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Organic Bionics
by Michael Higgins Gordon G. Wallace Simon Moulton Robert M.I. KapsaThe first reference on this emerging interdisciplinary research area at the interface between materials science and biomedicine is writtenby pioneers in the field, who address the requirements, current status and future challenges. Focusing on inherently conducting polymers,carbon nanotubes and graphene, they adopt a systematic approach, covering all relevant aspects and concepts: synthesis and fabrication,properties, introduction of biological function, components of bionic devices and materials requirements. Established bionic devices, such asthe bionic ear are examined, as are emerging areas of application, including use of organic bionic materials as conduits for bone re-growth,spinal cord injury repair and muscle regeneration. The whole is rounded off with a look at future prospects in sustainable energy generation and storage.Invaluable reading for materials scientists, polymer chemists, electrotechnicians, chemists, biologists, and bioengineers.
Coronal Seismology: Waves and Oscillations in Stellar Coronae
by Valery M. Nakariakov Valery V. Zaitsev Alexander StepanovThis concise and systematic account of the current state of this new branch of astrophysics presents the theoretical foundations of plasma astrophysics, magneto-hydrodynamics and coronal magnetic structures, taking into account the full range of available observation techniques -- from radio to gamma. The book discusses stellar loops during flare energy releases, MHD waves and oscillations, plasma instabilities and heating and charged particle acceleration. Current trends and developments in MHD seismology of solar and stellar coronal plasma systems are also covered, while recent progress is presented in the observational study of quasi-periodic pulsations in solar and stellar flares with radio, optical, X and gamma rays. In addition, the authors investigate the origin of coherent radio emission from stellar loops, paying special attention to their fine structure. For advanced students and specialists in astronomy, as well as theoretical and plasma physics.
Protein-Ligand Interactions (Methods and Principles in Medicinal Chemistry #53)
by Raimund Mannhold Gerd Folkers Hugo KubinyiInnovative and forward-looking, this volume focuses on recent achievements in this rapidly progressing field and looks at future potential for development. The first part provides a basic understanding of the factors governing protein-ligand interactions, followed by a comparison of key experimental methods (calorimetry, surface plasmon resonance, NMR) used in generating interaction data. The second half of the book is devoted to insilico methods of modeling and predicting molecular recognition and binding, ranging from first principles-based to approximate ones. Here, as elsewhere in the book, emphasis is placed on novel approaches and recent improvements to established methods. The final part looks at unresolved challenges, and the strategies to address them. With the content relevant for all drug classes and therapeutic fields, this is an inspiring and often-consulted guide to the complexity of protein-ligand interaction modeling and analysis for both novices and experts.
Inorganic Nanostructures
by Petra ReinkeThis monograph for young researchers and professionals looking for a comprehensive reference offers an advanced treatment of the topic that extends beyond an introductory work. As such, it systematically covers the inorganic nanostructures in the breadth needed, while presenting them together with the surface science tools used to characterize them, such as electron spectroscopy and scanning probe techniques. The unique challenges in the fabrication of nanostructures are illustrated, and set into context of controlling structure, dimensionality and electronic properties.
Vliesstoffe: Rohstoffe, Herstellung, Anwendung, Eigenschaften, Prüfung
by Hilmar Fuchs Wilhelm AlbrechtSeit der ersten Auflage dieses Referenzwerks gab es sowohl im Bereich der Herstellung als auch Anwendung von Vliesstoffen eine Reihe innovativer Neuerungen, und die weltweite Vliesstoffproduktion hat sich nahezu verdoppelt. Diesen Entwicklungen wird in der zweiten, komplett überarbeiteten Auflage Rechnung getragen und vermittelt allen Vliesstoff-Interessierten - vom Polymerchemiker bis zum Anwender - ein vertieftes Verständnis dieses dynamischen Gebiets. Neben neuen Herstellungsverfahren wie Meltblown, Nanoval, Airlaid, Elektrospinnen sowie Ultraschallverfestigung wurden auch die verschiedenen Verfahren zur Oberflächenmodifizierung, Konfektionierung und zum Recycling von Vliesstoffen mit aufgenommen. Ein besonderer Schwerpunkt liegt bei Vliesstoffen für technische Anwendungen wie Isolation, Schutztextilien und Filtern. Ein separater Abschnitt über Prüfverfahren für Rohstoffe, Zwischen- und Endprodukte erhöht den Wert als unentbehrliches Nachschlagewerk.
