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Atlas of the Mammalian Ovary: Morphological Dynamics and Potential Role of Innate Immunity
by Katharina Spanel-BorowskiIn the era of molecular biology, an atlas that allows a rapid understanding of the complexity of ovarian processes is urgently needed. In this book, the author draws upon her own research, conducted over the past three decades, to provide a unique compilation of high-quality illustrations that offer illuminating insights in a readily accessible form. The ovarian follicles, the corpus luteum, and the interstitial cortex are presented as precisely controlled homeostatic compartments. Physiologic cell death forms and leukocyte subtypes are clearly depicted, and the various steps in the ovulatory process are demonstrated in detail. Further topics addressed include the microvascular bed, the plasticity of intraovarian nerves as part of the remodelling processes in the polycystic and the menopausal ovary, and the role of cytokeratin-positive cells as messengers of innate immunity. This atlas will be a fascinating and informative resource for both trainees and more experienced professionals.
Numerical Analysis of Heat and Mass Transfer in Porous Media
by J.M.P.Q. Delgado Antonio Gilson Lima Marta Vázquez SilvaThe purpose of 'Numerical Analysis of Heat and Mass Transfer in Porous Media' is to provide a collection of recent contributions in the field of computational heat and mass transfer in porous media. The main benefit of the book is that it discusses the majority of the topics related to numerical transport phenomenon in engineering (including state-of-the-art and applications) and presents some of the most important theoretical and computational developments in porous media and transport phenomenon domain, providing a self-contained major reference that is appealing to both the scientists, researchers and the engineers. At the same time, these topics encounter of a variety of scientific and engineering disciplines, such as chemical, civil, agricultural, mechanical engineering, etc. The book is divided in several chapters that intend to be a resume of the current state of knowledge for benefit of professional colleagues.
Peri-urban futures: Scenarios and models for land use change in Europe
by Simon Bell Kjell Nilsson Stephan Pauleit Carmen Aalbers Thomas A. Sick NielsenPresently, peri-urbanisation is one of the most pervasive processes of land use change in Europe with strong impacts on both the environment and quality of life. It is a matter of great urgency to determine strategies and tools in support of sustainable development. The book synthesizes the results of PLUREL, a large European Commission funded research project (2007-2010). Tools and strategies of PLUREL address main challenges of managing land use in peri-urban areas. These results are presented and illustrated by means of 7 case studies which are at the core of the book. This volume presents a novel, future oriented approach to the planning and management of peri-urban areas with a main focus on scenarios and sustainability impact analysis. The research is unique in that it focuses on the future by linking quantitative scenario modeling and sustainability impact analysis with qualitative and in-depth analysis of regional strategies, as well as including a study at European level with case study work also involving a Chinese case study.
Outer Membrane Vesicles of Bacteria
by Keya Chaudhuri S. N. ChatterjeeThis book provides a detailed account of the physico-chemical properties and biological functions of the outer membrane vesicles (OMVs) of different pathogenic and non-pathogenic Gram-negative bacteria. It also includes an authentic record of the first systematic study that discovered the mechanism of OMV formation by a pathogen, Vibrio cholerae, and proposed that the process represented a novel secretory activity of bacteria. Furthermore, the authors present clinical and laboratory data on the use of OMVs as immunogens, as effective and licensed vaccines against Neisseria meningitidis serogroup B infections and on the development of more effective vaccines against other human and animal pathogens including Vibrio cholerae. This volume thus bears witness to the emerging revolution in the field of vaccines against pathogens and closes with a discussion of open questions and future research on OMVs.
Wind Energy Meteorology
by Stefan EmeisThis book is intended to give an introduction into the meteorological boundary conditions for power generation from the wind, onshore and offshore. It is to provide reliable meteorological information for the planning and running of this important kind of renewable energy. This includes the derivation of wind laws and wind profile descriptions, especially those above the logarithmic surface layer. Winds over complex terrain and nocturnal low-level jets are considered as well. A special chapter is devoted to the efficiency of large wind parks and their wakes.
