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Heat Transfer in Multi-Phase Materials
by Andreas Öchsner Graeme E. MurchThis book provides a profound understanding, which physical processes and mechanisms cause the heat transfer in composite and cellular materials. It shows models for all important classes of composite materials and introduces into the latest advances. In three parts, the book covers Composite Materials (Part A), Porous and Cellular Materials (Part B) and the appearance of a conjoint solid phase and fluid aggregate (Part C).
Python 3 - Intensivkurs
by Mark Pilgrim Florian WollenscheinPython ist eine vollwertige Programmiersprache, mit der sich auch größere Anwendungen entwickeln lassen. In den letzten Jahren hat sie an Beliebtheit gewonnen, und mit Python 3 steht eine stark erweiterte Version zur Verfügung. In dem Band werden die Werkzeuge und Programmiermöglichkeiten praxisorientiert vorgestellt. Jedes Kapitel beginnt mit einem vollwertigen, lauffähigen Codebeispiel, das jeweils ausführlich analysiert wird. Im Vordergrund stehen die unmittelbare praktische Anwendung und die Realisierung von Projekten mit Python 3.
Immobilien-Projektentwicklung
by Torsten HeldFür Unternehmen der Immobilienwirtschaft stellt die volatile Markt- und Wettbewerbssituation eine große strategische und strukturelle Herausforderung dar. Eine strategische Planung sowie die Verbesserung von Organisation und Abläufen in der Immobilienwirtschaft gewinnen daher zunehmend an Bedeutung. Der Band setzt hier an und konzentriert sich auf die Immobilien-Projektentwicklung, welche am Anfang des Lebenszyklus einer Immobilie steht und deswegen einen enormen Stellenwert für den ökonomischen Erfolg besitzt.
The Strategic CFO
by Lutz Firnkorn Ervin Schellenberg Ulrich Hommel Michael FabichThe role of the Chief Financial Officer (CFO) has substantially changed in a world characterized by globalized financial markets and truly global products. The accelerated development of new technologies, products, and markets has led to an increasingly dynamic and uncertain competitive situation. The book demonstrates and discusses the impact of this changing corporate environment on the role and responsibilities of the CFO. A more holistic view that integrates business and financial decisions is required in order to manage these challenges of globalization. The book shows how the CFO can adopt and implement this management approach and thus play a vital role in the firm's value creation.
Eine Entdeckung von ganz außerordentlicher Tragweite
by Karl Von MeyennMit der Bekanntgabe seiner Wellenmechanik Anfang des Jahres 1926 eröffnetet Erwin Schrödinger viele neue physikalische Perspektiven. Auch heute noch bildet die Schrödingergleichung die Grundlage der gesamten Mikrophysik und ihrer Anwendungen. Die Entstehungsgeschichte dieser Entdeckung beleuchtet der Band anhand von 300 Briefen, die Schrödinger mit Zeitgenossen, darunter Albert Einstein, ausgetauscht hat. Die Briefe hat der Herausgeber mit Anmerkungen und Kommentaren versehen und in ihren wissenschaftlichen und historischen Kontext gestellt.
Organized Crime Legislation in the European Union
by Francesco CalderoniJust a few months after the entry into force of the EU Framework Decision on the fight against organized crime, this book provides an unprecedented analysis of the national and European legislation on organized crime. The book provides a critical examination of the European policies and legal instruments to promote the harmonization and approximation of criminal law in this field (including the United Nations Convention on Transnational Organized Crime). The current level of harmonization among EU Member States and the approximation to the standards of the new Framework Decision are discussed in detail, with the help of tables, graphs and maps. The results highlight the problems surrounding the international legal instruments and the inconsistencies of the national approaches to combating organized crime.
Selected Problems in Physical Chemistry
by Predrag-Peter IlichThis book is a collection of 50 original problems in physical chemistry including several living systems. Each problem is accompanied by a detailed step-by-step solution, organized as strategy, assumptions, approximations, numerical calculation and interpretation. Solutions to the key problems (e.g. thermal equilibration, ligand-receptor interaction, aminoacid zwitterions, HOMO-LUMO gap) are accompanied by simple introductory explanations. In addition, informal notes are provided on difficult concepts, for example: entropy, reaction activation barrier, wave mechanics. Schemes, diagrams and structural formulas accompany most solutions and explanations. Thus, this textbook may serve as a self-tutorial for undergraduate students in physical chemistry, biophysics, biochemistry, and medicinal chemistry.
Kompendium semantische Netze
by Klaus ReichenbergerSemantische Technologien werden als die zukünftige Form menschlichen Wissens gehandelt. Gleichzeitig haftet ihnen etwas von einer Geheimwissenschaft an. Dieses Kompendium bietet eine - auch für Einsteiger verständliche - Einführung in das Thema. Es präsentiert verschiedene semantische Techniken, von automatischen Text-Mining-Verfahren bis hin zu komplexen Ontologien. Leser werden anhand von Beispielen in die Lage versetzt, selbst zu beurteilen, was semantische Technologien leisten. Im praktischen Teil lernen sie, semantische Netze zu modellieren.
