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Extracellular Matrix in Development
by Robert Mecham Douglas W. DesimoneCells in the developing embryo depend on signals from the extracellular environment to help guide their differentiation. An important mediator in this process is the extracellular matrix - secreted macromolecules that interact to form large protein networks outside the cell. During development, the extracellular matrix serves to separate adjacent cell groups, participates in establishing morphogenic gradients, and, through its ability to interact directly will cell-surface receptors, provides developmental clocks and positional information. This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function. The topics addressed range from how ECM influences early development as well as repair processes in the adult that recapitulate developmental pathways.
Power, Voting, and Voting Power: 30 Years After
by Hannu Nurmi Manfred J HollerThe developments over a thirty-year time span in the study of power, especially voting power, are traced in this book, which provides an up-to-date overview of applications of n-person game theory to the study of power in multimember bodies. Other theories that shed light on power distribution (e.g. aggregation theory) are treated as well. The book revisits the themes discussed in the well-known 1982 publication "Power, Voting and Voting Power" (edited by Manfred J. Holler). Thirty years later this essential topic has been taken up again and many of the authors from its predecessor participate here again in discussing the state-of-the-art, demonstrating the achievements of three decades of intensive research, and pointing the way to key issues for future work.
Neuroeconomics
by Martin Reuter Christian MontagThis book represents one of the cornerstones of the series Studies in Neuroscience, Psychology and Behavioral Economics. It is divided into eight sections, starting with an introduction to neuroeconomics followed by an overview of frequently applied experimental paradigms (games) in neuroeconomics research. Furthermore, it addresses the molecular basis of human decision making, environmental/situational factors and social contexts influencing human decision making, as well as translational and developmental/clinical approaches to neuroeconomics. In closing, a paper on neuro-marketing demonstrates how knowledge from neuroeconomics research can be applied in "real life. " Culminating in an extensive methods section, in which eight different neuroscience techniques are introduced, the book offers an essential resource for researchers and practitioners, and may also be beneficial for graduate students.
Coaching: Angewandte Psychologie für die Beratungspraxis
by Eric LippmannCoaching ist in aller Munde, die Angebote sind zahlreich, der Markt ist mittlerweile von vermeintlich neuen "Tools", Techniken und Ansätzen etc. fast übersättigt und sehr unübersichtlich. Diese Buch hilft, den Überblick zu behalten. Es stellt wirklich relevante Coaching-Ansätze nach einheitlichem Raster vor: Das Wichtigste in Kürze, typische Fragestellungen, Fallbeispiele, Erfolgskriterien für Berater, Besonderheiten einzelner Zielgruppen. Es informiert über wichtige Settings im Coaching-Prozess: Einzeln, in der Gruppe, kollegial, extern oder intern, als Selbst- oder Online-Coaching. Es hilft bei der Abstimmung auf bestimmte Zielgruppen: Coaching für Führungskräfte auf allen Managementebenen, im Familienunternehmen, für Schulleiter oder Lehrer, im Personalmanagement oder in der Politik. Es gibt Tipps für unterschiedliche Anwendungsfelder: Coaching bei Veränderungsprozessen, bei Konflikten, im Rahmen der betrieblichen Bildung, im Umgang mit Medien, bei Laufbahnfragen, bei Freistellungen. Kurz: Es ist ein Standardwerk für Praktiker, geschrieben von Top-Fachleuten der Branche - nun in überarbeiteter dritter Auflage und mit neuen Kapiteln zu psychodynamischen Ansätzen, Diversity-Aspekten oder Coaching im Sport. Mit Serviceteil für Coaches und Coachees: Suche und Auswahl von Coaches, Links für Coaches zu Aus- und Weiterbildungen, Kongressen, Zeitschriften, kommentierte Literaturtipps.
