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Chips 2020: A Guide to the Future of Nanoelectronics (The Frontiers Collection)
by Bernd HoefflingerThe chips in present-day cell phones already contain billions of sub-100-nanometer transistors. By 2020, however, we will see systems-on-chips with trillions of 10-nanometer transistors. But this will be the end of the miniaturization, because yet smaller transistors, containing just a few control atoms, are subject to statistical fluctuations and thus no longer useful. We also need to worry about a potential energy crisis, because in less than five years from now, with current chip technology, the internet alone would consume the total global electrical power! This book presents a new, sustainable roadmap towards ultra-low-energy (femto-Joule), high-performance electronics. The focus is on the energy-efficiency of the various chip functions: sensing, processing, and communication, in a top-down spirit involving new architectures such as silicon brains, ultra-low-voltage circuits, energy harvesting, and 3D silicon technologies. Recognized world leaders from industry and from the research community share their views of this nanoelectronics future. They discuss, among other things, ubiquitous communication based on mobile companions, health and care supported by autonomous implants and by personal carebots, safe and efficient mobility assisted by co-pilots equipped with intelligent micro-electromechanical systems, and internet-based education for a billion people from kindergarden to retirement. This book should help and interest all those who will have to make decisions associated with future electronics: students, graduates, educators, and researchers, as well as managers, investors, and policy makers. Introduction: Towards Sustainable 2020 Nanoelectronics.- From Microelectronics to Nanoelectronics.- The Future of Eight Chip Technologies.- Analog-Digital Interfaces.- Interconnects and Transceivers.- Requirements and Markets for Nanoelectronics.- ITRS: The International Technology Roadmap for Semiconductors.- Nanolithography.- Power-Efficient Design Challenges.- Superprocessors and Supercomputers.- Towards Terabit Memories.- 3D Integration for Wireless Multimedia.- The Next-Generation Mobile User-Experience.- MEMS (Micro-Electro-Mechanical Systems) for Automotive and Consumer.- Vision Sensors and Cameras.- Digital Neural Networks for New Media.- Retinal Implants for Blind Patients.- Silicon Brains.- Energy Harvesting and Chip Autonomy.- The Energy Crisis.- The Extreme-Technology Industry.- Education and Research for the Age of Nanoelectronics.- 2020 World with Chips.
Optical Properties of Nanostructured Metallic Systems
by Sergio G. RodrigoThe common belief is that light is completely reflected by metals. In reality they also exhibit an amazing property that is not so widely known: under some conditions light flows along a metallic surface as if it were glued to it. Physical phenomena related to these light waves, which are called Surface Plasmon Polaritons (SPP), have given rise to the research field of plasmonics. This thesis explores four interesting topics within plasmonics: extraordinary optical transmission, negative refractive index metamaterials, plasmonic devices for controlling SPPs, and field enhancement phenomena near metal nanoparticles.
Microelectronic Systems
by Albert Heuberger Randolf Hanke Günter Elst Karlheinz Kirsch Janina HeppnerThis book is dedicated to Prof. Dr. Heinz Gerhäuser on the occasion of his retirement both from the position of Executive Director of the Fraunhofer Institute for Integrated Circuits IIS and from the Endowed Chair of Information Technologies with a Focus on Communication Electronics (LIKE) at the Friedrich-Alexander-Universität Erlangen-Nürnberg. Heinz Gerhäuser's vision and entrepreneurial spirit have made the Fraunhofer IIS one of the most successful and renowned German research institutions. He has been Director of the Fraunhofer IIS since 1993, and under his leadership it has grown to become the largest of Germany's 60 Fraunhofer Institutes, a position it retains to this day, currently employing over 730 staff. Likely his most important scientific as well as application-related contribution was his pivotal role in the development of the mp3 format, which would later become a worldwide success. The contributions to this Festschrift were written by both Fraunhofer IIS staff and external project team members in appreciation of Prof. Dr. Gerhäuser's lifetime academic achievements and his inspiring leadership at the Fraunhofer IIS. The papers reflect the broad spectrum of the institute's research activities and are grouped into sections on circuits, information systems, visual computing, and audio and multimedia. They provide academic and industrial researchers in fields like signal processing, sensor networks, microelectronics, and integrated circuits with an up-to-date overview of research results that have a huge potential for cutting-edge industrial applications.
