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ALERT - Adverse Late Effects of Cancer Treatment: Volume 2: Normal Tissue Specific Sites and Systems (Medical Radiology)
by Louis S. Constine Philip Rubin Lawrence B. MarksThe literature on the late effects of cancer treatment is widely scattered in different journals since all major organ systems are affected and management is based on a variety of medical and surgical treatments. The aim of "ALERT - Adverse Late Effects of Cancer Treatment" is to offer a coherent multidisciplinary approach to the care of cancer survivors. The Volume focuses on the general concepts and principles relevant to late effects and on the dynamic interplay of molecular, cytologic and histopathologic events that lead to altered physiologic and metabolic functions and their clinical manifestations. Chapters are also included on legal issues, economic aspects, nursing, psychological issues and quality of life. It is anticipated that this textbook will become the gold standard in providing information on the late effects of cancer treatment and that, in its digitized form, it will be referenced in cancer survivorship guidelines.
Landform - Structure, Evolution, Process Control
by Richard Dikau Jan-Christoph OttoThe book will offer a broad interdisciplinary overview of state of the art research on landform related issues. This includes contributions from Physical Geography (incl. Geomorphology, Ecology, Remote Sensing, Hydrology, and Climatology), Meteorology, Geoinformatics, Cartography, and Computer Science. The book combines introductory/overview papers as well as case studies. The case studies present various new approaches towards a better understanding of the role of landform as a boundary surface between the different earth spheres. Additionally, new methods of handling, modelling and visualisation of digital landform data (incl. digital elevation models, weather forecasting models, hydrological modelling, and ecological modelling) are introduced.
Hydrogel Sensors and Actuators
by Gerald Gerlach K. F. ArndtHydrogels are a fascinating class of polymers which show an immense ability of swelling under the influence of temperature, pH value or concentrations of different species in aqueous solutions. The volume change can amount up to several hundred percent. This unique behaviour is already used in such applications like disposable diapers, contact lenses or drug-delivery systems. The ability to perform mechanical work has been shifted the technical interest more and more towards sensors and actuators exploiting the thermo-chemo-mechano-electrical coupling within hydrogels. The accuracy requirements for such devices are much more demanding than for previous applications. Therefore, a deep knowledge of both the material and the functional properties of hydrogel sensors and actuators is needed. The monograph describes state of the art and recent developments for these materials in sensor and actuator technology.
The Practice of Econometric Theory
by Charles G. RenfroEconometric theory, as presented in textbooks and the econometric literature generally, is a somewhat disparate collection of findings. Its essential nature is to be a set of demonstrated results that increase over time, each logically based on a specific set of axioms or assumptions, yet at every moment, rather than a finished work, these inevitably form an incomplete body of knowledge. The practice of econometric theory consists of selecting from, applying, and evaluating this literature, so as to test its applicability and range. The creation, development, and use of computer software has led applied economic research into a new age. This book describes the history of econometric computation from 1950 to the present day, based upon an interactive survey involving the collaboration of the many econometricians who have designed and developed this software. It identifies each of the econometric software packages that are made available to and used by economists and econometricians worldwide.
Geographic Information Science and Public Participation
by Laxmi RamasubramanianComputer-mediated participation is at the crossroads. In the early heady days of the digital revolution, access to "high" technologies such as GIS promised the empowerment of marginalized communities by providing data and information that was previously hidden away from public view. To a great extent, this goal has been achieved at least in the U.S. and Western Europe - data about a range of government initiatives and raw data about different aspects of spatial planning such as land use, community facilities, property ownership are available a mouse-click away. Now, that we, the public, have access to information, are we able to make better plans for the future of our cities and regions? Are we more inclusive in our planning efforts? Are we able to foster collaborative governance structures mediated by digital technologies? In the book, these issues will be discussed using a three-part structure. The first part of the book will be theoretical - it will review the literature in the field, establish a framework to organize the literature and to link three different subject areas (participation and community development, GIS and other related technologies, and planning processes). The second part of the book will be a series of success stories, case studies that review actual situations where participatory planning using GIS has enabled community wellbeing and empowerment. These case studies will vary in scale and focus on different planning issues (planning broadly defined). The final part of the book will step back to review alternative scenarios for the future, exploring where we are headed, as the technologies we are using to plan rapidly change.
