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Das Retinale Pigmentepithel – Physiologie und Pathologie

by Alexa Karina Klettner Stefan Dithmar

Dieses Buch bietet eine aktuelle Quelle zu einem der Hauptakteure bei Netzhauterkrankungen - dem Retinalen Pigmentepithel (RPE). Im gesamten Buch werden die physiologische und die pathologische Funktion des RPE gleichberechtigt behandelt, um dem Leser zu helfen, das RPE als Ganzes zu verstehen. Darüber hinaus werden die Entwicklung des RPE in Diagnostik und Therapie sowie einige praktische Erkenntnisse über experimentelle RPE-Modelle behandelt. Retinal Pigment Epithelium in Health and Disease hebt neue Erkenntnisse der RPE-Forschung hervor und enthält den aktuellen Wissensstand zu jedem vorgestellten RPE-Thema. Dieses wichtige Merkmal hebt dieses Buch von anderen Publikationen ab, da die Kapitel nach einem Schema aufgebaut sind, das vom Allgemeinen zum Speziellen führt, um eine präzise Sammlung der bekannten Fakten zu bieten. Die Kapitel sind von namhaften Experten verfasst, die derzeit als Berater, Grundlagenwissenschaftler und Gruppenleiter auf dem Gebiet tätig sind undso eine fachkundige Anleitung zu den aktuellen Aspekten und Zukunftsaussichten dieses Themas bieten.

Das Recht der Fiktion: Zu den Lizenzen und juristischen Implikationen fiktionalen Schreibens (Theorema. Literaturtheorie, Methodologie, Ästhetik #3)

by Nursan Celik

Verrechtlichungsprozesse von Literatur stellen als Kollisionsfall von Kunstfreiheit und allgemeinem Persönlichkeitsrecht nicht nur für die Jurisprudenz eine Herausforderung dar. Auch die Fiktionstheorie findet im besonderen Redestatus und den Fiktionslizenzen der Literatur ein reiches Feld. Die vorliegende Studie widmet sich systematisch anhand tatsächlich verhandelter Fälle und mit Blick auf neuere Fiktionsansätze der Frage, ob fiktionalen Texten Persönlichkeitsrechtsverletzungen angelastet werden können. Hierfür wird ausgehend von der Referenzstruktur fiktionaler Literatur untersucht, in welchen Fällen sich Elemente in der Darstellung literarischer Figuren auf reale Personen beziehen lassen und infolgedessen justiziabel werden können.

Das dynamische Vertriebsmindset: Mit einer positiven inneren Haltung den Unternehmenserfolg sichern

by Philipp Metzger

Dieses Buch erläutert, warum die innere Haltung von Mitarbeitenden ein entscheidender Erfolgsfaktor ist und wie Vertriebsorganisationen diese gezielt fördern können. Konkret geht es um das dynamische Mindset, welches wesentlich zum Erfolg beiträgt, vor allem in Change-Phasen, die etwa im Rahmen von Digitalisierungsbestrebungen in Unternehmen stattfinden. Individuelle Emotionen und Motivationen, Prozesse und Kennzahlen müssen dann zusammengeführt werden.Der Autor zeigt die psychologischen Hintergründe zur Macht von Gedanken auf, und erklärt, wie ein dynamisches Mindset bei Menschen entsteht, welche unterschiedlichen Ausprägungen es gibt und welche Möglichkeiten zu einer positiven Veränderung bestehen. Er erläutert, wie ein Mindset zu jedem Zeitpunkt im Leben durch aktives Steuern beeinflusst werden kann und wie Vertriebsmitarbeiter und Führungskräfte hierbei gezielt vorgehen können – um Strahlkraft ins gesamte Unternehmen zu gewinnen und dieses nachhaltig erfolgreicher zu machen.