Microelectronic Systems: Circuits, Systems and Applications
by Karlheinz Kirsch Janina HeppnerThis book is dedicated to Prof. Dr. Heinz Gerhäuser on the occasion of his retirement both from the position of Executive Director of the Fraunhofer Institute for Integrated Circuits IIS and from the Endowed Chair of Information Technologies with a Focus on Communication Electronics (LIKE) at the Friedrich-Alexander-Universität Erlangen-Nürnberg.Heinz Gerhäuser's vision and entrepreneurial spirit have made the Fraunhofer IIS one of the most successful and renowned German research institutions. He has been Director of the Fraunhofer IIS since 1993, and under his leadership it has grown to become the largest of Germany's 60 Fraunhofer Institutes, a position it retains to this day, currently employing over 730 staff. Likely his most important scientific as well as application-related contribution was his pivotal role in the development of the mp3 format, which would later become a worldwide success.The contributions to this Festschrift were written by both Fraunhofer IIS staff and external project team members in appreciation of Prof. Dr. Gerhäuser's lifetime academic achievements and his inspiring leadership at the Fraunhofer IIS. The papers reflect the broad spectrum of the institute's research activities and are grouped into sections on circuits, information systems, visual computing, and audio and multimedia. They provide academic and industrial researchers in fields like signal processing, sensor networks, microelectronics, and integrated circuits with an up-to-date overview of research results that have a huge potential for cutting-edge industrial applications.
Models of Science Dynamics
by Peter Van Besselaar Andrea Scharnhorst Katy BörnerModels of Science Dynamics aims to capture the structure and evolution of science, the emerging arena in which scholars, science and the communication of science become themselves the basic objects of research. In order to capture the essence of phenomena as diverse as the structure of co-authorship networks or the evolution of citation diffusion patterns, such models can be represented by conceptual models based on historical and ethnographic observations, mathematical descriptions of measurable phenomena, or computational algorithms. Despite its evident importance, the mathematical modeling of science still lacks a unifying framework and a comprehensive study of the topic. This volume fills this gap, reviewing and describing major threads in the mathematical modeling of science dynamics for a wider academic and professional audience. The model classes presented cover stochastic and statistical models, system-dynamics approaches, agent-based simulations, population-dynamics models, and complex-network models. The book comprises an introduction and a foundational chapter that defines and operationalizes terminology used in the study of science, as well as a review chapter that discusses the history of mathematical approaches to modeling science from an algorithmic-historiography perspective. It concludes with a survey of remaining challenges for future science models and their relevance for science and science policy.
Heparin - A Century of Progress
by Barbara Mulloy Rebecca Lever Clive P. PageHeparins remain amongst the most commonly used drugs in clinical practice. Almost 100 years have passed since the initial discovery of this complex substance and, during this time, understanding of the nature and uses of heparin and related molecules has grown dramatically. The aim of this volume is to summarise the developments that have led to the current status of both heparins as drugs and the field of heparin research, with a focus on the particularly rapid progress that has been made over the past three decades. Individual sections are dedicated to the nature of heparin as a biological molecule, the current approaches and techniques that are used to ensure the safety and reliability of heparin as a medicine, the clinical pharmacology of heparin as an anticoagulant drug, effects and potential applications of heparin aside of those involving haemostasis and, finally, the nature and potential uses of heparin-like materials from both natural and synthetic sources.
Microfluidics
by Bingcheng LinFlow Control Methods and Devices in Micrometer Scale Channels, by Shuichi Shoji and Kentaro Kawai. Micromixing Within Microfluidic Devices, by Lorenzo Capretto, Wei Cheng, Martyn Hill and Xunli Zhang. Basic Technologies for Droplet Microfluidics, by Shaojiang Zeng, Xin Liu, Hua Xie and Bingcheng Lin. Electrorheological Fluid and Its Applications in Microfluidics, by Limu Wang, Xiuqing Gong and Weijia Wen. Biosensors in Microfluidic Chips, by Jongmin Noh, Hee Chan Kim and Taek Dong Chung. A Nanomembrane-Based Nucleic Acid Sensing Platform for Portable Diagnostics, by Satyajyoti Senapati, Sagnik Basuray, Zdenek Slouka, Li-Jing Cheng and Hsueh-Chia Chang. Optical Detection Systems on Microfluidic Chips, by Hongwei Gai, Yongjun Li and Edward S. Yeung. Integrated Microfluidic Systems for DNA Analysis, by Samuel K. Njoroge, Hui-Wen Chen, Małgorzata A. Witek and Steven A. Soper. Integrated Multifunctional Microfluidics for Automated Proteome Analyses, by John K. Osiri, Hamed Shadpour, Małgorzata A. Witek and Steven A. Soper. Cells in Microfluidics, by Chi Zhang and Danny van Noort. Microfluidic Platform for the Study of Caenorhabditis elegans,by Weiwei Shi, Hui Wen, Bingcheng Lin and Jianhua Qin.
