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Trace Metals and Fluoride in Bones and Teeth
by Nicholas D. Priest Frank Van de VyverThis volume is a comprehensive introduction to the analysis, binding, uptake, metabolism, kinetics, modeling, distribution, occurrence, toxicity and chelation of metals and fluoride in the body, with special reference to mineralized tissues. Both toxic and relatively harmless polyvalent cations and anions are considered. Included are some which are stable, and others which are radioactive. While a number are essential trace elements, others have no known metabolic role. Most chapters are concerned with the uptake of bone-seeking ions by the living skeleton, but aspects of the post-mortem uptake of metals and the process of fossilization are also considered. Highlighted are the utility of modern analytical techniques and the more important bone-seeking elements including aluminum, lead, cadmium, fluorine and the radioactive heavy metals including uranium and plutonium. This important publication is of particular value to those in the fields of biochemistry, radioactive waste, geology, physiology, dentistry, orthopedics, radiology and nuclear medicine, urology, industrial hygiene, pharmacology, anthropology, paleontology, and archeology.
Nonsmooth Optimization Methods
by F. GiannessiNonsmooth Optimization Methods and Applications provides an overview of this branch of mathematics, concentrating on the interaction between the theory and its applications.
Cell Surface Carbohydrates and Cell Development
by Minoru FukudaCell Surface Carbohydrates and Cell Development summarizes knowledge on the structure and function of cell surface carbohydrates in development and differentiation. The chapters include reviews on the expression of cell type-specific carbohydrates and their roles in cell-cell interaction. In particular, the role of cell surface carbohydrates in immune cell response, malignant transformation, fertilization, and neural cell development are addressed. This includes the exciting discovery about the role of adhesive molecules in leukocyte-endothellium interaction.Cell Surface Carbohydrates and Cell Development also summarizes the latest knowledge on structure and biosynthesis of carbohydrates, the role of specific carbohydrate modification, and animal lectins. The book will be useful to researchers and students interested in the biology of glycoproteins and biotechnology.
Endocrine Pathology of the Gut and Pancreas
by Yogeshwar DayalThis important new book presents critical information on the clinical and morphological aspects of various endocrinological disorders of the gut and pancreas. Topics include a historical perspective and broad overview of the neuroendocrine component of the gut; hyperplastic proliferations of gastrointestinal endocrine cells; pancreatic endocrine cells and their non-neoplastic proliferations; tumors and lesions; and endocrine differentiation in nonendocrine tumors. The book stresses clinical and pathological aspects of these topics, as well as the pathogenesis, clinicopathological correlations, and diagnostic approaches. Gastroenterologists, pathologists, internists, surgeons, endocrinologists and others interested in endocrinological disorders of the gut and pancreas will discover that this book will be a welcome addition to your reference library.
Group Explicit Methods for the Numerical Solution of Partial Differential Equations (Topics in Computer Mathematics)
by David J. EvansA new class of methods, termed "group explicit methods," is introduced in this text. Their applications to solve parabolic, hyperbolic and elliptic equations are outlined, and the advantages for their implementation on parallel computers clearly portrayed. Also included are the introductory and fundamental concepts from which the new methods are derived, and on which they are dependent. With the increasing advent of parallel computing into all aspects of computational mathematics, there is no doubt that the new methods will be widely used.
Deep Centers in Semiconductors
by Sokrates T. PantelidesExamines several key semiconductor deep centers, all carefully chosen to illustrate a variety of essential concepts. A deep center is a lattice defect or impurity that causes very localized bound states and energies deep in the band gap. For each deep center chosen, a scientist instrumental in its development discusses the theoretical and experimental techniques used to understand that center. The second edition contains four new sections treating recent developments, including a chapter on hydrogen in crystalline semiconductors.
Clean Combustion Technologies: Proceedings of the Second International Conference, Part B
by Woodrow A. Fiveland Christos Papadopoulos Maria da Graca Carvalho F. C LockwoodThe seventy-five referenced papers in this volume represent the second in a series of biannual benchmarks for technologies that maximize energy conversion while minimizing undesirable emissions. Covering the entire range of industrial and transport combustion as well as strategies for energy R&D, these state-of-the-art contributions will be indispensable to mechanical and chemical engineers in academia and industry, and technical personnel in military, energy, and environmental agencies of government.
