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Learn how to configure, implement, enhance, and customize SAP OEE to address manufacturing performance management. Manufacturing Performance Management using SAP OEE will show you how to connect your business processes with your plant systems and how to integrate SAP OEE with ERP through standard workflows and shop floor systems for automated data collection. Manufacturing Performance Management using SAP OEE is a must-have comprehensive guide to implementing SAP OEE. It will ensure that SAP consultants and users understand how SAP OEE can offer solutions for manufacturing performance management in process industries. With this book in hand, managing shop floor execution effectively will become easier than ever. Authors Dipankar Saha and Mahalakshmi Symsunder, both SAP manufacturing solution experts, and Sumanta Chakraborty, product owner of SAP OEE, will explain execution and processing related concepts, manual and automatic data collection through the OEE Worker UI, and how to enhance and customize interfaces and dashboards for your specific purposes. You'll learn how to capture and categorize production and loss data and use it effectively for root-cause analysis. In addition, this book will show you: Various down-time handling scenarios. How to monitor, calculate, and define standard as well as industry-specific KPIs. How to carry out standard operational analytics for continuous improvement on the shop floor, at local plant level using MII and SAP Lumira, and also global consolidated analytics at corporation level using SAP HANA. Steps to benchmark manufacturing performance to compare similar manufacturing plants' performance, leading to a more efficient and effective shop floor. Manufacturing Performance Management using SAP OEE will provide you with in-depth coverage of SAP OEE and how to effectively leverage its features. This will allow you to efficiently manage the manufacturing process and to enhance the shop floor's overall performance, making you the sought-after SAP OEE expert in the organization. What You Will Learn Configure your ERP OEE add-on to build your plant and global hierarchy and relevant master data and KPIs Use the SAP OEE standard integration (SAP OEEINT) to integrate your ECC and OEE system to establish bi-directional integration between the enterprise and the shop floor Enable your shop floor operator on the OEE Worker UI to handle shop floor production execution Use SAP OEE as a tool for measuring manufacturing performance Enhance and customize SAP OEE to suit your specific requirements Create local plant-based reporting using SAP Lumira and MII Use standard SAP OEE HANA analytics Who This Book Is For SAP MII, ME, and OEE consultants and users who will implement and use the solution.
Unleash your visual learner's potential with this practical guide. Learn proven, easy to apply strategies for the specific way your child learns and processes information. This guide is packed with over 14 years of hands-on experience, examples, charts, and guides. By adopting the strategies presented, you'll enjoy watching your child blossom into a confident, successful and independent student because learning makes sense.
Beginning Ubuntu for Windows and Mac Users is your comprehensive guide to using Ubuntu. You already know how to use a computer running Windows or OS X, but learning a new operating system can feel daunting. If you've been afraid to try Ubuntu because you don't know where to start, this book will show you how to get the most out of Ubuntu for work, home, and play. You'll be introduced to a wide selection of software and settings that will make your computer ready to work for you. Ubuntu makes your computing life easy. Ubuntu's Software Updater keeps all of your software secure and up-to-date. Browsing the Internet becomes faster and safer. Creating documents and sharing with others is built right in. Enjoying your music and movie libraries helps you unwind. In addition to a tour of Ubuntu's modern and easy-to-use interface, you'll also learn how to: * Understand the advantages of Ubuntu and its variants--Kubuntu, Xubuntu, and more * Install Ubuntu on its own or alongside your computer's existing operating system * Search Ubuntu's catalog of thousands of applications--all ready to install with a single click * Work with files and disks that were created with Windows and OS X * Run simple, interesting tasks and games using the command line * Customize Ubuntu in powerful ways and get work done with virtual machines Ubuntu is the world's third most popular operating system and powers desktop and laptop computers, servers, private and public clouds, phones and tablets, and embedded devices. There's never been a better time to install Ubuntu and move to an open source way of life. Get started with Beginning Ubuntu for Windows and Mac Users today!