Secretions and Exudates in Biological Systems
by František Baluška Jorge M. VivancoSecretions and emissions in biological systems play important signaling roles within the organism but also in its communications with the surrounding environment. This volume brings together state-of-the-art information on the role of secretions and emissions in different organs and organisms ranging from flowers and roots of plants to nematodes and human organs. The plant chapters relate information regarding the biochemistry of flower volatiles and root exudates, and their role in attracting pollinators and soil microbial communities respectively. Microbial chapters explain the biochemistry and ecology of quorum sensing and how microbial communities highly co-adapted to plants can aid in bio-energy applications by degrading ligno-cellulosic materials. Other chapters explain the biology of secretions by nematodes, algae and humans, among other organisms. This volume will be a welcome addition to the literature, as no other book covers aspects related to biological secretion in such a holistic and integrative manner.
Receptor-like Kinases in Plants
by Birgit Kemmerling Frans TaxSequencing projects have revealed the presence of at least several hundred receptor kinases in a typical plant genome. Receptor kinases are therefore the largest family of primary signal transducers in plants, and their abundance suggests an immense signaling network that we have only just begun to uncover. Recent research findings indicate that individual receptor kinases fulfill important roles in growth and development, in the recognition of pathogens and symbionts or, in a few examples, in both growth and defense. This volume will focus on the roles of receptor kinases, their signaling pathways, and the ways in which these important signaling proteins are regulated.
Clinical Cardiac MRI (Medical Radiology)
by Andrew M. Taylor Vivek Muthurangu Jan Bogaert Steven DymarkowskiClinical Cardiac MRI is a comprehensive textbook intended for everyone involved in magnetic resonance imaging of the heart. It is designed both as a useful guide for newcomers to the field and as an aid for those who routinely perform such studies. The first edition, published in 2004-5, was very well received within the cardiac imaging community, and has generally been considered the reference because of its completeness, its clarity, and the number and quality of the illustrations. Moreover, the addition of a CD-ROM showing 50 real-life cases significantly enhanced the value of the book. In this second edition, the aim has been to maintain the same quality while incorporating the newest insights and developments in this rapidly evolving domain of medical imaging. The four editors, all experts in the field, have taken great care to ensure a homogeneous high standard throughout the book. Finally, the selection of 100 real-life cases, added as online material, will further enhance the value of this textbook.
Seismic Wave Propagation and Scattering in the Heterogeneous Earth: Second Edition
by Haruo Sato Michael C. Fehler Takuto MaedaSeismic waves - generated both by natural earthquakes and by man-made sources - have produced an enormous amount of information about the Earth's interior. In classical seismology, the Earth is modeled as a sequence of uniform horizontal layers (or spherical shells) having different elastic properties and one determines these properties from travel times and dispersion of seismic waves. The Earth, however, is not made of horizontally uniform layers, and classic seismic methods can take large-scale inhomogeneities into account. Smaller-scale irregularities, on the other hand, require other methods. Observations of continuous wave trains that follow classic direct S waves, known as coda waves, have shown that there are heterogeneities of random size scattered randomly throughout the layers of the classic seismic model. This book focuses on recent developments in the area of seismic wave propagation and scattering through the randomly heterogeneous structure of the Earth, with emphasis on the lithosphere. The presentation combines information from many sources to present a coherent introduction to the theory of scattering in acoustic and elastic materials and includes analyses of observations using the theoretical methods developed. The second edition especially includes new observational facts such as the spatial variation of medium inhomogeneities and the temporal change in scattering characteristics and recent theoretical developments in the envelope synthesis in random media for the last ten years. Mathematics is thoroughly rewritten for improving the readability. Written for advanced undergraduates or beginning graduate students of geophysics or planetary sciences, this book should also be of interest to civil engineers, seismologists, acoustical engineers, and others interested in wave propagation through inhomogeneous elastic media.