Ulcer Disease: New Aspects of Pathogenesis and Pharmacology
by Sandor Szabo Carl J. PfeifferThe latest data on the pathogenesis of ulcer disease is presented in this text, with the emphasis that an understanding of the pathogenesis and etiology of ulcer diseases represents the most rational approach to pharmacology - the prevention and treatment of ulcer disease. Early and late biochemical and functional changes, morphologic stages of the injury and healing phases, as well as vascular factors in ulceration are highlighted. In addition, new pathogenetic elements on neuroendocrine and other endogenous modulators and circadian rhythms in ulcerogenesis are covered. The section on new pharmacology consists of several chapters presenting new animal models of gastric, small intestinal and colonic ulcers because in vivo models represent the basis to test and accurately detect new antiulcer drugs. A large series of chapters cover new drugs for ulcer prevention and treatment. This book is indispensible to investigators in basic and applied research, academic and industrial pharmacologists and clinicians in gastroenterology.
Brand Activism: Advertising and the Ethics of Visibility (Routledge Critical Advertising Studies)
by Marco ScalviniThis book critically examines how brands determine the visibility of social issues through their advertising practices, informing the ways we are persuaded to feel, think, and act as consumers and citizens.Through a critical analysis of brand responses to ongoing geopolitical events, such as the Ukrainian conflict and the war in Gaza, Scalvini demonstrates how commercial objectives drive ethical stances, leading to the prioritization of certain profit-driven narratives and the exclusion of more politicized ones. Drawing on in-depth interviews with post-Millennial consumers across North America, Europe, and Asia, Brand Activism critiques brands’ reluctance to engage with politically sensitive topics, particularly those affecting the Global South, arguing that this avoidance distorts the representation of moral responsibility in advertising. This book examines how ‘ordinary’ consumers—those not strongly aligned with activist consumption—negotiate the idea that they should take moral responsibility for their spending choices. However, it also discusses the rise of a new generation of consumer activists who reject superficial brand gestures and demand accountability for global justice. Case studies from brands such as Nike, Patagonia, Gillette, Dove, and Ben & Jerry’s are explored in detail to unpack the symbolic, rhetorical, and discursive strategies by which present brand activist campaigns are being hollowed out and re-articulated into a moral discourse.This is valuable and insightful reading for advanced students and researchers in Media and Communication, Sociology, Marketing, and Business disciplines.
The Collected Papers of Bertrand Russell, Volume 3: Toward the 'Principles of Mathematics' 1900-02 (The Collected Papers of Bertrand Russell)
by Gregory H. MooreThis volume shows Russell in transition from a neo-Kantian and neo-Hegelian philosopher to an analytic philosopher of the first rank. During this period his research centred on writing The Principles of Mathematics where he drew together previously unpublished drafts. These shed light on Russell's paradox. This material will alter previous accounts of how he discovered his paradox and the related paradox of the largest cardinal. The volume also includes a previously unpublished draft of an early attempt to solve his paradox, as well as the earliest known version of his generalised relation arithmetic. It contains three articles which have never previously been published in English.
Encoded Archival Description on the Internet
by Wendy Duff Daniel V PittiArchivists and librarians: here is the perfect introduction to archival description and its latest technological applications! Encoded Archival Description on the Internet introduces a variety of perspectives that will assist you in deciding whether EAD is an appropriate tool in a given context and, if it is, provides the knowledge you need to begin planning, organizing, and implementing projects and programs in your library. This informative book: shows how archival description differs from bibliographic description presents EAD as a standard and shows its relation to the MARC format and other standards discusses implementation issues examines museum use of EAD gives you an overview of the history of the development of EAD explores the reference implications of EAD discusses implications for nontraditional users examines the concept of union-universal access to archivesEAD version 1.0 was formally released by the Society of American Archivists and the Library of Congress Network Development and MARC Standards Office in autumn 1998. Since then, a great number of institutions have invested significant time and money to prepare for implementation of EAD programs. The most compelling reason for EAD’s success is that, in the words of Editors Pitti and Duff, “Archivists recognize in EAD their shared principles and practice, and have embraced EAD not as a full realization of all of their expectations, but as common ground upon which they can negotiate and realize the future of one of the profession’s central responsibilities.”Encoded Archival Description on the Internet shows how EAD will not only benefit the public, but also librarians and archivists. It describes how information professionals will now be able to easily share information about complementary records and collections and to “virtually” integrate collections related by provenance but dispersed administratively or by geographic distance.