Darragh: My Story

by Darragh Ó Sé

For 16 years, Darragh Ó Sé wore the number 8 jersey for Gaelic football's most celebrated county, stoking the fires in Kerry's engine room. With six All Ireland medals, he is the most decorated footballer of the modern era.Darragh's name is synonymous with his county's unrelenting appetite for success, but throughout his illustrious career he has held his counsel, allowing his football to do the talking. Until now.This is the story of a modern Kerry icon. Uncompromising, passionate and possessing a savage wit, Darragh talks openly for the first time about his life in the green and gold, and about his constant drive to succeed.Elsewhere in the book, he details his setbacks, reflects on a family tragedy and reveals how his upbringing on the fringe of west Kerry helped shape his character, steeling him for a career in the toughest position in Gaelic football. This is the story of Darragh Ó Sé - the life of a legend.

Darling Jim: A Novel

by Christian Moerk

A modern gothic novel of suspense that reveals, through their diaries, the story of sisters who fall in love with a beguiling stranger, and of the town that turns a blind eye to his murderous waysWhen two sisters and their aunt are found dead in their suburban Dublin home, it seems that the secret behind their untimely demise will never be known. But then Niall, a young mailman, finds a mysterious diary in the post office's dead-letter bin. From beyond the grave, Fiona Walsh shares the most tragic love story he's ever heard—and her tale has only just begun. Niall soon becomes enveloped by the mystery surrounding itinerant storyteller Jim, who traveled through Ireland enrapturing audiences and wooing women with his macabre mythic narratives. Captivated by Jim, townspeople across Ireland thought it must be a sad coincidence that horrific murders trailed him wherever he went—and they failed to connect that the young female victims, who were smitten by the newest bad boy in town, bore an all too frightening similarity to the victims in Jim's own fictional plots. The Walsh sisters, fiercely loyal to one another, were not immune to "darling" Jim's powers of seduction, but found themselves in harm's way when they began to uncover his treacherous past. Niall must now continue his dangerous hunt for the truth—and for the vanished third sister—while there's still time. And in the woods, the wolves from Jim's stories begin to gather.

Darling Girls: A Novel

by Sally Hepworth

SISTERS, SECRETS, LOVE, AND MURDER... Sally Hepworth’s new novel has it all.For as long as they can remember, Jessica, Norah, and Alicia have been told how lucky they are. As young girls they were rescued from family tragedies and raised by a loving foster mother, Miss Fairchild, on an idyllic farming estate and given an elusive second chance at a happy family life. But their childhood wasn’t the fairy tale everyone thinks it was. Miss Fairchild had rules. Miss Fairchild could be unpredictable. And Miss Fairchild was never, ever to be crossed. In a moment of desperation, the three broke away from Miss Fairchild and thought they were free. Even though they never saw her again, she was always somewhere in the shadows of their minds. When a body is discovered under the home they grew up in, the foster sisters find themselves thrust into the spotlight as key witnesses. Or are they prime suspects?A thrilling page-turner of sisterhood, secrets, love, and murder by New York Times bestselling author Sally Hepworth.“Sally Hepworth writes characters you love.” —LIANE MORIARTY, BESTSELLING AUTHOR OF APPLES NEVER FALL

Darline Dominant

by Tania d'Alanis

When Darline Pomeroy engages the submisive young Patrick to be her boy-maid, he is made to serve her in many humiliating ways. He must wear women's clothes, paint Darline's nails and perform the most demeaning household chores; if he errs in the slightest he is whipped or caned.Darline shows off her new boy-maid to a number of her dominatrix freinds, who take great pleasure in teaching him the rules of good and ladylike comportment. But can Patrick ever hope to meet the exacting standards of these cruel mistresses?

The Darkness Rises

by Stacy Stokes

A gripping speculative thriller perfect for fans of Lauren Oliver and Ginny Myers Sain, about one girl with the power to see death before it happens—and the terrible consequences she faces when saving someone goes wrong.SOMEONE WANTS REVENGE…Whitney knows what death looks like. Since she was seven, she&’s seen it hover over strangers&’ heads in dark, rippling clouds. Sometimes she can save people from the darkness. Sometimes she can&’t. But she&’s never questioned if she should try. Until the unthinkable happens—and a person she saves becomes the perpetrator of a horrific school shooting.Now Whitney will do anything to escape the memory of last year&’s tragedy and the guilt that gnaws at her for her role in it. Even if that means quitting dance—the thing she loves most—and hiding her ability from her family and friends. But most importantly, no one can know what really happened last year.Then Whitney finds an ominous message in her locker and realizes someone knows her secret. As the threats pile up, one thing becomes clear—someone wants payback for what she did. And if she&’s going to survive the year, she must track down whoever is after her before it&’s too late.

