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Mechanics and Materials Science of Biological Materials: Experimental and Modeling Approaches (Materials Horizons: From Nature to Nanomaterials)
by Akarsh Verma Krashn Kumar Dwivedi Piyush UniyalThis book focuses on the important experimental techniques and modeling approaches, with their technological improvements and recent research advancements in the field of biomechanics. The major aim of this book is to cover all updated aspects of biomechanics and materials science of biological materials and its holistic domains including the history, source, formulations and applications. The emphasis is given on the understanding mechanics of soft and hard tissues. Also, many case studies are incorporated in this book that separates it from other related texts.
Food Waste Valorization: Green Techniques in Sustainable Management (Methods and Protocols in Food Science)
by Tanmay SarkarThis volume provides an extensive exploration of innovative and sustainable methodologies for addressing food waste challenges. Chapters detail multiple dimensions, ensuring a comprehensive understanding of food waste valorization through green technologies. Written in the format of the Methods and Protocols in Food Science series, chapters list necessary materials and methods for readily reproducible protocols. Authoritative and cutting-edge, Food Waste Valorization: Green Techniques in Sustainable Management aims to be a valuable resource for academics, researchers, industry professionals, and students focused on sustainable food systems and waste management innovations.
Advances in Intelligent Computing and Communication: Proceedings of ICAC 2024 (Lecture Notes in Networks and Systems #1325)
by Swagatam Das Mihir Narayan MohantyThis book presents high-quality research papers presented at 5th International Conference on Intelligent Computing and Advances in Communication (ICAC 2024) organized by Siksha &‘O&’ Anusandhan, deemed to be university, Bhubaneswar, Odisha, India, in December 2024. This book brings out the new advances and research results in the fields of theoretical, experimental, and applied signal and image processing, soft computing, networking, and antenna research. Moreover, it provides a comprehensive and systematic reference on the range of alternative conversion processes and technologies.
Traum – Subjekt – Gesellschaft: Eine kultursoziologische Betrachtung des nächtlichen Träumens
by Kim Vanessa HagedornDieses Buch fragt nach sozialen und kollektiven Aspekten des nächtlichen Träumens sowie nach dessen Subjektivierungspotenzialen. Die Annäherung erfolgt erstens über das Verhältnis von Traum und Subjekt, zweitens über die Praktiken im Umgang mit Träumen, drittens über das wechselseitige Verhältnis von Traum und Gesellschaft und viertens über das sich Entziehende des Traums. Der wissenschaftshistorische Rahmen erstreckt sich über vier Zeitschnitte entlang von Bezügen zu und Beispielen aus Literatur, Philosophie, Kunst, Spiritismus, Psychologie und Neurowissenschaften vom 18. Jahrhundert bis in die Gegenwart.
Medizindidaktik: Erfolgreich lehren und Wissen vermitteln
by Thomas Kollewe Monika Sennekamp Falk OchsendorfDieser praxisorientierte Leitfaden gibt Lehrenden in medizinischen Studiengängen leicht umsetzbare Werkzeuge an die Hand und hilft dabei, Lehrkompetenz aufzubauen oder den Unterricht noch effektiver zu gestalten. Die vielen Beispiele, Tipps und Anwendungsmöglichkeiten aus verschiedenen Unterrichtsformaten (Seminare, Vorlesungen etc.) sowie die markanten Illustrationen erleichtern den Transfer in die eigene Lehrtätigkeit von der Planung über die Durchführung und Vermittlung der Inhalte bis zum Überprüfen und Bewerten des Lernerfolgs bei den Studierenden. Für die zweite Auflage wurde das Buch auf der Basis aktueller Erkenntnisse der (medizinischen) Lehr-Lern-Forschung aktualisiert und um den Einsatz digitaler Medien erweitert. Es liefert zudem konkrete Hinweise zur Betreuung und Anleitung von Famulanten, PJ´lern oder Studierenden im Blockpraktikum auf der Station und für den Unterricht am Krankenbett.