Immune System Accessory Cells
by Vaclav Vetvicka Lubor FornusekImmune System Accessory Cells provides a comprehensive survey of all types of antigen-presenting and accessory cells. Macrophages are emphasized through descriptions of different types of endocytosis, other major properties, and all basic and new information concerning macrophages as antigen-presenting cells. Other topics covered include the impact of the immunodeficient state on accessory functions, the evolutionary emergence of accessory functions, and the role of various cell types in defense reactions in major assemblages of Metazoa. The book also presents a chapter describing the phylogenetic aspects of accessory functions, which traces the first accessory cells during the evolution of living matter.Immune System Accessory Cells is an excellent reference for immunologists, cell biologists, and others interested in developing an understanding of the roles of accessory cells in all facets of immune reactions.
A Study of Enzymes, Volume II
by Stephen A. KubyThis comprehensive monograph consists of two parts: Volume I, entitled Enzyme Catalysis, Kinetics, and Substrate Binding; and Volume II, entitled Mechanism of Enzyme Action. Volume I focuses on several aspects of enzyme catalytic behavior, their steady-state and transient-state kinetics, and the thermodynamic properties of substrate binding. Packed with figures, tables, schemes, and photographs, this volume contains over 1,000 references, including references regarding enzymology's fascinating history. This comprehensive book is of particular interest to enzymology students, teachers, and researchers. Volume II presents selected "cutting edge" examples of techniques and approaches being pursued in biochemistry. This up-to-date resource includes 11 chapters, which illustrate important theoretical and practical aspects of enzyme mechanisms. It also features selected examples in which today's most important techniques, ideas, and theories are used to elaborate on the intricate nature of enzyme action mechanisms. This particular volume provides important information for both the novice and the seasoned investigator.
Critical Care Manual of Clinical Nursing Procedures
by Chris Hill Suzanne Bench Nicki CredlandCritical Care Manual of Clinical Nursing Procedures The second edition of Critical Care Manual of Clinical Nursing Procedures is a practical overview of essential procedures for the care of critically ill patients. Beginning with chapters outlining the current scope of critical care, the book adopts a systematic stage-by-stage approach from admission to discharge. At each stage, it provides insights into physiology, key procedures, and the relevant evidence base. Now fully updated to incorporate the latest research and best practices, this volume is poised to remain an indispensable resource for the next generation of critical care providers. Readers of the second edition will find: In-depth, beat-by-beat analysis of key procedures in critical careInterventions underpinned by the latest evidenceContent aligned with the National Critical Care Competency Framework and endorsed by the British Association of Critical Care Nurses Critical Care Manual of Clinical Nursing Procedures is ideal for nurses working in a critical care unit, nurses undertaking post-qualification specialist courses in critical care, or other healthcare professionals working as part of a critical care team.
Histones and Other Basic Nuclear Proteins
by Gary S. Stein Janet L. SteinThis comprehensive book is a compilation of Professor Lubomir S. Hnilica's twenty years of research experimentally addressing the chemistry and the biological functions of chromosomal proteins. The histones and other nuclear proteins found associated with DNA in a number of tissues and cell types are featured. Lubomir Hnilica played a major role in establishing the extent to which these basic chromosomal polypeptides are conserved and the manner in which they interact with DNA to modify chromatin structure. In addition, non-histone chromosomal protein research is explained, and his technique of applying several biochemical and immunological approaches to the characterization of this complex and heterogeneous class of chromosomal polypeptides is discussed. Highlighted is the use of chemical crosslinking for studying protein/DNA interactions in intact cells. The proteins as well as the structure, organization, and regulation of the genes are also presented.