Principles of Physics
by Hafez A Radi John O RasmussenThis textbook presents a basic course in physics to teach mechanics, mechanical properties of matter, thermal properties of matter, elementary thermodynamics, electrodynamics, electricity, magnetism, light and optics and sound. It includes simple mathematical approaches to each physical principle, and all examples and exercises are selected carefully to reinforce each chapter. In addition, answers to all exercises are included that should ultimately help solidify the concepts in the minds of the students and increase their confidence in the subject. Many boxed features are used to separate the examples from the text and to highlight some important physical outcomes and rules. The appendices are chosen in such a way that all basic simple conversion factors, basic rules and formulas, basic rules of differentiation and integration can be viewed quickly, helping student to understand the elementary mathematical steps used for solving the examples and exercises. Instructors teaching form this textbook will be able to gain online access to the solutions manual which provides step-by-step solutions to all exercises contained in the book. The solutions manual also contains many tips, colored illustrations, and explanations on how the solutions were derived.
Principles of Physics: For Scientists and Engineers (Undergraduate Lecture Notes in Physics)
by Hafez A Radi John O RasmussenThis textbook presents a basic course in physics to teach mechanics, mechanical properties of matter, thermal properties of matter, elementary thermodynamics, electrodynamics, electricity, magnetism, light and optics and sound. It includes simple mathematical approaches to each physical principle, and all examples and exercises are selected carefully to reinforce each chapter. In addition, answers to all exercises are included that should ultimately help solidify the concepts in the minds of the students and increase their confidence in the subject. Many boxed features are used to separate the examples from the text and to highlight some important physical outcomes and rules. The appendices are chosen in such a way that all basic simple conversion factors, basic rules and formulas, basic rules of differentiation and integration can be viewed quickly, helping student to understand the elementary mathematical steps used for solving the examples and exercises.Instructors teaching form this textbook will be able to gain online access to the solutions manual which provides step-by-step solutions to all exercises contained in the book. The solutions manual also contains many tips, coloured illustrations, and explanations on how the solutions were derived.
Multilingual Information Retrieval
by Carol Peters Martin Braschler Paul CloughWe are living in a multilingual world and the diversity in languages which are used to interact with information access systems has generated a wide variety of challenges to be addressed by computer and information scientists. The growing amount of non-English information accessible globally and the increased worldwide exposure of enterprises also necessitates the adaptation of Information Retrieval (IR) methods to new, multilingual settings. Peters, Braschler and Clough present a comprehensive description of the technologies involved in designing and developing systems for Multilingual Information Retrieval (MLIR). They provide readers with broad coverage of the various issues involved in creating systems to make accessible digitally stored materials regardless of the language(s) they are written in. Details on Cross-Language Information Retrieval (CLIR) are also covered that help readers to understand how to develop retrieval systems that cross language boundaries. Their work is divided into six chapters and accompanies the reader step-by-step through the various stages involved in building, using and evaluating MLIR systems. The book concludes with some examples of recent applications that utilise MLIR technologies. Some of the techniques described have recently started to appear in commercial search systems, while others have the potential to be part of future incarnations. The book is intended for graduate students, scholars, and practitioners with a basic understanding of classical text retrieval methods. It offers guidelines and information on all aspects that need to be taken into consideration when building MLIR systems, while avoiding too many 'hands-on details' that could rapidly become obsolete. Thus it bridges the gap between the material covered by most of the classical IR textbooks and the novel requirements related to the acquisition and dissemination of information in whatever language it is stored.
German Corporate Governance in International and European Context
by Ingo Saenger Otto Sandrock Bernhard Großfeld Claus Luttermann Matthias Casper Jean J. du PlessisCorporate governance encompasses the free enterprise system, which is treated comprehensively in this book from a German perspective. This distinguishes the book from other books written in English in this subject area, not only because of the comprehensive way it covers German corporate law and corporate governance, but also because of the fact that it provides international and European perspectives on these important topics. This second edition is an extensively revised and updated version of the first edition, in particular with a view to the worldwide debt crisis. The authors provide readers with an overview of the unique features of German business and enterprise law and an in-depth analysis of the organs of governance of German public limited companies (general meeting, management board, supervisory board). In addition, approaches for reforms required at the international level are also suggested and discussed, including, among others, the unique interplay and dynamics of the German two-tier board model with the system of codetermination, referring to the arrangement of employees sitting on the supervisory boards of German public limited companies and private companies employing more than 500 employees; also covered are significant recent legal developments in Europe. The book highlights the core function of valuation and financial reporting at the international, European and German levels, with accounting as the documentary proof of good corporate governance. It also expands the scope of the first edition by a treatment of the German financial sector, global corporate finance and governance, and by including a new chapter on compliance of corporate governance laws, rules and standards in Germany. As far as comparative law is concerned, new developments in the area of corporate governance in the EU, the OECD Principles of Corporate Governance and corporate governance in the US, the UK and Australia are covered. The book is addressed to researchers, practitioners and basically anyone with an interest in the complex, but intriguing areas of corporate law and corporate governance.
