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Anamnese en gespreksvoering
by A. J. Kooter T.O.H. de Jongh R. Franssen N. Th. van den Broek J.A. de Wilde J. Damen† A. Kaemingk G.J.M. RoodbolEen zorgvuldige anamnese blijft de grondslag van de medische diagnostiek. Tijdens het afnemen van een anamnese moet je je bewust zijn van de aard en het doel van het vraagproces. Met Anamnese en gespreksvoering leer je hoe je een gestructureerde anamnese afneemt op basis van het Calgary-Cambridge model, en hoe je effectieve gesprekken voert met patiënten. Naast het medisch diagnostisch spoor speelt ook het patiëntenperspectief een belangrijke rol. Wat wil jouw patiënt met het gesprek bereiken, hoe ervaart hij zijn klachten? Anamnese en gespreksvoering komt voort uit het Leerboek anamnese en is volledig herzien en uitgebreid.Ook verschillende anamnesevormen zoals klachtgerichte anamnese, hypothesegestuurde anamnese en tractusanamnese worden besproken.Voor de bruikbaarheid in de praktijk worden hierbij veel voorbeelden van anamnesevragen gegeven met de betekenis van de mogelijke antwoorden. Ook lees je achtergrondinformatieover de patiënt, dearts en hun behandelrelatie, gespreksvaardigheden en verschillende consultmodellen. Tot slot is in deze herziening veel aandacht voor andere vormen van gespreksvoering zoals gezondheidsgerichte gesprekken, motiverende gespreksvoering en informerende gesprekken.Bij dit boek hoort een website. Hierop staan behalve de inhoud van dit boek ook een aantal videoconsulten, met voorbeelden van anamnese afnemen en enkele gespreksfragmenten in de praktijk. Anamnese en gespreksvoering is een praktische en onmisbare gids voor medische studenten, verpleegkundig specialisten en physician assistants in opleiding die een goede, patiëntgerichte, diagnostische anamnese willen afnemen en hun gespreksvoering willen verbeteren. Ook artsen en andere medische hulpverleners kunnen met dit boek hun anamnesevaardigheid en gespreksvoering verbeteren.
Cold Burn: A National Parks Thriller (A National Parks Thriller)
by Jon Land Jeff Ayers A. J. LandauAgent Michael Walker returns when multiple deaths at Glacier Bay National Park are just the first steps in a potential global disaster.National Park Service investigator Michael Walker is battling smugglers stealing priceless artifacts when he’s dispatched to Glacier Bay National Park in Alaska, where, in the first stage of a potential global disaster, a team of scientists has gone missing.Meanwhile, in Florida’s Everglades National Park, FBI special investigator Gina Delgado traces the murder of an environmental science intern back to another U.S. Geological Survey team’s ongoing experiments that are decimating the fragile ecosystem. That is before she’s dispatched to the scene of a sunken U.S. nuclear submarine, the entire crew of which has inexplicably been killed.The connection between these disparate investigations lies in a deadly prehistoric organism, frozen for thousands of years in the ice until global warming brings it back to life in what could mean the death of all life on Earth. An organism that a rogue billionaire sees as the ultimate fuel source and a Russian strongman views as the ultimate weapon that can shift the global balance of power forever. Against that backdrop, Walker and Delgado find themselves desperately doing battle across multiple fronts against an ancient, unstoppable enemy.
Leave No Trace: A National Parks Thriller (A National Parks Thriller)
by Jon Land Jeff Ayers A. J. LandauThe Statue of Liberty is the target of a terrorist attack, the first in a possible series of attacks, in this thrilling series from A. J. Landau, featuring Special Agent Michael Walker of the National Park Service.In a daring, brutal act of terrorism, an explosion rocks and topples the Statue of Liberty. Special Agent Michael Walker of the National Park Service is awakened by his boss with that news and sent to New York as the agent-in-charge. Not long after he lands, he learns two things - one that Gina Delgado of the FBI has been placed in charge of the investigation as the lead of the Joint Terrorism Task Force and two, that threats of a second terrorism attack are already being called into the media. While barred from the meetings of the Joint Task Force for his lack of security clearance, Walker finds a young boy among the survivors with a critical piece of information - a video linking the attackers to the assault.As a radical domestic terrorist group, led by a shadowy figure known only as Jeremiah, threatens further attacks against America's cultural symbols, powerful forces within the government are misleading the investigation to further their own radical agenda.
