation, the management of early and late complications as well as the new and rapidly evolving field of cellular therapies and new infections (COVID-19). This book provides an unparalleled description of current practices to enhance readers’ knowledge and practice skills.
Echo Murder (Wilde Investigations)
by Laura LaaskoIn this new paranormal mystery from the author of Fallible Justice, an investigator looks into multiple murders—of the same man . . . When private investigator Yannia Wilde returns to the conclave where she grew up—and to the deathbed of her father, the conclave&’s Elderman—she is soon drawn back into the Wild Folk way of life, and into a turbulent relationship with Dearon, her betrothed. Back in London, Tim Wedgebury is surprised when police appear on his doorstep with a story about how he was stabbed in the West End. His body disappeared before the paramedics&’ eyes. Given that Tim is alive and well, the police chalk the first death up to a prank. But when Tim &“dies&” a second time, DI Jamie Manning calls Yannia. To assist with the case, she must return to the life she built in Old London—but as Yannia considers where her loyalties lie, will this trip to the city be her last?
ECMO - Leitfaden für Pflegende
by Birgit Heinze Daniele CamboniDieses Buch richtet sich an Pflegende auf der Intensivstation und ist ein Leitfaden für die Betreuung von Patienten mit extrakorporaler Membranoxygenierung, kurz ECMO. Diese spezielle Therapie ist ein expandierendes Verfahren, welches gerade in den letzten Jahren in Deutschland eine breite Anwendung findet. Die erfahrenen Autoren sind Spezialisten auf dem Gebiet und bieten Fachwissen auf höchstem Niveau in verständlicher Sprache. Lernen Sie alles Relevante für eine gute und sichere Pflege Ihrer Patienten!
Eco-Welfare and the Energy Transition: Themes and Debates for an Emerging Interplay
by Lorenzo De VidovichThis book provides a comprehensive overview of the emerging interplay that runs between energy – seen as a basic need and a providential material service from the viewpoint of welfare studies – and eco-welfare, seen as an emerging analytical and policy paradigm that hold together the social crisis on the one hand, and the ecological crisis, on the other hand. At a time of energy transition, the interplay between the theoretical framework of eco-welfare and the topic of energy supply is little explored, and therefore, this book fills a need in the literature by providing a comprehensive framework to navigate this emerging relationship. Such a framework is strengthened by insights on energy poverty and renewable energy communities, identified as cornerstones of the analysis between energy transition and eco-welfare.
Ecological and Evolutionary Physiology, volume 97 number 1 (January/February 2024)
by Ecological and Evolutionary PhysiologyThis is volume 97 issue 1 of Ecological and Evolutionary Physiology. Ecological and Evolutionary Physiology primarily publishes original research in physiological ecology, ecophysiology, comparative physiology, and evolutionary physiology. Studies at all levels of biological organization from the molecular to the whole organism are welcome, and work that integrates across levels of organization is particularly encouraged. Studies that focus on behavior or morphology are welcome, so long as they include ties to physiology or biochemistry, in addition to having an ecological or evolutionary context. Subdisciplines of interest include nutrition and digestion, salt and water balance, epithelial and membrane transport, gas exchange and transport, acid-base balance, temperature adaptation, energetics, structure and function of macromolecules, chemical coordination and signal transduction, nitrogen metabolism and excretion, locomotion and muscle function, biomechanics, circulation, behavioral, comparative and mechanistic endocrinology, sensory physiology, neural coordination, and ecotoxicology ecoimmunology.