Inflammatory Diseases of the Brain
by Stefan HähnelThis second, updated edition of Inflammatory Diseases of the Brain provides a comprehensive overview of the field from a neuroradiological point of view. In order to ensure a standardized approach throughout, each disease-oriented chapter is again subdivided into three principal sections: epidemiology, clinical presentation, and therapy; imaging; and differential diagnosis. A separate chapter addresses technical and methodological issues and imaging protocols. An important focus of the book is the current role of advanced MR imaging techniques, such as diffusion and perfusion MRI and MR spectroscopy, in the differentiation of inflammatory and other brain diseases. All of the authors are recognized experts, and the numerous high-quality and informative illustrations include some not contained in the first edition. This book will be of great value not only to neuroradiologists but also to neurologists, neuropediatricians, and general radiologists.
Coarse-Grained Modelling of DNA and DNA Self-Assembly (Springer Theses)
by Thomas E. OuldridgeThis thesis presents a novel coarse-grained model of DNA, in which bases are represented as rigid nucleotides. The model is shown to quantitatively reproduce many phenomena, including elastic properties of the double-stranded state, hairpin formation in single strands and hybridization of pairs of strands to form duplexes, the first time such a wide range of properties has been captured by a coarse-grained model. The scope and potential of the model is demonstrated by simulating DNA tweezers, an iconic nanodevice, and a two-footed DNA walker -- the first time that coarse-grained modelling has been applied to dynamic DNA nanotechnology.
Grundzüge der Wirtschaftsinformatik
by Arnold Picot Thomas Hess Wolfgang König Matthias Schumann Peter Mertens Freimut BodendorfIm Standardwerk der Wirtschaftsinformatik sind die Grundlagen strukturiert und kompakt aufbereitet: von Rechnerarchitekturen über Einsatzpotenziale bis hin zu Berufsfeldern der Wirtschaftsinformatik. Ausgehend von der Arbeitsweise des PCs, der Einbettung von Rechnern in Netzwerke sowie der Integration der verfügbaren Dienste, werden die Grundlagen des Datenmanagements sowie die Unterstützung betrieblicher Funktionen und Prozesse durch Informationsverarbeitung erläutert. Für die 11. Auflage wurden die Inhalte vollständig überarbeitetet.
Grundzüge der Wirtschaftsinformatik (Springer-Lehrbuch)
by Arnold Picot Thomas Hess Wolfgang König Matthias Schumann Peter Mertens Freimut BodendorfIm Standardwerk der Wirtschaftsinformatik sind die Grundlagen strukturiert und kompakt aufbereitet: von Rechnerarchitekturen über Einsatzpotenziale bis hin zu Berufsfeldern der Wirtschaftsinformatik. Ausgehend von der Arbeitsweise des PCs, der Einbettung von Rechnern in Netzwerke sowie der Integration der verfügbaren Dienste, werden die Grundlagen des Datenmanagements sowie die Unterstützung betrieblicher Funktionen und Prozesse durch Informationsverarbeitung erläutert. Für die 11. Auflage wurden die Inhalte vollständig überarbeitetet.
Finance – Fundamental Problems and Solutions
by Zhiqiang ZhangAs indicated by the title, this book focuses on fundamental problems in finance: a logical dilemma in valuation, stock valuation methods/models, risk valuation, and optimal capital structure. It presents an innovative approach to logic and quantitative reasoning (without advanced mathematics) that delivers valuable results ---- convincing solutions to these problems. Readers in finance will definitely be interested in these solutions as well as the methods. In fact, these fundamental problems are essential in the field of finance, and they have remained unsolved (or partly unsolved) for decades. The solutions offered in this book are all sound in theory and feasible in practice, and will hopefully benefit both theoretic al research and practical decision-making.
3D ohne 3D-Brille: Handbuch der Autostereoskopie (X.media.press)
by Armin GrasnickSeit dem kommerziellen Erfolg des 3D-Blockbusters ,,Avatar" im Jahr 2009 kommen immer mehr 3D-Filme und 3D-Fernseher auf den Markt. Mittlerweile gibt es Autostereoskopie-Verfahren, bei denen Zuschauer keine 3D-Brille mehr benötigen. In dem Band werden die derzeit verfügbaren Technologien der Autostereoskopie, ihre Funktionsweise, Anwendung und Limitierung allgemeinverständlich beschrieben. Zu jeder Technologie liefert der Band Anleitungen und Beispiele für die Erstellung von 3D-Inhalten. Alle Tools sind auf der begleitenden Internetseite verfügbar.