New Strategies in Chemical Synthesis and Catalysis
by Bruno PignataroThis volume represents one of the two edited by inviting a selection of young researchers participating to the European Young ChemistAward 2010. The other volume concerns the area of Nanotechnology/Material Science and is titled: Molecules at Work.This book contains the contributions of selected young chemists from the field of synthetic chemistry. The contributions are groupedunder the three following umbrella topics:Synthetic MethodsCatalysisCombinatorial and Chemical BiologyThis volume is an indispensable read for all organic and inorganic chemists, biochemists, chemists working with/on organometallics,and Ph.D. students in chemistry interested in seeing what tomorrow's chemistry will look like.
Molecules at Work
by Bruno PignataroThis book contains the contributions of selected young chemists from the field of nanotechnology and material sciences. The contributionsare grouped under the following umbrella topics:Self assemblyNanomaterialsMolecular MachineryThis volume is an indispensable read for all materials scientists, organic, and inorganic chemists, Ph.D. students in chemistry andmaterial sciences interested in seeing what tomorrow's chemistry will look like.
Process and Plant Safety: Applying Computational Fluid Dynamics
by Jürgen SchmidtThe safe operation of plants is of paramount importance in the chemical, petrochemical and pharmaceutical industries. Best practice in process and plant safety allows both the prevention of hazards and the mitigation of consequences. Safety Technology is continuously advancing to new levels and Computational Fluid Dynamics (CFD) is already successfully established as a tool to ensure the safe operation of industrial plants. With CFD tools, a great amount of knowledge can be gained as both the necessary safety measures and the economic operation of plants can be simultaneously determined. Young academics, safety experts and safety managers in all parts of the industry will henceforth be forced to responsibly judge these new results from a safety perspective. This is the main challenge for the future of safety technology. This book serves as a guide to elaborating and determining the principles, assumptions, strengths, limitations and application areas of utilizing CFD in process and plant safety, and safety management. The book offers recommendations relating to guidelines, procedures, frameworks and technology for creating a higher level of safety for chemical and petrochemical plants. It includes modeling aids and concrete examples of industrial safety measures for hazard prevention.
Ammonium Nitrate Explosives for Civil Applications: Slurries, Emulsions and Ammonium Nitrate Fuel Oils
by Erode G. MahadevanThe book describes the science and technology of formulation and manufacturing of non-nitroglycerine explosives with ammonium nitrate as the main ingredient. Based on the author's industry experience of more than thirty years, it provides an unparalleled treatment of one of the commercially most important classes of explosives and therefore stimulates further research and development efforts in the field of explosives for civil applications.
Lead Optimization for Medicinal Chemists
by Florencio Zaragoza DörwaldSmall structural modifications can significantly affect the pharmacokinetic properties of drug candidates. This book, written by a medicinal chemist for medicinal chemists, is a comprehensive guide to the pharmacokinetic impact of functional groups, the pharmacokinetic optimization of drug leads, and an exhaustive collection of pharmacokinetic data, arranged according to the structure of the drug, not its target or indication. The historical origins of most drug classes and general aspects of modern drug discovery and development are also discussed. The index contains all the drug names and synonyms to facilitate the location of any drug or functional group in the book.This compact working guide provides a wealth of information on the ways small structural modifications affect the pharmacokinetic properties of organic compounds, and offers plentiful, fact-based inspiration for the development of new drugs. This book is mainly aimed at medicinal chemists, but may also be of interest to graduate students in chemical or pharmaceutical sciences, preparing themselves for a job in the pharmaceutical industry, and to healthcare professionals in need of pharmacokinetic data.