Die hypothetische Einwilligung im Strafrecht
by Nike HengstenbergDie Arbeit setzt sich mit dem Ursprung der hypothetischen Einwilligung im zivilrechtlichen Arzthaftungsrecht auseinander und untersucht ihren schrittweisen Transfer in das Strafrecht. Den Schwerpunkt bildet dabei die kontrovers diskutierte Frage des "Ob" und "Wie" einer dogmatischen Verortung der Rechtsfigur. Nach einer umfassenden Würdigung der hierzu existierenden Legitimationsmodelle sowie der gegen sie vorgebrachten Kritik zeigt die Verfasserin mögliche alternative Lösungsansätze auf, die sodann in ein - an den Vorgaben der Rechtsprechung des BGH orientiertes - praktikables und interessengerechtes Lösungsmodell münden. Dieses beinhaltet neben einer Differenzierung zwischen fahrlässigen und vorsätzlichen Aufklärungsfehlern eine Begrenzung ihres Anwendungsbereichs unter Berücksichtigung der ihr immanenten Grenzen sowie des allgemeinen Missbrauchsgedankens. Abschließend widmet sich die Verfasserin der in der Wissenschaft bislang wenig diskutierten Frage, ob und inwieweit die hypothetische Einwilligung auch jenseits des Arztstrafrechts einen legitimen Anwendungsbereich besitzt.
Chinese Encyclopaedias of New Global Knowledge: Changing Ways of Thought (Transcultural Research – Heidelberg Studies on Asia and Europe in a Global Context)
by Rudolf G Wagner Milena Doleželová-VelingerováThis is a set of pioneering studies on Chinese encyclopaedias of modern knowledge (1870-1930). At a transitional time when modern knowledge was sought after yet few modern schools were available, these works were crucial sources of information for an entire generation. This volume investigates many of these encyclopaedias, which were never reprinted and are hardly known even to specialists, for the first time. The contributors to this collection all specialize in the period in question and have worked together for a number of years. The resulting studies show that these encyclopaedias open a unique window onto the migration and ordering systems of knowledge across cultural and linguistic borders.
Tourism and Hospitality Development Between China and EU
by Guojun ZengTourism and hospitality industry is facing a substantial amount of opportunities and challenges due to the globalization. The Third International Conference on Tourism and Hospitality between China and Spain (ICTCHS) provides a unique global forum for academics, thought leaders and key industry practitioners from diverse backgrounds and interests to meet, discuss and debate critical issues that will affect the future direction of tourism and hospitality research and practice.
Corporate Governance, Capital Markets, and Capital Budgeting: An Integrated Approach (Contributions to Management Science)
by Sardar M. Islam Baliira KalyebaraThe primary contribution of this book is to integrate the important disciplines which simultaneously impact the investment appraisal process. The book presents a study that develops a new approach to investment appraisal which uses a multiple objective linear programming (MOLP) model to integrate the selected disciplines which include capital markets, corporate governance and capital budgeting. The research covers two case studies, one in the e-commerce sector and another in the airline industry in which the above disciplines are integrated. Readers from the areas of corporate governance, regulation, and accounting would find the survey of different approaches and the new integrated optimization approach particularly useful.
A Guide to Continuous Improvement Transformation: Concepts, Processes, Implementation (Management for Professionals)
by Selahattin Kurtoglu Aristide Van AartsengelThis book enables enterprise business leaders - from CEOs to supervisors - to understand what "Continuous Improvement" is, why it is probably the best answer to improved business performance in years, and how to put it to work in the unique environment of a specific organization. The book examines what is at the core of "Continuous Improvement" and delves deeper into the elements and constituents necessary to take an organization to the next level to ensure its continued, long-term existence. It provides guidance to enterprise management and to professionals engaged in the implementation of a "Continuous Improvement" initiative and enables them to structure and manage its implementation successfully. It also provides tools to quickly assess where an enterprise business stands in terms of strategic management and "Continuous Improvement".