Innovative Quick Response Programs in Logistics and Supply Chain Management
by T. C. Cheng Tsan-Ming ChoiQuick Response (QR) policy is a market-driven business strategy in which supply chain members work together to react quickly to volatile market demand. Nowadays, with advances in information technologies (such as RFID and ERP systems), new challenges and opportunities arise for the application of QR. This handbook explores QR extensively with a view to discovering innovative QR measures that can help tackle the observed and emerging challenges. The book is organized into four parts, which include chapters on analytical modeling and analyses, information technologies, cases, reviews, and applications. This handbook provides new analytical and empirical results with valuable insights, which will not only help supply chain agents to better understand the latest applications of QR in business, but also help practitioners and researchers to know how to improve the effectiveness of QR using innovative methods.
IGFs:Local Repair and Survival Factors Throughout Life Span
by David Clemmons Iain C.A.F. RobinsonInsulin-like growth factors (IGFs), their binding proteins and their receptors play important roles in regulating growth, metabolism, proliferation and survival for many cells and tissues throughout lifespan in humans and other species. Circulating IGF1 is known to be an endocrine regulator, with metabolic effects related to, and partly convergent with, insulin signalling. IGF1 also mediates many of the growth promoting effects of GH, and there is an ongoing debate as to the relative contributions of endocrine-, vs locally-derived IGF1 for systemic growth. More recently however, it has become clear that IGFs may be key local growth and cellular survival factors for many different tissues, active from early in embryonic development, essential for normal maturation and growth during foetal life. IGFs continue to play important roles throughout adult life in many diverse processes such as tissue repair, cellular proliferation, tissue remodelling and metabolic regulation. IGF systems are tightly regulated; orderly control of cellular repair and metabolism is central to healthy ageing, whilst uncontrolled proliferation can lead to cancer.
Diabetes, Insulin and Alzheimer's Disease
by Suzanne CraftThis volume brings together experts from basic and clinical science to provide a broad survey of the role of insulin in the brain, and to discuss the mechanisms through which insulin dysregulation contributes to the development of cognitive impairment and late-life neurodegenerative disease. Each author has greatly furthered our understanding of the relationships among insulin, diabetes, and Alzheimer's disease, moving us far beyond the belief that the brain is an insulin-insensitive organ. Given the recent pandemic of conditions associated with insulin resistance, it is imperative that we achieve a comprehensive knowledge of the mechanisms through which insulin resistance affects brain function in order to develop therapeutic strategies to address these effects.
Macro Roles for MicroRNAs in the Life and Death of Neurons
by Bart De StrooperThe discovery of microRNAs has revealed an unexpected and spectacular additional level of fine tuning of the genome and how genes are used again and again in different combinations to generate the complexity that underlies for instance the brain. Since the initial studies performed in C.elegans, we gave gone a far way to begin to understand how microRNA pathways can have an impact on health and disease in human. Although microRNAs are abundantly expressed in the brain, relatively little is known about the multiple functions of these RNA molecules in the nervous system. Nevertheless, we know already that microRNA pathways play major roles in the proliferation, differentiation, function and maintenance of neuronal cells. Several intriguing studies have linked microRNAs as major regulators of the neuronal phenotype, and have implicated specific microRNAs in the regulation of synapse formation and plasticity. Dysfunction of microRNA pathways is also slowly emerging as a potential important contributor to the pathogenesis of major neurodegenerative disorders such as Alzheimer's disease and Parkinson's disease. These novel insights appear to be particular promising for the understanding of the very frequent and badly understood sporadic forms of these diseases as compared to the genetic forms. Thus, the better understanding of the implications of this novel field of molecular biology is crucial for the broad area of neurosciences, from the fundamental aspects to the clinic, and from novel diagnostic to potentially therapeutic applications for severe neurological and maybe psychiatric diseases.
Test-Driven Development
by Lech MadeyskiAgile methods are gaining more and more interest both in industry and in research. Many industries are transforming their way of working from traditional waterfall projects with long duration to more incremental, iterative and agile practices. At the same time, the need to evaluate and to obtain evidence for different processes, methods and tools has been emphasized. Lech Madeyski offers the first in-depth evaluation of agile methods. He presents in detail the results of three different experiments, including concrete examples of how to conduct statistical analysis with meta analysis or the SPSS package, using as evaluation indicators the number of acceptance tests passed (overall and per hour) and design complexity metrics. The book is appropriate for graduate students, researchers and advanced professionals in software engineering. It proves the real benefits of agile software development, provides readers with in-depth insights into experimental methods in the context of agile development, and discusses various validity threats in empirical studies.