Numerical Python by Robert Johansson shows you how to leverage the numerical and mathematical modules in Python and its Standard Library as well as popular open source numerical Python packages like NumPy, FiPy, matplotlib and more to numerically compute solutions and mathematically model applications in a number of areas like big data, cloud computing, financial engineering, business management and more. After reading and using this book, you'll get some takeaway case study examples of applications that can be found in areas like business management, big data/cloud computing, financial engineering (i. e. , options trading investment alternatives), and even games. Up until very recently, Python was mostly regarded as just a web scripting language. Well, computational scientists and engineers have recently discovered the flexibility and power of Python to do more. Big data analytics and cloud computing programmers are seeing Python's immense use. Financial engineers are also now employing Python in their work. Python seems to be evolving as a language that can even rival C++, Fortran, and Pascal/Delphi for numerical and mathematical computations.
Many corporations are finding that the size of their data sets are outgrowing the capability of their systems to store and process them. The data is becoming too big to manage and use with traditional tools. The solution: implementing a big data system. As Big Data Made Easy: A Working Guide to the Complete Hadoop Toolset shows, Apache Hadoop offers a scalable, fault-tolerant system for storing and processing data in parallel. It has a very rich toolset that allows for storage (Hadoop), configuration (YARN and ZooKeeper), collection (Nutch and Solr), processing (Storm, Pig, and Map Reduce), scheduling (Oozie), moving (Sqoop and Avro), monitoring (Chukwa, Ambari, and Hue), testing (Big Top), and analysis (Hive). The problem is that the Internet offers IT pros wading into big data many versions of the truth and some outright falsehoods born of ignorance. What is needed is a book just like this one: a wide-ranging but easily understood set of instructions to explain where to get Hadoop tools, what they can do, how to install them, how to configure them, how to integrate them, and how to use them successfully. And you need an expert who has worked in this area for a decade--someone just like author and big data expert Mike Frampton. Big Data Made Easy approaches the problem of managing massive data sets from a systems perspective, and it explains the roles for each project (like architect and tester, for example) and shows how the Hadoop toolset can be used at each system stage. It explains, in an easily understood manner and through numerous examples, how to use each tool. The book also explains the sliding scale of tools available depending upon data size and when and how to use them. Big Data Made Easy shows developers and architects, as well as testers and project managers, how to: Store big dataConfigure big dataProcess big dataSchedule processesMove data among SQL and NoSQL systemsMonitor dataPerform big data analytics Report on big data processes and projectsTest big data systemsBig Data Made Easy also explains the best part, which is that this toolset is free. Anyone can download it and--with the help of this book--start to use it within a day. With the skills this book will teach you under your belt, you will add value to your company or client immediately, not to mention your career.
Biopharmaceutical medicines, the newest class of therapeutics, are quite heterogeneous and include a range of molecules such as proteins, peptides, vaccines and nucleic acids, with use in virtually all therapeutic fields (e. g. cancer and infectious diseases, vaccination, metabolic dysfunctions) and diagnostics. This edited book gives a concise and up-to-date overview of the biological features justifying the use of different human mucosa as delivery routes for biopharmaceuticals, the technological strategies that have been followed so far regarding the optimization of mucosal potentialities as well as the challenges that arise with the advent of new biopharmaceutical drugs and alternative means of administration. Following a brief introduction, the first section addresses general aspects of the biology of mucosal tissues and their unique aspects toward beneficial or deleterious interaction with biopharmaceuticals and their delivery systems. The second part reviews the different delivery strategies that have recently been investigated for different mucosal sites. The third section describes the development and clinical applications of drug delivery systems and products enclosing biopharmaceuticals for mucosal delivery, with a focus on the most successful case studies of recent years. The last section briefly centers on relevant aspects of the regulatory, toxicological and market issues of mucosal delivery of biopharmaceuticals. Scientists and researchers in the fields of drug delivery, material science, biomedical science and bioengineering as well as professionals, regulators and policy makers in the pharmaceutical, biotechnology and healthcare industries will find in this book an important compendium of fundamental concepts and practical tools for their daily research and activities.