Robust Control of Jump Linear Stochastic Systems: Applications to Sampled-Data Control (Lecture Notes in Control and Information Sciences #497)
by Vasile Drăgan Samir Aberkane Ioan Lucian PopaThis monograph concentrates on the theory of robust control of linear impulsive stochastic systems and stochastic systems with jumps. It discusses theoretical points concerned with impulsive stochastic systems including optimal control, robust stabilization, and H2- and Hinfinity-type results. Considering the major role played by the impulsive Lyapunov and impulsive Riccati equations in these problems, the book presents a thorough treatment of these equations in a general framework. It also presents various applications to sampled-data control. Robust Control of Jump Linear Stochastic Systems is a self-contained and clearly structured presentation of up-to-date research in this area, relevant to researchers in control theory and to non-specialists who are interested in the theory of robust control of linear impulsive stochastic systems. Theoretical and applied mathematicians, research engineers, and graduate students in the aforementioned fields will also find value in this book.
Non-Destructive Methodologies and Adapted Signal Processing Techniques in the Field of Cultural Heritage (Digital Innovations in Architecture, Engineering and Construction)
by Georgios KaragiannisThis book presents signal processing techniques for analyzing data produced by non-destructive testing methods in conservation science. It explores the complementarity of these techniques in examining art objects, including electromagnetic and mechanical wave-based methods with varying resolutions and penetration depths. The authors also propose a model for integrating multidisciplinary information, supported by real-case reference objects. This book is a valuable resource for professionals in signal processing, cultural heritage, and conservation science.
Mastering Community Management: Chaos, Compassion, and Connections in Games
by Victoria TranGame communities are inevitable – in fact, they’re one of the main features of a game. How can our online interactions be better, kinder, and more productive conversations? How can community managers design online spaces with inherent kindness in mind and create places that encourage member growth and engagement? This book provides a step-by-step strategy for creating long-term, sustainable, and intentional online spaces that matter – ones that care, grow, and connect.Using real-world experience in multiple genres of games, this book covers the fundamental concepts of designing an online community from the core basics of what it is, and then the journey from pre-launch to post-launch. With a deep dive into the practical framework for building stronger communities, it reveals the advantages and reasons why positive, cohesive, and unified spaces are more productive than their less structured counterparts. Additional engagement tips, and why these positive communities drive both business and ethical value, will be explored as an extremely relevant topic for our ever-increasing online world. The content will focus mainly on game communities and independent games, but lessons may be applied to larger studios and industries.Consumers are more inundated with typical marketing schemes than ever, and social media has only become a more powerful, yet chaotic tool over the years. Leave the high-level concepts behind to dig deep and see how community managers can tackle ever-changing algorithms and an entirely digital world. The theories and summaries will also help this book remain timeless – no matter how much social media tools or the internet applications may change, the values and core ways people understand each other and feel belonging will not. Pre-launch to post-launch guide – specifically directed toward activities and strategies for each stage of development. Review activities in key sections to help readers reflect and actively engage with the material. Case studies, step-by-step infrastructure, and background theory will help solidify the framework more practically.
Stranger-Kingship in Antiquity (Routledge Studies in Ancient History)
by Julius Guthrie, Henry Anderson, and Emma NicholsonThis volume introduces the notion of “stranger-kingship” to the field of ancient history and evaluates its use as a new way of thinking about kingship as a political, social, and cultural phenomenon.The chapters highlight the clear and widespread value of the “stranger-king” as a new approach for understanding patterns of political life across time and space in antiquity. The volume begins with theoretical discussions of the “stranger king” and explores how the theory can be mapped onto current thinking about kingship in both Greece and Rome. The chapters then show the multifaceted ways in which this theory can be applied, testing some of its core ideas through case studies that cover Hellenistic monarchy, Greek and Roman kings, the Ptolemies of Egypt, Late Antique Roman emperors, and Ostrogothic Italy and Visigothic Iberia. The volume demonstrates that stranger-kingship has much to offer studies of ancient kingship as a heuristic tool, providing avenues for future research.Stranger-Kingship in Antiquity provides a fascinating cross-cultural study of "stranger kings", of interest to students and scholars in classical studies and the history of the ancient Mediterranean world.