Learning Neuroimaging
by Francisco de Bravo-Rodríguez Luiz Celso Hygino Da Cruz Jr. Rocío Diaz-AguileraThis book is intended as an introduction to neuroradiology and aims to provide the reader with a comprehensive overview of this highly specialized radiological subspecialty. One hundred illustrated cases from clinical practice are presented in a standard way. Each case is supported by representative images and is divided into three parts: a brief summary of the patient's medical history, a discussion of the disease, and a description of the most characteristic imaging features of the disorder. The focus is not only on common neuroradiological entities such as stroke and acute head trauma but also on less frequent disorders that the practitioner should recognize. Learning Neuroimaging: 100 Essential Cases is an ideal resource for neuroradiology and radiology residents, neurology residents, neurosurgery residents, nurses, radiology technicians, and medical students.
Metals and Society
by Nicholas Arndt Clément GaninoIn the second edition Steve Kesler (University of Michigan) has been added as an author to rewrite some chapters. The motivation for this revised edition is to more intensively address economic issues that surround the exploitation of mineral resources. This emphasis gives the book a unique character. With these sections Metals and Society deals with issues that pervade much of current science reporting - the rate of exploitation of natural resources, the question of when or if these resources will be exhausted, the pollution and social disturbance that accompanies mining, the compromises and challenges that arise from the explosion of demand from China, India and other rapidly developing countries, and the moral issues that surround mining of metals in lesser developed countries for consumption in the "first-world" countries. With its dual character, the book will be useful as an introductory text for students in the earth sciences and a reference volume for students, teachers and researchers of geography, economics and the social sciences.
Dynamische Disposition
by Timm GudehusDie dynamische Disposition ermöglicht marktgerechte Lieferzeiten und kostenoptimale Lieferfähigkeit, sie verhindert überhöhte oder unzureichende Bestände. In dem Buch werden Strategien, Algorithmen und Verfahren der dynamischen Auftrags-, Bestands- und Fertigungsdisposition allgemein verständlich beschrieben und anhand von Beispielen demonstriert. Mithilfe des Regelwerks kann die dynamische Disposition in allen Branchen organisiert und implementiert werden. Die erweiterte 3. Auflage zeigt Potenziale für Serviceverbesserung und Kosteneinsparung auf.
Abgründe der Informatik: Geheimnisse und Gemeinheiten
by Alois PottonWas Sie schon immer über die Informatik und "die Informatiker" wissen wollten, aber nie zu fragen wagten, Alois Potton hat es notiert: Über mehr als zwei Jahrzehnte hat er hinter die Kulissen geblickt und Anekdoten in 80 Glossen gegossen. Schonungslos, bösartig und zum Teil politisch nicht ganz korrekt analysiert er den alltäglichen Wahnsinn und die Absurditäten der IT-Szene. Allgemein verständlich geschrieben, werden sich auch Nichtinformatiker angesichts analoger Vorgänge in ihrem Arbeitsbereich amüsieren - oder aber beleidigt fühlen.
Shock Waves Science and Technology Library, Vol. 6
by F. ZhangThis book, as a volume of the Shock Wave Science and Technology Reference Library, is primarily concerned with the fundamental theory of detonation physics in gaseous and condensed phase reactive media. The detonation process involves complex chemical reaction and fluid dynamics, accompanied by intricate effects of heat, light, electricity and magnetism - a contemporary research field that has found wide applications in propulsion and power, hazard prevention as well as military engineering. The seven extensive chapters contained in this volume are: - Chemical Equilibrium Detonation (S Bastea and LE Fried) - Steady One-Dimensional Detonations (A Higgins) - Detonation Instability (HD Ng and F Zhang) - Dynamic Parameters of Detonation (AA Vasiliev) - Multi-Scaled Cellular Detonation (D Desbordes and HN Presles) - Condensed Matter Detonation: Theory and Practice (C Tarver) - Theory of Detonation Shock Dynamics (JB Bdzil and DS Stewart) The chapters are thematically interrelated in a systematic descriptive approach, though, each chapter is self-contained and can be read independently from the others. It offers a timely reference of theoretical detonation physics for graduate students as well as professional scientists and engineers.