The Darkness and the Thunder: 1915: The Great War Series (The Great War #2)

by Stewart Binns

The second in Stewart Binns' acclaimed Great War Series, The Darkness and the Thunder is a sweeping story of war following five families through the terrifying conditions of the Western Front, the slaughter of Gallipoli and the heartbreak of those left at home. 'The book on the conflict remembered 100 years on' Jon Wise, Sunday Sport-1915- The Western Front is a wasteland of barbed wire, shell craters and mud-filled trenches. Winston Churchill, searching for a solution to the stalemate, commits the Allies to a disastrous Gallipoli campaign. As men on both sides die in droves, miners and mill-workers work tirelessly for the war effort while families confront the broken bodies of returning soldiers. Nurses, soldiers, politicians, factory-workers and children - all are torn apart by war, and for husbands and sons, mothers and wives, the old way of life is vanishing.*** Praise for Stewart Binns:'Anyone with even a vague interest in Britain and the Great War should read The Shadow of War' Celia Sandys, granddaughter of Winston Churchill 'Stewart Binns has produced a real page-turner, a truly stunning adventure story' Alastair Campbell 'A fascinating mix of fact, legend and fiction . . . this is storytelling at its best' Daily Mail 'Unique, entertaining and eye-opening' Robin Carter, Parmenion Books 'A tour de force of writing brilliance' Books Monthly 'Unarguably heart-warming... will leave any reader with a sense of British pride' Goodreads 'Truly a book that educates while entertaining, a talent of this best-selling author' Historical Novel Review

Darkmans: A Novel

by Nicola Barker

“Hilarious and erudite, spooky and unconventional, Darkmans is a dazzling achievement.” — Washington PostShortlisted for the Man Booker Prize, Darkmans is an exhilarating, extraordinary examination of the ways in which history can play jokes on us all... If History is just a sick joke which keeps on repeating itself, then who exactly might be telling it, and why? Could it be John Scogin, Edward IV's infamous court jester, whose favorite pastime was to burn people alive—for a laugh? Or could it be Andrew Boarde, Henry VIII's physician, who kindly wrote John Scogin's biography? Or could it be a tiny Kurd called Gaffar whose days are blighted by an unspeakable terror of–uh–salad? Or a beautiful, bulimic harpy with ridiculously weak bones? Or a man who guards Beckley Woods with a Samurai sword and a pregnant terrier?Darkmans is a very modern book, set in Ashford [a ridiculously modern town], about two very old-fashioned subjects: love and jealousy. It's also a book about invasion, obsession, displacement and possession, about comedy, art, prescription drugs and chiropody. And the main character? The past, which creeps up on the present and whispers something quite dark—quite unspeakable—into its ear.The third of Nicola Barker's narratives of the Thames Gateway, Darkmans is an epic novel of startling originality.

Darkling

by K M Peyton

Darkling is ragged and wild, but Jenny can't help falling for him. As soon as her grandfather buys the chestnut colt, she is thrilled. But a racing colt turns out to be a frightening responsibility - especially one as temperamental as Darkling . . .

Darkest Truth: She refused to be silenced (Finn Fitzpatrick Series #1)