Handbook on Continuous Improvement Transformation: The Lean Six Sigma Framework and Systematic Methodology for Implementation
by Selahattin Kurtoglu Aristide Van AartsengelThis handbook provides a comprehensive and detailed framework for the implementation of "Continuous Improvement" and Lean Six Sigma in a professional project management environment. For this purpose the book brings together Lean Six Sigma and the PMBOK standard for project management. It provides an integrated approach, which can be used for both transactional and manufacturing businesses to better define ways to reduce costs, enhance processes ,and achieve faster implementation and new product or service development. The reader is guided carefully and reliably through the detailed procedures introduced in this book using a comprehensive, conceptual and practical well-balanced approach.
Augen-Sprechstunde
by Wolfram Goertz Birgit HartmannGrüner Star, Grauer Star, altersabhängige Netzhaut-Degeneration und durch Diabetes hervorgerufene Netzhautschäden gehören zu den häufigsten Ursachen für starke Sehminderung und Blindheit. Eine frühe Diagnose ist bei diesen Krankheiten entscheidend, um das Sehvermögen zu erhalten. Gegliedert nach Symptomen informiert der Ratgeber über mögliche Erkrankungen und Therapien, wobei alle Fachbegriffe verständlich erklärt werden. Lesern wird dadurch geholfen, richtig einzuschätzen, wie dringend eine augenärztliche Untersuchung anzuraten ist.
ERP-Kompendium
by Wolfgang W. OsterhageERP-Systeme gibt es seit einigen Jahrzehnten. Sie haben sich aus ursprünglich einfachen betriebswirtschaftlichen Programmen zu immer ausgefeilteren hochkomplexen Softwarepaketen entwickelt. Einige ihrer Hersteller zählen heute mit zu den erfolgreichsten börsennotierten Unternehmen. Das Buch beschreibt zunächst die wichtigsten logischen Grundlagen, sodann Funktionalitäten und Lösungen, wie sie in der Wirtschaft gefordert sind. In einem zweiten Teil werden schematisch die heute gängigsten Systeme auf dem Markt vorgestellt und nach festgelegten Kriterien bewertet. Diese Bewertung bietet eine Orientierungshilfe für Interessierte, die solche Systeme einführen bzw. vorhandene in ihren Organisationen ersetzen wollen.
Joint Imaging in Childhood and Adolescence
by Bruno Beber Machado Maria Custódia Machado Ribeiro Sergio Lopes VianaKnowledge of the imaging appearances of the immature joint is crucial for correct image interpretation, yet this is a relatively neglected subject in the literature and in training. This book presents the essential information on imaging of the immature joint with the aim of providing radiologists (musculoskeletal specialists and generalists alike) and other specialists with a new tool that will assist greatly in overcoming the daily challenges posed by interpretation of pediatric examinations in the twenty-first century. The opening chapters consider the current role, advantages, and limitations of each modality in pediatric assessment and present the imaging appearances of anatomic and developmental peculiarities of the growing skeleton. Findings in a wide range of important conditions are then described in a series of richly illustrated chapters that present appearances on diverse imaging studies, from conventional radiography through to modern high-tech modalities.
'Archaeologizing' Heritage?: Transcultural Entanglements between Local Social Practices and Global Virtual Realities (Transcultural Research – Heidelberg Studies on Asia and Europe in a Global Context)
by Michael Falser Monica JunejaThis book investigates what has constituted notions of "archaeological heritage" from colonial times to the present. It includes case studies of sites in South and Southeast Asia with a special focus on Angkor, Cambodia. The contributions, the subjects of which range from architectural and intellectual history to historic preservation and restoration, evaluate historical processes spanning two centuries which saw the imagination and production of "dead archaeological ruins" by often overlooking living local, social, and ritual forms of usage on site. Case studies from computational modelling in archaeology discuss a comparable paradigmatic change from a mere simulation of supposedly dead archaeological building material to an increasing appreciation and scientific incorporation of the knowledge of local stakeholders. This book seeks to bring these different approaches from the humanities and engineering sciences into a trans-disciplinary discussion.