The Minotaur Sampler, Volume 10: New Books to Make Your Heart Race (The Minotaur Sampler #10)
by Lindy Ryan Kat Ailes Christina Estes Jenny Hollander A. J. LandauLooking for a new book that will make your heart race? The tenth edition of The Minotaur Sampler compiles the beginnings of five can't-miss novels—either standalone or first in series—publishing Winter 2024 for free for easy sampling.First in Series: In Leave No Trace, the Statue of Liberty is the target of a terrorist attack, the first in a possible series of attacks, in this new series featuring Special Agent Michael Walker of the National Park Service.First in Series: Fresh, funny and heartfelt, The Expectant Detectives is a charming debut mystery about a group of soon-to-be moms-turned-detectives.Standalone: Everyone Who Can Forgive Me is Dead is a debut thriller about a woman who is trying to escape the past and the horrific event she witnessed at the prestigious journalism school she attended.First in Series: Equal parts thought-provoking and entertaining, Emmy Award winning reporter Christina Estes introduces Jolene Garcia in her Tony Hillerman Prize winning debut, Off the Air.First in Series: A crackling mystery-horror novel with big-hearted characters and blood-soaked Southern charm, Bless Your Heart is a gasp-worthy delight from start to finish.
After Lincoln: How the North Won the Civil War and Lost the Peace
by A. J. LangguthA brilliant evocation of the post-Civil War era by the acclaimed author of Patriots and Union 1812. After Lincoln tells the story of the Reconstruction, which set back black Americans and isolated the South for a century.With Lincoln’s assassination, his “team of rivals,” in Doris Kearns Goodwin’s phrase, was left adrift. President Andrew Johnson, a former slave owner from Tennessee, was challenged by Northern Congressmen, Radical Republicans led by Thaddeus Stephens and Charles Sumner, who wanted to punish the defeated South. When Johnson’s policies placated the rebels at the expense of the black freed men, radicals in the House impeached him for trying to fire Secretary of War Edwin Stanton. Johnson was saved from removal by one vote in the Senate trial, presided over by Salmon Chase. Even William Seward, Lincoln’s closest ally, seemed to waver. By the 1868 election, united Republicans nominated Ulysses Grant, Lincoln's winning Union general. The night of his victory, Grant lamented to his wife, “I’m afraid I’m elected.” His attempts to reconcile Southerners with the Union and to quash the rising Ku Klux Klan were undercut by post-war greed and corruption. Reconstruction died unofficially in 1887 when Republican Rutherford Hayes joined with the Democrats in a deal that removed the last federal troops from South Carolina and Louisiana. In 1964, President Lyndon Johnson signed a bill with protections first proposed in 1872 by the Radical Senator from Massachusetts, Charles Sumner.
Driven West
by A. J. LangguthBy the acclaimed author of the classic Patriots and Union 1812, this major work of narrative history portrays four of the most turbulent decades in the growth of the American nation. After the War of 1812, President Andrew Jackson and his successors led the country to its manifest destiny across the continent. But that expansion unleashed new regional hostilities that led inexorably to Civil War. The earliest victims were the Cherokees and other tribes of the southeast who had lived and prospered for centuries on land that became Alabama, Mississippi, and Georgia. Jackson, who had first gained fame as an Indian fighter, decreed that the Cherokees be forcibly removed from their rich cotton fields to make way for an exploding white population. His policy set off angry debates in Congress and protests from such celebrated Northern writers as Ralph Waldo Emerson. Southern slave owners saw that defense of the Cherokees as linked to a growing abolitionist movement. They understood that the protests would not end with protecting a few Indian tribes. Langguth tells the dramatic story of the desperate fate of the Cherokees as they were driven out of Georgia at bayonet point by U.S. Army forces led by General Winfield Scott. At the center of the story are the American statesmen of the day--Henry Clay, John Quincy Adams, John C. Calhoun--and those Cherokee leaders who tried to save their people--Major Ridge, John Ridge, Elias Boudinot, and John Ross. Driven West presents wrenching firsthand accounts of the forced march across the Mississippi along a path of misery and death that the Cherokees called the Trail of Tears. Survivors reached the distant Oklahoma territory that Jackson had marked out for them, only to find that the bloodiest days of their ordeal still awaited them. In time, the fierce national collision set off by Jackson's Indian policy would encompass the Mexican War, the bloody frontier wars over the expansion of slavery, the doctrines of nullification and secession, and, finally, the Civil War itself. In his masterly narrative of this saga, Langguth captures the idealism and betrayals of headstrong leaders as they steered a raw and vibrant nation in the rush to its destiny.