Lubricants and Lubrication, 2 Volume Set
by Mang Wilfried DreselPraise for the previous edition: “Contains something for everyone involved in lubricant technology” — Chemistry & Industry This completely revised third edition incorporates the latest data available and reflects the knowledge of one of the largest companies active in the business. The authors take into account the interdisciplinary character of the field, considering aspects of engineering, materials science, chemistry, health and safety. The result is a volume providing chemists and engineers with a clear interdisciplinary introduction and guide to all major lubricant applications, focusing not only on the various products but also on specific application engineering criteria. A classic reference work, completely revised and updated (approximately 35% new material) focusing on sustainability and the latest developments, technologies and processes of this multi billion dollar business Provides chemists and engineers with a clear interdisciplinary introduction and guide to all major lubricant applications, looking not only at the various products but also at specific application engineering criteria All chapters are updated in terms of environmental and operational safety. New guidelines, such as REACH, recycling alternatives and biodegradable base oils are introduced Discusses the integration of micro- and nano-tribology and lubrication systems Reflects the knowledge of Fuchs Petrolub SE, one of the largest companies active in the lubrication business 2 Volumes wileyonlinelibrary.com/ref/lubricants
Cobalt Oxides
by Motin Seikh Bernard RaveauUnparalleled in the breadth and depth of its coverage of all important aspects, this book systematically treats the electronic and magnetic properties of stoichiometric and non-stoichiometric cobaltites in both ordered and disordered phases. Authored by a pioneer and a rising star in the field, the monograph summarizes, organizes and streamlines the otherwise difficult-to-obtain information on this topic. An introductory chapter sets forth the crystal chemistry of cobalt oxides to lay the groundwork for an understanding of the complex phenomena observed in this materials class. Special emphasis is placed on a comprehensive discussion of cobaltite physical properties in different structural families.Providing a thorough introduction to cobalt oxides from a chemical and physical viewpoint as a basis for understanding their intricacies, this is a must-have for both experienced researchers as well as entrants to the field.
Biomolecular Information Processing
by Evgeny KatzEdited by a renowned and much cited chemist, this book covers the whole span of molecular computers that are based on biomolecules. The contributions by all the major scientists in the field provide an excellent overview of the latest developments in this rapidly expanding area. A must-have for all researchers working on this very hot topic. Perfectly complements Molecular and Supramolecular Information Processing, also by Prof. Katz, and available as a two-volume set.
Molecular and Supramolecular Information Processing
by Evgeny KatzEdited by a renowned and much cited chemist, this book covers the whole span of molecular computers that are based on non-biological systems. The contributions by all the major scientists in the field provide an excellent overview of the latest developments in this rapidly expanding area. A must-have for all researchers working on this very hot topic. Perfectly complements Biomolecular Information Processing, also by Prof. Katz, and available as a two-volume set.
Photocatalysis and Water Purification
by Max Lu Pierre PichatWater is one of the essential resources on our planet. Therefore, fresh water and the recycling of waste-water are very important topics in various areas. Energy-saving green technologies are a demand in this area of research.Photocatalysis comprises a class of reactions which use a catalyst activated by light. These reactions include the decomposition of organic compounds into environmental friendly water and carbon dioxide, leading to interesting properties of surfaces covered with a photocatalyst:they protect e.g. against incrustation of fouling matter, they are self-cleaning, antibacterial and viricidal. Therefore, they are attractive candidates for environmental applications such as water purification and waste-water treatment.This book introduces scientists and engineers to the fundamentals of photocatalysis and enlightens the potentials of photocatalysis to increase water quality. Also, strategies to improve the photocatalytic efficacy are pointed out: synthesis of better photocatalysts, combination ofphotocatalysis with other technologies, and the proper design of photocatalytic reactors. Implementation of applications and a chapter on design approaches for photocatalytic reactors round off the book.'Photocatalysis and Water Purification' is part of the series on Materials for Sustainable Energy and Development edited by Prof. G.Q. Max Lu. The series covers advances in materials science and innovation for renewable energy, clean use of fossil energy, and greenhouse gas mitigation and associated environmental technologies.