This addition to the ISOR series addresses the analytics of the operations of electric energy systems with increasing penetration of stochastic renewable production facilities, such as wind- and solar-based generation units. As stochastic renewable production units become ubiquitous throughout electric energy systems, an increasing level of flexible backup provided by non-stochastic units and other system agents is needed if supply security and quality are to be maintained. Within the context above, this book provides up-to-date analytical tools to address challenging operational problems such as: * The modeling and forecasting of stochastic renewable power production. * The characterization of the impact of renewable production on market outcomes. * The clearing of electricity markets with high penetration of stochastic renewable units. * The development of mechanisms to counteract the variability and unpredictability of stochastic renewable units so that supply security is not at risk. * The trading of the electric energy produced by stochastic renewable producers. * The association of a number of electricity production facilities, stochastic and others, to increase their competitive edge in the electricity market. * The development of procedures to enable demand response and to facilitate the integration of stochastic renewable units. This book is written in a modular and tutorial manner and includes many illustrative examples to facilitate its comprehension. It is intended for advanced undergraduate and graduate students in the fields of electric energy systems, applied mathematics and economics. Practitioners in the electric energy sector will benefit as well from the concepts and techniques explained in this book.
Nanoscience or the science of the very small offers the pharmaceutical scientist a wealth of opportunities. By fabricating at the nanoscale, it is possible to exert unprecedented control on drug activity. This textbook will showcase a variety of nanosystems working from their design and construction to their application in the field of drug delivery. The book is intended for graduate students in drug delivery, physical and polymer chemistry, and applied pharmaceutical sciences courses that involve fundamental nanoscience. The purpose of the text is to present physicochemical and biomedical properties of synthetic polymers with an emphasis on their application in polymer therapeutics i. e. , pharmaceutical nanosystems, drug delivery and biological performance. There are two main objectives of this text. The first is to provide advanced graduate students with knowledge of the principles of nanosystems and polymer science including synthesis, structure, and characterization of solution and solid state properties. The second is to describe the fundamentals of therapeutic applications of polymers in drug delivery, targeting, response modifiers as well as regulatory issues. The courses, often listed as Advanced Drug Delivery and Applied Pharmaceutics; Polymer Therapeutics; or Nanomedicine, are designed as an overview of the field specifically for graduate students in the Department of Pharmaceutical Sciences Graduate Programs. However, the course content may also be of interest for graduate students in related biomedical research programs. These courses generally include a discussion of the major principles of polymer science and fundamental concepts of application of polymers as modern therapeutics. All courses are moving away from the above mentioned course names and going by 'pharmaceutical nanoscience or nanosystems'. This area of research and technology development has attracted tremendous attention during the last two decades and it is expected that it will continue to grow in importance. However, the area is just emerging and courses are limited but they are offered.
From the Preface: This festschrift is devoted to recognize the career of a man who not only witnessed the growth of operations research from its inception, but also contributed significantly to this growth. Dr. Salah E. Elmaghraby received his doctorate degree from Cornell University in 1958, and since then, his scholarly contributions have enriched the fields of production planning and scheduling and project scheduling. This collection of papers is contributed in his honor by his students, colleagues, and acquaintances. It offers a tribute to the inspiration received from his work, and from his guidance and advice over the years, and recognizes the legacy of his many contributions. Dr. Elmaghraby is a pioneer in the area of project scheduling (in particular, project planning and control through network models, for which he coined the term 'activity networks'. ) In his initial work in this area, he developed an algebra based on signal flow graphs and semi-Markov processes for analyzing generalized activity networks involving activities with probabilistic durations. This work led to the development of what was later known as the Graphical Evaluation and Review Technique (GERT), and GERT simulation models. He has made fundamental contributions in determining criticality indices for activities, in developing methodologies for project compression and time/cost analysis, and in the use of stochastic and chance-constrained programming and Petri Nets for the analysis of activity networks. This volume brings together fourteen contributions, which can be viewed under the following three main themes: operations research and its application in production planning; project scheduling, and production scheduling, inspired by, and in many cases based on, Dr. Elmaghraby's work in these areas. The first five chapters are devoted to the first theme, followed by four chapters each devoted to the other two, respectively. An additional chapter is devoted to the vulnerability of multimodal freight systems.