Hidden Terrors: The Truth About U.S. Police Operations in Latin America (Forbidden Bookshelf #27)
by A. J. LangguthA &“devastating&” exposé of the United States&’ Latin American policy and the infamous career and assassination of agent Dan Mitrione (Kirkus Reviews). In 1960, former Richmond, Indiana, police chief Dan Mitrione moved to Brazil to begin a new career with the United States Agency for International Development. During his ten years with the USAID, Mitrione trained and oversaw foreign police forces in extreme counterinsurgency tactics—including torture—aimed at stomping out communism across South America. Though he was only a foot soldier in a larger secret campaign, he became a symbol of America&’s brutal interventionism when he was kidnapped and executed by Tupamaro rebels in Montevideo, Uruguay. In Hidden Terrors, former New York Times Saigon bureau chief A. J. Langguth chronicles with chilling detail Mitrione&’s work for the USAID on the ground in South America and Washington, DC, where he shared his expertise. Along the way, Langguth provides an authoritative overview of America&’s efforts to destabilize communist movements and prop up military dictators in South America, presenting a &“powerful indictment of what the United States helped to bring about in this hemisphere&” (The New York Times). Even today, the tactics Mitrione helped develop continue to influence operations in Guantanamo Bay, Cuba, and black sites around the globe.
Our Vietnam: The War 1954-1975
by A. J. LangguthWinner of the Overseas Press Club's Cornelius J. Ryan Award for Best Nonfiction Book, the Commonwealth Club of California's Gold Medal for Nonfiction, and the PEN Center West Award for Best Research NonfictionTwenty-five years after the end of the Vietnam War, historian and journalist A. J. Langguth delivers an authoritative account of the war based on official documents not available earlier and on new reporting from both the American and Vietnamese perspectives. In Our Vietnam, Langguth takes us inside the waffling and deceitful White Houses of Kennedy, Johnson, and Nixon; documents the ineptness and corruption of our South Vietnamese allies; and recounts the bravery of soldiers on both sides of the war. With its broad sweep and keen insights, Our Vietnam brings together the kaleidoscopic events and personalities of the war into one engrossing and unforgettable narrative.
Patriots: The Men Who Started the American Revolution
by A. J. LangguthWith meticulous research and page-turning suspense, Patriots brings to life the American Revolution—the battles, the treacheries, and the dynamic personalities of the men who forged our freedom.George Washington, John Adams, Samuel Adams, Ben Franklin, Thomas Jefferson, Patrick Henry—these heroes were men of intellect, passion, and ambition. From the secret meetings of the Sons of Liberty to the final victory at Yorktown and the new Congress, Patriots vividly re-creates one of history's great eras.
Union 1812
by A. J. LangguthBy the author of the acclaimed Patriots: The Men Who Started the American Revolution, a gripping narrative that tells the story of the second and final war of independence that secured the nation's independence from Europe and established its claim to the entire continent. The War of 1812 has been ignored or misunderstood. Union 1812 thrillingly illustrates why it must take its place as one of the defining moments in American history.
A Dictionary of Neurological Signs, 4th Edition: Clinical Neurosemiology
by A. J. LarnerThis updated and expanded Fourth Edition is an alphabetical listing of commonly presenting neurological signs designed to guide the physician toward the correct clinical diagnosis. The dictionary is focused, problem-based and concise. <P><P> The structured entries in this practical, clinical resource provide summaries of a wide range of neurological signs. Each entry includes: a definition of the sign; a brief account of the clinical technique required to elicit the sign; a description of the other signs which may accompany the index sign; an explanation of pathophysiological and/or pharmacological background; differential diagnosis; brief treatment details; and where known, the neuroanatomical basis of the sign. <P><P> A Dictionary of Neurological Signs, Fourth Edition, is an indispensable reference for all students, trainees, and clinicians who care for patients with neurological disorders, and could also be used in preparation for exams, since each entry is a snapshot of a specific disorder or disease.