Racial Segregation and Eugenical Science Between the Wars: Race and Racism in Western Science and Society, Volume 2
by Michael L. BlakeyThis volume examines the rise and decline of racial science and its relationship to the political and social imposition of Jim Crow in the American South, a racialized code of laws grounded upon an inherently racist and prejudicial pseudoscience. The author argues, here, that the study of human beings within the emerging 18th‑ and 19th‑century institutions of Western science was corrupted by the limited social intuitions of its enslaving, colonizing, and elitist members. Western science and White societies plowed forward in continued ideological adherence to a biodeterministic imagination: to justify slavery, then Jim Crow racial segregation, immigration restriction, and other deadly and exploitative "eugenical" solutions of Social Darwinist thought. The story is further complexified by the countervailing theories and voices of Black and Jewish intellectuals in the social and biocultural sciences in the 19th and 20th centuries such as Frederick Douglass, W.E.B. Du Bois, and Montague Cobb. These had profound consequences not only for the social sciences but also for the cultural life of Black Americans in the aftermath (and afterlife) of slavery. At the same time, even here, the author discloses that the racialized dimensions of social science could not be fully exorcised, as social science continued to construct "soft‑line racism" in that it selectively primitivized darker people and omitted White racism and colonialism from their human story. African American social scientists and historians brought White racism and Black modernity to the fore. Eugenics had begun to paint marginal White people (Jewish and Italian immigrants to the United States) as natural inferiors to "Nordics" or "Aryans" with devastating consequences in World War II Europe. As the War ended, the world community began its turn against racism in science and society. In constructing this historical and sociological counternarrative, the author provides a critical new social history that illuminates a tangled and turgid past for contemporary readers, students, and researchers with vital insights for anthropology, sociology, history, cultural studies, philosophy, and American studies.
Socially Engaged Art and Ethics: Power, Politics and Participation
by Anthony SchragBringing together artists, curators, activists, academics, managers, and educators from around the world, this unique anthology examines the notion of ethics within socially engaged art. The volume aims to deepen conversations around what ‘good’ or ‘right’ activities could be in this developing and expanding practice, and readers are invited to consider the contextual nature of socially engaged art – its politics, infrastructures and values. Supported by case studies from the United Kingdom, the United States, China, Cuba, South Africa, and Norway, as well as discussions relating to education, cultural policy, and activism, this volume provides a much-needed critical analysis in the making, curating, commissioning and managing of socially engaged art. This collection is an ideal text for interdisciplinary courses that place visual arts (including design or performance) within social and political contexts but also for students and scholars of art, art history and visual studies more generally.
Motor Behavior: Control, Learning and Development
by João Barreiros Pedro PassosMotor Behavior: Control, Learning and Development explores the realm of Motor Behavior, a field intricately examining human action and movement across a lifetime – from their initial acquisition to refinement and evolution. This discipline provides a profound lens through which we comprehend the complex dynamics of human physicality.Presented across four sections, each progressively guiding the reader from fundamental insights into the workings of the human body to more intricate subjects pertaining to motor control and learning, Motor Behavior: Control, Learning and Development equips readers with a comprehensive understanding of the intricate mechanisms governing the human body during movement. Additionally, this book clarifies current perspectives on control and learning. Recognizing the perpetual evolution of science, there are short stories interspersed throughout the text. These narratives contextualize the unfolding tapestry of scientific knowledge, encouraging readers to adopt an open-minded stance toward the topic.Tailored for students navigating the academic terrain in both bachelor's and master's degrees, this cutting-edge new textbook is essential reading for all students in Motor Control, Motor Learning, Motor Development, Skill Acquisition courses, and related modules.