Drowning
by Joost J.L.M. BierensSince the first edition of the Handbook on Drowning in 2005, many epidemiological data have confirmed the burden of drowning in several parts of the world. Studies have increased the understanding of effective drowning prevention strategies, rescue techniques and treatment options. Much has been learned about submersion and immersion hypothermia, SCUBA-diving injuries, the life-saving preparations of water-related disasters and how to deal with forensic investigations. In this updated second edition, experts from around the world provide a complete overview of current research data, consensus statements and expert opinions. The book Drowning provides evidence-based practical information and has a unique informative value for various groups with tasks, duties and responsibilities in this domain. In addition, the book may be an inspiration for future networks and research initiatives.
Production and Inventory Management with Substitutions
by J. Christian LangThis book addresses production and inventory management problems where products can be replaced by specified substitutes. Depending on the considered application, substitutions can potentially improve the service level, reduce required safety stocks and total setup costs and times, utilize cost variations of input products, and reduce the amount of wastage. The main focus is the development of graphical modeling approaches for substitution options and of production planning models based on these approaches using mathematical programming. In addition to single-level dynamic lot-sizing models with substitutions, models for multi-level production systems with flexible bills-of-materials and recipes are devised. Also, a simulation-based optimization approach for a multi-location inventory system with substitutions is developed.
99mTc-Sestamibi: Clinical Applications
by Hans-Jürgen Biersack Hojjat Ahmadzadehfar Jan Bucerius99mTc-sestamibi is a single-photon emission computed tomography (SPECT) radiotracer that is widely used for the imaging of myocardial perfusion, as well as a variety of malignant and benign diseases. 99mTc-Sestamibi - Clinical Applications provides a detailed and informative overview of almost all the oncologic and non-oncologic applications of 99mTc-sestamibi SPECT, including several relatively rare indications. Different disease-related protocols for 99mTc-sestamibi SPECT are presented, and for each disease a comprehensive summary of the relevant pathology and epidemiology is provided. Throughout, there is a strong emphasis on the practical aspects of use of this popular tracer, including instructions for the preparation of several commercially available tracer kits. Clinical practitioners will find this book to be an invaluable guide to the application and benefits of 99mTc-sestamibi SPECT in both the inpatient and the outpatient setting.
Physical Activity and Cancer
by Kerry S. Courneya Christine M. FriedenreichThis book explores in depth the relation between physical activity and cancer control, including primary prevention, coping with treatments, recovery after treatments, long-term survivorship, secondary prevention, and survival. The first part of the book presents the most recent research on the impact of physical activity in preventing a range of cancers. In the second part, the association between physical activity and cancer survivorship is addressed. The effects of physical activity on supportive care endpoints (e.g., quality of life, fatigue, physical functioning) and disease endpoints (e.g., biomarkers, recurrence, survival) are carefully analyzed. In addition, the determinants of physical activity in cancer survivors are discussed, and behavior change strategies for increasing physical activity in cancer survivors are appraised. The final part of the book is devoted to special topics, including the relation of physical activity to pediatric cancer survivorship and to palliative cancer care.
Brainstem Disorders
by Peter P. Urban Louis R CaplanThe topography of the brainstem is complex, and even experienced neurologists find it challenging to localize brainstem lesions and diagnose brainstem disorders. This richly illustrated book provides a comprehensive review of brainstem disorders and presents the clinical knowledge necessary for diagnosis. The opening sections document the brainstem neuroanatomy and discuss current diagnostic methods. The entire spectrum of clinical findings in brainstem disorders is then described, and topodiagnostic aspects of the neurological findings are explained in detail. The descriptions of brain stem disorders are consistently structured and are supported by many MR images and short case reports. In addition to primary brainstem lesions, such as vascular brainstem syndromes, other disorders are considered that do not exclusively show brainstem symptoms or signs, e.g., multiple sclerosis. This book will serve as an invaluable reference work for neurologists in clinical practice or further education.
Integrative Pediatric Oncology
by Patrick J. Mansky Georg Seifert Alfred LänglerThis book covers a broad spectrum of complementary and alternative medicine (CAM) practices employed in pediatric oncology worldwide, with a special focus on the methods widely used in Western countries. It is a scientifically based, practice-oriented handbook that will meet the needs of pediatric oncologists working in medical practices and hospitals. An introductory section includes a comparative overview of current CAM use in pediatric oncology in different countries. Commonly used CAM methods are then discussed in a series of chapters that provide a theoretical description of the method in question, followed by more practically oriented information, including scientific data if applicable. Special attention is paid to the issue of how to integrate each method into conventional pediatric oncology. The closing parts of the book consider aspects of CAM requiring further development, such as institutional research, and provide a road map on establishing integrative pediatric oncology worldwide.