Intraocular Inflammation
by Narsing A. Rao Manfred Zierhut Carlos Pavesio Shigeaki Ohno Fernando OréficeThis well-structured and lavishly illustrated book is a comprehensive reference on intraocular inflammation that encompasses all anatomic forms, settings and etiologies. Individual sections are devoted to uveitis associated with systemic disorders, uveitis syndromes restricted to the eye, bacterial uveitis, viral uveitis, fungal uveitis, parasitic uveitis, uveitis caused by other microbes, traumatic uveitis, and masquerade syndromes. Chapters on the different forms of uveitis are in a homogeneous reader-friendly format, with identification of core messages, explanation of etiology and pathogenesis, up-to-date information on diagnostics and differential diagnosis and guidance on the most appropriate forms of treatment and prognosis. Helpful flow charts are included to assist in identification of potential underlying disorders and the reader will also have online access to one hundred informative case reports demonstrating the different courses of intraocular inflammation. The authors are world experts keen to share their vast experience with the reader. Intraocular Inflammation will be a valuable resource for all physicians who deal with patients with inflammatory eye disease.
Schein's Common Sense Emergency Abdominal Surgery
by Paul Rogers Schein Moshe Robert Lane Ahmad AssaliaEmergency Abdominal Surgery is a battleground for the surgeon - providing character-building experiences, and opportunities for triumph and disaster. In the third edition of this 'simple' book, emergency abdominal surgery is discussed in an informal and no nonsense fashion - as practiced in the 'trenches' of the ER and the OR. The preferred approach for a given situation is discussed in context; it has to fulfill certain prerequisites: save lives, decrease morbidity, be cost effective and be performed correctly.
Springer Handbook of Crystal Growth
by Vishwanath Prasad Michael Dudley Govindhan Dhanaraj Kullaiah ByrappaThe Springer Handbook of Crystal Growth brings together the science and technology of growing crystals, defect characterization and techniques, and understanding the defect formation including defects modelling. This unique effort will provide users with fundamental understanding of crystal growth and defects with the latest instrumentation/ techniques available both for crystal fabrication and defects. Understanding in this rapidly advancing field deals with three main areas: Crystal growth and defect formation, growth methods, and various techniques used in characterization.
Multicriteria Decision Analysis in Geographic Information Science
by Jacek Malczewski Claus RinnerThis book is intended for the GIS Science and Decision Science communities. It is primarily targeted at postgraduate students and practitioners in GIS and urban, regional and environmental planning as well as applied decision analysis. It is also suitable for those studying and working with spatial decision support systems. The main objectives of this book are to effectivley integrate Multicriteria Decision Analysis (MCDA) into Geographic Information Science (GIScience), to provide a comprehensive account of theories, methods, technologies and tools for tackling spatial decision problems and to demonstrate how the GIS-MCDA approaches can be used in a wide range of planning and management situations.
Inherited Metabolic Diseases
by William L. Nyhan Johannes Zschocke Georg F. HoffmannThe explosion of insights in the field of metabolic disease has shed new light on diagnostic as well as treatment options. 'Inherited Metabolic Disease - A Clinical Approach' is written with a reader-friendly consistent structure. It helps the reader to find the information in an easily accessible and rapid way when needed. Starting with an overview of the major groups of metabolic disorders it includes algorithms with questions and answers as well as numerous graphs, metabolic pathways, and an expanded index. Clinical and diagnostic details with a system and symptom based are given to facilitate an efficient and yet complete diagnostic work-up of individual patients.
Data Assimilation: Making Sense of Observations (Nato Science Series: Iv: Ser. #26)
by William Lahoz Boris Khattatov Richard MenardData assimilation methods were largely developed for operational weather forecasting, but in recent years have been applied to an increasing range of earth science disciplines. This book will set out the theoretical basis of data assimilation with contributions by top international experts in the field. Various aspects of data assimilation are discussed including: theory; observations; models; numerical weather prediction; evaluation of observations and models; assessment of future satellite missions; application to components of the Earth System. References are made to recent developments in data assimilation theory (e.g. Ensemble Kalman filter), and to novel applications of the data assimilation method (e.g. ionosphere, Mars data assimilation).