Characterization of Solid Materials and Heterogeneous Catalysts: From Structure to Surface Reactivity
by Michel Che Jacques C. VédrineThis two-volume book provides an overview of physical techniques used to characterize the structure of solid materials, on the one hand, and to investigate the reactivity of their surface, on the other. Therefore this book is a must-have for anyone working in fields related to surface reactivity. Among the latter, and because of its most important industrial impact, catalysis has been used as the directing thread of the book. After the preface and a general introduction to physical techniques by M. Che and J.C. Vedrine, two overviews on physical techniques are presented by G. Ertl and Sir J.M. Thomas for investigating model catalysts and porous catalysts, respectively. The book is organized into four parts: Molecular/Local Spectroscopies, Macroscopic Techniques, Characterization of the Fluid Phase (Gas and/ or Liquid), and Advanced Characterization. Each chapter focuses upon the following important themes: overview of the technique, most important parameters to interpret the experimental data, practical details, applications of the technique, particularly during chemical processes, with its advantages and disadvantages, conclusions.
Pharmacokinetics and Metabolism in Drug Design (Methods and Principles in Medicinal Chemistry #51)
by Raimund Mannhold Gerd Folkers Hugo KubinyiIn this new edition of a bestseller, all the contents have been brought upto-date by addressing current standards and best practices in the assessment and prediction of ADMET properties. Although the previous chapter layout has been retained, substantial revisions have been made, with new topics such as pro-drugs, active metabolites and transporters covered in detail in a manner useful to the Drug Discovery scientist. The authors discuss the parameters and processes important for the absorption, distribution and retention of drug compounds in the body, plus the potential problems created by their transformation into toxic byproducts. While aimed at all those dealing professionally with the development and application of pharmaceutical substances, the readily comprehensible style makes this book equally suitable for students of pharmacy and related subjects. Uniquely comprehensive, the book relates physicochemistry and chemical structure to pharmacokinetic properties and ultimately drug efficacy and safety.
Management of Chemical and Biological Samples for Screening Applications
by Mark Wigglesworth Terry WoodFilling an obvious gap in the scientific literature, this practice-oriented reference is the first to tie together the working knowledge of largescreening centers in the pharmaceutical and biotechnological field. It spans the entire fi eld of this emerging discipline, from compoundacquisition to collection optimization for specific purposes, to technology and quality control. In so doing, it applies two decades of expertise gathered by several large pharmaceutical companies to current and future challenges in high-throughput screening. With its treatment of libraries of small molecules as well as biobanks containing biomolecules, microorganisms and tissue samples, this reference is universally applicable for any molecular scientist involved in a large screening program.
Polymer Composites, Macro- and Microcomposites: Volume 1: Composites (Green Chemistry Ser. #Volume 16)
by Sabu Thomas Kuruvilla Joseph Koichi Goda Sant Kumar Malhotra Meyyarappallil Sadasivan SreekalaThe first systematic reference on the topic with an emphasis on the characteristics and dimension of the reinforcement. This first of three volumes, authored by leading researchers in the field from academia, government, industry, as well as private research institutions around the globe, focuses on macro and micro composites. Clearly divided into three sections, the first offers an introduction to polymer composites, discussing the state of the art, new challenges, and opportunities of various polymer composite systems, as well as preparation and manufacturing techniques. The second part looks at macro systems, with an emphasis on fiber reinforced polymer composites, textile composites, and polymer hybrid composites. Likewise, the final section deals with micro systems, including micro particle reinforced polymer composites, the synthesis, surface modification and characterization of micro particulate fillers and flakes as well as filled polymer micro composites, plus applications and the recovery, recycling and life cycle analysis of synthetic polymeric composites.