by Catherine Kirwan

Recommended by Graham Norton on The Graham Norton Show_________________________He'll do anything to protect his secrets. She'll stop at nothing to expose the truth.It only takes one person to break the silence.When solicitor Finn Fitzpatrick is approached by a man to investigate the death of his daughter, her first instinct is to refuse. The father is grieving, and unable to accept that his daughter committed suicide. And yet something about the man’s story chimes with Finn. Why did a bright, confident, beautiful young girl suddenly drop out of school? Could the answer lie in her relationship with Ireland's most famous film director?The deeper Finn goes into the case, the more dark, twisted and dangerous the picture becomes.Because these are powerful people she is trying to expose. And they're willing to do anything to keep the truth hidden._________________________'Just finished Darkest Truth by Catherine Kirwan. It's brilliant! A heroine flawed but not in the normal whisky-soaked-my-wife-has-left me way - that takes you on an evocative crime journey through the cut-throughs and cobbles of Cork City. A fabulous sleep thief and great read.' OWEN McDONNELL, Killing Eve'A clever twist on the genre.' ARAMINTA HALL, author of Our Kind of Cruelty'A gripping, twisting novel of mounting suspense. It couldn't be more relevant.' AMY LLOYD, author of The Innocent Wife'A fast-paced and twisty thriller, with a gutsy protagonist you can't help but root for. It left me breathless.' CLAIRE ASKEW, author of All The Hidden Truths'The story is told at a propulsive rate, the legal details are persuasive and the dialogue is excellent.' IRISH TIMES'This is a wonderfully assured debut. While the plot of Darkest Truth may have been suggested by the recent worldwide #MeToo movement, there is little of the 'me too' in its writing because Kirwan delivers her cracking tale in her own distinctive voice. In Finn Fitzpatrick, she has created an immensely likeable, feisty and individual character, and the supporting cast in this intriguing mystery are equally well drawn.' IRISH INDEPENDENT'Her quest to expose Gill is dark and twisted, but the believability of the characters is undeniable. Powerful writing’ WOMAN

The Darkest Night: a twisty historical mystery to keep you reading through the night

by Victoria Hawthorne

Some secrets last for generations . . . 'Deliciously twisty' HEATHER DARWENT'Full of mystery' ANITA FRANK'A wonderfully twisting tale of family secrets' REBECCA NETLEYA bewitching and haunting story of family secrets - and the lengths some will go to protect them.When Ailsa Reid's life in London begins to fall apart, she escapes to her grandparents' house in Fife. But she arrives to find her grandmother, Moira - recently diagnosed with dementia - has gone missing.Desperate to ensure Moira's safe return, Ailsa must rely on the help of her estranged mother, Rowan. Tensions simmer between the two women as they attempt to piece together what has happened.To find Moira, both Ailsa and Rowan must look to their ancestors, to a story about witches burned on the hill above the Reid house centuries ago and the curse laid upon the women that came after. Can they break the bonds of history in time to save their family? Or will the Reid curse be their undoing?Perfect for fans of C. J. Cooke and Rebecca Netley.

The Darkest Night: a twisty historical mystery to keep you reading through the night

by Victoria Hawthorne

Some secrets last for generations . . . 'Deliciously twisty' HEATHER DARWENT'Full of mystery' ANITA FRANK'A wonderfully twisting tale of family secrets' REBECCA NETLEYA bewitching and haunting story of family secrets - and the lengths some will go to protect them.When Ailsa Reid's life in London begins to fall apart, she escapes to her grandparents' house in Fife. But she arrives to find her grandmother, Moira - recently diagnosed with dementia - has gone missing.Desperate to ensure Moira's safe return, Ailsa must rely on the help of her estranged mother, Rowan. Tensions simmer between the two women as they attempt to piece together what has happened.To find Moira, both Ailsa and Rowan must look to their ancestors, to a story about witches burned on the hill above the Reid house centuries ago and the curse laid upon the women that came after. Can they break the bonds of history in time to save their family? Or will the Reid curse be their undoing?Perfect for fans of C. J. Cooke and Rebecca Netley.

The Darkest Night

by Victoria Hawthorne

Some secrets last for generations . . .A bewitching and haunting story of family secrets - and the lengths some will go to protect them.When Ailsa Reid becomes the subject of a trial by media after an incident at the school where she works, she escapes to the comfort of her grandparents' house in Fife. But she arrives to find her grandmother, Moira - recently diagnosed with dementia - has gone missing, and her grandfather, Rupert, gravely injured.Desperate to ensure Moira's safe return, Ailsa must rely on the help of her estranged mother, Rowan, who abandoned her at birth. Tensions simmer between the two women as they attempt to piece together the lead-up to Moira's disappearance.But to move forward and find Moira, both Ailsa and Rowan must look to their ancestors, and to a story about witches burned on the hill above the Reid house centuries ago. Can they break the bonds of history in time to save their family? Or will the Reid curse be their undoing?(P) 2023 Quercus Editions Limited