The Early Seventeenth Century Verse Miscellany: Directions and Re-Directions (Material Readings in Early Modern Culture)
by Cedric C. BrownA deeply researched study of the social transmission and adaptation of poetry texts originating in pre-Civil War England, traced through the seventeenth century and sometimes beyond. Both manuscript and printed miscellanies are used, as well as other forms of publication, and case studies unusually span elite, popular and provincial audiences. As far as possible, texts are placed according to their original contexts and functions (“Directions”) then followed through various answerings, parodies, co-optings and social, commercial and political adaptations (“Re-directions”). Case studies choose examples which have not been fully researched, so that a large amount of new material is presented from poets writing in a variety of environments. Results are sometimes startling and often amusing, giving a vivid sense of how poems were read and used in material exchange and providing a picture of literary activity far removed from what traditional, canonical literary history has often assumed.
Patents and Global Administrative Law: Values, Principles, and Challenges
by David TiltThe book applies values and concepts from Global Administrative Law (GAL) to international patent law, demonstrating how limiting technocratic and overly economic language can be. Highlighting the administrative foundations of patent law, the book argues that, in its international form, it can be analysed using the same principles of participation, transparency, and accountability found in national administrative law.At the heart of the book is a simple question: What does international patent law look like when we approach it through the lens of these values? What is being left out when patent law is described predominantly in terms of its technical legal provisions or economic impact? The book presents three interrelated contexts: EU patent law, bilateral trade agreements, and the multilateral space. Modern patent law is increasingly discussed in terms of national competitiveness or economic potential, which reveals only a narrow understanding of how patent law evolves and functions. The vocabulary of administrative law provides a fresh way of recasting, reframing, and re-describing the dynamics of international patent law in a way that is more accessible to those outside of a traditional patent scholarship audience. A fundamental objective of the book is to challenge the tendency towards technocratic isolation in patent law. The book uses accessible vocabulary and represents a new way of conceptualising and understanding how patent law develops on a global scale.The book will be of interest to researchers in the field of patent law, international law, and administrative law.
Sexuality, Nudity and the Body in Soviet Cinema (Routledge Contemporary Russia and Eastern Europe Series)
by Beumers, Edited by BirgitThis book explores evocations of and allusions to sexual desire in Soviet cinema, 1919–1991.By deploying several lines of investigation – from the cult of the masculine, strong body in Stalinist cinema to the shifting signification of the naked body (male and female) in post-war cinema and to the display of a sexualised body in the late Soviet era – this book establishes the extent to which Soviet cinema actually did reveal sexuality. It also explores how external political and social factors impacted representation. Overall, the contributions challenge the narrative of Soviet cinema as an art form where the representation of sexuality was taboo and outline shifts in the concepts of the naked and sexualised body, of sexuality and sexual relationships.This book will be of interest to scholars and researchers in the field of film studies, Slavic and Soviet studies, cultural studies, politics and gender studies.
How Autocrats Are Held Accountable: Resistance to Trump and Trumpism (Defending American Democracy)
by Richard L. AbelChronicling and analyzing resistance to the threat that autocracy poses to American liberal democracy, this book provides the definitive account of the roles that courts and elections played in holding Trump accountable for his actions.This book describes the many lawsuits brought against Trump and his supporters for their autocratic actions. Trump was found liable in two civil lawsuits: for nearly $100 million for sexually abusing and defaming E. Jean Carroll and for nearly $500 million for fraudulently valuing his real estate properties. Trump supporters and associates suffered even greater liabilities for defamation. And many of his lawyers were disciplined by professional associations. New York successfully prosecuted Trump for falsifying business records in connection with hush money payments to Stormy Daniels. Georgia obtained guilty pleas from four Trump associates implicated in efforts to change that state’s electoral votes, although the case against Trump was derailed by prosecutorial misconduct. Special Counsel Jack Smith initiated two prosecutions against Trump: for concealing classified papers and for seeking to overturn the 2020 election. But the Supreme Court created a novel doctrine of presidential immunity; and those cases were dismissed before Trump’s second inauguration. The book also analyzes the 2024 election, which Trump won with a bare 1.5 percent majority. It exposes his intensifying vilification of immigrants and transgender people and the numerous falsehoods he and his supporters disseminated. The book concludes by evaluating all the varied forms of resistance to autocracy described in the five volumes of the Defending American Democracy mini-series.This definitive account and analysis of Trumpism and the resistance to it will appeal to scholars, students, and others with interests in politics, populism, and the rule of law and, more specifically, to those concerned with resisting the threat that autocracy poses to liberal democracy.
