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microRNAs in Toxicology and Medicine

During the past decade it has become evident that microRNAs regulate gene expressions and control many developmental and cellular processes in eukaryotic organisms. Recent studies suggest that microRNAs play an important role in toxicogenomics and are likely to play an important role in a range of human diseases including cancer. microRNAs in Toxicology and Medicine is a comprehensive and authoritative compilation of up-to-date developments in this emerging research area, presented by internationally recognized investigators. It focuses on the role of microRNA in biology and medicine with a special emphasis on toxicology. Divided into six parts, topics covered include:microRNA and toxicology - including environmental toxicants and perturbation of miRNA signaling; microRNA, and Disease States featuring microRNAs in drug-induced liver toxicity, microRNAs and Inflammation the regulatory role of microRNA in mutagenesis, microRNAs and cancer, and the role of microRNAs in tumor progression and therapy, as well as current understanding of microRNAs as therapeutic targets in cancermicroRNAs and disease statesmicroRNAs and stem cellsmicroRNAs and genomicsmicroRNAs and epigenomicsmicroRNAs and biomarkers - including body fluid microRNAs as toxicological biomarkers, cell-free microRNAs as biomarkers in human diseases, and circulating microRNAs as biomarkers of drug-induced pancreatitismicroRNAs in Toxicology and Medicine is an essential insight into the current trends and future directions of research in this rapidly expanding field for investigators, toxicologists, risk assessors, and regulators in academia, medical settings, industry, and government.

Copyright: 2014

ISBN: 9781118696033

Features: Contains images

microRNA: Medical Evidence

by Gaetano Santulli

This volume explores microRNA function in a wide array of human disorders, providing a clinical basis for precision medicine and personalized therapies using these molecules. The twenty-one chapters, all authored by internationally-renowned experts, open with an introduction contextualizing microRNA manipulation within today's initiatives towards precision medicine. The following chapters explore the clinical role of microRNAs in the diagnosis and treatment of metabolic and cardiovascular disorders, focusing on mitochondrial fitness, arterial hypertension, cardiovascular remodeling, cerebrovascular disease, pulmonary hypertension, diabetic kidney disease, and kidney transplantation. The subsequent chapters discuss the importance of microRNAs in the wound healing process and in skin disease, in the pathogenesis of allergy, in human ovulation, and in infection. The book concludes with chapters which outline the emerging role of microRNAS in doping and detail microRNA profiling. microRNA: Medical Evidence is an ideal companion to both microRNA: Basic Scienceand microRNA: Cancer. Taken together, these three books provide a state-of-the-art overview of this rapidly-expanding and fascinating field, from the molecular level to clinical practice. It will be invaluable to medical students, physicians, and researchers, as a complete and unique guide in the exploration of microRNA in basic science, cancer and clinical practice.

Copyright: 2015

ISBN: 9783319226712

Features: Contains images

microRNA: Cancer

by Gaetano Santulli

This volume thoroughly explores of the functional role of microRNAs in cancer. It not only expertly describes the molecular mechanisms underlying the malignant transformation process but also compiles cutting-edge research on microRNAs in several forms of cancer, including colorectal cancer, pancreatic cancer, leukemia/lymphoma, prostate cancer, lung cancer, ovarian cancer, and bone cancer. Distinguished experts, currently working in prestigious institutions, elegantly discuss these fundamental themes. The text, which opens with a foreword by the renowned Dr. Carlo M. Croce, is enhanced by abundant color photographs, schemes, diagrams, and tables that fully support and complement the content. microRNA: Cancer is an ideal companion to both microRNA: Basic Science andmicroRNA: Medical Evidence. Taken together, these three books provide a state-of-the-art overview of this rapidly-expanding and fascinating field, from the molecular level to clinical practice. It will be invaluable to medical students, physicians, and researchers, as a complete and unique guide in the exploration of microRNA in basic science, cancer and clinical practice.