Endothelin Receptors: From the Gene to the Human (Handbooks in Pharmacology and Toxicology)
by Jr. RuffoloSince the discovery of endothelin, major advances have been made in understanding the molecular structure and function of the endothelin receptors. At least two subtypes of receptors, designated ETA and ETB, have been identified through biochemical and pharmacological techniques. These subtypes are cloned and expressed and additional subtypes appear to exist. The biochemical events involved in the signal transduction processes that ultimately activate the cellular machinery involved in the end-organ responses are presented, as are the mechanisms by which the receptors recognize specific and different G-proteins. Functions mediated by the receptors at the cellular, tissue and, organ level are reviewed in detail, as well as the roles that they may play a part in the physiologic and pathophysiologic processes in animals and in humans.This book is unique in its breadth of scope. The most recent and important advances, from the intracellular level of the nucleus to the functional effect that endothelin receptors mediate in intact organs, are compiled and reviewed.
Molecular & Cell Biology of the Liver
by Albert V. LeBoutonMolecular and Cell Biology of the Liver features the latest research findings regarding liver structure and function. A unique feature of the book is the brief science reviews that are included in each chapter which provide essential background information to allow readers to better grasp the subject matter within a chapter. The book covers liver biology from the molecular level to groups of liver cells and explains how groups of hepatocytes interact in similar microenvironments. Other important cell types found in the liver are also examined. Illustrations ranging from electron micrographs to fully rendered drawings act as visual aids to help readers understand complex structural-functional interactions. Molecular and Cell Biology of the Liver will benefit hepatologists, gastroenterologists, cell biologists, anatomists, toxicologists, and other researchers interested in liver structure and function.
Material Recovery Facility Design Manual
by 0 Peer Consultants CallRecoveryEconomic factors discussed include purchase price, utility requirements, maintenance costs, labor costs, auxiliary equipment purchase needs, sizing, space requirements, redundancy requirements, and all aspects necessary for the development of performance and equipment specifications. Material Recovery Facility Design Manual is essential for solid waste planners, engineers, and anyone else involved with startup, implementation, and acceptance testing of MRF equipment and systems.
Cryopreservation of Plant Cells and Organs
by K.K. KarthaThis monograph will put the topic of Cryopreservation of Plant Cells and Organs in perspective. Originally published in 1985.
Roles of Copper in Lipid Metabolism
by Kai Y. LeiThe aim of this book is to provide a reference for researchers in the field of trace mineral and lipid metabolism. It addresses the influence of dietary copper status on cholesterol, lipoprotein and apolipoprotein metabolism as well as lipoprotein receptor characteristics. This fascinating volume critically reviews alterations in long chain fatty acid, prostaglandin and cardiac lipid metabolism, as well as arterial morphology induced by copper deficiency. Furthermore, it presents the theoretical relationship plus the anatomical, chemical and physiological similarities between copper deficiency and ischemic heart disease. This reading is indispensable for investigators interested in the role of copper in lipid metabolism.
Elemental Analysis of Biological Systems: Biological, Medical, Environmental, Compositional, and Methodological Aspects, Volume I
by G. Venkatesh IyengarThe purpose of this volume is to emphasize the fact that biological trace element research is a multidisciplinary science which requires a prudent combination of biological insight and analytical awareness. The text frequently stresses that accurate measurements on biologically and analytically "valid" samples hold the key for success in future investigations. It reminds the analytical scientists and the life sciences researchers that their perceptions should extend beyond conventional limits - namely, the former as generators of data and the latter as interpreters of those findings. This book enables the reader to understand the intricacies of elemental composition studies in biological systems, and also provides a valuable source of information to biologists, biochemists, physicians, nutritionists and related scientific workers who intend to draw meaningful conclusions from the analytical findings.
Airway Smooth Muscle: Modulation of Receptors and Response
by Devendra K. Agrawal Robert G. TownleyAirway smooth muscle plays a dominant role in bronchial asthma, as well as a significant role in various pulmonary diseases, such as chronic bronchitis, cystic fibrosis and emphysema. Myogenic, neurogenic, and humoral factors control airway smooth-muscle tone. This text provides a state-of-the-art summary and critical discussion of airway smooth muscle from a multidisciplinary point of view. Topics discussed include morphology, biochemical regulation, mechanical and electrophysiological behavior and reflex control of smooth muscle; the epithelium-derived relaxing factor; and methods to measure smooth muscle function in vivo in humans and experimental animals, as well as in vitro in isolated airway tissues. Also discussed are calcium and potassium channels and receptors for adrenergic, cholinergic and histaminergic systems in modulating receptor-response coupling in airway smooth muscle. Airway Smooth Muscle: Modulation of Receptors and Response provides essential information for researchers, teachers, pulmonary specialists and allergists, and students interested in learning about airway smooth muscle.