Waves in Neural Media: From Single Neurons to Neural Fields surveys mathematical models of traveling waves in the brain, ranging from intracellular waves in single neurons to waves of activity in large-scale brain networks. The work provides a pedagogical account of analytical methods for finding traveling wave solutions of the variety of nonlinear differential equations that arise in such models. These include regular and singular perturbation methods, weakly nonlinear analysis, Evans functions and wave stability, homogenization theory and averaging, and stochastic processes. Also covered in the text are exact methods of solution where applicable. Historically speaking, the propagation of action potentials has inspired new mathematics, particularly with regard to the PDE theory of waves in excitable media. More recently, continuum neural field models of large-scale brain networks have generated a new set of interesting mathematical questions with regard to the solution of nonlocal integro-differential equations. Advanced graduates, postdoctoral researchers and faculty working in mathematical biology, theoretical neuroscience, or applied nonlinear dynamics will find this book to be a valuable resource. The main prerequisites are an introductory graduate course on ordinary differential equations or partial differential equations, making this an accessible and unique contribution to the field of mathematical biology.
The Essentials in Cytopathology book series fulfills the need for an easy-to-use and authoritative synopsis of site specific topics in cytopathology. These guide books fit into the lab coat pocket and are ideal for portability and quick reference. Each volume is heavily illustrated with a full color art program, while the text follows a user-friendly outline format. Central Nervous System Intraoperative Cytopathology covers the full spectrum of benign and malignant conditions of the CNS with emphasis on common disorders. The volume is heavily illustrated and contains useful algorithms that guide the reader through the differential diagnosis of common and uncommon entities encountered in the field of intraoperative neuro-cytopathology. Central Nervous System Intraoperative Cytopathology is a valuable quick reference for pathologists, cytopathologists, and fellows and trainees dealing with this exigent field.
Deimination is a relatively new post-translational modification of proteins, whose recognition is ever-increasing. First linked to the pathology of rheumatoid arthritis (RA), deimination is a process by which selected positively charged arginine amino acids are converted to neutral citrulline amino acids by the peptidyl arginine deiminase (PAD) family of enzymes. Although the medical literature is rich with articles about the possible significance of deiminated proteins in RA, Protein Deimination in Human Health and Disease is the first publication to compile this knowledge and the growing amount of new information now known about the presence of deiminated proteins in the eye, skin, hair, gums, lung and nervous system, as well. As a result, this process has now been linked to numerous additional conditions besides RA, including cancer, glaucoma, Alzheimer's disease, Parkinson's disease, multiple sclerosis, spinal cord and peripheral nerve injury, Creutzfeldt-Jakob disease, among many others. Chronicling the earliest studies of deimination up to the present, this volume distills what is currently known about citrullination of proteins in the human body and is the first book of its kind on the topic.
Oceans were long thought to exist in all corners of the Solar System, from carbonated seas percolating beneath the clouds of Venus to features on the Moon's surface given names such as "the Bay of Rainbows" and the "Ocean of Storms." With the advent of modern telescopes and spacecraft exploration these ancient concepts of planetary seas have, for the most part, evaporated. But they have been replaced by the reality of something even more exotic. For example, although it is still uncertain whether Mars ever had actual oceans, it now seems that a web of waterways did indeed at one time spread across its surface. The "water" in many places in our Solar System is a poisoned brew mixed with ammonia or methane. Even that found on Jupiter's watery satellite Europa is believed similar to battery acid. Beyond the Galilean satellites may lie even more "alien oceans." Saturn's planet-sized moon Titan seems to be subject to methane or ethane rainfall. This creates methane pools that, in turn, become vast lakes and, perhaps, seasonal oceans. Titan has other seas in a sense, as large shifting areas of sand covering vast plains have been discovered. Mars also has these sand seas, and Venus may as well, along with oceans of frozen lava. Do super-chilled concoctions of ammonia, liquid nitrogen, and water percolate beneath the surfaces of Enceladus and Triton? For now we can only guess at the possibilities. 'Alien Seas' serves up part history, part current research, and part theory as it offers a rich buffet of "seas" on other worlds. It is organized by location and by the material of which various oceans consist, with guest authors penning specific chapters. Each chapter features new original art depicting alien seas, as well as the latest ground-based and spacecraft images. Original diagrams presents details of planetary oceans and related processes.