Darkest Longings

by Susan Lewis

Claudine Rafferty is rich, reckless and beautiful. So when she throws herself into an arranged marriage with the eminently eligible but notorious François de Lorvoire, everyone in Paris is amazed. Determined to cope with François's cruelty and indifference, Claudine soon finds herself driven to find love in the arms of Armand St Jacques, one of her husband's vignerons.But all is not what it seems in the de Lorvoire family. As Claudine learns more of Francois's sinister past, she also inherits some of his most dangerous enemies. And against a background of betrayal and conspiracy, she forced to learn not only whom she can trust, but also whom she really loves...

Darkest Before Dawn: The compelling and spellbinding historical fiction novel from the Sunday Times bestselling author

by Katie Flynn

The Todd family are strangers to city life when they move into a flat on the Scotland Road; their previous home was a canal barge. Harry gets a job as warehouse manager and his wife, Martha, works in a grocer's shop, whilst Seraphina trains as a teacher, Angela works in Bunney's Department Store and young Evie starts at regular school.Then circumstances change and Seraphina takes a job as a nippy in Lyon's Corner House. Customers vie for her favours, including an old friend, Toby.When war is declared the older girls join up, leaving Evie and Martha to cope with rationing, shortages, and the terrible raids on Liverpool which devastate the city. Meanwhile, Toby is a Japanese POW, working on the infamous Burma railway and dreaming of Seraphina...Darkest Before Dawn is a warm passionate story that makes it easy to see why Katie Flynn is one of Britain's most popular saga writers.

Darker Than Desire: A Secrets And Shadows Novel (The Secrets & Shadows Novels #3)

by Shiloh Walker

LUST FOR LIFENo matter how many times he's left her in the past, Sybil Chalmers can't ignore her feelings for the one man who stole her heart years ago. For countless nights, she has waited for him--for his kiss, his touch-and has longed for him to emerge from the shadows of his past. Only when she is in his arms does Sybil really feel alive...and finally, after all these years, that time is now.A DEADLY DESIREHe's a man raised in a world of strict rules and unbreakable traditions and he's always yearned to break free. But when a family tragedy lures him back home, he finds his one true passion has been there all along. With Sybil, he can explore his greatest potential-and allow her to discover a whole new level of ecstasy. But will a long-buried secret threaten to tear them apart? The only thing he knows for sure is that he will do anything to keep Sybil in his life...and keep her coming back for more...in Darker Than Desire by Shiloh Walker."Shiloh Walker's writing just gets better and better...[and] the sex is sizzling." -RT Book Reviews

Dark Vision

by Debbie Johnson

Lily McCain is cursed.With just one touch she can see a person’s future, whether it’s a good fortune or a terrible fate. Afraid of the potent visions she foresees, she distances herself from the world, succumbing to a life of solitude.But at the touch of a mysterious stranger – who has powers of his own – Lily sees a new, chilling future for herself: one where she is fated to make a terrible choice...A Daily Express magazine 'Must Read!'Debbie Johnson is also winner of the Best Short Romance for Pippa's Cornish Dream at the Love Stories Awards 2015.