CAFM-Handbuch: IT im Facility Management erfolgreich einsetzen
by Michael MayDer effektive Einsatz der Informationstechnologie im Facility Management stellt eine große Herausforderung dar. In dem Handbuch finden Nutzer erstmals systematisch alle Aspekte gebündelt, die bei der Einführung einer Computer-Aided-Facility-Management-Software zu beachten sind: Bedeutung, Einsatzbereiche und Prozesse sowie neue Modelle zur Wirtschaftlichkeitsbetrachtung werden erörtert. Neu in der 3. Auflage: aktuelle Entwicklungen wie Webservices und moderne Integrationsansätze. Der Band bietet viele Praxisbeispiele und Tipps.
Mesoscopic Quantum Hall Effect
by Ivan LevkivskyiIn recent years, remarkable progress in the fabrication of novel mesoscopic devices has produced a revival of interest in quantum Hall physics. New types of measurements, more precise and efficient than ever, have made it possible to focus closely on the electronic properties of quantum Hall edge states. This is achieved by applying charge and heat currents at mesoscopic length scales, attaching metallic gates and Ohmic contacts, and splitting edge channels with the help of quantum point contacts. The experiments reveal fascinating new phenomena, such as the interference, statistics, and topological phase shifts of fractionally charged quasi-particles, strong interaction and correlation effects, and phase transitions induced by non-Gaussian fluctuations. The thesis discusses some puzzling results of these experiments and presents a coherent picture of mesoscopic effects in quantum Hall systems, which accounts for integer and fractional filling factors and ranges from microscopic theory to effective models, and covers both equilibrium and non-equilibrium phenomena.
Self-Organized Arrays of Gold Nanoparticles
by Luca AnghinolfiThis thesis addresses the fabrication and investigation of the optical response of gold nanoparticle arrays supported on insulating LiF(110) nanopatterned substrates. Motivated by the discovery of the intriguing effects that arise when electromagnetic radiation interacts with metallic nanostructures, the thesis focuses on the application of bottom-up approaches to the fabrication of extended-area plasmonic nanostructures, and the optimization of their optical response. By developing a sophisticated effective-medium model and comparing the experimental findings with model calculations, the author explores the role of the interparticle electromagnetic coupling and array dimensionality on the collective plasmonic behavior of the array, giving insights into the physical mechanisms governing the optical response.
Total Addiction
by Kate RussoSeeing a total solar eclipse is often described as a once-in-a-lifetime experience. However, for many who have experienced totality, once-in-a-lifetime is simply not enough. They want more, and are willing to go to great lengths often at great expense to repeat the experience. What is it like to experience totality? What is it about the experience that motivates these eclipse chasers? Is there an eclipse chaser personality? Can eclipse chasing actually be described as an addiction? This book describes the people who dedicate their lives to chasing their dream.
Fundamentals of Inertial Navigation, Satellite-based Positioning and their Integration
by Jacques Georgy Tashfeen B. Karamat Aboelmagd NoureldinFundamentals of Inertial Navigation, Satellite-based Positioning and their Integration is an introduction to the field of Integrated Navigation Systems. It serves as an excellent reference for working engineers as well as textbook for beginners and students new to the area. The book is easy to read and understand with minimum background knowledge. The authors explain the derivations in great detail. The intermediate steps are thoroughly explained so that a beginner can easily follow the material. The book shows a step-by-step implementation of navigation algorithms and provides all the necessary details. It provides detailed illustrations for an easy comprehension. The book also demonstrates real field experiments and in-vehicle road test results with professional discussions and analysis. This work is unique in discussing the different INS/GPS integration schemes in an easy to understand and straightforward way. Those schemes include loosely vs tightly coupled, open loop vs closed loop, and many more.