A Dictionary of Neurological Signs, Third Edition
by A. J. LarnerThe first two editions of the Dictionary of Neurological Signs were very well-received by readers and reviewers alike. Like those editions, this Third Edition, updated and expanded, can be almost as well described in terms of what the book is not, along with details about what it is. The Dictionary is not a handbook for treatment of neurological disorders. While many entries provide the latest treatment options, up-to-the-minute therapies are not discussed in bedside level detail. The Dictionary is not a board review book because it is not in Q&A format but could easily serve in that capacity since each entry is a fairly complete snapshot of a specific disorder or disease. The Dictionary is an alphabetical listing of commonly presenting neurological signs designed to guide the physician toward the correct clinical diagnosis. The Dictionary is focused, problem-based, concise and practical. The structured entries in this practical, clinical resource provide a thumbnail of a wide range of neurological signs. Each entry includes: * A definition of the sign * A brief account of the clinical technique required to elicit the sign * A description of the other signs which may accompany the index sign * An explanation of pathyophysiological and/or pharmacological background * Differential diagnosis * Brief treatment details Where known, these entries also include the neuroanatomical basis of the sign. The Dictionary of Neurological Signs, Third Edition, is an indispensable reference for all students, trainees, and clinicians who care for patients with neurological disorders.
Cognitive Screening Instruments: A Practical Approach
by A. J. LarnerCognitive Screening Instruments: A Practical Approach provides a practical and structured overview of some of the most commonly used and easily available cognitive screening instruments applicable in the outpatient clinic and bedside setting. Dementia and cognitive disorders are now recognised as an increasing public health problem, both in terms of patient numbers and cost, as populations age throughout the world. Despite this, many patients with dementia never receive a formal diagnosis, with implications for their appropriate care and management. Diagnostic tests which identify cases of dementia therefore have an important role. Expert authors from around the world equip the reader of Cognitive Screening Instruments: A Practical Approach with clear instructions on the usage of each screening instrument, its strengths and weaknesses, the time required for administration, and rules on scoring, such as how to correct for variations in the patient's age or education, and suggested cut-off scores. Cognitive Screening Instruments: A Practical Approach is a handy, illustrated guide and a valuable diagnostic aid for practitioners working closely with patients with dementia and mild cognitive impairment. This volume will be of use both to clinicians and to professionals in disciplines allied to medicine who are called upon to assess patients with possible cognitive disorders, including neurologists, old age psychiatrists, neuropsychologists, primary care physicians, dementia support workers, and members of memory assessment teams.
Cognitive Screening Instruments: A Practical Approach
by A. J. LarnerCognitive Screening Instruments: A Practical Approach provides a practical and structured overview of some of the most commonly used and easily available cognitive screening instruments applicable in the outpatient clinic and bedside setting. Dementia and cognitive disorders are now recognised as an increasing public health problem, both in terms of patient numbers and cost, as populations age throughout the world. Despite this, many patients with dementia never receive a formal diagnosis, with implications for their appropriate care and management. Diagnostic tests which identify cases of dementia therefore have an important role. Expert authors from around the world equip the reader of Cognitive Screening Instruments: A Practical Approach with clear instructions on the usage of each screening instrument, its strengths and weaknesses, the time required for administration, and rules on scoring, such as how to correct for variations in the patient's age or education, and suggested cut-off scores. Cognitive Screening Instruments: A Practical Approach is a handy, illustrated guide and a valuable diagnostic aid for practitioners working closely with patients with dementia and mild cognitive impairment. This volume will be of use both to clinicians and to professionals in disciplines allied to medicine who are called upon to assess patients with possible cognitive disorders, including neurologists, old age psychiatrists, neuropsychologists, primary care physicians, dementia support workers, and members of memory assessment teams.
Dementia in Clinical Practice: Pragmatic Studies in the Cognitive Function Clinic
by A. J. LarnerThis concise, pragmatic, pocket-sized book addresses neurological contributions to the diagnosis and management of dementia through a longitudinal examination of the work undertaken in a dedicated neurological dementia clinic. <P><P> It covers the use of cognitive and non-cognitive screening instruments and their diagnostic utility and the use of other diagnostic investigations: neuroimaging, neurophysiology and neuropathology. The diagnostic mix is discussed in terms of both neuropsychological syndromes and neurological diagnoses, as is the use of conventional treatments for dementia and the impact of national directives (e.g. NICE, National Dementia Strategy) on day-to-day clinical practice. <P> Dementia in Clinical Practice: A Neurological Perspective, Second Edition is an illustrated, practical resource for medical professionals involved in the assessment and management of dementia patients. It is of particular benefit to neurologists, psychiatrists, geriatricians, primary care practitioners and those working in the fields of neuropsychology, psychology, occupational therapy, speech and language therapy and nursing.