Disorders of Sex Development
by John M. Hutson Garry L. Warne Sonia R. GroverThe rapid advances in medicine over the last 50 years have totally changed the outlook for children with disorders of sex development (DSD), but there is still much to learn. This book crystallizes the combined experience of a leading dedicated unit over 25 years in delivering expert medical and surgical care to children with DSD in a holistic environment. It documents the most recent advances in the molecular biology and embryology of sex development, and describes each disorder in detail. The clinical presentation and approach to diagnosis are described both for babies and for children presenting later in childhood or at adolescence. The chapters on management highlight all the latest knowledge and include the shared wisdom of the authors on current controversies, such as the timing of surgical treatment. Finally, the authors describe their short-, medium-, and long-term outcomes, which demonstrate the strengths of holistic team management.
IRobot - uMan
by Ulrich Furbach Ulrike BarthelmeßWarum werden Roboter oft als bedrohlich empfunden? Können künstliche Systeme Emotionen und Bewusstsein haben? Die Autoren gehen von der These aus, dass die Literatur- und Geistesgeschichte uns helfen kann, aktuelle Entwicklungen der Robotik unvoreingenommen zu betrachten. Denn ob es um mittelalterliche Mythen, androide Roboter der Romantik, die Aufklärung oder die Entwicklung der künstlichen Intelligenz geht, stets stellt sich die Frage nach dem, was der Mensch ist, was sein Bewusstsein ausmacht und was ihn von anderen Wesen unterscheidet.
Copper Zinc Tin Sulfide Thin Films for Photovoltaics: Synthesis and Characterisation by Electrochemical Methods (Springer Theses)
by Jonathan J. ScraggJonathan Scragg documents his work on a very promising material suitable for use in solar cells. Copper Zinc Tin Sulfide (CZTS) is a low cost, earth-abundant material suitable for large scale deployment in photovoltaics. Jonathan pioneered and optimized a low cost route to this material involving electroplating of the three metals concerned, followed by rapid thermal processing (RTP) in sulfur vapour. His beautifully detailed RTP studies - combined with techniques such as XRD, EDX and Raman - reveal the complex relationships between composition, processing and photovoltaic performance. This exceptional thesis contributes to the development of clean, sustainable and alternative sources of energy
Morphogenesis and Pathogenicity in Fungi
by José Pérez Martín Antonio Di PietroInfectious fungal diseases continue to take their toll in terms of human suffering and enormous economic losses. Invasive infections by opportunistic fungal pathogens are a major cause of morbidity and mortality in immuno-compromised individuals. At the same time, plant pathogenic fungi have devastating effects on crop production and human health. New strategies for antifungal control are required to meet the challenges posed by these agents, and such approaches can only be developed through the identification of novel biochemical and molecular targets. However, in contrast to bacterial pathogens, fungi display a wealth of "lifestyles" and modes of infection. This diversity makes it extremely difficult to identify individual, evolutionarily conserved virulence determinants and represents a major stumbling block in the search for common antifungal targets. In order to activate the infection programme, all fungal pathogens must undergo appropriate developmental transitions that involve cellular differentiation and the introduction of a new morphogenetic programme. How growth, cell cycle progression and morphogenesis are co-ordinately regulated during development has been an active area of research in fungal model systems such as budding and fission yeast. By contrast, we have only limited knowledge of how these developmental processes shape fungal pathogenicity, or of the role of the cell cycle and morphogenesis regulators as true virulence factors. This book combines state-of-the-art expertise from diverse pathogen model systems to update our current understanding of the regulation of fungal morphogenesis as a key determinant of pathogenicity in fungi.
Empirical Modelling in Regional Science
by Timo MitzeEconomic agents interact in structural relationships through time and space. This work starts from the empirical observation that all three dimensions, namely time, space, and structural functional forms, are important for an integrative framework of modern empirical analysis in regional science. The work thus aims at combining up-to-date econometric tools from the fields of spatial econometrics, panel time-series analysis and structural simultaneous equation modelling to analysis the different research questions at hand. Most of the topics dealt within this work start from a concrete empirical problem, while problem solving also aims at generating some new knowledge in a methodological way, e.g. by the complementary use of Monte Carlo simulation studies to compare the empirical performance of different estimators for specific data samples. Following a first introductory chapter, the work is structured in three parts addressing major issues in building up a stylized regional economic model such as interregional migration, factor and final demand estimation. All empirical applications use German regional data.