The Extra-Ordinary Girl: Care, Connection, and Social Power On and Off Screen (Routledge Research in Cultural and Media Studies)
by Tina Belinda BenignoPositioning the teen girl as a figure possessing exceptional power with the potential to instigate change, this book examines the “extra-ordinary” girl as she exists under neoliberalism today.Through a combination of textual and cultural analyses of figurations of girlhood in popular culture, and qualitative research group interviews with teen girls, the author emphasizes the importance of listening to real teen girls whose perspectives and values might not match those attributed to dominant cultural models of girlhood. This book explores contemporary girl figures and figurations of girlhood, on and off screen, highlighting how girls who are not in the public eye negotiate standards of exceptionality in relation to their own experiences of social power, while also defining the importance of care and connection to their relationships and personal values.This book is a unique and comprehensive combination of methodological and conceptual approaches to cultural, historical, and sociological analyses, while exploring questions of feminism and the speculative fiction genre. It will appeal to girlhood and feminist studies, film and media studies, child and youth studies, humanities, cultural studies, and social sciences.
Graph Machine Learning: Learn about the latest advancements in graph data to build robust machine learning algorithms
by Claudio Stamile Aldo Marzullo Enrico DeusebioEnhance your data science skills with this updated edition featuring new chapters on LLMs, temporal graphs, and updated examples with modern frameworks, including StellarGraph, PyTorch Geometric, and DGLKey FeaturesMaster new graph ML techniques through updated examples using PyTorch Geometric and Deep Graph Library (DGL)Explore GML frameworks and their main characteristicsLeverage LLMs for machine learning on graphs and learn about temporal learningPurchase of the print or Kindle book includes a free PDF eBookBook DescriptionGraph Machine Learning, Second Edition builds on its predecessor’s success, delivering the latest tools and techniques for this rapidly evolving field. From basic graph theory to advanced ML models, you’ll learn how to represent data as graphs to uncover hidden patterns and relationships, with practical implementation emphasized through refreshed code examples. This thoroughly updated edition replaces outdated examples with modern alternatives such as PyTorch and DGL, available on GitHub to support enhanced learning. The book also introduces new chapters on large language models and temporal graph learning, along with deeper insights into modern graph ML frameworks. Rather than serving as a step-by-step tutorial, it focuses on equipping you with fundamental problem-solving approaches that remain valuable even as specific technologies evolve. You will have a clear framework for assessing and selecting the right tools. By the end of this book, you’ll gain both a solid understanding of graph machine learning theory and the skills to apply it to real-world challenges.What you will learnImplement graph ML algorithms with examples in StellarGraph, PyTorch Geometric, and DGLApply graph analysis to dynamic datasets using temporal graph MLEnhance NLP and text analytics with graph-based techniquesSolve complex real-world problems with graph machine learningBuild and scale graph-powered ML applications effectivelyDeploy and scale your application seamlesslyWho this book is forThis book is for data scientists, ML professionals, and graph specialists looking to deepen their knowledge of graph data analysis or expand their machine learning toolkit. Prior knowledge of Python and basic machine learning principles is recommended.
Sino-Pakistan Partnership Under the China-Pakistan Economic Corridor and the Burden of Expectations (Politics and Development of Contemporary China)
by Murad AliThis book has come up with the most up-to-date, comprehensive and objective analysis of China&’s investments in Pakistan under the China-Pakistan Economic Corridor, a flagship project of the Belt and Road Initiative. It covers the broad range of Sino-Pakistan relations in the backdrop of Pakistan&’s complex political, governance, security, socio-environmental and technological challenges that hinder implementation of CPEC projects. Backed by robust empirical evidence, a unique feature of this volume is that it demystifies several myths about CPEC concerning &‘debt-trap&’ narrative, China&’s &‘win-win&’ proposition and Pakistan&’s mantra of &‘game changer&’ and &‘fate changer&’. By examining Chinese infrastructure-building initiative vis-à-vis competing economic initiatives such as the US/G7-led Partnership for Global Infrastructure Investment, the Global Gateway strategy of the European Union, and the India-Middle East-Europe Economic Corridor of the G20, a distinctive significance of this book is that it aptly situates the implications of China&’s growing role in Pakistan in broader regional and global context.