Dementia in Clinical Practice: Pragmatic Studies in the Cognitive Function Clinic
by A. J. LarnerThis expanded, updated third edition summarizes the pragmatic diagnostic accuracy studies of neurological signs and cognitive and non-cognitive screening instruments undertaken in the author’s clinic in the context of day-to-day practice involving patients with cognitive disorders including dementia. A new chapter devoted to comparing and combining instruments is included, and illustrative case studies have been included where relevant. Dementia in Clinical Practice: A Neurological Perspective, Third Edition is a practical resource for medical professionals involved in the assessment and management of patients with dementia and cognitive disorders. It may be of particular interest to neurologists, psychiatrists, geriatricians, primary care practitioners and those working with patients with cognitive impairment in the fields of neuropsychology, psychology, occupational therapy, speech and language therapy and nursing.
Dementia in Clinical Practice: Studies in the Dementia Clinic
by A. J. LarnerDementia in Clinical Practice: A Neurological Perspective addresses neurological contributions to the diagnosis and management of dementia through a longitudinal examination of the work undertaken in dedicated neurological dementia clinics. This concise, pragmatic handbook covers: The use of cognitive screening instruments and their diagnostic utility. The use of non-cognitive (functional, behavioural, neurovegetative) screening instruments and their diagnostic utility. The use of other diagnostic investigations: neuroimaging, neurophysiology, neuropathology. The diagnostic mix in terms of both neuropsychological syndromes and neurological diagnoses. The use of conventional treatments for dementia. The impact of national directives (e.g. NICE, National Dementia Strategy) on day-to-day clinical practice. Dementia in Clinical Practice: A Neurological Perspective is an illustrated, practical resource for medical professionals involved in the assessment and management of dementia patients. It is of particular benefit to neurologists, psychiatrists, geriatricians, primary care practitioners and those working in the fields of neuropsychology, psychology, occupational therapy, speech and language therapy and nursing.
Diagnostic Test Accuracy Studies in Dementia
by A. J. LarnerThis book explains the key steps in planning and executing diagnostic test accuracy studies in dementia, with clear explanations of difficulties and pitfalls and with jargon clearly explained. The emphasis is on pragmatic diagnostic test accuracy studies which can be integrated into day-to-day clinical practice. The book is based on the author's experience over more than 10 years, which has resulted in the publication of many diagnostic test accuracy studies. The text is structured as for a research publication on a diagnostic test accuracy study (Introduction, Methods, Results, Discussion), with a final chapter on Future Prospects. Each of the chapters is devoted to a practical and structured overview of each of these steps in performing and writing up such a study. Diagnostic Test Accuracy Studies in Dementia: A Pragmatic Approach is aimed at any clinician with an interest in dementia disorders: old age psychiatrists, geriatricians, neurologists, neuropsychologists and primary care physicians, as well as other professions allied to medicine. The book is also of interest to any clinician/researcher with an interest in diagnostic test accuracy studies.
Diagnostic Test Accuracy Studies in Dementia: A Pragmatic Approach
by A. J. LarnerThe new and updated edition of this book explains the key steps in planning and executing diagnostic test accuracy studies in dementia, serving as an introduction to the topic with clear explanations of difficulties and pitfalls. It has been fully revised in light of developments over the past 5 years and includes STARD publications which have appeared since the first edition as well as the use of biomarkers of cognitive disorders as increasingly enshrined in diagnostic criteria. The book covers the presentation of study results in terms of measures of discrimination, taking examples from studies in dementia looking at various diagnostic methods including cognitive instruments, neuroimaging, and biochemical studies. The book continues to reflect the author’s own experience in diagnostic test accuracy studies, particularly in the sphere of cognitive screening instruments..Diagnostic Test Accuracy Studies in Dementia encourages clinicians to adopt a pragmatic approach to diagnostic test accuracy studies rooted in day-to-day clinical practice.