Dark Towers: Deutsche Bank, Donald Trump, and an Epic Trail of Destruction

by David Enrich

#1 WALL STREET JOURNAL BESTSELLER * NEW YORK TIMES BESTSELLER New York Times finance editor David Enrich's explosive exposé of the most scandalous bank in the world, revealing its shadowy ties to Donald Trump, Putin's Russia, and Nazi Germany“A jaw-dropping financial thriller” —Philadelphia InquirerOn a rainy Sunday in 2014, a senior executive at Deutsche Bank was found hanging in his London apartment. Bill Broeksmit had helped build the 150-year-old financial institution into a global colossus, and his sudden death was a mystery, made more so by the bank’s efforts to deter investigation. Broeksmit, it turned out, was a man who knew too much.In Dark Towers, award-winning journalist David Enrich reveals the truth about Deutsche Bank and its epic path of devastation. Tracing the bank’s history back to its propping up of a default-prone American developer in the 1880s, helping the Nazis build Auschwitz, and wooing Eastern Bloc authoritarians, he shows how in the 1990s, via a succession of hard-charging executives, Deutsche made a fateful decision to pursue Wall Street riches, often at the expense of ethics and the law.Soon, the bank was manipulating markets, violating international sanctions to aid terrorist regimes, scamming investors, defrauding regulators, and laundering money for Russian oligarchs. Ever desperate for an American foothold, Deutsche also started doing business with a self-promoting real estate magnate nearly every other bank in the world deemed too dangerous to touch: Donald Trump. Over the next twenty years, Deutsche executives loaned billions to Trump, the Kushner family, and an array of scandal-tarred clients, including convicted sex offender Jeffrey Epstein. Dark Towers is the never-before-told saga of how Deutsche Bank became the global face of financial recklessness and criminality—the corporate equivalent of a weapon of mass destruction. It is also the story of a man who was consumed by fear of what he’d seen at the bank—and his son’s obsessive search for the secrets he kept.

Dark Touch: The Hunt (Dark Touch #2)

by Amy Meredith

Something is hunting. Something that will kill to get what it wants. And it isn't human. Eve knows that her supernatural powers are called for, but she'd rather focus on dating than demons and gorgeous Luke is, frankly, pretty distracting. He's already a friend - but could he be something more? Do Luke and Eve really have a future? And with demons on the hunt, will either of them live long enough to find out?

Dark Touch: Betrayal (Dark Touch #4)

by Amy Meredith

A hot new boyfriend. Prom just round the corner. And not a demon in sight . . .Things have never been better for Eve Evergold, Deepdene's kick-ass witch.But when things seem too good to be true, they usually are. An evil far greater than Eve has ever known is at work in Deepdene - and it's hell-bent on turning her closest friends against her. This time, it looks like Eve is going to have to face her demons alone . . .

Dark Touch

by Debbie Johnson

It’s not easy finding out you’re a Goddess. For Lily McCain, the move from local music journalist to being the incarnation of Mabe, Mother of Mortals was a surprise to say the least.Thrust into a game of gods and monsters, the rules of which she barely knows, one thing is clear: if you have power, someone will try to take it from you.A Daily Express magazine 'Must Read!'Debbie Johnson is also winner of the Best Short Romance for Pippa's Cornish Dream at the Love Stories Awards 2015.

Dark Tempest (Red Winter Trilogy Ser. #Vol. 2)

by Annette Marie

Emi has dedicated her life to becoming the perfect vessel for the goddess Amaterasu, but the insidious betrayal of another deity has changed everything. Now Amaterasu has charged Emi with an urgent mission: to find and free the earthly gods before mankind is brought to its knees beneath divine tyranny. At her side is Shiro, the mysterious fox spirit. When she first saved his life, she could never have imagined that behind his cunning and confidence, he was lost--his power bound by a devastating curse and his memories obscured. His veiled history is somehow tied to the missing gods, but he can't remember how or why. As their search leads them into the murky depths of the spirit realm, the shadows of Shiro's past begin to emerge. With each brief awakening of his true self, she loses a little more of him. The fate of the heavens and earth rest in her mortal hands, and she must find the missing gods before time runs out for her world--and for Shiro. Dark Tempest includes 10 full-page illustrations by award-winning artist Brittany Jackson.

Dark Sundays: Dark Sundays (CSI: Crime Scene Investigation)

by Donn Cortez

A lavish penthouse party on top of a Vegas hotel and casino plays host to a bizarre set-up to murder in which a security guard is trapped and killed in a private elevator—and the body soon vanishes . . . leading crime scene investigators Nick Stokes and Greg Sanders straight to an uncanny circus troupe with deadly connections to none other than the Russian mafia. In the meantime, Ray Langston and Catherine Willows are called to a psychiatric facility where two patients have just escaped after attacking an orderly. One of the escaped patients, an Iraq war veteran, managed to smuggle in a military-grade nerve gas, inducing realistic and shared three-dimensional illusions and hallucinations . . . and Ray and Catherine must race against time in order to find two very dangerous individuals now roaming freely on the streets of Las Vegas. . . .

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