Industrial Crystallization Process Monitoring and Control
by Angelo Chianese Herman J. KramerCrystallization is an important technique for separation and purification of substances as well as for product design in chemical, pharmaceutical and biotechnological process industries. This ready reference and handbook draws on research work and industrial practice of a large group of experts in the various areas of industrial crystallization processes, capturing the essence of current trends, the markets, design tools and technologies in this key field. Along the way, it outlines trouble free production, provides laboratory controls, analyses case studies and discusses new challenges.First the instrumentation and techniques used to measure the crystal size distribution, the nucleation and solubility points, and the chemical composition of the solid and liquid phase are outlined. Then the main techniques adopted to control industrial crystallizers, starting from fundamental approaches to the most advanced ones, including the multivariable predictive control are described. An overview of the main crystallizer types is given with details of the main control schemes adopted in industry as well as the more suitable sensors and actuators.
The Photophysics behind Photovoltaics and Photonics
by Guglielmo LanzaniFrom a leading researcher in optical spectroscopy and electronic properties of novel semiconductors comes this much-needed toolbox title to understand the concepts behind the spectroscopy of advanced organic materials and how they work.The book thus provides basic and practical knowledge on material photophysics for planning, carrying out and understanding experiments in spectroscopy. It contains a collection of simple practical rules for data analysis and interpretation, together with a list of experimental techniques, including the latest methods. Each topic is complemented by examples taken from forefront research on nanomaterials, photovoltaics and photonics, and each chapter includes a discussion, examples, topical boxes, tables and figures. The whole is rounded off by a bibliography for further reading, major references and appendixes containing theoretical derivation and numerical code.The result is a quick guide for the spectroscopist who needs to grasp the concept of the experiments.
BSL3 and BSL4 Agents: Epidemiology, Microbiology and Practical Guidelines
by Baker Ulrich PrahlIn one handy book, this reference gathers all the necessary information on 14 of the most commonly used dangerous groups of pathogens in biosafety level 3 and 4 laboratories. All the chapters are uniformly structured, with a brief overview of the microbiology, pathology, epidemiology and detection methods for each group. In addition, a whole chapter is devoted to the special biosafety requirements, disinfection, decontamination protocols, accident literature and accident procedures, as well as treatment options for all the organisms. This chapter is clearly marked and easy to find when opening the book. Essential literature for the increasing number of BSL3 or BSL4 labs worldwide and for medical facilities intervening in the case of an incident.
Statistical Modelling of Molecular Descriptors in QSAR/QSPR (Quantitative and Network Biology (VCH))
by Frank Emmert-StreibThis handbook and ready reference presents a combination of statistical, information-theoretic, and data analysis methods to meet the challenge of designing empirical models involving molecular descriptors within bioinformatics. The topics range from investigating information processing in chemical and biological networks to studying statistical and information-theoretic techniques for analyzing chemical structures to employing data analysis and machine learning techniques for QSAR/QSPR. The high-profile international author and editor team ensures excellent coverage of the topic, making this a must-have for everyone working in chemoinformatics and structure-oriented drug design.
Systems Biology: A Textbook
by Christoph Wierling Hans Lehrach Axel Kowald Edda Klipp Wolfram Liebermeister Ralf HerwigThis advanced textbook is tailored to the needs of introductory course in Systems Biology. It has a compagnion website (WWW.WILEY-VCH.DE/HOME/SYSTEMSBIOLOGY) with solutions to questions in the book and several additional extensive working models. The book is related to the very successful previous title 'Systems Biology in Practice' and has incorporated the feedback and suggestions from many lecturers worldwide. The book addresses biologists as well as engineers and computer scientists. The interdisciplinary team of acclaimed authors worked closely together to ensure a comprehensive coverage with no overlaps in a homogenous and compelling style.
The Sugar Code: Fundamentals of Glycosciences
by Hans-Joachim GabiusA reader friendly overview of the structure and functional relevance of natural glycosylation and its cognate proteins (lectins), this book is also one of the few books to cover their role in health and disease. Edited by one of the pioneering experts in the field and written by a team of renowned researchers this resource is a perfect introduction for all students in life and medical sciences, biochemistry, chemistry and pharmacy. Website: WWW.WILEY-VCH.DE/HOME/THESUGARCODE