Geoid Determination
by Fernando Sansò Michael G. SiderisThis book will be based on the material of the lecture noties in several International Schools for the Determination and Use of the Geoid, organized by the International Geoid Serivice of the International Association of Geodesy. It consolidates, unifies, and streamlines this material in a unique way not covereed by the few other books that exist on this subjext. More specifically, the book presents (for the first time in a single volume) the theory and methodology of the most common technique used for precise determination of the geoid, including the computation of the marine geoid from satellite altimetry data. These are illustrated by specific examples and actual computations of local geoids. In addition, the book provides the fundamentals of estimating orthometric heights without spirit levelling, by properly combining a geoid with heights from GPS. Besides the geodectic and geophysical uses, this last application has made geoid computation methods very popular in recent years because the entire GPS and GIS user communities are interested in estimating geoid undulations in order to convert GPS heights to physically meaningful orthometric heights (elevations above mean sea level). The overall purpose of the book is, therefore, to provide the user community (academics, graduate students, geophysicists, engineers, oceanographers, GIS and GPS users, researchers) with a self-contained textbook, which will supply them with the complete roadmap of estimating geoid undulations, from the theoretical definitions and formulas to the available numerical methods and their implementation and the test in practice.
Springer Handbook of Medical Technology
by Robert Steven Pozos Klaus-Peter Hoffmann Rüdiger KrammeThis concise, user-oriented and up-to-date desk reference offers a broad introduction to the fascinating world of medical technology, fully considering today's progress and further development in all relevant fields. The Springer Handbook of Medical Technology is a systemized and well-structured guideline which distinguishes itself through simplification and condensation of complex facts. This book is an indispensable resource for professionals working directly or indirectly with medical systems and appliances every day. It is also meant for graduate and post graduate students in hospital management, medical engineering, and medical physics.
International Practices in Pancreatic Surgery
by Markus W. Büchler Michael G. Sarr Hans Lippert René Mantke"International Practices in Pancreatic Surgery" describes in great detail general and specific technical aspects of the standard resection procedures of the pancreas. Each surgical step during the pancreatic operation is precisely outlined and accompanied by drawings and photographs. The main chapters on pancreatic carcinoma, chronic and acute pancreatitis are written by the editors. An international faculty complements the texts by describing their own personal techniques. This concept offers the greatest possible overview of the techniques used by experienced surgeons.
Geological Methods in Mineral Exploration and Mining
by Roger MarjoribanksThis practical step-by-step guide describes the key geological field techniques needed by today's exploration geologists involved in the search for metallic deposits. The techniques described are fundamental to the collection, storage and presentation of geological data and their use to locate ore. This book explains the various tasks which the exploration geologist is asked to perform in the sequence in which they might be employed in an actual exploration project. Hints and tips are give. The steps are illustrated with numerous examples drawn from real projects on which the author has worked. The book emphasizes traditional skills and shows how they can be combined effectively with modern technological approaches.
Unternehmensbewertung
by Christoph Kuhner Helmut MaltryEinf#65533;hrung in alle relevanten Ans#65533;tze der Unternehmensbewertung, die in Theorie und Bewertungspraxis diskutiert werden. Ausgehend von den verschiedenen rechtlich bzw. wirtschaftlich motivierten Anl#65533;ssen einer Unternehmensbewertung sowie der Darstellung der dogmengeschichtlichen Entwicklung in Deutschland wird die Unternehmensbewertung investitionstheoretisch fundiert. Das Prognoseproblem und das Kapitalisierungsproblem werden getrennt voneinander betrachtet.
Skull Base Surgery (Springer Surgery Atlas Series)
by Anthony Cheesman Ghassan Alusi H. Ian Sabin'Skull Base Surgery' represents genuinely multi-disciplinary collaborative approach to the standard procedures in skull base surgery. It emphasizes the basic operative steps of each approach and describes variations from the basic approach. Authors from the relevant specialties Neurosurgery, Otolaryngology, Maxillo-Facial Surgery and Plastic Surgery contribute to this new specialty of skull base surgery.
Anatomic Basis of Tumor Surgery
by John E. Skandalakis William C. Wood Charles Staley Sean MooreModern biological understanding is the basis for a multimodality treatment of a tumor. 'Anatomic Basis of Tumor Surgery' is the only book that provides an anatomic basis and description of tumor surgery based on an understanding of both the anatomy and biology of tumor progression. It presents the regional anatomy to allow tailoring of the operation as demanded.