One Health: The Human-Animal-Environment Interfaces in Emerging Infectious Diseases
by John S. Mackenzie Martyn Jeggo Peter Daszak Juergen A. RichtOne Health is an emerging concept that aims to bring together human, animal, and environmental health. Achieving harmonized approaches for disease detection and prevention is difficult because traditional boundaries of medical and veterinary practice must be crossed. In the 19th and early 20th centuries this was not the case--then researchers like Louis Pasteur and Robert Koch and physicians like William Osler and Rudolph Virchow crossed the boundaries between animal and human health. More recently Calvin Schwabe revised the concept of One Medicine. This was critical for the advancement of the field of epidemiology, especially as applied to zoonotic diseases. The future of One Health is at a crossroads with a need to more clearly define its boundaries and demonstrate its benefits. Interestingly the greatest acceptance of One Health is seen in the developing world where it is having significant impacts on control of infectious diseases.
One Health: Food Safety and Security, and International and National Plans for Implementation of One Health Activities (Current Topics in Microbiology and Immunology #366)
by John S. Mackenzie, Martyn Jeggo, Peter Daszak and Juergen A. RichtOne Health is an emerging concept that aims to bring together human, animal, and environmental health. Achieving harmonized approaches for disease detection and prevention is difficult because traditional boundaries of medical and veterinary practice must be crossed. In the 19th and early 20th centuries this was not the case—then researchers like Louis Pasteur and Robert Koch and physicians like William Osler and Rudolph Virchow crossed the boundaries between animal and human health. More recently Calvin Schwabe revised the concept of One Medicine. This was critical for the advancement of the field of epidemiology, especially as applied to zoonotic diseases. The future of One Health is at a crossroads with a need to more clearly define its boundaries and demonstrate its benefits. Interestingly the greatest acceptance of One Health is seen in the developing world where it is having significant impacts on control of infectious diseases.
Managerial Discretion and Performance in China: Towards Resolving the Discretion Puzzle for Chinese Companies and Multinationals
by Hagen WülferthThe theoretical and empirical literature to date has fallen short of reaching a consensus as to whether granting more managerial discretion to managers tends to enhance, not alter or diminish organizational performance (the discretion puzzle). This book aims to build a bridge between these contradictory results by synthesising principal-agent theory, stewardship theory, and managerial discretion theory into a new empirically-validated model. Using a representative sample of 'double-blind' interviews with managers of 467 firms in China and applying partial least squares path modelling (PLS), the study identifies a potential cause of the discretion puzzle: the failure of the extant literature to account for granularity in the way that managers use their discretion. This generates far-reaching implications for theoretical and empirical research as well as practical recommendations for managing managers in multinationals and Chinese companies.
Malpractice and Medical Liability
by Guido Viel Rafael Boscolo-Berto Santo Davide FerraraMedical responsibility lawsuits have become a fact of life in every physician's medical practice. However, there is evidence that physicians are increasingly practising defensive medicine, ordering more tests than may be necessary and avoiding patients with complicated conditions. The modern practice of medicine is increasingly complicated by factors beyond the traditional realm of patient care, including novel technologies, loss of physician autonomy, and economic pressures. A continuing and significant issue affecting physicians and the healthcare system is malpractice. In the latter half of the 20th century, there was a major change in the attitude of the public towards the medical profession. People were made aware of the huge advances in medical technology, because health problems increasingly tended to attract media interest and wide publicity. Medicine is a victim of its own success in this respect, and people are now led to expect the latest techniques and perfect outcomes on all occasions. This burst of technology and hyper-specialization in many fields of medicine means that each malpractice claim is transformed into a scientific challenge, requiring specific preparation in analysis and judgment of the clinical case in question. The role of legal medicine becomes more and more peculiar in this judicial setting, often giving rise to erroneous interpretations and hasty scientific verdicts, but guidelines on the methodology of ascertainments and criteria of evaluation are lacking all over the world.The aim of this volume is to clarify the steps required for sequential in-depth analysis of events and consequences of medical actions, in order to verify whether, in the presence of damage, errors or non-observance of rules of conduct by health personnel exist, and which causal values and links of their hypothetical misconduct are involved.