The refined pathophysiologal understanding of the heart failure syndrome together with the surge of new technological advances led to innovative medical and interventional treatment strategies improving the outcome of heart failure patients. However the complex interplay between the clinical presentation and the array of the interventions requires a coordinated multidisciplinary "heart team" approach involving various specialists in the cardiovascular field including clinicians, interventionalists, surgeons and cardiac intensivists. In this book, opinion leaders will review of state-of-the-art management of heart failure with particular emphasis on burning clinical questions and challenges faced by the heart team. New medical and interventional therapies for chronic and acute heart failure are addressed by bridging bench to bedside translation in science and technology into practical clinical application and guidance.
This is the most comprehensive survey of the mathematical life of the legendary Paul Erdős (1913-1996), one of the most versatile and prolific mathematicians of our time. For the first time, all the main areas of Erdős' research are covered in a single project. Because of overwhelming response from the mathematical community, the project now occupies over 1000 pages, arranged into two volumes. These volumes contain both high level research articles as well as key articles that survey some of the cornerstones of Erdős' work, each written by a leading world specialist in the field. A special chapter "Early Days", rare photographs, and art related to Erdős complement this striking collection. A unique contribution is the bibliography on Erdős' publications: the most comprehensive ever published. This new edition, dedicated to the 100th anniversary of Paul Erdős' birth, contains updates on many of the articles from the two volumes of the first edition, several new articles from prominent mathematicians, a new introduction, more biographical information about Paul Erdős, and an updated list of publications. The first volume contains the unique chapter "Early Days", which features personal memories of Paul Erdős by a number of his colleagues. The other three chapters cover number theory, random methods, and geometry. All of these chapters are essentially updated, most notably the geometry chapter that covers the recent solution of the problem on the number of distinct distances in finite planar sets, which was the most popular of Erdős' favorite geometry problems.
Forest canopies not only support high terrestrial biodiversity but also represent a critical interface between the atmosphere and the earth. They provide goods and services to support diverse human communities and offer opportunities to explore sustainable use of these resources for many generations of local livelihoods. Forest canopies are important carbon sequestration units, and in this sense, serve as climate control for the planet. Canopies are important energy production centers for the planet, and serve as the basis for many food chains. The canopy can also act as a hook for education outreach and conservation, inspiring ecotourism through recreation and other sustainable uses such as treetop walks, zip lines, and birding. Despite these critical services provided by forest canopies, almost no dedicated research in the treetops was initiated until as recently as the late 1970s when single rope techniques were developed by mountaineering professionals and adapted for use in the canopy. Subsequently, an array of canopy access tools was designed in the 1980s and early 1990s that have opened up this "eighth continent" for global exploration and discovery. This volume uses the major findings of the 5th international canopy conference as a platform for organization, but it does not mimic the sessions and presentations of the conference itself. Instead, it builds on the important themes that emerged from the conference and solicits articles that represent future priorities and advancements for canopy science in the next decade. Despite the global efforts of hundreds of forest scientists over the past 3 decades, forests are degrading at an accelerated rate and biodiversity is increasingly threatened by human activities. Given these trends - despite the very best efforts of the world's best scientists - other approaches must be taken. This volume summarizes the issue of "treetops at risk" and assembles a global authorship to examine past accomplishments and future initiatives critical in forest conservation.
Frobenius made many important contributions to mathematics in the latter part of the 19th century. Hawkins here focuses on his work in linear algebra and its relationship with the work of Burnside, Cartan, and Molien, and its extension by Schur and Brauer. He also discusses the Berlin school of mathematics and the guiding force of Weierstrass in that school, as well as the fundamental work of d'Alembert, Lagrange, and Laplace, and of Gauss, Eisenstein and Cayley that laid the groundwork for Frobenius's work in linear algebra. The book concludes with a discussion of Frobenius's contribution to the theory of stochastic matrices.
Convection in Porous Media, 4th Edition, provides a user-friendly introduction to the subject, covering a wide range of topics, such as fibrous insulation, geological strata, and catalytic reactors. The presentation is self-contained, requiring only routine mathematics and the basic elements of fluid mechanics and heat transfer. The book will be of use not only to researchers and practicing engineers as a review and reference, but also to graduate students and others entering the field. The new edition features approximately 1,750 new references and covers current research in nanofluids, cellular porous materials, strong heterogeneity, pulsating flow, and more.