Papillomaviruses and Human Cancer
by Herbert PfisterThis volume gives special reference to papillomaviruses in benign precursor lesions related to genital tumors, plus it provides a basis for a more reproducible evaluation of the pathology of papillomavirus-induced lesions. It deals with the molecular biology of papillomaviruses as it relates to our understanding of viral cell transformation and malignant conversion. Written in a comprehensive, easy-to-read format, this book covers points of medical interest such as diagnosis, therapy, and prospects for vaccination. This fascinating text provides current, state-of-the-art practices for immediate and future medical research. Virologists, microbiologists, and cancer researchers will find this work interesting and resourceful.
Heme Oxygenase: Clinical Applications and Functions
by Mahin D. Maineshis book provides a comprehensive summary of data from basic research on characterization, regulation, and function of heme oxygenase in mammalian systems. The book also includes a major section that covers the currently used clinical methods to suppress neonatal jaundice with emphasis on the newly developed use of synthetic metalloporophyrins. This book will be welcomed by researchers and students in pharmacology, biochemistry, pharmacy, neonatology, hematology, internal medicine, and endocrinology.
Found in a Bookshop: The perfect read for autumn - heart-warming and unforgettable
by Stephanie ButlandThe life-affirming and unforgettable novel from the author of Lost for Words'I read this book in one sitting, it made me smile and made me wipe a tear from my eye too' ⭐ ⭐ ⭐ ⭐ ⭐'This book had me sitting up into the small hours. Such a lovely read, very relatable and touching' ⭐ ⭐ ⭐ ⭐ ⭐'I LOVED this book . . . A joy to read' ⭐ ⭐ ⭐ ⭐ ⭐'One of the best books I've read in quite some time' ⭐ ⭐ ⭐ ⭐ ⭐Loveday Cardew's beloved Lost for Words bookshop, along with the rest of York, has fallen quiet. At the very time when people most need books to widen their horizons, or escape from their fears, or enhance their lives, the doors are closed. Then the first letter comes.Rosemary and George have been married for fifty years. Now their time is running out. They have decided to set out on their last journey together, without ever leaving the bench at the bottom of their garden in Whitby. All they need is someone who shares their love of books.Suddenly it's clear to Loveday that she and her team can do something useful in a crisis. They can recommend books to help with the situations their customers find themselves in: fear, boredom, loneliness, the desire for laughter and escape.And so it begins.'A delightful and original concept about how a second hand bookshop can heal a community' Katie Fforde'The perfect book to curl up with . . . It's heartwarming, emotional and full of kindness. A lovely and life-affirming novel' Sara Nisha Adams'What a lovely book - so assured and gentle, full of compassion and replete with astute observations of human nature and behaviour' Carys Bray'A really moving read - with great book recommendations included, too!' My Weekly'I truly loved this book; it made me laugh out loud and also had me choked up a few times too' ⭐ ⭐ ⭐ ⭐ ⭐'Stephanie's stories are thoughtful and warm, written with much humour, and most importantly care. I'd recommend them to anyone, and especially those recovering from a broken heart' ⭐ ⭐ ⭐ ⭐ ⭐'It made me laugh, it made me cry and left me with a feeling of community spirit - I will definitely be recommending this to others, it is a fantastic read' ⭐ ⭐ ⭐ ⭐ ⭐'This book is going straight on my list of top ten books' ⭐ ⭐ ⭐ ⭐ ⭐'Her writing is utterly engaging and this book truly moved me. Compassionate, unusual, original and full of wonderful characters' ⭐ ⭐ ⭐ ⭐ ⭐'Beautiful, heartwarming, a true gift of a book' ⭐ ⭐ ⭐ ⭐ ⭐