Radiology Illustrated: Hepatobiliary and Pancreatic Radiology
by Byung Ihn ChoiRadiology Illustrated: Hepatobiliary and Pancreatic Radiology is the first of two volumes that will serve as a clear, practical guide to the diagnostic imaging of abdominal diseases. This volume, devoted to diseases of the liver, biliary tree, gallbladder, pancreas, and spleen, covers congenital disorders, vascular diseases, benign and malignant tumors, and infectious conditions. Liver transplantation, evaluation of the therapeutic response of hepatocellular carcinoma, trauma, and post-treatment complications are also addressed. The book presents approximately 560 cases with more than 2100 carefully selected and categorized illustrations, along with key text messages and tables, that will allow the reader easily to recall the relevant images as an aid to differential diagnosis. At the end of each text message, key points are summarized to facilitate rapid review and learning. In addition, brief descriptions of each clinical problem are provided, followed by both common and uncommon case studies that illustrate the role of different imaging modalities, such as ultrasound, radiography, CT, and MRI.
Fair Revenue Sharing Mechanisms for Strategic Passenger Airline Alliances
by Demet ÇetinerA major problem arising in airline alliances is to design allocation mechanisms determining how the revenue of a product should be shared among the airlines. The nucleolus is a concept of cooperative game theory that provides solutions for allocating the cost or benefit of a cooperation. This work provides fair revenue proportions for the airline alliances based on the nucleolus, which assumes a centralized decision making system. The proposed mechanism is used as a benchmark to evaluate the fairness of the revenue sharing mechanisms, where the alliance partners behave selfishly. Additionally, a new selfish revenue allocation rule is developed that improves the performance of the existing methods.
Copyright Collective Administration in Nigeria: Lessons for Africa (SpringerBriefs in Law)
by Olukunle OlaThis work explores the operation and regulation of copyright collective management in Nigeria. The nexus between creativity and copyright and how creativity has played a pivotal role in development is explained. The need to balance the interests of authors and users is discussed and the societies representing the interest of copyright owners are illustrated. Further, Nigeria's legal framework for collective management is enunciated from a pre-independence and post-independence perspective. In the course of this regulatory challenges encountered in the administration of collective management organizations, steps so far taken to address the problems, legislative reforms and judicial decisions are discussed. A path to the new regime is chartered. The South African Copyright collective management system is explored and a comparison between the Nigerian and South African system is made. Thereby the need for supervisory and regulatory agencies of government is shown to seek the national interest regarding the collective administration of copyright and related rights. Then, suggestions for improvement and lessons for Africa are provided.
Has Man a Future?: Dialogues with the Last Confucian
by Shu Ming Liang Guy S. AlittoLiang Shu-ming (October 18, 1893 - June 23, 1988), was a legendary philosopher, teacher, and leader in the Rural Reconstruction Movement in the late Qing Dynasty and early Republican eras of Chinese history. Liang was also one of the early representatives of modern Neo-Confucianism. Guy S. Alitto, associate Professor in the Department of East Asian Languages and Civilizations (EALC) at The University of Chicago, is author of, among other things, The Last Confucian: Liang Shu-ming and the Chinese Dilemma of Modernity, and is one of the most active and influential Sinologists in America. In 1980 and again in 1984, at Liang Shu-ming's invitation, he conducted a series of interviews with Liang in Liang's Beijing home. This book of dialogues between the American sinologist and "The Last Confucian", Liang Shu-ming, gives a chronological account of the conversations that took place in Beijing in 1980. In these conversations, they discussed the cultural characteristics of Confucianism, Buddhism, Daoism, and their representative figures, and reviewed the important activities of Mr. Liang's life, along with Liang's reflection on his contact with many famous people in the cultural and political realms - Li Dazhao, Chen Duxiu, Mao Zedong, Zhou Enlai, Chiang Kai-shek, Kang Youwei, Hu Shi, etc. Rich in content, these conversations serve as important reference material for understanding and studying Mr. Liang Shuming's thoughts and activities as well as the social and historical events of modern China.