Nucleic Acid Drugs
by Akira MurakamiNew Antisense Strategies: Chemical Synthesis of RNA Oligomers, by Junichi Yano und Gerald E. Smyth Development and Modification of Decoy Oligodeoxynucleotides for Clinical Application, by Mariana Kiomy Osako, Hironori Nakagami und Ryuichi Morishita Modulation of Endosomal Toll-Like Receptor-Mediated Immune Responses by Synthetic Oligonucleotides, by Ekambar R. Kandimalla und Sudhir Agrawal Delivery of Nucleic Acid Drugs, by Yan Lee und Kazunori Kataoka Aptamer: Biology to Applications, by Yoshikazu Nakamura Development and Clinical Applications of Nucleic Acid Therapeutics, by Veenu Aishwarya, Anna Kalota und Alan M. Gewirtz
Cleaner Combustion and Sustainable World
by Bo Zhao Haiying QiCleaner Combustion and Sustainable World is the proceedings of the 7th International Symposium on Coal Combustion which has a significant international influence. It concerns basic research on coal combustion and clean utilization, techniques and equipments of pulverized coal combustion, techniques and equipments of fluidized bed combustion, basic research and techniques of emission control, basic research and application techniques of carbon capture and storage (CCS), etc. Professor Haiying Qi and Bo Zhao both work at the Tsinghua University, China
Multi-scale Dynamical Processes in Space and Astrophysical Plasmas
by Manfred P. Leubner Zoltán VörösMagnetized plasmas in the universe exhibit complex dynamical behavior over a huge range of scales. The fundamental mechanisms of energy transport, redistribution and conversion occur at multiple scales. The driving mechanisms often include energy accumulation, free-energy-excited relaxation processes, dissipation and self-organization. The plasma processes associated with energy conversion, transport and self-organization, such as magnetic reconnection, instabilities, linear and nonlinear waves, wave-particle interactions, dynamo processes, turbulence, heating, diffusion and convection represent fundamental physical effects. They demonstrate similar dynamical behavior in near-Earth space, on the Sun, in the heliosphere and in astrophysical environments. 'Multi-scale Dynamical Processes in Space and Astrophysical Plasmas' presents the proceedings of the International Astrophysics Forum Alpbach 2011. The contributions discuss the latest advances in the exploration of dynamical behavior in space plasmas environments, including comprehensive approaches to theoretical, experimental and numerical aspects. The book will appeal to researchers and students in the fields of physics, space and astrophysics, solar physics, geophysics and planetary science.
Evolutionary Biology: Mechanisms and Trends
by Pierre PontarottiThe annual Evolutionary Biology Meetings in Marseilles serve to gather leading evolutionary biologists and other scientists using evolutionary biology concepts, e.g. for medical research. The aims of these meetings are to promote the exchange of ideas and to encourage interdisciplinary collaborations. This book collects 19 selected contributions presented at the 15th meeting, which took place in September 2011. It starts with a description of the life and work of J.B.S. Haldane, a remarkable evolutionary biologist of the 20th century. The remaining chapters are grouped under the following three themes: · New Concepts in Evolutionary Biology · Macroevolution: Mechanisms and Trends · Genome Evolution Offering an up-to-date overview of recent results in the field of evolutionary biology, this book is an invaluable source of information for scientists, teachers and advanced students.
Enabling Flexibility in Process-Aware Information Systems: Challenges, Methods, Technologies
by Barbara Weber Manfred ReichertIn today's dynamic business world, the success of a company increasingly depends on its ability to react to changes in its environment in a quick and flexible way. Companies have therefore identified process agility as a competitive advantage to address business trends like increasing product and service variability or faster time to market, and to ensure business IT alignment. Along this trend, a new generation of information systems has emerged--so-called process-aware information systems (PAIS), like workflow management systems, case handling tools, and service orchestration engines. With this book, Reichert and Weber address these flexibility needs and provide an overview of PAIS with a strong focus on methods and technologies fostering flexibility for all phases of the process lifecycle (i.e., modeling, configuration, execution and evolution). Their presentation is divided into six parts. Part I starts with an introduction of fundamental PAIS concepts and establishes the context of process flexibility in the light of practical scenarios. Part II focuses on flexibility support for pre-specified processes, the currently predominant paradigm in the field of business process management (BPM). Part III details flexibility support for loosely specified processes, which only partially specify the process model at build-time, while decisions regarding the exact specification of certain model parts are deferred to the run-time. Part IV deals with user- and data-driven processes, which aim at a tight integration of processes and data, and hence enable an increased flexibility compared to traditional PAIS. Part V introduces existing technologies and systems for the realization of a flexible PAIS. Finally, Part VI summarizes the main ideas of this book and gives an outlook on advanced flexibility issues. The book's target groups include researchers, PhD students and Master students in the field of information systems. After reading the book, they will better understand PAIS flexibility aspects. To support the easy use as a textbook, a series of exercises is provided at the end of each chapter and slides and further teaching material are available on the book's web site www.flexible-processes.com. Professionals specializing in business process management (BPM) who want to obtain a good understanding of flexibility challenges in BPM and state-of-the-art solutions will also benefit from the presentations of open source as well as commercial process management systems and related practical scenarios.