This book is for students and researchers who have had a first year graduate level mathematical statistics course. It covers classical likelihood, Bayesian, and permutation inference; an introduction to basic asymptotic distribution theory; and modern topics like M-estimation, the jackknife, and the bootstrap. R code is woven throughout the text, and there are a large number of examples and problems. An important goal has been to make the topics accessible to a wide audience, with little overt reliance on measure theory. A typical semester course consists of Chapters 1-6 (likelihood-based estimation and testing, Bayesian inference, basic asymptotic results) plus selections from M-estimation and related testing and resampling methodology. Dennis Boos and Len Stefanski are professors in the Department of Statistics at North Carolina State. Their research has been eclectic, often with a robustness angle, although Stefanski is also known for research concentrated on measurement error, including a co-authored book on non-linear measurement error models. In recent years the authors have jointly worked on variable selection methods.
Beginning with the basic elements that differentiate space programs from other management challenges, Space Program Management explains through theory and example of real programs from around the world, the philosophical and technical tools needed to successfully manage large, technically complex space programs both in the government and commercial environment. Chapters address both systems and configuration management, the management of risk, estimation, measurement and control of both funding and the program schedule, and the structure of the aerospace industry worldwide.
Measuring Technology and Mechatronics Automation in Electrical Engineering includes select presentations on measuring technology and mechatronics automation related to electrical engineering, originally presented during the International Conference on Measuring Technology and Mechanatronics Automation (ICMTMA2012). This Fourth ICMTMA, held at Sanya, China, offered a prestigious, international forum for scientists, engineers, and educators to present the state of the art of measuring technology and mechatronics automation research.
The American Cancer Society recently estimated that about 45,000 new cases of thyroid cancer will be diagnosed in the United States, with three-quarters occurring in women. The overall 5-year survival rate is about 97%, making it one of the least lethal cancers. We are experiencing an epidemic of well-differentiated thyroid cancer, in part due to the widespread use of imaging modalities that detect thyroid nodules and microcarcinomas. Concurrently, there have been a number of recent advances in surgical treatment, as well as diagnostic modalities that allow us to detect small amounts of residual local and metastatic disease. Additionally, a reexamination of past treatment regimens has led to new recommendations regarding the use of radioactive iodine, and to new therapeutic options, such as targeted therapy which have supplanted the use of more toxic chemotherapy for metastatic cancer. Multiple academic organizations have developed consensus guidelines for the management of thyroid cancer, occasionally with conflicting recommendations. In Thyroid Cancer, a renowned group of authors presents a broad overview of the pathology, pathophysiology, diagnosis, and management of thyroid cancer, with an emphasis on recent evidence-based information. State-of-the-art and a significant contribution to the literature, Thyroid Cancer is an invaluable reference for endocrinologists, oncologists, nuclear medicine physicians, radiation oncologists, primary care physicians, and surgeons who deal with head and neck cancer.
Modern Management of Cancer of the Rectum is intended to provide a comprehensive overview of all aspects of rectal neoplasms. It addresses epidemiology, biology, screening and chemoprevention, the role of imaging in diagnosis, staging and prognosis, radiation therapy, medical and surgical treatment, as well as new modalities of therapy, including laparoscopy, and transanal endoscopic surgery. A greater understanding of prognostic factors, patterns of spread and natural history has occurred during the past decade; together with new diagnostic modalities this has led to significant changes in the management of patients with rectal cancer. This book will be invaluable for all those who treat rectal cancer.
This illustrated textbook is an essential and invaluable guide to young clinicians and researchers of Trauma and Orthopaedics, reporting all classification systems which are currently utilised in the clinical setting. It includes classifications relevant to both Elective Orthopaedic Practice and Orthopaedic Trauma. Clear graphic illustrations accompany the description of all different classification schemes in a comprehensive manner, together with a structured presentation of existing clinical evidence. In this manner each chapter of the different anatomical sites and pathologies assists the decision making of the readers regarding treatment strategy as well as informed consent of their patients. It is envisaged that this textbook will be a point of reference not only to the surgeons in training (residents) but also to senior surgeons and academic clinicians.
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