Copyright: 2015

ISBN: 9783319237305

Features: Contains images

microRNA: Basic Science

by Gaetano Santulli

This volume explores microRNA pathophysiology, focusing on basic concepts in molecular and cellular biology. Chapters contributed by leading scientists examine recently discovered pathways in several processes, including aging, diabetes, cardiovascular disease, hematopoiesis, and mitochondrial fitness. The authors contextualize microRNAs within epigenetics and micropeptidomics, angiongenesis and atherosclerosis, endometrial pathophysiology, and more. Throughout, numerous color photographs, diagrams of molecular pathways, and tables enhance the text. microRNA: Basic Science is an ideal companion to both microRNA: Medical Evidenceand microRNA: Cancer. Taken together, these three books provide a state-of-the-art overview of this rapidly-expanding and fascinating field, from the molecular level to clinical practice. It will be invaluable to medical students, physicians, and researchers, as a complete and unique guide in the exploration of microRNA in basic science, cancer and clinical practice.

Copyright: 2015

ISBN: 9783319223803

Features: Contains images

microDomination

by Trevor Young

How to harness your passion, develop your platform, and build a community of fans to sustain your micro-businessIf you dream of launching your own business, but aren't sure what that business should be, microDomination has the answer. This new book from entrepreneur and communications guru Trevor Young, shows you how to tap into your particular area of expertise and build a small business around what you know and love. No matter what particular subject you're knowledgeable in, from dog training to cooking to financial planning, microDomination shows you how to build a brand around yourself and turn that brand and expertise into profits even from the comfort of your own home.In the first part of the book, Young uses real-life examples to introduce you to the businesspeople--or "micro mavens"--who are living their dreams and earning money doing what they love. The second part of the book reveals the nuts-and-bolts strategies and tactics you can use to emulate their success and achieve your goal of "microdominating."Includes inspirational case studies and practical advice on starting a micro-business based on your talent or expertiseFeatures actionable guidance on using content marketing and social media to grow your brand and businessWritten by a leading thinker in the fields of public relations, marketing, and communicationsIf you're stuck in a dead-end job or just dream of turning your hobby into a business, microDomination gives you a proven plan for turning your passion into prosperity.

Copyright: 2013

ISBN: 9781118505656

Features: Contains images

micro: Building STEAM Projects with Code Club and Kids' Maker Groups

by Martin Tan

Build different components of larger systems using class sets of micro:bits with Python in a truly collaborative way. First you’ll explore ways to harness the capabilities of the humble micro:bit and learn to creatively overcome some of its limitations; learning practical text-based programming along the way. We’ll then move on to building projects that allow multiple micro:bits, and other microcontroller boards and parts like the Raspberry Pi, to communicate with one another, and coordinate their operations to build larger systems.Rather than just being a guide to learning these skills, this book will include tips and stories about implementing the these ideas in classrooms, Code Clubs, and Maker environments. Practical logistics for preparation and easy set-up, as well as, acceptance criteria and accountability for students and participants is included. These ideas were gained over years of running a Code Club and running Maker workshops and events.You’ll learn about programming collaborative solutions and design logic. Then you’ll scale that logic up to more complex projects. By the end, you’ll have added additional electronic and physical components to projects that interact with the world. You’ll create fun inventions together, using hardware, coding, electronics, physical objects, and e-textiles.What You'll LearnSolve problems and create art by modelling solutions and ideas with a combination of Python coding, electronic systems engineering, and creative design.Navigate the logistical and unique challenges that come with running your own Code Club, Makerspace, or feeding these activities into STEAM design and technology curriculums.Take new Makers from simply copying and duplicating through to debugging and understanding.Who This Book Is ForMakers and instructors interested in starting group projects while learning to code and gain other Maker skills along the way. Essential information is provided in a form that enables beginners and intermediate Makers to get hands-on quickly, but with enough depth to keep building on these projects and pushing the boundaries.

Copyright: 2023

ISBN: 9781484291979

Features: Contains images

miVisión Lectura, K [Unidad 5] Libro interactivo del estudiante

by María G. Arreguín-Anderson Richard Gómez

NIMAC-sourced textbook

Copyright: 2020

ISBN: 9780328992201