Mouse Development
by Jacek Z. KubiakThe mouse is a perfect model organism to study mammalian, and thus indirectly also human, embryology. Most scientific achievements that have had an important impact on the understanding of basic mechanisms governing embryo development in humans, originated from mouse embryology. Stem cell research, which now offers the promise of regenerative medicine, began with the isolation and culture of mouse embryonic stem cells by Martin Evans (who received the Nobel Prize in medicine in 2007 for this achievement) and Matthew Kaufman. This book provides an overview of mouse development, spanning from oocytes before fertilization to the state-of-the-art description of embryonic and adult stem cells. The chapters, written by the leading specialists in the field, deal with the most recent discoveries in this extremely fast-developing area of research.
Analytical Imaging Techniques for Soft Matter Characterization (Engineering Materials)
by Vikas Mittal Nadejda B. MatskoThe book aims to describe the microscopic characterization of the soft matter in the light of new advances acquired in the science of microscopy techniques like AFM; SEM; TEM etc. It does not focus on the traditional information on the microscopy methods as well as systems already present in different books, but intends to answer more fundamental questions associated with commercially important systems by using new advances in microscopy. Such questions are generally not answered by other techniques. The contents of the book also reflect this as the chapters are not based on describing only material systems, but are based on the answering the problems or questions arising in their characterization. Both qualitative as well as quantitative analysis using such microscopic techniques is discussed. Moreover, efforts have been made to provide a broader reach as discussions on both polymers as well as biological matter have been included as different sections. Such a text with comprehensive overview of the various characterization possibilities using microscopy methods can serve as a valuable reference for microscopy experts as well as non-experts alike
The Dual Nature of Life
by Gennadiy ZhegunovLife is a diverse and ubiquitous phenomenon on Earth, characterized by fundamental features distinguishing living bodies from nonliving material. Yet it is also so complex that it has long defied precise definition. This book from a seasoned biologist offers new insights into the nature of life by illuminating a fascinating architecture of dualities inherent in its existence and propagation. Life is connected with individual living beings, yet it is also a collective and inherently global phenomenon of the material world. It embodies a dual existence of cycles of phenotypic life, and their unseen driver -- an uninterrupted march of genetic information whose collective immortality is guaranteed by individual mortality. Although evolution propagates and tunes species of organisms, the beings produced can be regarded merely as tools for the survival and cloning of genomes written in an unchanging code. What are the physical versus informational bases and driving forces of life, and how do they unite as an integrated system? What does time mean for individuals, life on the global scale, and the underlying information? This accessible examination of principles and evidence shows that a network of dualities lies at the heart of biological puzzles that have engaged the human mind for millennia.
Groundwater in Ethiopia
by Seifu KebedeThis book provides a comprehensive description of groundwater resources in Ethiopia and its various dimensions (groundwater as resource, environmental functions, and socioeconomics). The prevailing knowledge of groundwater resources in Ethiopia (or elsewhere in Sub Saharan Africa) was based on geological and stratigraphic framework known nearly four decades ago (mainly 1960's and 70's). Thanks to the substantial geoscientific research since the 70's a new set of relevant geological/stratigrahpic data has been created that helps to re-define our understanding of groundwater resources in Africa as a whole and in Ethiopia in particular: a) For the first time the basement aquifer of Ethiopia has been described hydrogeologically based on genesis of regoliths (deep weathering and striping history); clear regional difference in groundwater potential is shown for the first time; comparative accounty has been given regarding groundwater occurrence in the generally low grade basement rocks of Ethiopia (Arabian Nubian shield) and high grade basement rocks of the rest of Africa. b) For the first time groundwater occurrence in multilayred sedimentary rocks account for spatial variation in degree of karstification; deformation history, and stratigraphy. c) The vast volcanic aquifers of Ethiopia which have previously classified based on their ages are now reclassified based on age, morphology (eg. groundwater in plateau volcanics, groundwater in shield volcanics) and aquifer structure. d) The loose alluvio lacustrine sediments which were known as least extensive in previous works based on areal cover are in fact shown to host the most voluminous groundwater resources in Ethiopia. These aquifers have now been described based on their geomorphology, extent, and genesis. The aim of this book is to use these newly created knowledge to redefine the understanding of groundwater resources in Ethiopia.