A Field Guide to Responsible Investing: Asset Management in the Age of Polycrises
by Amy O'BrienFor years, responsible investing has been a bewildering precinct in asset management. To many, the idea of aligning your values with your investment portfolio seemed naive. Slowly and steadily, responsible investing morphed from a movement into an industry on course to command $50 trillion in assets by 2025— a third of the capital at work in the markets. And yet responsible investing has remained as difficult to traverse as ever. It&’s drawn fire from critics who&’ve branded the approach &“woke capitalism&” whilst more &“responsible&” generations of investors are poised to marshal trillions of assets of their own into the business - we are at an inflection point. As a responsible investing practitioner for more than 25 years, author Amy O&’Brien has taken part in this revolution in asset management. With geopolitical conflicts, economic instability, and climate change fomenting unprecedented &“polycrises&”, she believes there is no more effective way to address the challenges of the 21st century than through responsible investing. Like most tectonic shifts in asset management, responsible investing has been complicated, hard to define, and hard to measure. But doing so is not only possible, it's also imperative. Over nine chapters, the book takes readers on a journey of the evolution of responsible investing, how it works today, why it&’s integral to investment considerations, and how we can finally get a grip on its efficacy. It&’s time to demystify and unpack this invaluable method for managing our assets, and our futures.
Groundwater Resource Management Planning Strategies: A Geospatial Approach: Volume 1 (Springer Water)
by Etikala Balaji Vangala Sunitha Bandi Muralidhara Reddy Yenugu Sudharshan Reddy Mannala Prasad Badapalli Pradeep KumarGeospatial tools to Groundwater Resources explain the most recent methods in Geographic Information Systems (GIS) and geostatistics as they apply to groundwater through complete case studies that demonstrate actual remote sensing applications in this field. Due to the rising demand for water, its decreasing quality, and its limited supply, water resource management has grown to be a serious issue. In many places of the world, groundwater is the main supply of fresh water, but certain areas are growing unduly reliant on it, utilising groundwater more quickly than it can be replenished naturally and resulting in an unceasing decrease in water tables. For the efficient use, management, and modelling of this priceless but diminishing natural resource, systematic planning of groundwater consumption using current approaches is crucial. Remote sensing, GIS, GPS (Global Positioning Systems), and geostatistical approaches are among the effective water management methods that have developed with the introduction of powerful and fast personal computers. Now more than ever, it is possible to analyse with greater accuracy the relationships between environmental elements and human health and wellbeing. Our understanding of the continuum between environment and health consequences on many different sizes, from the global to even the individual, has evolved thanks to a number of transdisciplinary accomplishments. This book covers a wide range of geospatial health-related topics and methods, including climate change, healthcare utilisation, health disparities, air quality assessment, asthma, water quality assessment, and machine learning. It also advances scientific understanding, development, and application of geospatial technologies related to water resource management. Researchers and postgraduate students in Earth and Environmental Sciences, particularly GIS, agriculture, hydrology, natural resources, and soil science, who need to be ableto apply the most recent innovations in groundwater research in a practical way will find Case Studies in Geospatial Applications to Groundwater Resources to be a valuable resource. This edited volume will concentrate on the most recent studies and uses of geospatial methods in water resource management, offering insights into the difficulties and possibilities of applying these methods to solve practical issues.