Petrogenesis of Metamorphic Rocks
by Rodney Grapes Kurt BucherPetrogenesis of Metamorphic Rocks presents a large number of diagrams showing the stability relations among minerals and groups of minerals found in metamorphic rocks. The diagrams help to determine the pressure and temperature conditions under which a given set of metamorphic rocks may have formed. Other parameters that control metamorphic mineral assemblages are also discussed and pitfalls resulting from simplifications and generalizations are highlighted. The book discusses the most common metamorphic rock types, their nomenclature, structure and graphical representation of their mineral assemblages. Part I defines basic principles of metamorphism, introduces metamorphic processes, geologic thermometry and barometry and defines metamorphic grade. Part II presents in a systematic way mineralogical changes and assemblages found in the most common types of metamorphic rocks. The computation of diagrams is based on recent advances in quantitative petrology and geochemistry. An extensive bibliography, including the key contributions and classic papers in the field, make it an invaluable source book for graduate students and professional geologists.
EUROHIP
by Wolfhart Puhl Karsten E. Dreinhöfer Klaus-Peter Günther Paul DieppeMost developed countries are struggling to finance first-class health care for everyone in their community, leading to renewed emphasis on appropriate and equitable provision of health care, placing interventions that are both high in volume and expense under the microscope. This book provides readers with an understanding of the key issues that dictate the provision of total hip replacement, one of the most cost-effective procedures available within health care. A highlight of the book is its multinational and multidisciplinary approach presenting perspectives from public health, individual patients and doctors, economists and health care purchasers and managers.
Control of Biofilm Infections by Signal Manipulation (Springer Series on Biofilms #2)
by Naomi Balaban J. W. CostertonThe number of patients affected by and dying from what can be considered as a "biofilm disease" is higher than heart disease and cancer combined. Thus, this is a hugely important work that describes the molecular mechanisms of cell-to-cell communication among bacterial cells in a biofilm, the development of antibiofilm inhibitors such as quorum-sensing inhibitors, and the use of biofilm inhibitors to prevent and treat bacterial infections in humans and other animals.
Reviews of Physiology, Biochemistry and Pharmacology 159
by S. Offermanns S. G. Amara E. Bamberg S. C. Hebert R. Jahn W. J. Lederer R. Lill A. Miyajima T. Gudermann R. Zechner B. FleischmannThis volume presents a neural network architecture for the prediction of conditional probability densities - which is vital when carrying out universal approximation on variables which are either strongly skewed or multimodal. Two alternative approaches are discussed: the GM network, in which all parameters are adapted in the training scheme, and the GM-RVFL model which draws on the random functional link net approach. Points of particular interest are: - it examines the modification to standard approaches needed for conditional probability prediction; - it provides the first real-world test results for recent theoretical findings about the relationship between generalisation performance of committees and the over-flexibility of their members; This volume will be of interest to all researchers, practitioners and postgraduate / advanced undergraduate students working on applications of neural networks - especially those related to finance and pattern recognition.
Transplantation Surgery: A Companion To Specialist Surgical Practice (Springer Surgery Atlas Series)
by Gabriel C. Oniscu John L. R. Forsythe Elizabeth A. PomfretThis atlas provides transplant professionals with a step-wise approach to organ transplantation, illustrating the technical steps and highlighting practice points for each procedure. All aspects of abdominal and thoracic transplantation are covered, including organ retrieval, bench preparation and implantation. Separate chapters address specific technical issues for heart and lung, liver, kidney, pancreas and intestinal transplantation, providing detailed approaches to difficult situations. Technical variations are clearly explained, and tips are provided on how to ensure safe and efficient surgery. Transplant surgeons, trainees, fellows and other professionals involved in transplantation will find this book to be an ideal reference point. It has been written by an experienced international team of authors who have pioneered many of the techniques described.
Sparking Signals
by Gottfried Baier Ulrich Zügel Burkhart Schraven Arne Von BoninThe importance of the protein kinase family is underscored by numerous disease states that arise due to dysregulation of kinase activity. Recent progress in understanding the molecular regulation of kinases has led to the development of new therapeutics based on the inhibition of kinase activity. In this book, well known experts present their most recent findings on the fast developing kinase field. It will be of interest to basic researchers and the pharmaceutical industry.
Organocatalysis
by Hilmar Weinmann Benjamin List Stefan Jaroch Manfred ReetzThis book provides an excellent overview on state-of-the-art of modern organocatalysis. It presents the contributions from leading experts, with backgrounds in academia and industry, to an Ernst Schering Research Foundation Symposium held in April 2007. It will be of interest to those who want a general overview of the topic, but also to those who want to learn more about the state-of-the-art, current trends and perspectives in this highly dynamic field of research.