Manual of Screeners for Dementia: Pragmatic Test Accuracy Studies
by A. J. LarnerThis book draws on the author’s experience in conducting pragmatic test accuracy studies on screening instruments for dementia/mild cognitive impairment. To facilitate comprehension and assimilation, all data is presented in an easily accessible, succinct and user-friendly way by means of a structured tabular format that allows tests to be easily compared. The pragmatic design of studies ensures high external validity and generalizability for the test results. The book includes a wealth of data on previously presented studies, as well as hitherto unreported test measures (“Number needed” metrics). It presents recently described and new diagnostic metrics (Likelihood to be diagnosed or misdiagnosed; Summary utility index; Number needed for screening utility); data from new studies on screeners (Attended with sign; Free-Cog; Two question depression screener; Jenkins Sleep Questionnaire; Triple test); and previously unpublished data (combination of SMC Likert and MACE; IADL Scale and MMSE). Given its scope, the book will be of interest to all professionals, beginners and seasoned experts alike, whose work involves the assessment of individuals with cognitive (memory) complaints.
Neuropsychological Neurology
by A. J. LarnerEssential to the management of patients suffering from neurological disorders is an understanding of the cognitive aspects of these conditions. This book begins with an outline of the various cognitive domains and how they can be tested, before covering in depth the cognitive deficits seen not only in prototypical neurodegenerative cognitive disorders (Alzheimer's disease, frontotemporal dementias, Huntington's disease, prionoses), but also in other common neurological disorders which may be complicated by cognitive impairment (stroke, multiple sclerosis, Parkinson's disease, brain tumours). This book is an essential reference text for all neurologists, not just those with an interest in cognitive disorders; and for general physicians and specialists who deal with any endocrine, metabolic, vascular, or infective disorders which may compromise cognitive function. Practitioners of professions allied to medicine which involve contact with cognitively impaired patients will also find this text useful.
Teleneurology by Internet and Telephone
by A. J. LarnerMedical information is now widely available on the Internet and through telephone helplines such as NHS Direct and the focus on patient self care is likely to increase. Clinicians in all specialties will often encounter patients who have made self-directed searches for medical information prior to the clinical encounter. Teleneurology by Internet and Telephone is a study of patient information-seeking behaviour in neurology patients prior to referral from primary to secondary care. The book analyses frequency of Internet access and use, and of telephone helpline awareness and use. It also explores use of these modalities over time, use according to patient gender and age and by gender and age over time. Teleneurology by Internet and Telephone is an accessible overview of the utility of these modalities of health information provision and will be of interest not only to neurologists and clinicians in other specialities but also to public health researchers, sociologists and political scientists with an interest in questions of health care provision.
The 2x2 Matrix: Contingency, Confusion and the Metrics of Binary Classification
by A. J. LarnerThis book describes, extends, and illustrates the metrics of binary classification through worked examples.Worked examples based on pragmatic test accuracy study data are used in chapters to illustrate relevance to day-to-day clinical practice. Readers will gain an understanding of sensitivity and specificity and predictive values along with many other parameters.The contents are highly structured, and the use of worked examples facilitates understanding and interpretation.This book is a resource for clinicians in any discipline who are involved in the performance or assessment of test accuracy studies and professionals in the disciplines of machine learning or informatics wishing to gain insight into clinical applications of 2x2 tables.
Transient Global Amnesia
by A. J. LarnerThis brief, accessible book covers all aspects of transient global amnesia (TGA). First, it deals with the history of TGA before moving on to clinical and diagnostic features, and differential diagnosis. The investigation and management of TGA is then discussed, followed by treatment and prognosis. Each of the chapters is devoted to a practical and structured overview of the particular topic, with use of case studies to illustrate the material. Based in part on the author's experience of TGA cases over 15 years and in part on a review of the published literature, this book will hopefully enlighten clinicians from a broad range of medical backgrounds on the clinical features, investigation, and pathogenesis of TGA. Transient Global Amnesia is aimed at any clinician with an interest in, or who encounters patients with, acute amnesia: neurologists, general physicians, old age psychiatrists, geriatricians, clinical neuropsychologists, and primary care physicians, as well as other professions allied to medicine with similar interests, such as members of memory assessment teams.