New Perspectives in Regeneration
by David L. Stocum Ellen Heber-KatzRegeneration, the homeostatic ability to maintain tissue structure in the face of normal cell turnover or loss of tissue damaged by trauma or disease, is an essential developmental process that continues throughout life. As recently as a decade ago, any serious discussion of the possibility of regeneration becoming a practical medical tool in the near future had the air of science fiction or over-optimistic speculation. The term "regenerative medicine" was certainly on many lips but few actually expected to soon see it applied in a clinical setting. A tidal wave of discovery has changed that and investigating the cellular mechanisms of natural regeneration has become one of the hottest topics in developmental biology and biomedicine in general. Many researchers entering the field find that the regeneration literature is still quite diffuse perhaps owing to the disparate biological systems that have been the object of study including hydra, planaria, newts, axolotls and more recently several mouse strains. The volume editors believe that an attempt to organize or systematize the literature is long overdue. In this volume, respected experts highlight the latest findings in vertebrate (including mammals) wound healing and regeneration. They present eleven reviews that cover a wide range of topics, from wound repair and its relationship to regeneration, through systems including lenticular, neural, and musculoskeletal tissues and limbs, to epigenetics and the role of the cell cycle. Nuclear reprogramming and cellular plasticity, which open the door for potential regenerative medical therapies for injury and degenerative disease, are recurring themes throughout the book. We are all now part of the regeneration revolution.
Resonance Effects of Excitons and Electrons
by Dieter Suter Ion GeruThis book presents the various types of resonance effects on excitons, biexcitons and the local electronic centers (LEC) in solids, such as paramagnetic and paraelectric resonances on excitons, exciton acoustic resonance at intra- and interband transitions, radio-optical double resonance on excitons, hole-nuclear double resonance on localized biexcitons, ENDOR and acoustic ENDOR on LEC. The criteria for the generation of coherent photons, phonons and magnons by excitons are explained. The interactions of excitons and biexcitons with paramagnetic centers and nuclear spins, the indirect interaction between the PC through a field of excitons as well as the quasienergy spectrum of excitons and spin systems are discussed. It is proved that the interaction of paramagnetic centers with excitons increases the spin relaxation rate of paramagnetic centers in comparison with the case of their interaction with free carriers. The giant magneto-optical effects in semi-magnetic semiconductors are theoretically interpreted. In recent years, a new perspective has been added to these systems and their interactions: They can be used for storing and processing information in the form of quantum bits (qubits), the building blocks of quantum computers. The basics of this emerging technology are explained and examples of demonstration-type quantum computers based on localized spins in solids are discussed.
On the Frontiers of Climate and Environmental Change
by Ole Bruun Thorkil CasseThis book is intended to fill a gap in climate-change literature by providing a comprehensive regional study and identifying the overall adaptation challenges in a real-life context. The way in which possible climate impacts interact with a range of other challenges in agriculture, forestry, disaster planning, health care, general economic development, and common livelihoods are presented, and it is argued that greater realism and broader vision are needed in order to address the climate challenge. For instance, unsuitable land- use changes in both coastal and highland regions may increase the vulnerability of rural people, many of whom are already living on the fringes. The author(s) also state(s) that, depending on context, it may be pertinent to address short-term and unsustainable resource use, irregularities in local land management, ineffective governance and social inequality, which are all likely to aggravate the impact of external climate and weather. Not least, it is imperative to integrate general environmental management with any climate-change adaptation effort.