Rare Tumors In Children and Adolescents
by Ines B. Brecht Dominik Schneider Thomas A. Olson Andrea FerrariThis is the first book to be devoted exclusively to rare tumors in children and adolescents, and its aim is to provide up-to-date information on their diagnosis and clinical management. The opening section addresses general issues including epidemiology, risk factors/etiology, biology and genetics, early detection, and screening. It also discusses solutions to assist in the management of rare tumors, such as international networking and internet platforms. In the second section, specific malignancies are described, with practical guidance on diagnostic workup, multimodal therapy, follow-up, and adverse effects. Discussion of differential diagnosis encompasses both frequent and rare tumor types, which should enable the clinician to take rare entities into account during the diagnostic assessment. Each chapter goes on to provide detailed therapeutic guidelines for specific rare tumors. The authors are a multidisciplinary group of specialists who have dedicated themselves to this group of tumors.
Innovations in European Rural Landscapes
by Hubert Wiggering Marina Pintar Hans-Peter Ende Andrea KnierimRural regions in Europe are evolving under powerful boundary conditions such as globalisation, socio-cultural transformations and climate change, which in turn increases natural hazards. The regional land use and the evolvement of landscapes is increasingly shaped trends and drivers like infrastructural, energy or housing needs, globalised agricultural markets, and consumption habits. To face these challenges and to balance competitiveness with social cohesion, the "InnoLand research and development network" induces and accompanies promising land use innovations at the landscape scale in 10 European rural regions. Based on a common conceptual approach among the InnoLand partners, the development and implementation of new competitive strategies is conducted as a science-practice dialogue with strong commitment to the regional policy design for rural development. With this book, the network partners provide an overview and a comparative analysis of selected experimental regional approaches and give examples for the successful tackling of future opportunities and threats.
Decision-Making in Committees
by Nicola Friederike MaaserPolitical and economic institutions are typically governed by committees that face the challenge to reconcile the preferences of their members. How should decision rules be designed to generate fair and sustainable agreements, for example if committee members represent groups of different sizes? This book uses game-theoretic concepts and models to address the issue of political decision-making processes. In addition to providing a survey on basic game-theoretic tools in the analysis of political decisions, the author looks at specific issues such as two-tiered voting systems or the influence of lobbyists on legislative committees, and shows how the models can be applied to real-world contexts such as the EU decision-making institutions.
Wie Mathematiker ticken
by David RuelleDer renommierte mathematische Physiker David Ruelle schildert in dem Buch seine persönlichen Erfahrungen mit berühmten Mathematikern, deren Eigenarten und persönliche Tragödien - aber auch die erhabene Schönheit ihrer Entdeckungen. Jedes Kapitel stellt eine herausragende mathematische Idee und den visionären Verstand dahinter vor. Dabei gibt der Autor Einblick in die einzigartige Denkweise von Mathematikern und zeigt, weshalb er ihre Herangehensweise, um Fragen nach Sinn, Schönheit und Natur der Wirklichkeit zu diskutieren, für die beste hält.
Multiple Criteria Decision Making for Sustainable Energy and Transportation Systems
by Theodor Stewart Jyrki Wallenius Boris Naujoks Matthias EhrgottIn the twenty-first century the sustainability of energy and transportation systems is on the top of the political agenda in many countries around the world. Environmental impacts of human economic activity necessitate the consideration of conflicting goals in decision making processes to develop sustainable systems. Any sustainable development has to reconcile conflicting economic and environmental objectives and criteria. The science of multiple criteria decision making has a lot to offer in addressing this need. Decision making with multiple (conflicting) criteria is the topic of research that is at the heart of the International Society of Multiple Criteria Decision Making. This book is based on selected papers presented at the societies 19th International Conference, held at The University of Auckland, New Zealand, from 7th to 12th January 2008 under the theme "MCDM for Sustainable Energy and Transportation Systems''.
Microbes at Work
by Marta Goberna Heribert Insam Ingrid Franke-WhittleAmong the goals of environmentally sound waste treatment is the recycling of organic wastes. The most practiced options are composting and anaerobic digestion, both processes being carried out by microorganisms. This book provides an overview of the various ways microbes are doing their job and gives the reader an impression of their potential. The sixteen chapters of this book summarize the advantages and disadvantages of treatment processes, whether they are aerobic like composting or work without oxygen like anaerobic digestion for biogas (methane) production. These chapters show the potential of microorganisms to create valuable resources from otherwise wasted materials. These resources include profitable organic, humus-like soil conditioners or fertilizer components which are often suppressive to plant diseases. Composts may thus improve soil carbon sequestration, or support sustainable agriculture by reducing the need for mineral fertilizers or pesticides. If anaerobic digestion is used, the biogas produced may replace fossil fuels. Thus, proper biological waste treatment with the help of microorganisms should contribute to a reduction of anthropogenic greenhouse gas production.