Circular Economy and Environmental Resilience: Solutions for a Sustainable Tomorrow, Volume 1
by Pardeep Singh Vandana Mishra Shikha Daga Kiran YadavThis book comprehensively covers the contemporary topic of circular economy and its role in promoting environmental resilience and sustainability. It provides extensive coverage by focusing on the existing environmental issues and how circular practices can help mitigate climate change and bring a development that is not only inclusive but also green. It would be thus immensely useful for the industrialists, academicians, researchers and policymakers working in the area of circular practices, sustainability and environmental protection and resilience. The book addresses the issue of environmental resilience and the role that circular economic practices can play in promoting a development that is not only inclusive and green but also sustainable. The book is an immense use to academicians, students, researchers, policymakers and international organisations working in the area of sustainability and circular economy practices.
Ferronematics and Living Liquid Crystals (SpringerBriefs in Physics)
by Sanjay Puri Aditya Vats Varsha BanerjeeThis book delves into the intricate world of soft matter physics, specifically focusing on two contemporary complex systems: ferronematics and living liquid crystals. These systems amalgamate passive and active inclusion in the nematic liquid crystals. From a pedagogical description to advanced dynamics, this book provides a solid foundation for understanding these complex systems. Practical insights through simulations and analytical expressions bridge the gap between theory and real-world applications, making the knowledge gained highly relevant. This book caters to students, researchers, and scholars in the field of soft matter physics. A strong foundation in statistical physics and mathematical physics is recommended, especially in areas related to liquid crystal physics, statistical mechanics and complex systems. The book provides a plethora of theoretical knowledge, simulations, and analytical expressions, serving as an indispensable resource for those eager to delve into the intriguing domains of soft matter physics.
Physical and Biological Barriers at the Interface Between the Gut Microbiome and the Immune System (The Microbiomes of Humans, Animals, Plants, and the Environment #5)
by Marika Falcone Martina Antonini CencicchioThe gut environment is fundamental to the modulation of innate and adaptive immunity, not only in the intestinal mucosa, but systemically. Immune cells constantly circulate through the intestinal tissue and gut-associated lymphoid tissue (GALT), where their phenotype and function are regulated by several factors, including but not limited to the commensal gut microbiota. The host-microbiome interaction, and the role of the gut microbiota in modulating innate and adaptive immunity in the intestinal mucosa and systemically, has been amply described in recent literature and reviews. This contributed volume instead explores the cutting-edge concept that gut microbiota composition is only one of the actors in intestinal immune regulation, and that several other factors -- both genetic and environmental -- modulate innate and adaptive immunity within the intestine. Each chapter in this volume addresses the various intestinal factors modulating immunity, including food components, endogenous metabolites, biological gut barrier components, and enteric neuroimmune circuits, individually and within the context of their integration with systemic components affecting immune cell phenotypes and function. In addition, it will more broadly address the role of the physical and biological barriers as key players in the interaction between immune cells and the intestinal environment, including coverage of cutting-edge in vivo technologies that have allowed the characterization of these interactions. The final chapters are dedicated to understanding how gut environment modifications are involved, and can be therapeutically manipulated in different diseases settings, including targeting the gut environment to regular response in anti-tumor immunity, fighting infections, and controlling autoimmune diseases.
Phoniatrics II: Speech and Speech Fluency Disorders – Literacy Development Disorders (European Manual of Medicine)
by Katrin Neumann Antoinette am Zehnhoff-Dinnesen Joseph Sopko Marie - Claude Monfrais-PfauwadelThis book, in three volumes, draws on the specialized insights and extensive clinical experience of phoniatric experts to offer a basis for the development of concerted European training standards, with the goal of guaranteeing a high quality of phoniatric care for all European patients. Communication disorders in all age groups are covered, and the interdisciplinary character of phoniatrics is mirrored in the inclusion of contributions from a range of other medical and non-medical disciplines. This second volume is devoted to speech, speech fluency and literacy development disorders. Basic aspects, including etiology and pathogenesis, are fully addressed, and guidance provided on diagnostic methods, differential diagnosis, prevention, treatment/rehabilitation, and prognosis. The reader will benefit from numerous color photos, tables as well as supplementary electronic material, including audio and video examples. This book is intended for residents and practitioners in phoniatricsand also for ENT physicians, medical students, logopedists, and speech and language pathologists and therapists.